A 'three-pronged' binding mechanism for the SAP/SH2D1A SH2 domain: Structural basis and relevance to the XLP syndrome

EMBO Journal

Volumn 21, Issue 3, 2002, Pages 314-323

  Hwang, Peter M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Immunodeficiency; SAP; SH2 domain; SH2D1A; XLP

Indexed keywords

AMINO ACID; CELL SURFACE RECEPTOR; GENE PRODUCT; HYDROGEN; SIGNALING LYMPHOCYTE ACTIVATION MOLECULE ASSOCIATED PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; HEMATOPOIETIC CELL; IMMUNE DEFICIENCY; LYMPHOPROLIFERATIVE DISEASE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MOTIF; PROTON TRANSPORT; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; X LINKED LYMPHOPROLIPHERATIVE SYNDROME;

ANTIGENS, CD; CARRIER PROTEINS; CONSENSUS SEQUENCE; GLYCOPROTEINS; HUMANS; IMMUNOGLOBULINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOPROLIFERATIVE DISORDERS; MUTATION; PEPTIDE MAPPING; PHOSPHORYLATION; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SRC HOMOLOGY DOMAINS; TYROSINE;

EID: 18244395893     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.3.314     Document Type: Article

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