X-linked lymphoproliferative disease: 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells

Journal of Experimental Medicine

Volumn 192, Issue 3, 2000, Pages 337-346

  Parolini, Silvia ^a   Bottino, Cristina ^b   Falco, Michela ^c   Augugliaro, Raffaella ^b   Giliani, Silvia ^d   Franceschini, Roberta ^d   Ochs, Hans D ^e   Wolf, Hermann ^f   Bonnefoy, Jean Yves ^g   Biassoni, Roberto ^b   Moretta, Lorenzo ^b,c   Notarangelo, Luigi D ^d   Moretta, Alessandro ^c  

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d UNIVERSITY OF BRESCIA   (Italy)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF VIENNA   (Austria)

^g Centre d'Immunologie Pierre Fabre   (France)

Author keywords

2B4 molecule; Epstein Barr virus infection; Natural cytotoxicity receptor; Natural killer cell; X linked lymphoproliferative disease

Indexed keywords

CD16 ANTIGEN; CD48 ANTIGEN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; EPSTEIN BARR VIRUS; GENE MUTATION; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOPROLIFERATIVE DISEASE; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTIGENS, CD; BASE SEQUENCE; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; CHILD, PRESCHOOL; DNA, COMPLEMENTARY; HERPESVIRUS 4, HUMAN; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KILLER CELLS, NATURAL; LINKAGE (GENETICS); LYMPHOCYTE ACTIVATION; LYMPHOPROLIFERATIVE DISORDERS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; X CHROMOSOME;

EID: 0034618065     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.3.337     Document Type: Article

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