Established and emerging fluorescence-based assays for G-protein function: Ras-superfamily GTPases

Combinatorial Chemistry and High Throughput Screening

Volumn 6, Issue 4, 2003, Pages 409-418

  Rojas, Rafael J ^a   Kimple, Randall J ^a   Rossman, Kent L ^b   Siderovskil, David P ^a,b   Sondek, John ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Fluorescent nucleotide exchange assay; Ras; Rho; Small GTPase

Indexed keywords

GUANOSINE TRIPHOSPHATASE; RAS PROTEIN; RHO FACTOR;

ANALYTIC METHOD; BIOASSAY; CANCER GROWTH; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME STRUCTURE; FLUOROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION;

EID: 0038284829     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: 10.2174/138620703106298509     Document Type: Review

References (66)

1. Ehrhardt, A.; Ehrhardt, G.R.; Guo, X.; Schrader, J.W. Exp. Hematol., 2002, 30, 1089-106.
2. Vojtek, A.B.; Der, C.J. J. Biol. Chem., 1998, 273, 19925-8.
3. Shields, J.M.; Pruitt, K.; McFall, A.; Shaub, A.; Der, C.J. Trends Cell Biol., 2000, 10, 147-54.
4. Reuther, G.W.; Der, C.J. Curr. Opin. Cell Biol., 2000, 12, 157-65.
5. Etienne-Manneville, S.; Hall, A. Nature, 2002, 420, 629-35.
6. Hall, A. Science, 1998, 279, 509-14.
7. Frame, M.C.; Brunton, V.G. Curr. Opin. Genet. Dev., 2002, 12, 36-43.
8. Evers, E.E.; Zondag, G.C.; Malliri, A.; Price, L.S.; ten Klooster, J.P.; van der Kammen, R.A.; Collard, J.G. Eur. J. Cancer, 2000, 36, 1269-74.
9. Boettner, B.; Van Aelst, L. Gene, 2002, 286, 155-74.
10. Sahai, E.; Marshall, C.J. Nat. Rev. Cancer, 2002, 2, 133-42.
11. Oxford, G.; Theodorescu, D. Cancer Lett., 2003, 189, 117-28.
12. Fritz, G.; Brachetti, C.; Bahlmann, F.; Schmidt, M.; Kaina, B. Br. J. Cancer, 2002, 87, 635-44.
13. Fritz, G.; Just, I.; Kaina, B. Int. J. Cancer, 1999, 81, 682-7.
14. Clark, E.A.; Golub, T.R.; Lander, E.S.; Hynes, R.O. Nature, 2000, 406, 532-5.
15. Kleer, C.G.; van Golen, K.L.; Zhang, Y.; Wu, Z.F.; Rubin, M.A.; Merajver, S.D. Am. J. Pathol., 2002, 160, 579-84.
16. Whitehead, I.P.; Campbell, S.; Rossman, K.L.; Der, C.J. Biochim. Biophys. Acta, 1997, 1332, F1-23.
17. Schmidt, A.; Hall, A. Genes Dev., 2002, 16, 1587-609.
18. Downward, J. Nat. Rev. Cancer, 2003, 3, 11-22.
19. Pai, E.F.; Kabsch, W.; Krengel, U.; Holmes, K.C.; John, J.; Wittinghofer, A. Nature, 1989, 341, 209-14.
20. de Vos, A.M.; Tong, L.; Milburn, M.V.; Matias, P.M.; Jancarik, J.; Noguchi, S.; Nishimura, S.; Miura, K.; Ohtsuka, E.; Kim, S.H. Science, 1988, 239, 888-93.
21. Hirshberg, M.; Stockley, R.W.; Dodson, G.; Webb, M.R. Nat. Struct. Biol., 1997, 4, 147-52.
22. Nassar N.; Horn, G.; Herrmann C.; Scherer A.; McCormick F.; Wittinghofer A. Nature, 1995, 375, 554-60.
23. Scheffzek, K.; Klebe, C.; Fritz-Wolf, K.; Kabsch, W.; Wittinghofer, A. Nature, 1995, 374, 378-81.
24. Vetter, I.R.; Wittinghofer, A. Science, 2001, 294, 1299-304.
25. Hall, A.; Self, A.J. J Biol. Chem., 1986, 261, 10963-5.
26. Porfiri, E.; Hancock, J.F. Methods Enzymol., 1995, 256, 85-90.
27. Self, A.J.; Hall, A. Methods Enzymol., 1995, 256, 67-76.
28. Zheng, Y.; Hart, M.J.; Cerione, R.A. Methods Enzymol., 1995, 256, 77-84.
29. Lenzen, C.; Cool, R.H.; Wittinghofer, A. Methods Enzymol., 1995, 255, 95-109.
30. McEwen, D.P.; Gee, K.R.; Kang, H.C.; Neubig, R.R. Anal. Biochem., 2001, 291, 109-17.
31. Hiratsuka, T. Biochim. Biophys. Acta, 1983, 742, 496-508.
32. Neal, S.E.; Eccleston, J.F.; Webb, M.R. Proc. Natl. Acad. Sci. USA, 1990, 87, 3562-5.
33. Remmers, A.E.; Posner, R.; Neubig, R.R. J. Biol. Chem., 1994, 269, 13771-8.
34. Remmers, A.E. Anal. Biochem., 1998, 257, 89-94.
35. Remmers, A.E.; Neubig, R.R. J Biol. Chem., 1996, 271, 4791-7.
36. John, J.; Sohmen, R.; Feuerstein, J.; Linke, R.; Wittinghofer, A.; Goody, R.S. Biochemistry, 1990, 29, 6058-65.
37. Scheidig, A.J.; Franken, S.M.; Corrie, J.E.; Reid, G.P.; Wittinghofer, A.; Pai, E.F.; Goody, R.S. J. Mol. Biol., 1995, 253, 132-50.
38. Boriack-Sjodin, P.A.; Margarit, S.M.; Bar-Sagi, D.; Kuriyan, J. Nature, 1998, 394, 337-43.
39. Snyder, J.T.; Worthylake, D.K.; Rossman, K.L.; Betts, L.; Pruitt, W.M.; Siderovski, D.P.; Der, C.J.; Sondek, J. Nat. Struct. Biol., 2002, 9, 468-75.
40. Renault, L.; Kuhlmann, J.; Henkel, A.; Wittinghofer, A. Cell, 2001, 105, 245-55.
41. Rossman, K.L.; Worthylake, D.K.; Snyder, J.T.; Siderovski, D.P.; Campbell, S.L.; Sondek, J. EMBO J., 2002, 21, 1315-26.
42. Worthylake, D.K.; Rossman, K.L.; Sondek, J. Nature, 2000, 408, 682-8.
43. Rossman, K.L.; Worthylake, D.K.; Snyder, J.T.; Cheng, L.; Whitehead, I.P.; Sondek, J. J. Biol. Chem., 2002, 277, 50893-8.
44. Papp, S.; Vanderkooi, J.M. Photochem. Photobiol., 1989, 49, 775-84.
45. Selvin, P.R. Methods Enzymol., 1995, 246, 300-34.
46. Skelly, J.V.; Suter, D.A.; Kuroda, R.; Neidle, S.; Hancock, J.F.; Drake, A. FEBS Lett., 1990, 262, 127-30.
47. Antonny, B.; Chardin, P.; Roux, M.; Chabre, M. Biochemistry, 1991, 30, 8287-95.
48. Hahn, K.; Toutchkine, A. Curr. Opin. Cell Biol., 2002, 14, 167-72.
49. Gardiner, E.M.; Pestonjamasp, K.N.; Bohl, B.P.; Chamberlain, C.; Hahn, K.M.; Bokoch, G.M. Curr. Biol., 2002, 12, 2029-34.
50. Macara, I.G. Dev. Cell, 2002, 2, 379-80.
51. Bos, J.L. Nature, 2001, 411, 1006-7.
52. Kraynov, V.S.; Chamberlain, C.; Bokoch, G.M.; Schwartz, M.A.; Slabaugh, S.; Hahn, K.M. Science, 2000, 290, 333-7.
53. Del Pozo, M.A.; Kiosses, W.B.; Alderson, N.B.; Meller, N.; Hahn, K.M.; Schwartz, M.A. Nat. Cell Biol., 2002, 4, 232-9.
54. Tzima, E.; Del Pozo, M.A.; Kiosses, W.B.; Mohamed, S.A.; Li, S.; Chien, S.; Schwartz, M.A. EMBO J., 2002, 21, 6791-800.
55. Kalab, P.; Weis, K.; Heald, R. Science, 2002, 295, 2452-6.
56. Plafker, K.; Macara, I.G. J. Biol. Chem., 2002, 277, 30121-7.
57. Itoh, R.E.; Kurokawa, K.; Ohba, Y.; Yoshizaki, H.; Mochizuki, N.; Matsuda, M. Mol. Cell. Biol., 2002, 22, 6582-6591.
58. Mochizuki, N.; Yamashita, S.; Kurokawa, K.; Ohba, Y.; Nagai, T.; Miyawaki, A.; Matsuda, M. Nature, 2001, 411, 1065-8.
59. Nassar, N.; Horn, G.; Herrmann, C.; Scherer, A.; McCormick, F.; Wittinghofer, A. Nature, 1995, 375, 554-60.
60. Morreale, A.; Venkatesan, M.; Mott, H.R.; Owen, D.; Nietlispach, D.; Lowe, P.N.; Laue, E.D. Nat. Struct. Biol., 2000, 7, 384-8.
61. Herrmann, C.; Horn, G.; Spaargaren, M.; Wittinghofer, A. J. Biol. Chem., 1996, 271, 6794-800.
62. Herrmann, C.; Martin, G.A.; Wittinghofer, A. J. Biol. Chem., 1995, 270, 2901-5.
63. Kuhlmann, J.; Macara, I.; Wittinghofer, A. Biochemistry, 1997, 36, 12027-35.
64. Traver, S.; Bidot, C.; Spassky, N.; Baltauss, T.; De Tand, M.F.; Thomas, J.L.; Zalc, B.; Janoueix-Lerosey, I.; Gunzburg, J.D. Biochem. J., 2000, 350 Pt 1, 19-29.
65. Kimple, R.J.; De Vries, L.; Tronchere, H.; Behe, C.I.; Morris, R.A.; Gist Farquhar, M.; Siderovski, D.P. J Biol. Chem., 2001, 276, 29275-81.
66. Graham, D.L.; Lowe, P.N.; Chalk, P.A. Anal. Biochem., 2001, 296, 208-17.