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Volumn 36, Issue 10, 2000, Pages 1269-1274

Rho family proteins in cell adhesion and cell migration

Author keywords

Adherens junctions; Cell migration; E cadherin; Rac; Rho; Tiam1

Indexed keywords

CADHERIN; GUANOSINE TRIPHOSPHATASE; RAC PROTEIN; RHO FACTOR; UVOMORULIN;

EID: 0034051228     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(00)00091-5     Document Type: Conference Paper
Times cited : (202)

References (49)
  • 1
    • 0028245813 scopus 로고
    • Cadherin expression in carcinomas: Role in the formation of cell junctions and the prevention of invasiveness
    • Birchmeier W, Behrens J. Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness. Biochim Biophys Acta 1994, 1198, 11-26.
    • (1994) Biochim Biophys Acta , vol.1198 , pp. 11-26
    • Birchmeier, W.1    Behrens, J.2
  • 3
    • 0025752664 scopus 로고
    • The 102 kd cadherinassociated protein: Similarity to vinculin and post-transcriptional regulation of expression
    • Nagafuchi A, Takeichi M, Tsukita S. The 102 kd cadherinassociated protein: similarity to vinculin and post-transcriptional regulation of expression. Cell 1991, 65, 849-857.
    • (1991) Cell , vol.65 , pp. 849-857
    • Nagafuchi, A.1    Takeichi, M.2    Tsukita, S.3
  • 4
    • 0028979956 scopus 로고
    • Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin
    • Knudsen KA, Soler AP, Johnson KR, Wheelock MJ. Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol 1995, 130, 67-77.
    • (1995) J Cell Biol , vol.130 , pp. 67-77
    • Knudsen, K.A.1    Soler, A.P.2    Johnson, K.R.3    Wheelock, M.J.4
  • 5
    • 0026316099 scopus 로고
    • A homolog of the Armadillo protein in Drosophila (Plakoglobin) associated with ECadherin
    • McCrea PD, Turck CW, Gumbiner B. A homolog of the Armadillo protein in Drosophila (Plakoglobin) associated with ECadherin. Science 1991, 254, 1359-1361.
    • (1991) Science , vol.254 , pp. 1359-1361
    • McCrea, P.D.1    Turck, C.W.2    Gumbiner, B.3
  • 6
    • 0028258445 scopus 로고
    • Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin
    • Hinck L, Nelson WJ, Papkoff J. Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin. J Cell Biol 1994, 124, 729-741.
    • (1994) J Cell Biol , vol.124 , pp. 729-741
    • Hinck, L.1    Nelson, W.J.2    Papkoff, J.3
  • 7
    • 1842390685 scopus 로고
    • Cell binding function of E-cadherin is regulated by the cytoplasmic domain
    • Nagafuchi A, Takeichi M. Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J 1988, 7, 3679-3684.
    • (1988) EMBO J , vol.7 , pp. 3679-3684
    • Nagafuchi, A.1    Takeichi, M.2
  • 8
    • 0025374899 scopus 로고
    • Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule
    • Ozawa M, Ringwald M, Kemler R. Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc Nail Acad Sci USA 1990, 87, 4246-4250.
    • (1990) Proc Nail Acad Sci USA , vol.87 , pp. 4246-4250
    • Ozawa, M.1    Ringwald, M.2    Kemler, R.3
  • 9
    • 0026602806 scopus 로고
    • Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain
    • Kintner C. Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain. Cell 1992, 69, 225-236.
    • (1992) Cell , vol.69 , pp. 225-236
    • Kintner, C.1
  • 10
    • 0024383791 scopus 로고
    • Dissecting tumor cell invasion: Epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion
    • Behrens J, Mareel MM, Van Roy FM, Birchmeier W. Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol 1989, 108, 2435-2447.
    • (1989) J Cell Biol , vol.108 , pp. 2435-2447
    • Behrens, J.1    Mareel, M.M.2    Van Roy, F.M.3    Birchmeier, W.4
  • 11
    • 0025818032 scopus 로고
    • Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
    • Vleminckx K, Vakaet L Jr, Mareel M, Fiers W, Van Roy F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991, 66, 107-119.
    • (1991) Cell , vol.66 , pp. 107-119
    • Vleminckx, K.1    Vakaet Jr., L.2    Mareel, M.3    Fiers, W.4    Van Roy, F.5
  • 13
    • 0028100547 scopus 로고
    • Mutations of the E-cadherin gene in human gynecologic cancers
    • Risinger JI, Berchuck A, Kohler MF, Boyd J. Mutations of the E-cadherin gene in human gynecologic cancers. Nat Genet 1994, 7, 98-102.
    • (1994) Nat Genet , vol.7 , pp. 98-102
    • Risinger, J.I.1    Berchuck, A.2    Kohler, M.F.3    Boyd, J.4
  • 14
    • 0029558476 scopus 로고
    • E-cadherin is a tumour invasion suppressor gene mutated in human lobular breast cancers
    • Berx G, Cleton Jansen AM, Nollet F, et al. E-cadherin is a tumour invasion suppressor gene mutated in human lobular breast cancers. EMBO J 1995, 14, 6107-6115.
    • (1995) EMBO J , vol.14 , pp. 6107-6115
    • Berx, G.1    Cleton Jansen, A.M.2    Nollet, F.3
  • 15
    • 0029810444 scopus 로고    scopus 로고
    • Prognostic value of cadherin-associated molecules (alpha-, beta-, and gamma-catenins and p120(cas)) in bladder tumors
    • Shimazui T, Schalken JA, Giroldi LA, et al. Prognostic value of cadherin-associated molecules (alpha-, beta-, and gamma-catenins and p120(cas)) in bladder tumors. Cancer Res 1996, 56, 4154-4158.
    • (1996) Cancer Res , vol.56 , pp. 4154-4158
    • Shimazui, T.1    Schalken, J.A.2    Giroldi, L.A.3
  • 16
    • 0026630994 scopus 로고
    • Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization
    • Hirano S, Kimoto N, Shimoyama Y, Hirohashi S, Takeichi M. Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization. Cell 1992, 70, 293-301.
    • (1992) Cell , vol.70 , pp. 293-301
    • Hirano, S.1    Kimoto, N.2    Shimoyama, Y.3    Hirohashi, S.4    Takeichi, M.5
  • 17
    • 0027738023 scopus 로고
    • Association of the ape gene product with beta-catenin
    • Rubinfeld B, Souza B, Albert I, et al. Association of the ape gene product with beta-catenin. Science 1993, 262, 1731-1734.
    • (1993) Science , vol.262 , pp. 1731-1734
    • Rubinfeld, B.1    Souza, B.2    Albert, I.3
  • 18
    • 0028572556 scopus 로고
    • E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton
    • Hulsken J, Birchmeier W, Behrens J. E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. J Cell Biol 1994, 127, 2061-2069.
    • (1994) J Cell Biol , vol.127 , pp. 2061-2069
    • Hulsken, J.1    Birchmeier, W.2    Behrens, J.3
  • 19
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of beta-catenin with the transcription factor LEF-1
    • Behrens J, Vonkries JP, Kühl M, et al. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996, 382, 638-642.
    • (1996) Nature , vol.382 , pp. 638-642
    • Behrens, J.1    Vonkries, J.P.2    Kühl, M.3
  • 20
    • 0001003110 scopus 로고    scopus 로고
    • XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
    • Molenaar M, Vandewetering M, Oosterwegel M, et al. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 1996, 86, 391-399.
    • (1996) Cell , vol.86 , pp. 391-399
    • Molenaar, M.1    Vandewetering, M.2    Oosterwegel, M.3
  • 21
    • 0030975671 scopus 로고    scopus 로고
    • Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/-colon carcinoma
    • Korinek V, Barker N, Morin PJ, et al. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/-colon carcinoma. Science 1997, 275, 1784-1787.
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3
  • 22
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-cateninTcf signalling in colon cancer by mutations in beta-catenin or APC
    • Morin PC, Sparks AB, Kronek V, et al. Activation of beta-cateninTcf signalling in colon cancer by mutations in beta-catenin or APC. Science 1997, 275, 1787-1790.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.C.1    Sparks, A.B.2    Kronek, V.3
  • 24
    • 0027732538 scopus 로고
    • Proteins regulating ras and its relatives
    • Boguski MS, McCormick F. Proteins regulating ras and its relatives. Nature 1993, 366, 643-654.
    • (1993) Nature , vol.366 , pp. 643-654
    • Boguski, M.S.1    McCormick, F.2
  • 25
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signalling networks
    • Aelst L, D'Souza-Schorey C. Rho GTPases and signalling networks. Genes Dev 1997, 11, 2295-2322.
    • (1997) Genes Dev , vol.11 , pp. 2295-2322
    • Aelst, L.1    D'Souza-Schorey, C.2
  • 26
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. Rho GTPases and the actin cytoskeleton. Science 1998, 279, 509-514.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 27
    • 0030968177 scopus 로고    scopus 로고
    • The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
    • Braga VMM, Machesky LM, Hall A, Hotchin NA. The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J Cell Biol 1997, 137, 1421-1431.
    • (1997) J Cell Biol , vol.137 , pp. 1421-1431
    • Braga, V.M.M.1    Machesky, L.M.2    Hall, A.3    Hotchin, N.A.4
  • 28
    • 0030718609 scopus 로고    scopus 로고
    • Regulation of cell-cell adhesion by Rac and Rho small G proteins in MDCK cells
    • Takaishi K, Sasaki T, Kotani H, Nishioka H, Takai Y. Regulation of cell-cell adhesion by Rac and Rho small G proteins in MDCK cells. J Cell Biol 1997, 139, 1047-1059.
    • (1997) J Cell Biol , vol.139 , pp. 1047-1059
    • Takaishi, K.1    Sasaki, T.2    Kotani, H.3    Nishioka, H.4    Takai, Y.5
  • 30
    • 0032583205 scopus 로고    scopus 로고
    • Matrix-dependent Tiaml/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase
    • Sander EE, van Delft S, ten Klooster J-P, et al. Matrix-dependent Tiaml/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase. J Cell Biol 1998, 143, 1385-1398.
    • (1998) J Cell Biol , vol.143 , pp. 1385-1398
    • Sander, E.E.1    Van Delft, S.2    Ten Klooster, J.-P.3
  • 31
    • 0028225439 scopus 로고
    • Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins
    • Habets GGM, Scholtes EHM, Zuydgeest D, et al. Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell 1994, 77, 537-549.
    • (1994) Cell , vol.77 , pp. 537-549
    • Habets, G.G.M.1    Scholtes, E.H.M.2    Zuydgeest, D.3
  • 34
    • 0029820714 scopus 로고    scopus 로고
    • 1 integrin is required for the collagen and FGF-1 induced cell dispersion in a rat bladder carcinoma cell line
    • 1 integrin is required for the collagen and FGF-1 induced cell dispersion in a rat bladder carcinoma cell line. Cell Adhes Commun 1996, 4, 187-199.
    • (1996) Cell Adhes Commun , vol.4 , pp. 187-199
    • Vallès, A.M.1    Boyer, B.2    Tarone, G.3    Thiery, J.P.4
  • 35
    • 0031459917 scopus 로고    scopus 로고
    • Cdc42 and Racl induce integrin-mediated cell motility and invasiveness through PI(3)K
    • Keely PJ, Westwick JK, Whitehead IP, Der CJ, Parise LV. Cdc42 and Racl induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature 1997, 390, 632-635.
    • (1997) Nature , vol.390 , pp. 632-635
    • Keely, P.J.1    Westwick, J.K.2    Whitehead, I.P.3    Der, C.J.4    Parise, L.V.5
  • 36
    • 0026778133 scopus 로고
    • The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • Ridley AJ, Hall A. The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992, 70, 389-399.
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 37
    • 0028961293 scopus 로고
    • Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes CD, Hall A. Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995, 81, 53-62.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 38
    • 0033584865 scopus 로고    scopus 로고
    • Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42
    • Reid T, Bathoorn A, Ahmadian MR, Collard JG. Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42. J Biol Chem 1999, 274, 33587-33593.
    • (1999) J Biol Chem , vol.274 , pp. 33587-33593
    • Reid, T.1    Bathoorn, A.2    Ahmadian, M.R.3    Collard, J.G.4
  • 39
    • 0033615966 scopus 로고    scopus 로고
    • Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
    • Sander EE, ten Klooster J-P, van Delft S, van der Kammen RA, Collard JG. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol 1999, 147, 1009-1022.
    • (1999) J Cell Biol , vol.147 , pp. 1009-1022
    • Sander, E.E.1    Ten Klooster, J.-P.2    Van Delft, S.3    Van Der Kammen, R.A.4    Collard, J.G.5
  • 40
    • 0033174147 scopus 로고    scopus 로고
    • Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading
    • van Leeuwen FN, van Delft S, Kain HE, van der Kammen RA, Collard JG. Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading. Nature Cell Biol 1999, 1, 242-248.
    • (1999) Nature Cell Biol , vol.1 , pp. 242-248
    • Van Leeuwen, F.N.1    Van Delft, S.2    Kain, H.E.3    Van Der Kammen, R.A.4    Collard, J.G.5
  • 41
    • 0029889591 scopus 로고    scopus 로고
    • Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain
    • Reid T, Furuyashiki T, Ishizaki T, et al. Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain. J Biol Chem 1996, 271, 13556-13560.
    • (1996) J Biol Chem , vol.271 , pp. 13556-13560
    • Reid, T.1    Furuyashiki, T.2    Ishizaki, T.3
  • 42
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • Ren X-D, Kiosses WB, Schwartz MA. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J 1999, 18, 578-585.
    • (1999) EMBO J , vol.18 , pp. 578-585
    • Ren, X.-D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 43
    • 0033605738 scopus 로고    scopus 로고
    • Inhibition of myosin light chain kinase by p21-activated kinase
    • Sanders LC, Matsamura F, Bokoch GM, de Lanerolle P. Inhibition of myosin light chain kinase by p21-activated kinase. Science 1999, 283, 2083-2085.
    • (1999) Science , vol.283 , pp. 2083-2085
    • Sanders, L.C.1    Matsamura, F.2    Bokoch, G.M.3    De Lanerolle, P.4
  • 44
    • 0033577902 scopus 로고    scopus 로고
    • P21-activated kinase 1 (Pakl) regulates cell motility in mammalian fibroblasts
    • Sells MA, Boyd JT, Chernoff J. P21-activated kinase 1 (Pakl) regulates cell motility in mammalian fibroblasts. J Cell Biol 1999, 145, 837-849.
    • (1999) J Cell Biol , vol.145 , pp. 837-849
    • Sells, M.A.1    Boyd, J.T.2    Chernoff, J.3
  • 45
    • 0025734655 scopus 로고
    • Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET
    • Naldini L, Vigna E, Narsimhan R, et al. Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. Oncogene 1991, 6, 501-504.
    • (1991) Oncogene , vol.6 , pp. 501-504
    • Naldini, L.1    Vigna, E.2    Narsimhan, R.3
  • 46
    • 0028894787 scopus 로고
    • Regulation of scatter factor/ hepatocyte growth factor responses by ras, Rac, and Rho in MDCK cells
    • Ridley AJ, Comoglio PM, Hall A. Regulation of scatter factor/ hepatocyte growth factor responses by ras, Rac, and Rho in MDCK cells. Mol Cell Biol 1995, 15, 1110-1122.
    • (1995) Mol Cell Biol , vol.15 , pp. 1110-1122
    • Ridley, A.J.1    Comoglio, P.M.2    Hall, A.3
  • 47
    • 0030911052 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by ras
    • Rodriguez-Viciana P, Warne PH, Khwaja A, et al. Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by ras. Cell 1997, 89, 457-467.
    • (1997) Cell , vol.89 , pp. 457-467
    • Rodriguez-Viciana, P.1    Warne, P.H.2    Khwaja, A.3
  • 48
    • 0033575885 scopus 로고    scopus 로고
    • EPS8 and E3B1 transduce signals from ras to Rac
    • Scita G, Nordstrom J, Carbone R, et al. EPS8 and E3B1 transduce signals from ras to Rac. Nature 1999, 401, 290-293.
    • (1999) Nature , vol.401 , pp. 290-293
    • Scita, G.1    Nordstrom, J.2    Carbone, R.3
  • 49
    • 0031829163 scopus 로고    scopus 로고
    • Activation of both MAP kinase and phosphatidylinositide 3-kinase by ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly
    • Potempa S, Ridley AJ. Activation of both MAP kinase and phosphatidylinositide 3-kinase by ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly. Mol Biol Cell 1998, 9, 2185-2200.
    • (1998) Mol Biol Cell , vol.9 , pp. 2185-2200
    • Potempa, S.1    Ridley, A.J.2


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