-
1
-
-
0003799070
-
-
CSHL Press, Cold Spring Harbor, NY
-
Hogan BB, R, Constantini F. and Lacey E.: Manipulating the Mouse Embryo: A Laboratory Manual. CSHL Press, Cold Spring Harbor, NY, 1994.
-
(1994)
Manipulating the Mouse Embryo: A Laboratory Manual
-
-
Hogan, B.B.R.1
Constantini, F.2
Lacey, E.3
-
2
-
-
0027520318
-
Production of transgenic mice
-
Gordon JW. Production of transgenic mice. Methods Enzymol 1993; 225:747-771.
-
(1993)
Methods Enzymol
, vol.225
, pp. 747-771
-
-
Gordon, J.W.1
-
3
-
-
0019828904
-
Mechanisms and applications of DNA-mediated gene transfer in mammalian cells-a review
-
Scangos G, Ruddle FH. Mechanisms and applications of DNA-mediated gene transfer in mammalian cells-a review. Gene 1981; 14:1-10.
-
(1981)
Gene
, vol.14
, pp. 1-10
-
-
Scangos, G.1
Ruddle, F.H.2
-
4
-
-
2642522640
-
Genetic transformation of mouse embryos by microinjection of purified DNA
-
Gordon JW, Scangos GA, Plotkin DJ, Barbosa JA, Ruddle FH: Genetic transformation of mouse embryos by microinjection of purified DNA. Proc Natl Acad Sci USA 1980; 77:7380-7384.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 7380-7384
-
-
Gordon, J.W.1
Scangos, G.A.2
Plotkin, D.J.3
Barbosa, J.A.4
Ruddle, F.H.5
-
5
-
-
0019847283
-
Integration and stable germ line transmission of genes injected into mouse pronuclei
-
Gordon JW, Ruddle FH. Integration and stable germ line transmission of genes injected into mouse pronuclei. Science 1981; 214:1244-1246.
-
(1981)
Science
, vol.214
, pp. 1244-1246
-
-
Gordon, J.W.1
Ruddle, F.H.2
-
6
-
-
0023630807
-
Targetted correction of a mutant HPRT gene in mouse embryonic stem cells
-
Doetschman T, Gregg RG, Maeda N, Hooper ML, Melton DW, Thompson S, Smithies O. Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature 1987; 330:576-578.
-
(1987)
Nature
, vol.330
, pp. 576-578
-
-
Doetschman, T.1
Gregg, R.G.2
Maeda, N.3
Hooper, M.L.4
Melton, D.W.5
Thompson, S.6
Smithies, O.7
-
7
-
-
0023646810
-
Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
-
Thomas KR, Capecchi MR. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 1987; 51:503-512.
-
(1987)
Cell
, vol.51
, pp. 503-512
-
-
Thomas, K.R.1
Capecchi, M.R.2
-
8
-
-
0024473608
-
Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells
-
Schwartzberg PL, Goff SP, Robertson EJ. Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells. Science 1989; 246:799-803.
-
(1989)
Science
, vol.246
, pp. 799-803
-
-
Schwartzberg, P.L.1
Goff, S.P.2
Robertson, E.J.3
-
9
-
-
0024420342
-
Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells
-
Zijlstra M, Li E, Sajjadi F, Subramani S, Jaenisch R. Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells. Nature 1989; 342:435-438.
-
(1989)
Nature
, vol.342
, pp. 435-438
-
-
Zijlstra, M.1
Li, E.2
Sajjadi, F.3
Subramani, S.4
Jaenisch, R.5
-
10
-
-
0342449328
-
Ten years of gene targeting: Targeted mouse mutants, from vector design to phenotype analysis
-
Muller U. Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis. Mech Dev 1999; 82:3-21.
-
(1999)
Mech Dev
, vol.82
, pp. 3-21
-
-
Muller, U.1
-
11
-
-
0031044215
-
Viable offspring derived from fetal and adult mammalian cells [see comments]. [Published erratum appears in Nature 1997 Mar 13;386(6621):200.]
-
Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH. Viable offspring derived from fetal and adult mammalian cells [see comments]. [Published erratum appears in Nature 1997 Mar 13;386(6621):200.] Nature 1997; 385:810-813.
-
(1997)
Nature
, vol.385
, pp. 810-813
-
-
Wilmut, I.1
Schnieke, A.E.2
McWhir, J.3
Kind, A.J.4
Campbell, K.H.5
-
12
-
-
0029967424
-
Sheep cloned by nuclear transfer from a cultured cell line [see comments]
-
Campbell KH, McWhir J, Ritchie WA, Wilmut I. Sheep cloned by nuclear transfer from a cultured cell line [see comments]. Nature 1996; 380:64-66.
-
(1996)
Nature
, vol.380
, pp. 64-66
-
-
Campbell, K.H.1
McWhir, J.2
Ritchie, W.A.3
Wilmut, I.4
-
13
-
-
0033576657
-
The future of cloning [news]
-
Gurdon JB, Colman A. The future of cloning [news]. Nature 1999; 402:743-746.
-
(1999)
Nature
, vol.402
, pp. 743-746
-
-
Gurdon, J.B.1
Colman, A.2
-
15
-
-
0242568295
-
Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus
-
Jaenisch R. Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus. Proc Natl Acad Sci USA 1976; 73:1260-1264.
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, pp. 1260-1264
-
-
Jaenisch, R.1
-
16
-
-
0344292575
-
Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection
-
Jahner D, Haase K, Mulligan R, Jaenisch R. Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection. Proc Natl Acad Sci USA 1985; 82:6927-6931.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 6927-6931
-
-
Jahner, D.1
Haase, K.2
Mulligan, R.3
Jaenisch, R.4
-
17
-
-
0020582124
-
Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus
-
Mann R, Mulligan RC, Baltimore D. Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell 1983; 33:153-159.
-
(1983)
Cell
, vol.33
, pp. 153-159
-
-
Mann, R.1
Mulligan, R.C.2
Baltimore, D.3
-
18
-
-
0010498843
-
Efficient insertion of genes into the mouse germ line via retroviral vectors
-
van der Putten H, Botteri FM, Miller AD, Rosenfeld MG, Fan H, Evans RM, Verma IM. Efficient insertion of genes into the mouse germ line via retroviral vectors. Proc Natl Acad Sci USA 1985; 82:6148-6152.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 6148-6152
-
-
Van Der Putten, H.1
Botteri, F.M.2
Miller, A.D.3
Rosenfeld, M.G.4
Fan, H.5
Evans, R.M.6
Verma, I.M.7
-
20
-
-
0031794149
-
Transposition of the Drosophila element mariner into the chicken germ line [see comments]. [Published erratum appears in Nat Biotechnol 1999 Jan;17(1):81.]
-
Sherman A, Dawson A, Mather C, Gilhooley H, Li Y, Mitchell R, Finnegan D, Sang H. Transposition of the Drosophila element mariner into the chicken germ line [see comments]. [Published erratum appears in Nat Biotechnol 1999 Jan;17(1):81.] Nat Biotechnol 1998; 16:1050-1053.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 1050-1053
-
-
Sherman, A.1
Dawson, A.2
Mather, C.3
Gilhooley, H.4
Li, Y.5
Mitchell, R.6
Finnegan, D.7
Sang, H.8
-
21
-
-
0031566158
-
Comparison of three nonviral transfection methods for foreign gene expression in early chicken embryos in ovo
-
Muramatsu T, Mizutani Y, Ohmori Y, Okumura J. Comparison of three nonviral transfection methods for foreign gene expression in early chicken embryos in ovo. Biochem Biophys Res Commun 1997; 230:376-380.
-
(1997)
Biochem Biophys Res Commun
, vol.230
, pp. 376-380
-
-
Muramatsu, T.1
Mizutani, Y.2
Ohmori, Y.3
Okumura, J.4
-
22
-
-
0040914505
-
‘Shocking’ developments in chick embryology: Electroporation and in ovo gene expression
-
Itasaki N, Bel-Vialar S, Krumlauf R. ‘Shocking’ developments in chick embryology:electroporation and in ovo gene expression. Nat Cell Biol 1999; 1:E203-E207.
-
(1999)
Nat Cell Biol
, vol.1
, pp. E203-E207
-
-
Itasaki, N.1
Bel-Vialar, S.2
Krumlauf, R.3
-
23
-
-
0029786931
-
Single- copy transgenic mice with chosen-site integration [See comments]
-
Bronson SK, Plaehn EG, Kluckman KD, Hagaman JR, Maeda N, Smithies O. Single- copy transgenic mice with chosen-site integration [See comments]. Proc Natl Acad Sci USA 1996; 93:9067-9072.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9067-9072
-
-
Bronson, S.K.1
Plaehn, E.G.2
Kluckman, K.D.3
Hagaman, J.R.4
Maeda, N.5
Smithies, O.6
-
24
-
-
0032322845
-
Mouse gene trap approach: Identification of novel genes and characterization of their biological functions
-
Kitajima K, Takeuchi T. Mouse gene trap approach: identification of novel genes and characterization of their biological functions. Biochem Cell Biol 1998; 76:1029-1037.
-
(1998)
Biochem Cell Biol
, vol.76
, pp. 1029-1037
-
-
Kitajima, K.1
Takeuchi, T.2
-
25
-
-
0031796893
-
Comprehensive mammalian genetics: History and future prospects of gene trapping in the mouse
-
Zambrowicz BP, Friedrich GA. Comprehensive mammalian genetics: history and future prospects of gene trapping in the mouse. Int J Dev Biol 1998; 42:1025-1036.
-
(1998)
Int J Dev Biol
, vol.42
, pp. 1025-1036
-
-
Zambrowicz, B.P.1
Friedrich, G.A.2
-
27
-
-
0032993431
-
Cloning of male mice from adult tail-tip cells [news]
-
Wakayama T, Yanagimachi R. Cloning of male mice from adult tail-tip cells [news]. Nat Genet 1999; 22:127-128.
-
(1999)
Nat Genet
, vol.22
, pp. 127-128
-
-
Wakayama, T.1
Yanagimachi, R.2
-
28
-
-
0033592923
-
Mice cloned from embryonic stem cells
-
Wakayama T, Rodriguez I, Perry AC, Yanagimachi R, Mombaerts P. Mice cloned from embryonic stem cells. Proc Natl Acad Sci USA 1999; 96:14984-14989.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14984-14989
-
-
Wakayama, T.1
Rodriguez, I.2
Perry, A.C.3
Yanagimachi, R.4
Mombaerts, P.5
-
29
-
-
0033975060
-
Generation of mice from wild-type and targeted ES cells by nuclear cloning
-
Rideout WM, 3rd, Wakayama T, Wutz A, Eggan K, Jackson-Grusby L, Dausman J, Yanagimachi R, Jaenisch R. Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nat Genet 2000; 24:109-110.
-
(2000)
Nat Genet
, vol.24
, pp. 109-110
-
-
Rideout, W.M.1
Wakayama, T.2
Wutz, A.3
Eggan, K.4
Jackson-Grusby, L.5
Dausman, J.6
Yanagimachi, R.7
Jaenisch, R.8
-
30
-
-
0032560827
-
Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei [see comments]
-
Wakayama T, Perry AC, Zuccotti M, Johnson KR, Yanagimachi R. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei [see comments]. Nature 1998; 394:369-374.
-
(1998)
Nature
, vol.394
, pp. 369-374
-
-
Wakayama, T.1
Perry, A.C.2
Zuccotti, M.3
Johnson, K.R.4
Yanagimachi, R.5
-
31
-
-
0033553592
-
Mammalian transgenesis by intracytoplasmic sperm injection [see comments]
-
Perry AC, Wakayama T, Kishikawa H, Kasai T, Okabe M, Toyoda Y, Yanagimachi R. Mammalian transgenesis by intracytoplasmic sperm injection [see comments]. Science 1999; 284:1180-1183.
-
(1999)
Science
, vol.284
, pp. 1180-1183
-
-
Perry, A.C.1
Wakayama, T.2
Kishikawa, H.3
Kasai, T.4
Okabe, M.5
Toyoda, Y.6
Yanagimachi, R.7
-
32
-
-
0024320352
-
Sperm cells as vectors for introducing foreign DNA into eggs: Genetic transformation of mice [see comments]
-
Lavitrano M, Camaioni A, Fazio VM, Dolci S, Farace MG, Spadafora C. Sperm cells as vectors for introducing foreign DNA into eggs: genetic transformation of mice [see comments]. Cell 1989; 57:717-723.
-
(1989)
Cell
, vol.57
, pp. 717-723
-
-
Lavitrano, M.1
Camaioni, A.2
Fazio, V.M.3
Dolci, S.4
Farace, M.G.5
Spadafora, C.6
-
34
-
-
0026489684
-
Altering the boundaries of Hox3.1 expression: Evidence for antipodal gene regulation
-
Pollock RA, Jay G, Bieberich CJ. Altering the boundaries of Hox3.1 expression:evidence for antipodal gene regulation. Cell 1992; 71:911-923.
-
(1992)
Cell
, vol.71
, pp. 911-923
-
-
Pollock, R.A.1
Jay, G.2
Bieberich, C.J.3
-
36
-
-
0033601096
-
Putting boundaries on silence
-
Sun FL, Elgin SC. Putting boundaries on silence. Cell 1999; 99:459-462.
-
(1999)
Cell
, vol.99
, pp. 459-462
-
-
Sun, F.L.1
Elgin, S.C.2
-
37
-
-
0033615636
-
A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin
-
Francastel C, Walters MC, Groudine M, Martin DI. A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin. Cell 1999; 99:259-269.
-
(1999)
Cell
, vol.99
, pp. 259-269
-
-
Francastel, C.1
Walters, M.C.2
Groudine, M.3
Martin, D.I.4
-
38
-
-
0033118342
-
Nuclear compartments and gene regulation
-
Cockell M, Gasser SM. Nuclear compartments and gene regulation. Curr Opin Genet Dev 1999; 9:199-205.
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 199-205
-
-
Cockell, M.1
Gasser, S.M.2
-
39
-
-
0023663887
-
Position-independent, highlevel expression of the human beta-globin gene in transgenic mice
-
Grosveld F, van Assendelft GB, Greaves DR, Kollias G. Position-independent, highlevel expression of the human beta-globin gene in transgenic mice. Cell 1987; 51:975-985.
-
(1987)
Cell
, vol.51
, pp. 975-985
-
-
Grosveld, F.1
van Assendelft, G.B.2
Greaves, D.R.3
Kollias, G.4
-
40
-
-
0033391288
-
Far upstream regulatory elements enhance position-independent and uterus-specific expression of the murine alpha1(I) collagen promoter in transgenic mice
-
Krempen K, Grotkopp D, Hall K, Bache A, Gillan A, Rippe RA, Brenner DA, Breindl M. Far upstream regulatory elements enhance position-independent and uterus-specific expression of the murine alpha1(I) collagen promoter in transgenic mice. Gene Expr 1999; 8:151-163.
-
(1999)
Gene Expr
, vol.8
, pp. 151-163
-
-
Krempen, K.1
Grotkopp, D.2
Hall, K.3
Bache, A.4
Gillan, A.5
Rippe, R.A.6
Brenner, D.A.7
Breindl, M.8
-
41
-
-
0024536789
-
The beta-globin dominant control region activates homologous and heterologous promoters in a tissue- specific manner
-
Blom van Assendelft G, Hanscombe O, Grosveld F, Greaves DR. The beta-globin dominant control region activates homologous and heterologous promoters in a tissue- specific manner. Cell 1989; 56:969-977.
-
(1989)
Cell
, vol.56
, pp. 969-977
-
-
Blom van Assendelft, G.1
Hanscombe, O.2
Grosveld, F.3
Greaves, D.R.4
-
42
-
-
0033544935
-
Pit-1 binding sites at the somatotrope- specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation
-
Shewchuk BM, Asa SL, Cooke NE, Liebhaber SA. Pit-1 binding sites at the somatotrope- specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation. J Biol Chem 1999; 274:35725-35733.
-
(1999)
J Biol Chem
, vol.274
, pp. 35725-35733
-
-
Shewchuk, B.M.1
Asa, S.L.2
Cooke, N.E.3
Liebhaber, S.A.4
-
43
-
-
0028217613
-
The 5'.flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice
-
Talbot D, Descombes P, Schibler U. The 5'.flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice. Nucleic Acids Res 1994; 22:756-766.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 756-766
-
-
Talbot, D.1
Descombes, P.2
Schibler, U.3
-
44
-
-
0033958481
-
An Alu element from the K18 gene confers position-independent expression in transgenic mice
-
Willoughby DA, Vilalta A, Oshima RG. An Alu element from the K18 gene confers position-independent expression in transgenic mice. J Biol Chem 2000; 275:759-768.
-
(2000)
J Biol Chem
, vol.275
, pp. 759-768
-
-
Willoughby, D.A.1
Vilalta, A.2
Oshima, R.G.3
-
45
-
-
0031717379
-
Inducible gene targeting in mice using the Cre/lox system
-
Sauer B. Inducible gene targeting in mice using the Cre/lox system. Methods 1998; 14:381-392.
-
(1998)
Methods
, vol.14
, pp. 381-392
-
-
Sauer, B.1
-
46
-
-
0032569968
-
Recombinogenic targeting: A new approach to genomic analysis-a review
-
Shashikant CS, Carr JL, Bhargava J, Bentley KL, Ruddle FH. Recombinogenic targeting:a new approach to genomic analysis-a review. Gene 1998; 223:9-20.
-
(1998)
Gene
, vol.223
, pp. 9-20
-
-
Shashikant, C.S.1
Carr, J.L.2
Bhargava, J.3
Bentley, K.L.4
Ruddle, F.H.5
-
47
-
-
0023349389
-
Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors
-
Burke DT, Carle GF, Olson MV. Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors. Science 1987; 236:806-812.
-
(1987)
Science
, vol.236
, pp. 806-812
-
-
Burke, D.T.1
Carle, G.F.2
Olson, M.V.3
-
48
-
-
0028318417
-
A new bacteriophage P1-derived vector for the propagation of large human DNA fragments
-
Ioannou PA, Amemiya CT, Garnes J, Kroisel PM, Shizuya H, Chen C, Batzer MA, de Jong PJ. A new bacteriophage P1-derived vector for the propagation of large human DNA fragments. Nat Genet 1994; 6:84-89.
-
(1994)
Nat Genet
, vol.6
, pp. 84-89
-
-
Ioannou, P.A.1
Amemiya, C.T.2
Garnes, J.3
Kroisel, P.M.4
Shizuya, H.5
Chen, C.6
Batzer, M.A.7
de Jong, P.J.8
-
49
-
-
0026518431
-
Cloning high molecular weight DNA fragments by the bacteriophage P1 system
-
Sternberg NL. Cloning high molecular weight DNA fragments by the bacteriophage P1 system. Trends Genet 1992; 8:11-16.
-
(1992)
Trends Genet
, vol.8
, pp. 11-16
-
-
Sternberg, N.L.1
-
50
-
-
0026703169
-
Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector
-
Shizuya H, Birren B, Kim UJ, Mancino V, Slepak T, Tachiiri Y, Simon M. Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector. Proc Natl Acad Sci USA 1992; 89:8794-8797.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 8794-8797
-
-
Shizuya, H.1
Birren, B.2
Kim, U.J.3
Mancino, V.4
Slepak, T.5
Tachiiri, Y.6
Simon, M.7
-
51
-
-
0028874707
-
A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes
-
Bradshaw MS, Bollekens JA, Ruddle FH. A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes. Nucleic Acids Res 1995; 23:4850-4856.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 4850-4856
-
-
Bradshaw, M.S.1
Bollekens, J.A.2
Ruddle, F.H.3
-
52
-
-
0029063916
-
YAC transgenics and the study of genetics and human disease
-
Lamb BT, Gearhart JD. YAC transgenics and the study of genetics and human disease. Curr Opin Genet Dev 1995; 5:342-348.
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 342-348
-
-
Lamb, B.T.1
Gearhart, J.D.2
-
54
-
-
0030930989
-
Gene replacement with linear DNA fragments in wild-type Escherichia coli: Enhancement by Chi sites
-
Dabert P, Smith GR. Gene replacement with linear DNA fragments in wild-type Escherichia coli: enhancement by Chi sites. Genetics 1997; 145:877-889.
-
(1997)
Genetics
, vol.145
, pp. 877-889
-
-
Dabert, P.1
Smith, G.R.2
-
55
-
-
0032574847
-
Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis
-
Jessen JR, Meng A, McFarlane RJ, Paw BH, Zon LI, Smith GR, Lin S. Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis. Proc Natl Acad Sci USA 1998; 95:5121-5126.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5121-5126
-
-
Jessen, J.R.1
Meng, A.2
McFarlane, R.J.3
Paw, B.H.4
Zon, L.I.5
Smith, G.R.6
Lin, S.7
-
56
-
-
0030842624
-
Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome [see comments]
-
Yang XW, Model P, Heintz N. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome [see comments]. Nat Biotechnol 1997; 15:859-865.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 859-865
-
-
Yang, X.W.1
Model, P.2
Heintz, N.3
-
57
-
-
0028427907
-
Reporter genes in transgenic mice
-
Cui C, Wani MA, Wight D, Kopchick J, Stambrook PJ. Reporter genes in transgenic mice. Transgenic Res 1994; 3:182-194.
-
(1994)
Transgenic Res
, vol.3
, pp. 182-194
-
-
Cui, C.1
Wani, M.A.2
Wight, D.3
Kopchick, J.4
Stambrook, P.J.5
-
58
-
-
0032611734
-
Reporter genes for the study of transcriptional regulation in transgenic mouse embryos
-
Gilthorpe JD, Rigby PW. Reporter genes for the study of transcriptional regulation in transgenic mouse embryos. Methods Mol Biol 1999; 97:159-182.
-
(1999)
Methods Mol Biol
, vol.97
, pp. 159-182
-
-
Gilthorpe, J.D.1
Rigby, P.W.2
-
59
-
-
0032560580
-
‘Green mice’ and their potential usage in biological research
-
Ikawa M, Yamada S, Nakanishi T, Okabe M. ‘Green mice’ and their potential usage in biological research. FEBS Lett 1998; 430:83-87.
-
(1998)
FEBS Lett
, vol.430
, pp. 83-87
-
-
Ikawa, M.1
Yamada, S.2
Nakanishi, T.3
Okabe, M.4
-
60
-
-
0030698846
-
Dicistronic LacZ and alkaline phosphatase reporter constructs permit simultaneous histological analysis of expression from multiple transgenes
-
880, 882
-
Li X, Wang W, Lufkin T. Dicistronic LacZ and alkaline phosphatase reporter constructs permit simultaneous histological analysis of expression from multiple transgenes. Biotechniques 1997; 23:874-878, 880, 882.
-
(1997)
Biotechniques
, vol.23
, pp. 874-878
-
-
Li, X.1
Wang, W.2
Lufkin, T.3
-
61
-
-
0024584093
-
Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice
-
Kothary R, Clapoff S, Darling S, Perry MD, Moran LA, Rossant J. Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice. Development 1989; 105:707-714.
-
(1989)
Development
, vol.105
, pp. 707-714
-
-
Kothary, R.1
Clapoff, S.2
Darling, S.3
Perry, M.D.4
Moran, L.A.5
Rossant, J.6
-
62
-
-
0029911791
-
A long-range regulatory element of Hoxc8 identified by using the pClasper vector
-
Bradshaw MS, Shashikant CS, Belting HG, Bollekens JA, Ruddle FH. A long-range regulatory element of Hoxc8 identified by using the pClasper vector. Proc Natl Acad Sci USA 1996; 93:2426-2430.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2426-2430
-
-
Bradshaw, M.S.1
Shashikant, C.S.2
Belting, H.G.3
Bollekens, J.A.4
Ruddle, F.H.5
-
63
-
-
0031962457
-
Molecular evolution of Hox gene regulation: Cloning and transgenic analysis of the lamprey HoxQ8 gene
-
Carr JL, Shashikant CS, Bailey WJ, Ruddle FH. Molecular evolution of Hox gene regulation: cloning and transgenic analysis of the lamprey HoxQ8 gene. J Exp Zool 1998; 280:73-85.
-
(1998)
J Exp Zool
, vol.280
, pp. 73-85
-
-
Carr, J.L.1
Shashikant, C.S.2
Bailey, W.J.3
Ruddle, F.H.4
-
64
-
-
0033963666
-
A recombinogenic targeting method to modify large-inserts for cis-regulatory analysis in transgenic mice: Construction and expression of a 100-kb, zebrafish Hoxa-11b-lacZ reporter gene
-
Chiu CH, Amemiya CT, Carr JL, Bhargava J, Hwang JK, Shashikant CS, Ruddle FH, Wagner GP. A recombinogenic targeting method to modify large-inserts for cis-regulatory analysis in transgenic mice: construction and expression of a 100-kb, zebrafish Hoxa-11b-lacZ reporter gene. Dev Genes Evol 2000; 210:105-109.
-
(2000)
Dev Genes Evol
, vol.210
, pp. 105-109
-
-
Chiu, C.H.1
Amemiya, C.T.2
Carr, J.L.3
Bhargava, J.4
Hwang, J.K.5
Shashikant, C.S.6
Ruddle, F.H.7
Wagner, G.P.8
-
65
-
-
0028804573
-
Construction of a genomic DNA ‘feature map’ by sequencing from nested deletions: Application to the HLA class I region
-
Krishnan BR, Jamry I, Berg DE, Berg CM, Chaplin DD. Construction of a genomic DNA ‘feature map’ by sequencing from nested deletions: application to the HLA class I region. Nucleic Acids Res 1995; 23:117-122.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 117-122
-
-
Krishnan, B.R.1
Jamry, I.2
Berg, D.E.3
Berg, C.M.4
Chaplin, D.D.5
-
66
-
-
0028842823
-
Restriction map of a 35-kb HLA fragment constructed by nested deletion ‘drop-out’ mapping
-
LaBanca F, Krishnan BR, Chaplin DD, Berg DE, Berg CM. Restriction map of a 35-kb HLA fragment constructed by nested deletion ‘drop-out’ mapping. Gene 1995; 164:335-339.
-
(1995)
Gene
, vol.164
, pp. 335-339
-
-
LaBanca, F.1
Krishnan, B.R.2
Chaplin, D.D.3
Berg, D.E.4
Berg, C.M.5
-
67
-
-
0030915187
-
Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome [see comments]
-
Smith DJ, Stevens ME, Sudanagunta SP, Bronson RT, Makhinson M, Watabe AM, O’Dell TJ, Fung J, Weier HU, Cheng JF, Rubin EM. Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome [see comments]. Nat Genet 1997; 16:28-36.
-
(1997)
Nat Genet
, vol.16
, pp. 28-36
-
-
Smith, D.J.1
Stevens, M.E.2
Sudanagunta, S.P.3
Bronson, R.T.4
Makhinson, M.5
Watabe, A.M.6
O’Dell, T.J.7
Fung, J.8
Weier, H.U.9
Cheng, J.F.10
Rubin, E.M.11
-
68
-
-
0032775932
-
BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin [see comments]
-
Yang XW, Wynder C, Doughty ML, Heintz N. BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin [see comments]. Nat Genet 1999; 22:327-335.
-
(1999)
Nat Genet
, vol.22
, pp. 327-335
-
-
Yang, X.W.1
Wynder, C.2
Doughty, M.L.3
Heintz, N.4
-
69
-
-
0032799479
-
Gene dosage in mice-BAC to the future [news; comment]
-
Magdaleno SM, Curran T. Gene dosage in mice-BAC to the future [news; comment]. Nat Genet 1999; 22:319-320.
-
(1999)
Nat Genet
, vol.22
, pp. 319-320
-
-
Magdaleno, S.M.1
Curran, T.2
-
70
-
-
18844476167
-
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue
-
Antoch MP, Song EJ, Chang AM, Vitaterna MH, Zhao Y, Wilsbacher LD, Sangoram AM, King DP, Pinto LH, Takahashi JS. Functional identification of the mouse circadian Clock gene by transgenic BAC rescue. Cell 1997; 89:655-667.
-
(1997)
Cell
, vol.89
, pp. 655-667
-
-
Antoch, M.P.1
Song, E.J.2
Chang, A.M.3
Vitaterna, M.H.4
Zhao, Y.5
Wilsbacher, L.D.6
Sangoram, A.M.7
King, D.P.8
Pinto, L.H.9
Takahashi, J.S.10
-
71
-
-
0029836349
-
Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice
-
Turki J, Lorenz JN, Green SA, Donnelly ET, Jacinto M, Liggett SB. Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice. Proc Natl Acad Sci USA 1996; 93:10483-10488.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10483-10488
-
-
Turki, J.1
Lorenz, J.N.2
Green, S.A.3
Donnelly, E.T.4
Jacinto, M.5
Liggett, S.B.6
-
72
-
-
0342437532
-
Production of human antibody repertoires in transgenic mice
-
Bruggemann M, Taussig MJ. Production of human antibody repertoires in transgenic mice. Curr Opin Biotechnol 1997; 8:455-458.
-
(1997)
Curr Opin Biotechnol
, vol.8
, pp. 455-458
-
-
Bruggemann, M.1
Taussig, M.J.2
-
73
-
-
0032715903
-
Antibody repertoires of four- and five-feature translocus mice carrying human immunoglobulin heavy chain and kappa and lambda light chain yeast artificial chromosomes
-
Nicholson IC, Zou X, Popov AV, Cook GP, Corps EM, Humphries S, Ayling C, Goyenechea B, Xian J, Taussig MJ, Neuberger MS, Bruggemann M. Antibody repertoires of four- and five-feature translocus mice carrying human immunoglobulin heavy chain and kappa and lambda light chain yeast artificial chromosomes. J Immunol 1999; 163:6898-6906.
-
(1999)
J Immunol
, vol.163
, pp. 6898-6906
-
-
Nicholson, I.C.1
Zou, X.2
Popov, A.V.3
Cook, G.P.4
Corps, E.M.5
Humphries, S.6
Ayling, C.7
Goyenechea, B.8
Xian, J.9
Taussig, M.J.10
Neuberger, M.S.11
Bruggemann, M.12
-
74
-
-
0031898727
-
Inducible gene expression in the nervous system of transgenic mice
-
Gingrich JR, Roder J. Inducible gene expression in the nervous system of transgenic mice. Annu Rev Neurosci 1998; 21:377-405.
-
(1998)
Annu Rev Neurosci
, vol.21
, pp. 377-405
-
-
Gingrich, J.R.1
Roder, J.2
-
75
-
-
0030681310
-
Inducible gene expression in mammalian cells and transgenic mice
-
Saez E, No D, West A, Evans RM. Inducible gene expression in mammalian cells and transgenic mice. Curr Opin Biotechnol 1997; 8:608-616.
-
(1997)
Curr Opin Biotechnol
, vol.8
, pp. 608-616
-
-
Saez, E.1
No, D.2
West, A.3
Evans, R.M.4
-
76
-
-
0020470466
-
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes
-
Palmiter RD, Brinster RL, Hammer RE, Trumbauer ME, Rosenfeld MG, Birnberg NC, Evans RM. Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature 1982; 300:611-615.
-
(1982)
Nature
, vol.300
, pp. 611-615
-
-
Palmiter, R.D.1
Brinster, R.L.2
Hammer, R.E.3
Trumbauer, M.E.4
Rosenfeld, M.G.5
Birnberg, N.C.6
Evans, R.M.7
-
77
-
-
0025369703
-
Transgenic mice with intracellular immunity to influenza virus
-
Arnheiter H, Skuntz S, Noteborn M, Chang S, Meier E. Transgenic mice with intracellular immunity to influenza virus. Cell 1990; 62:51-61.
-
(1990)
Cell
, vol.62
, pp. 51-61
-
-
Arnheiter, H.1
Skuntz, S.2
Noteborn, M.3
Chang, S.4
Meier, E.5
-
78
-
-
0029767838
-
Ligand-activated site-specific recombination in mice
-
Feil R, Brocard J, Mascrez B, LeMeur M, Metzger D, Chambon P. Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci USA 1996; 93:10887-10890.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10887-10890
-
-
Feil, R.1
Brocard, J.2
Mascrez, B.3
LeMeur, M.4
Metzger, D.5
Chambon, P.6
-
79
-
-
0029962975
-
Inducible site-directed recombination in mouse embryonic stem cells
-
Zhang Y, Riesterer C, Ayrall AM, Sablitzky F, Littlewood TD, Reth M. Inducible site-directed recombination in mouse embryonic stem cells. Nucleic Acids Res 1996; 24:543-548.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 543-548
-
-
Zhang, Y.1
Riesterer, C.2
Ayrall, A.M.3
Sablitzky, F.4
Littlewood, T.D.5
Reth, M.6
-
80
-
-
0029865151
-
Ecdysone-inducible gene expression in mammalian cells and transgenic mice
-
No D, Yao TP, Evans RM. Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc Natl Acad Sci USA 1996; 93:3346-3351.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3346-3351
-
-
No, D.1
Yao, T.P.2
Evans, R.M.3
-
81
-
-
0027741191
-
Functional ecdysone receptor is the product of EcR and Ultraspiracle genes
-
Yao TP, Forman BM, Jiang Z, Cherbas L, Chen JD, McKeown M, Cherbas P, Evans RM. Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. Nature 1993; 366:476-479.
-
(1993)
Nature
, vol.366
, pp. 476-479
-
-
Yao, T.P.1
Forman, B.M.2
Jiang, Z.3
Cherbas, L.4
Chen, J.D.5
McKeown, M.6
Cherbas, P.7
Evans, R.M.8
-
82
-
-
0024358496
-
Multiplex gene regulation: A two-tiered approach to transgene regulation in transgenic mice
-
Byrne GW, Ruddle FH. Multiplex gene regulation: a two-tiered approach to transgene regulation in transgenic mice. Proc Natl Acad Sci USA 1989; 86:5473-5477.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5473-5477
-
-
Byrne, G.W.1
Ruddle, F.H.2
-
83
-
-
0032543986
-
Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8
-
Yueh YG, Gardner DP, Kappen C. Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8. Proc Natl Acad Sci USA 1998; 95:9956-9961.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9956-9961
-
-
Yueh, Y.G.1
Gardner, D.P.2
Kappen, C.3
-
84
-
-
0033570359
-
Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells
-
Rowitch DH, B S-J, Lee SM, Flax JD, Snyder EY, McMahon AP. Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci 1999; 19:8954-8965.
-
(1999)
J Neurosci
, vol.19
, pp. 8954-8965
-
-
Rowitch, D.H.B.S.-J.1
Lee, S.M.2
Flax, J.D.3
Snyder, E.Y.4
McMahon, A.P.5
-
85
-
-
0026078836
-
Binary system for regulating transgene expression in mice: Targeting int-2 gene expression with yeast GAL4/UAS control elements
-
Ornitz DM, Moreadith RW, Leder P. Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements. Proc Natl Acad Sci USA 1991; 88:698-702.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 698-702
-
-
Ornitz, D.M.1
Moreadith, R.W.2
Leder, P.3
-
86
-
-
0023239517
-
Functional inactivation of genes by dominant negative mutations
-
Herskowitz I. Functional inactivation of genes by dominant negative mutations. Nature 1987; 329:219-222.
-
(1987)
Nature
, vol.329
, pp. 219-222
-
-
Herskowitz, I.1
-
87
-
-
0029976805
-
The use of dominant-negative mutations to elucidate signal transduction pathways in lymphocytes
-
Perlmutter RM, Alberola-Ila J. The use of dominant-negative mutations to elucidate signal transduction pathways in lymphocytes. Curr Opin Immunol 1996; 8:285-290.
-
(1996)
Curr Opin Immunol
, vol.8
, pp. 285-290
-
-
Perlmutter, R.M.1
Alberola-Ila, J.2
-
88
-
-
0033371809
-
Dominant negative mutants of guanylyl cyclase: Probes for global functions and intramolecular mechanisms
-
Yuen PS. Dominant negative mutants of guanylyl cyclase: probes for global functions and intramolecular mechanisms. Methods 1999; 19:532-544.
-
(1999)
Methods
, vol.19
, pp. 532-544
-
-
Yuen, P.S.1
-
89
-
-
0032845626
-
Antisense transgenics in animals
-
Erickson RP. Antisense transgenics in animals. Methods 1999; 18:304-310.
-
(1999)
Methods
, vol.18
, pp. 304-310
-
-
Erickson, R.P.1
-
90
-
-
0032192170
-
Expression of ribozymes in gene transfer systems to modulate target RNA levels
-
Welch PJ, Barber JR, Wong-Staal F. Expression of ribozymes in gene transfer systems to modulate target RNA levels. Curr Opin Biotechnol 1998; 9:486-496.
-
(1998)
Curr Opin Biotechnol
, vol.9
, pp. 486-496
-
-
Welch, P.J.1
Barber, J.R.2
Wong-Staal, F.3
-
91
-
-
0030002133
-
Efficient and specific ribozyme-mediated reduction of bovine alpha-lactalbumin expression in double transgenic mice
-
L’Huillier PJ, Soulier S, Stinnakre MG, Lepourry L, Davis SR, Mercier JC, Vilotte JL. Efficient and specific ribozyme-mediated reduction of bovine alpha-lactalbumin expression in double transgenic mice. Proc Natl Acad Sci USA 1996; 93:6698-6703.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6698-6703
-
-
L’Huillier, P.J.1
Soulier, S.2
Stinnakre, M.G.3
Lepourry, L.4
Davis, S.R.5
Mercier, J.C.6
Vilotte, J.L.7
-
92
-
-
0032742101
-
Diet-dependent hypercalciuria in transgenic mice with reduced CLC5 chloride channel expression
-
Luyckx VA, Leclercq B, Dowland LK, Yu AS. Diet-dependent hypercalciuria in transgenic mice with reduced CLC5 chloride channel expression. Proc Natl Acad Sci USA 1999; 96:12174-12179.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12174-12179
-
-
Luyckx, V.A.1
Leclercq, B.2
Dowland, L.K.3
Yu, A.S.4
-
93
-
-
0033027061
-
Anti-beta s-ribozyme reduces beta s mRNA levels in transgenic mice: Potential application to the gene therapy of sickle cell anemia
-
Alami R, Gilman JG, Feng YQ, Marmorato A, Rochlin I, Suzuka SM, Fabry ME, Nagel RL, Bouhassira EE. Anti-beta s-ribozyme reduces beta s mRNA levels in transgenic mice: potential application to the gene therapy of sickle cell anemia. Blood Cells Mol Dis 1999; 25:110-119.
-
(1999)
Blood Cells Mol Dis
, vol.25
, pp. 110-119
-
-
Alami, R.1
Gilman, J.G.2
Feng, Y.Q.3
Marmorato, A.4
Rochlin, I.5
Suzuka, S.M.6
Fabry, M.E.7
Nagel, R.L.8
Bouhassira, E.E.9
-
94
-
-
0033607163
-
Dose-response resistance to HIV-1/MuLV pseudotype virus ex vivo in a hairpin ribozyme transgenic mouse model
-
Andang M, Hinkula J, Hotchkiss G, Larsson S, Britton S, Wong-Staal F, Wahren B, Ahrlund-Richter L. Dose-response resistance to HIV-1/MuLV pseudotype virus ex vivo in a hairpin ribozyme transgenic mouse model. Proc Natl Acad Sci USA 1999; 96:12749-12753.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12749-12753
-
-
Andang, M.1
Hinkula, J.2
Hotchkiss, G.3
Larsson, S.4
Britton, S.5
Wong-Staal, F.6
Wahren, B.7
Ahrlund-Richter, L.8
-
95
-
-
0031028759
-
Mouse models of human disease. Part II: Recent progress and future directions
-
Bedell MA, Largaespada DA, Jenkins NA, Copeland NG. Mouse models of human disease. Part II: recent progress and future directions. Genes Dev 1997; 11:11-43.
-
(1997)
Genes Dev
, vol.11
, pp. 11-43
-
-
Bedell, M.A.1
Largaespada, D.A.2
Jenkins, N.A.3
Copeland, N.G.4
-
96
-
-
0031021132
-
Mouse models of human disease. Part I: Techniques and resources for genetic analysis in mice
-
Bedell MA, Jenkins NA, Copeland NG. Mouse models of human disease. Part I:techniques and resources for genetic analysis in mice. Genes Dev 1997; 11:1-10.
-
(1997)
Genes Dev
, vol.11
, pp. 1-10
-
-
Bedell, M.A.1
Jenkins, N.A.2
Copeland, N.G.3
|