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Volumn 17, Issue 1, 2003, Pages 66-91

Retinoids as chemopreventive agents

Author keywords

Cancer; Clinical trials; Precancer; RAR; Retinoids; Rexinoids

Indexed keywords

4 DIMETHYLAMINO 3' METHYLAZOBENZENE; 4 [2 (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 NAPHTHYL) 1,3 DIOXOLAN 2 YL]BENZOIC ACID; 4 [7 ADAMANTYL 6 [(2 METHOXYETHOXY)METHOXY] 2 NAPHTHYL]BENZOIC ACID; 6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; 6 [4 METHOXY 3 (1 METHYLCYCLOHEXYL)PHENYL] 2 NAPHTHOIC ACID; ANTINEOPLASTIC AGENT; BETA CAROTENE; BEXAROTENE; CD 2325; CD 336; CD 3369; CELL SURFACE RECEPTOR; ETRETIN; ETRETINATE; FENRETINIDE; ISOTRETINOIN; LGD 1550; MITOGEN ACTIVATED PROTEIN KINASE; NIK 333; PLACEBO; POLYPRENOIC ACID; PROTEIN KINASE B; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOID; RETINOID X RECEPTOR; RETINOL; RETINOL PALMITATE; TAZAROTENE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 0038147046     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (12)

References (283)
  • 1
    • 0002241474 scopus 로고    scopus 로고
    • Biologic basis of retinoid pharmacology: Implications for cancer prevention and therapy
    • Davies P, Lippman SM. Biologic basis of retinoid pharmacology: implications for cancer prevention and therapy. Adv Oncol 1996; 12: 2-10.
    • (1996) Adv. Oncol. , vol.12 , pp. 2-10
    • Davies, P.1    Lippman, S.M.2
  • 3
    • 0029796637 scopus 로고    scopus 로고
    • Retinoids in cancer chemoprevention
    • Lotan R. Retinoids in cancer chemoprevention. FASEB J 1996; 10: 1031-9.
    • (1996) FASEB J. , vol.10 , pp. 1031-1039
    • Lotan, R.1
  • 4
    • 0033981605 scopus 로고    scopus 로고
    • Advances in the development of retinoids as chemopreventive agents
    • Lippman SM, Lotan R. Advances in the development of retinoids as chemopreventive agents. J Nutr 2000; (Suppl) 130: S479-82.
    • (2000) J. Nutr. , vol.130 , Issue.SUPPL.
    • Lippman, S.M.1    Lotan, R.2
  • 5
    • 0033779590 scopus 로고    scopus 로고
    • The retinoids and cancer prevention mechanisms
    • Dragnev KH, Rigas JR, Dmitrovsky E. The retinoids and cancer prevention mechanisms. Oncologist 2000; 5:361-8.
    • (2000) Oncologist , vol.5 , pp. 361-368
    • Dragnev, K.H.1    Rigas, J.R.2    Dmitrovsky, E.3
  • 6
    • 0035749803 scopus 로고    scopus 로고
    • The promise of retinoids to fight against cancer
    • Altucci L, Gronmneyer H. The promise of retinoids to fight against cancer. Nat Rev Cancer 2001; 1: 181-93.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 181-193
    • Altucci, L.1    Gronemeyer, H.2
  • 8
    • 0017136711 scopus 로고
    • Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids)
    • Sporn MB, Dunlop NM, Newton DL, Smith JM. Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids). Fed Proc 1976; 35: 1332-8.
    • (1976) Fed. Proc. , vol.35 , pp. 1332-1338
    • Sporn, M.B.1    Dunlop, N.M.2    Newton, D.L.3    Smith, J.M.4
  • 9
    • 0019223520 scopus 로고
    • Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells
    • Lotan R. Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells. Biochim Biophys Acta 1980; 605: 33-91.
    • (1980) Biochim. Biophys. Acta , vol.605 , pp. 33-91
    • Lotan, R.1
  • 10
    • 0002020447 scopus 로고
    • Cellular biology and biochemistry of retinoids
    • Sporn MB, Roberts AB, Goodman DS, eds. 2nd ed. New York, NY: Raven Press Ltd
    • Gudas LJ, Sporn MB, Roberts AB. Cellular biology and biochemistry of retinoids. In: Sporn MB, Roberts AB, Goodman DS, eds. The retinoids: biology, chemistry and medicine, 2nd ed. New York, NY: Raven Press Ltd, 1994: 443-520.
    • (1994) The Retinoids: Biology, Chemistry and Medicine , pp. 443-520
    • Gudas, L.J.1    Sporn, M.B.2    Roberts, A.B.3
  • 11
    • 0023804750 scopus 로고
    • Vitamin A analogs (retinoids) as biological response modifiers
    • Lotan R. Vitamin A analogs (retinoids) as biological response modifiers. Prog Clin Biol Res 1988; 259: 261-71.
    • (1988) Prog. Clin. Biol. Res. , vol.259 , pp. 261-271
    • Lotan, R.1
  • 13
    • 0029794132 scopus 로고    scopus 로고
    • A decade of molecular biology of retinoic acid receptors
    • Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J 1996; 10: 940-54.
    • (1996) FASEB J. , vol.10 , pp. 940-954
    • Chambon, P.1
  • 14
    • 0000205466 scopus 로고    scopus 로고
    • The retinoids: Cancer therapy and prevention mechanisms
    • Nau H, Blanner W, eds. Retinoids. The Biochemical and molecular basis of vitamin A and retinoid action. Berlin: Springer
    • Nason-Burchenal K, Dmitrovsky E. The retinoids: cancer therapy and prevention mechanisms. In: Nau H, Blanner W, eds. Retinoids. The Biochemical and molecular basis of vitamin A and retinoid action. Handbook of experimental pharmacology. Berlin: Springer, 1999, 139: 301-22.
    • (1999) Handbook of Experimental Pharmacology , vol.139 , pp. 301-322
    • Nason-Burchenal, K.1    Dmitrovsky, E.2
  • 15
    • 0001319804 scopus 로고
    • Retinoids and human cancer
    • Sporn MB, Roberts AB, Goodman DS, eds. 2nd ed. New York: Raven Press Ltd
    • Hong WK, Itri LM. Retinoids and human cancer. In: Sporn MB, Roberts AB, Goodman DS, eds. The retinoids: biology, chemistry, and medicine, 2nd ed. New York: Raven Press Ltd, 1994, 597-630.
    • (1994) The Retinoids: Biology, Chemistry, and Medicine , pp. 597-630
    • Hong, W.K.1    Itri, L.M.2
  • 17
    • 0000147542 scopus 로고    scopus 로고
    • Recent advances in chemo-prevention of cancer
    • Hong WK, Sporn MB. Recent advances in chemo-prevention of cancer. Science 1997; 278: 1073-7.
    • (1997) Science , vol.278 , pp. 1073-1077
    • Hong, W.K.1    Sporn, M.B.2
  • 19
    • 0022916262 scopus 로고
    • 13-cis-retinoic acid in the treatment of oral leukoplakia
    • Hong WK, Endicott J, Itri LM, et al. 13-cis-retinoic acid in the treatment of oral leukoplakia. N Eng] J Med 1986; 315: 1501-5.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1501-1505
    • Hong, W.K.1    Endicott, J.2    Itri, L.M.3
  • 20
    • 0028343678 scopus 로고
    • Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-transretinoic acid: A randomized trial
    • Meyskens FL Jr, Surwit E, Moon TE, et al. Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-transretinoic acid: a randomized trial. J Natl Cancer Inst 1994; 86: 539-43.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 539-543
    • Meyskens F.L., Jr.1    Surwit, E.2    Moon, T.E.3
  • 22
    • 0025091456 scopus 로고
    • Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck
    • Hong WK, Lippman SM, Itri LM, et al. Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. N Engl J Med 1990; 323: 795-801.
    • (1990) N. Engl. J. Med. , vol.323 , pp. 795-801
    • Hong, W.K.1    Lippman, S.M.2    Itri, L.M.3
  • 23
    • 0027207575 scopus 로고
    • Adjuvant treatment of stage I lung cancer with high-dose vitamin A
    • Pastorino U, Infante M, Maioli M, et al. Adjuvant treatment of stage I lung cancer with high-dose vitamin A. J Clin Oncol 1993; 11: 1216-22.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 1216-1222
    • Pastorino, U.1    Infante, M.2    Maioli, M.3
  • 24
    • 5844370499 scopus 로고    scopus 로고
    • Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma
    • Hepatoma Prevention Study Group
    • Muto Y, Moriwaki H, Ninomiya M, et al. Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. Hepatoma Prevention Study Group. N Engl J Med 1996; 334: 1561-7.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1561-1567
    • Muto, Y.1    Moriwaki, H.2    Ninomiya, M.3
  • 25
    • 0033520713 scopus 로고    scopus 로고
    • Randomized trial of fenretinide to prevent second breast malignancy in women with early breast cancer
    • Veronesi U, De Palo G, Marubini E, et al. Randomized trial of fenretinide to prevent second breast malignancy in women with early breast cancer. J Natl Cancer Inst 1999; 91: 1847-56.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 1847-1856
    • Veronesi, U.1    De Palo, G.2    Marubini, E.3
  • 26
    • 0010607277 scopus 로고
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
    • The alpha-tocopherol, beta-carotene cancer prevention study group
    • The alpha-tocopherol, beta-carotene cancer prevention study group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 1994; 330: 1029-35.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 1029-1035
  • 27
    • 0345157579 scopus 로고    scopus 로고
    • Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease
    • Hennekens CH, Buring JE, Manson JE, et al. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med 1996; 334: 1145-9.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1145-1149
    • Hennekens, C.H.1    Buring, J.E.2    Manson, J.E.3
  • 28
    • 9244262406 scopus 로고    scopus 로고
    • Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease
    • Omenn GS, Goodman GE, Thornquist MD, et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med 1996; 334: 1150-5.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1150-1155
    • Omenn, G.S.1    Goodman, G.E.2    Thornquist, M.D.3
  • 29
    • 0031835267 scopus 로고    scopus 로고
    • Co-activators and co-repressors in the integration of transcriptional responses
    • Torchia J, Glass C, Rosenfeld MG. Co-activators and co-repressors in the integration of transcriptional responses. Curr Opin Cell Biol 1998; 10: 373-83.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 373-383
    • Torchia, J.1    Glass, C.2    Rosenfeld, M.G.3
  • 30
    • 0242587820 scopus 로고    scopus 로고
    • A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
    • Kamei Y, Xu L, Heinzel T, et al. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 1996; 85: 403-14.
    • (1996) Cell , vol.85 , pp. 403-414
    • Kamei, Y.1    Xu, L.2    Heinzel, T.3
  • 31
    • 0027521592 scopus 로고
    • Nuclear receptor/AP-1 interaction
    • Pfahl M. Nuclear receptor/AP-1 interaction. Endocr Rev 1993; 14: 651-8.
    • (1993) Endocr. Rev. , vol.14 , pp. 651-658
    • Pfahl, M.1
  • 32
    • 0032956438 scopus 로고    scopus 로고
    • Ligand-activated retinoic acid receptor inhibits AP-1 transactivation by disrupting c-Jun/c-Fos dimerization
    • Zhou XF, Shen XQ, Shemshedini L. Ligand-activated retinoic acid receptor inhibits AP-1 transactivation by disrupting c-Jun/c-Fos dimerization. Mol Endocrinol 1999; 13: 276-85.
    • (1999) Mol. Endocrinol. , vol.13 , pp. 276-285
    • Zhou, X.F.1    Shen, X.Q.2    Shemshedini, L.3
  • 33
    • 0029781068 scopus 로고    scopus 로고
    • Two distinct actions of retinoid-receptor ligands
    • Chen JY, Clifford J, Zusi C, et al. Two distinct actions of retinoid-receptor ligands. Nature 1996; 382: 819-22.
    • (1996) Nature , vol.382 , pp. 819-822
    • Chen, J.Y.1    Clifford, J.2    Zusi, C.3
  • 34
    • 0030787871 scopus 로고    scopus 로고
    • Nuclear receptors in Sicily: All in the famiglia
    • Perlmann T, Evans RM. Nuclear receptors in Sicily: all in the famiglia. Cell 1997; 90: 391-7.
    • (1997) Cell , vol.90 , pp. 391-397
    • Perlmann, T.1    Evans, R.M.2
  • 35
    • 0026684811 scopus 로고
    • Induction of retinoic acid-binding protein in normal and malignant human myeloid cells by retinoic acid in acute promyelocytic leukemia patients
    • Comic M, Delva L, Guidez F, Balitrand N, Degos L, Chomienne C. Induction of retinoic acid-binding protein in normal and malignant human myeloid cells by retinoic acid in acute promyelocytic leukemia patients. Cancer Res 1992; 52: 3329-34.
    • (1992) Cancer Res. , vol.52 , pp. 3329-3334
    • Comic, M.1    Delva, L.2    Guidez, F.3    Balitrand, N.4    Degos, L.5    Chomienne, C.6
  • 36
    • 0026536835 scopus 로고
    • Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: Implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia
    • Muindi J, Frankel SR, Miller WH Jr., et al. Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia. Blood 1992; 79: 299-303.
    • (1992) Blood , vol.79 , pp. 299-303
    • Muindi, J.1    Frankel, S.R.2    Miller W.H., Jr.3
  • 38
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangersdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell 1995; 83: 841-50.
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangersdorf, D.J.1    Evans, R.M.2
  • 39
    • 0033572682 scopus 로고    scopus 로고
    • RAR-independent RXR signaling induces t(15;17) leukemia cell maturation
    • Benoit G, Altucci L, Flexor M, et al. RAR-independent RXR signaling induces t(15;17) leukemia cell maturation. EMBO J 1999; 18: 7011-8.
    • (1999) EMBO J. , vol.18 , pp. 7011-7018
    • Benoit, G.1    Altucci, L.2    Flexor, M.3
  • 40
    • 17844406380 scopus 로고    scopus 로고
    • Autonomous rexinoid death signaling is suppressed by converging signaling pathways in immature leukemia cells
    • Benoit GR, Flexor M, Besancon F, et al. Autonomous rexinoid death signaling is suppressed by converging signaling pathways in immature leukemia cells. Mol Endocrinol 2001; 15: 1154-69.
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1154-1169
    • Benoit, G.R.1    Flexor, M.2    Besancon, F.3
  • 41
    • 0029740183 scopus 로고    scopus 로고
    • Activation of specific RXR heterodimers by an antagonist of RXR homodimers
    • Lala DS, Mukherjee R, Schulman IG, et al. Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature 1996; 383: 450-3
    • (1996) Nature , vol.383 , pp. 450-453
    • Lala, D.S.1    Mukherjee, R.2    Schulman, I.G.3
  • 42
    • 17444442152 scopus 로고    scopus 로고
    • Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
    • Mukherjee R, Davies PJ, Crombie DL, et al. Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists. Nature 1997; 386: 407-10.
    • (1997) Nature , vol.386 , pp. 407-410
    • Mukherjee, R.1    Davies, P.J.2    Crombie, D.L.3
  • 43
    • 0030787871 scopus 로고    scopus 로고
    • Nuclear receptors in Sicily: All in the famiglia
    • Perlmann T, Evans RM. Nuclear receptors in Sicily: all in the famiglia. Cell 1997; 90: 391-7.
    • (1997) Cell , vol.90 , pp. 391-397
    • Perlmann, T.1    Evans, R.M.2
  • 45
    • 0035886844 scopus 로고    scopus 로고
    • Phosphorylation of retinoid X receptor alpha at serine 260 impairs its metabolism and function in human hepatocellular carcinoma
    • Matsushima-Nishiwaki R, Okuno M, Adachi S, et al. Phosphorylation of retinoid X receptor alpha at serine 260 impairs its metabolism and function in human hepatocellular carcinoma. Cancer Res 2001; 61: 7675-82.
    • (2001) Cancer Res. , vol.61 , pp. 7675-7682
    • Matsushima-Nishiwaki, R.1    Okuno, M.2    Adachi, S.3
  • 46
    • 0021680733 scopus 로고
    • Antitumor activity of vitamin A and its derivatives
    • Muto Y, Moriwaki H. Antitumor activity of vitamin A and its derivatives. J Natl Cancer Inst 1984; 73: 1389-93.
    • (1984) J. Natl. Cancer Inst. , vol.73 , pp. 1389-1393
    • Muto, Y.1    Moriwaki, H.2
  • 48
    • 1842332757 scopus 로고    scopus 로고
    • Identification of cytoplasmic actin as an abundant glutaminyl substrate for tissue transglutaminase in HL-60 and U937 cells undergoing apoptosis
    • Nemes Z Jr., Adany R, Balazs M, Boross P, Fesus L. Identification of cytoplasmic actin as an abundant glutaminyl substrate for tissue transglutaminase in HL-60 and U937 cells undergoing apoptosis. J Biol Chem 1997; 272: 20577-83.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20577-20583
    • Nemes Z., Jr.1    Adany, R.2    Balazs, M.3    Boross, P.4    Fesus, L.5
  • 49
    • 0030863635 scopus 로고    scopus 로고
    • Tissue transglutaminase-dependent posttranslational modification of the retinoblastoma gene product in promonocytic cells undergoing apoptosis
    • Oliverio S, Amendola A, Di Sano F, et al. Tissue transglutaminase-dependent posttranslational modification of the retinoblastoma gene product in promonocytic cells undergoing apoptosis. Mol Cell Biol 1997; 17: 6040-8.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 6040-6048
    • Oliverio, S.1    Amendola, A.2    Di Sano, F.3
  • 50
    • 0028060558 scopus 로고
    • Tissue transglutaminase and apoptosis: Sense and antisense transfection studies with human neuroblastoma cells
    • Melino G, Annicchiarico-Petruzzelli M, Piredda L, et al. Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells. Mol Cell Biol 1994; 14: 6584-96.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 6584-6596
    • Melino, G.1    Annicchiarico-Petruzzelli, M.2    Piredda, L.3
  • 51
    • 0034634295 scopus 로고    scopus 로고
    • Retinoic acid-induced tissue transglutaminase and apoptosis in vascular smooth muscle cells
    • Ou H, Haendeler J, Aebly MR, et al. Retinoic acid-induced tissue transglutaminase and apoptosis in vascular smooth muscle cells. Circ Res 2000; 87: 881-7.
    • (2000) Circ. Res. , vol.87 , pp. 881-887
    • Ou, H.1    Haendeler, J.2    Aebly, M.R.3
  • 52
    • 0030051022 scopus 로고    scopus 로고
    • Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter
    • Nagy L, Saydak M, Shipley N, et al. Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter. J Biol Chem 1996; 271: 4355-65.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4355-4365
    • Nagy, L.1    Saydak, M.2    Shipley, N.3
  • 53
    • 0032528172 scopus 로고    scopus 로고
    • Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest
    • Yen A, Roberson MS, Varvayanis S, Lee AT. Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest. Cancer Res 1998; 58: 3163-72.
    • (1998) Cancer Res. , vol.58 , pp. 3163-3172
    • Yen, A.1    Roberson, M.S.2    Varvayanis, S.3    Lee, A.T.4
  • 54
    • 0033527065 scopus 로고    scopus 로고
    • Interdependent action of RaIGEF and Erk in Ras-induced primitive endoderm differentiation of F9 embryonal carcinoma cells
    • Verheijen MH, Wolthuis RM, Defize LH, den Hertog J, Bos JL. Interdependent action of RaIGEF and Erk in Ras-induced primitive endoderm differentiation of F9 embryonal carcinoma cells. Oncogene 1999; 18: 4435-9.
    • (1999) Oncogene , vol.18 , pp. 4435-4439
    • Verheijen, M.H.1    Wolthuis, R.M.2    Defize, L.H.3    den Hertog, J.4    Bos, J.L.5
  • 55
    • 0031742047 scopus 로고    scopus 로고
    • Integration of growth factor, extracellular matrix, and retinoid signals during bronchial epithelial cell differentiation
    • Moghal N, Neel BG. Integration of growth factor, extracellular matrix, and retinoid signals during bronchial epithelial cell differentiation. Mol Cell Biol 1998; 18: 6666-78.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 6666-6678
    • Moghal, N.1    Neel, B.G.2
  • 56
    • 0031440878 scopus 로고    scopus 로고
    • Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7
    • Rochette-Egly C, Adam S, Rossignol M, Egly JM, Chambon P. Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7. Cell 1997; 90: 97-107.
    • (1997) Cell , vol.90 , pp. 97-107
    • Rochette-Egly, C.1    Adam, S.2    Rossignol, M.3    Egly, J.M.4    Chambon, P.5
  • 57
    • 0034698181 scopus 로고    scopus 로고
    • TFIIH interacts with the retinoic acid receptor gamma and phosphorylates its AF-1-activating domain through cdk7
    • Bastien J, Adam-Stitah S, Riedl T, Egly JM, Chambon P, Rochette-Egly C. TFIIH interacts with the retinoic acid receptor gamma and phosphorylates its AF-1-activating domain through cdk7. J Biol Chem 2000; 275: 21896-904.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21896-21904
    • Bastien, J.1    Adam-Stitah, S.2    Riedl, T.3    Egly, J.M.4    Chambon, P.5    Rochette-Egly, C.6
  • 58
    • 0037067716 scopus 로고    scopus 로고
    • Down-regulation of the phosphatidylinositol 3-kinase/Akt pathway is involved in retinoic acid-induced phosphorylation, degradation, and transcriptional activity of retinoic acid receptor gamma 2
    • Gianni M, Kopf E, Bastien J, et al. Down-regulation of the phosphatidylinositol 3-kinase/Akt pathway is involved in retinoic acid-induced phosphorylation, degradation, and transcriptional activity of retinoic acid receptor gamma 2. J Biol Chem 2002; 277: 24859-62.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24859-24862
    • Gianni, M.1    Kopf, E.2    Bastien, J.3
  • 59
    • 0035133227 scopus 로고    scopus 로고
    • Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
    • Kim AH, Khursigara G, Sun X, Franke TF, Chao MV. Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol 2001; 21: 893-901.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 893-901
    • Kim, A.H.1    Khursigara, G.2    Sun, X.3    Franke, T.F.4    Chao, M.V.5
  • 60
    • 0034845958 scopus 로고    scopus 로고
    • PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
    • Lawlor MA, Alessi DR. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J Cell Sci 2001; 114: 2903-10.
    • (2001) J. Cell Sci. , vol.114 , pp. 2903-2910
    • Lawlor, M.A.1    Alessi, D.R.2
  • 61
    • 0037169526 scopus 로고    scopus 로고
    • Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation
    • Park HS, Kim MS, Huh SH, et al. Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation. J Biol Chem 2002; 277: 2573-8.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2573-2578
    • Park, H.S.1    Kim, M.S.2    Huh, S.H.3
  • 62
    • 0035839556 scopus 로고    scopus 로고
    • Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells
    • Gratton JP, Morales-Ruiz M, Kureishi Y, Fulton D, Walsh K, Sessa WC. Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells. J Biol Chem 2001; 276: 30359-65.
    • (2001) J. Biol. Chem. , vol.276 , pp. 30359-30365
    • Gratton, J.P.1    Morales-Ruiz, M.2    Kureishi, Y.3    Fulton, D.4    Walsh, K.5    Sessa, W.C.6
  • 63
    • 0028179948 scopus 로고
    • Chemoprevention of OH-BBN-induced bladder cancer in mice by oltipraz, alone and in combination with 4-HPR and DFMO
    • Moon RC, Kelloff GJ, Detrisac CJ, Steele VE, Thomas CF, Sigman CC. Chemoprevention of OH-BBN-induced bladder cancer in mice by oltipraz, alone and in combination with 4-HPR and DFMO. Anticancer Res 1994; 14: 5-11.
    • (1994) Anticancer Res. , vol.14 , pp. 5-11
    • Moon, R.C.1    Kelloff, G.J.2    Detrisac, C.J.3    Steele, V.E.4    Thomas, C.F.5    Sigman, C.C.6
  • 64
    • 0029044431 scopus 로고
    • Suppression of retinoic acid receptor-beta in premalignant oral lesions and its up-regulation by isotretinoin
    • Lotan R, Xu XC, Lippman SM, et al. Suppression of retinoic acid receptor-beta in premalignant oral lesions and its up-regulation by isotretinoin. N Engl J Med 1995; 332: 1405-10.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1405-1410
    • Lotan, R.1    Xu, X.C.2    Lippman, S.M.3
  • 65
    • 0032006028 scopus 로고    scopus 로고
    • Beyond tamoxifen: The retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma
    • Bischoff ED, Gottardis MM, Moon TE, Heyman RA, Lamph WW. Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma. Cancer Res 1998; 58: 479-84.
    • (1998) Cancer Res. , vol.58 , pp. 479-484
    • Bischoff, E.D.1    Gottardis, M.M.2    Moon, T.E.3    Heyman, R.A.4    Lamph, W.W.5
  • 67
    • 0036206787 scopus 로고    scopus 로고
    • Apoptosis of squamous cells at different stages of carcinogenesis following 4-HPR treatment
    • Bruno S, Tenca C, Saverino D, Ciccone E, Grossi CE. Apoptosis of squamous cells at different stages of carcinogenesis following 4-HPR treatment. Carcinogenesis 2002; 23: 447-56.
    • (2002) Carcinogenesis , vol.23 , pp. 447-456
    • Bruno, S.1    Tenca, C.2    Saverino, D.3    Ciccone, E.4    Grossi, C.E.5
  • 68
    • 0035922184 scopus 로고    scopus 로고
    • N-(4-hydroxyphenyl)retinamide (4-HPR) decreases neoplastic properties of human prostate cells: An agent for prevention
    • Sharp RM, Bello-DeOcampo D, Quader ST, Webber MM. N-(4-hydroxyphenyl)retinamide (4-HPR) decreases neoplastic properties of human prostate cells: an agent for prevention. Mutat Res 2001; 496: 163-70.
    • (2001) Mutat. Res. , vol.496 , pp. 163-170
    • Sharp, R.M.1    Bello-DeOcampo, D.2    Quader, S.T.3    Webber, M.M.4
  • 69
    • 0033794633 scopus 로고    scopus 로고
    • In vitro effects of fenretinide on cell-matrix interactions
    • Vaccari M, Silingardi P, Argnani A, et al. In vitro effects of fenretinide on cell-matrix interactions. Anticancer Res 2000; 20: 3059-66.
    • (2000) Anticancer Res. , vol.20 , pp. 3059-3066
    • Vaccari, M.1    Silingardi, P.2    Argnani, A.3
  • 70
    • 0034610009 scopus 로고    scopus 로고
    • Apoptosis and restriction of G(1)/S cell cycle by fenretinide in Burkitt's lymphoma mutu I cell line accessed with bcl-6 down- regulation
    • Hsieh T, Wu JM. Apoptosis and restriction of G(1)/S cell cycle by fenretinide in Burkitt's lymphoma mutu I cell line accessed with bcl-6 down- regulation. Biochem Biophys Res Commun 2000; 276: 1295-301.
    • (2000) Biochem. Biophys. Res. Commun. , vol.276 , pp. 1295-1301
    • Hsieh, T.1    Wu, J.M.2
  • 71
    • 0033029078 scopus 로고    scopus 로고
    • Inhibition of proliferation and induction of apoptosis in soft tissue sarcoma cells by interferon-alpha and retinoids
    • Brodowicz T, Wiltschke C, Kandioler-Eckersberger D, et al. Inhibition of proliferation and induction of apoptosis in soft tissue sarcoma cells by interferon-alpha and retinoids. Br J Cancer 1999; 80: 1350-8.
    • (1999) Br. J. Cancer , vol.80 , pp. 1350-1358
    • Brodowicz, T.1    Wiltschke, C.2    Kandioler-Eckersberger, D.3
  • 72
    • 0032908267 scopus 로고    scopus 로고
    • Inhibition of aberrant proliferation and induction of apoptosis in HER-2/neu oncogene transformed human mammary epithelial cells by N-(4-hydroxyphenyl)retinamide
    • Jinno H, Steiner MG, Mehta RG, Osborne MP, Telang NT. Inhibition of aberrant proliferation and induction of apoptosis in HER-2/neu oncogene transformed human mammary epithelial cells by N-(4-hydroxyphenyl)retinamide. Carcinogenesis 1999; 20: 229-36.
    • (1999) Carcinogenesis , vol.20 , pp. 229-236
    • Jinno, H.1    Steiner, M.G.2    Mehta, R.G.3    Osborne, M.P.4    Telang, N.T.5
  • 73
    • 0033554632 scopus 로고    scopus 로고
    • 4HPR triggers apoptosis but not differentiation in retinoid sensitive and resistant human embryonal carcinoma cells through an RARgamma independent pathway
    • Kitareewan S, Spinella MJ, Allopenna J, Reczek PR, Dmittovsky E. 4HPR triggers apoptosis but not differentiation in retinoid sensitive and resistant human embryonal carcinoma cells through an RARgamma independent pathway. Oncogene 1999; 18: 5747-55.
    • (1999) Oncogene , vol.18 , pp. 5747-5755
    • Kitareewan, S.1    Spinella, M.J.2    Allopenna, J.3    Reczek, P.R.4    Dmitrovsky, E.5
  • 74
    • 0027332981 scopus 로고
    • N-(4-hydroxyphenyl) retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid
    • Delia D, Aiello A, Lombardi L, et al. N-(4-hydroxyphenyl) retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid. Cancer Res 1993; 53: 6036-41.
    • (1993) Cancer Res. , vol.53 , pp. 6036-6041
    • Delia, D.1    Aiello, A.2    Lombardi, L.3
  • 75
    • 0030744057 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells
    • Oridate N, Suzuki S, Higuchi M, Mitchell MF, Hong WK, Lotan R. Involvement of reactive oxygen species in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells. J Natl Cancer Inst 1997; 89: 1191-8.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1191-1198
    • Oridate, N.1    Suzuki, S.2    Higuchi, M.3    Mitchell, M.F.4    Hong, W.K.5    Lotan, R.6
  • 76
    • 0029787426 scopus 로고    scopus 로고
    • 4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors
    • Fanjul AN, Delia D, Pierotti MA, et al. 4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors. J Biol Chem 1996; 271: 22441-6.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22441-22446
    • Fanjul, A.N.1    Delia, D.2    Pierotti, M.A.3
  • 77
  • 79
    • 0033579930 scopus 로고    scopus 로고
    • A selective retinoid with high activity against an androgen-resistant prostate cancer cell type
    • Lu XP, Fanjul A, Picard N, Shroot B, Pfahl M. A selective retinoid with high activity against an androgen-resistant prostate cancer cell type. Int J Cancer 1999; 80: 272-8.
    • (1999) Int. J. Cancer , vol.80 , pp. 272-278
    • Lu, X.P.1    Fanjul, A.2    Picard, N.3    Shroot, B.4    Pfahl, M.5
  • 80
  • 81
    • 0023736027 scopus 로고
    • Inhibitory effects of synthetic acidic retinoid and polyprenoic acid on the development of hepatoma in rats induced by 3'-methyl-N,N-dimethyl-4-aminoazobenzene
    • Moriwaki H, Muto Y, Ninomiya M, Kawai K, Suzuki Y, Seto T. Inhibitory effects of synthetic acidic retinoid and polyprenoic acid on the development of hepatoma in rats induced by 3'-methyl-N,N-dimethyl-4-aminoazobenzene. Gastroenterol Jpn 1988; 23: 546-52.
    • (1988) Gastroenterol. Jpn. , vol.23 , pp. 546-552
    • Moriwaki, H.1    Muto, Y.2    Ninomiya, M.3    Kawai, K.4    Suzuki, Y.5    Seto, T.6
  • 82
    • 0035702637 scopus 로고    scopus 로고
    • Chemoprevention of hepatocellular carcinoma: Concept, progress and perspectives
    • Okuno M, Kojima S, Moriwaki H. Chemoprevention of hepatocellular carcinoma: concept, progress and perspectives. J Gastroenterol Hepatol 2001; 16: 1329-35.
    • (2001) J. Gastroenterol. Hepatol. , vol.16 , pp. 1329-1335
    • Okuno, M.1    Kojima, S.2    Moriwaki, H.3
  • 83
    • 0033118925 scopus 로고    scopus 로고
    • Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma
    • Muto Y, Moriwaki H, Saito A. Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma. N Engl J Med 1999; 340: 1046-7.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1046-1047
    • Muto, Y.1    Moriwaki, H.2    Saito, A.3
  • 84
    • 0030917861 scopus 로고    scopus 로고
    • Deletion of serum lectin-reactive alpha-fetoprotein by acyclic retinoid: A potent biomarker in the chemoprevention of second primary hepatoma
    • Moriwaki H, Yasuda I, Shiratori Y, Uematsu T, Okuno M, Muto Y. Deletion of serum lectin-reactive alpha-fetoprotein by acyclic retinoid: a potent biomarker in the chemoprevention of second primary hepatoma, Clin Cancer Res 1997; 3: 727-31.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 727-731
    • Moriwaki, H.1    Yasuda, I.2    Shiratori, Y.3    Uematsu, T.4    Okuno, M.5    Muto, Y.6
  • 85
    • 0034152255 scopus 로고    scopus 로고
    • Transglutaminase and apoptosis
    • Kojima S, Ichinose A. Transglutaminase and apoptosis. Seikagaku 2000; 72: 198-202.
    • (2000) Seikagaku , vol.72 , pp. 198-202
    • Kojima, S.1    Ichinose, A.2
  • 86
    • 0027336491 scopus 로고
    • Mammalian G1 cyclins
    • Sherr CJ. Mammalian G1 cyclins. Cell 1993; 73: 1059-65.
    • (1993) Cell , vol.73 , pp. 1059-1065
    • Sherr, C.J.1
  • 87
    • 0027938209 scopus 로고
    • Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age
    • Hunter T, Pines J. Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell 1994; 79: 573-82.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 88
    • 0029921317 scopus 로고    scopus 로고
    • Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer
    • Hall M, Peters G. Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Adv Cancer Res 1996; 68: 67-108.
    • (1996) Adv. Cancer Res. , vol.68 , pp. 67-108
    • Hall, M.1    Peters, G.2
  • 89
    • 0032834039 scopus 로고    scopus 로고
    • Retinoic acid modulates a bimodal effect on cell cycle progression in human adult T-cell leukemia cells
    • Dierov J, Sawaya BE, Prosniak M, Gartenhaus RB. Retinoic acid modulates a bimodal effect on cell cycle progression in human adult T-cell leukemia cells. Clin Cancer Res 1999; 5: 2540-7.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2540-2547
    • Dierov, J.1    Sawaya, B.E.2    Prosniak, M.3    Gartenhaus, R.B.4
  • 90
    • 0029956857 scopus 로고    scopus 로고
    • Inhibited transformation of immortalized human bronchial epithelial cells by retinoic acid is linked to cyclin E down-regulation
    • Langenfeld J, Lonardo F, Kiyokawa H, et al. Inhibited transformation of immortalized human bronchial epithelial cells by retinoic acid is linked to cyclin E down-regulation. Oncogene 1996; 13: 1983-90.
    • (1996) Oncogene , vol.13 , pp. 1983-1990
    • Langenfeld, J.1    Lonardo, F.2    Kiyokawa, H.3
  • 92
    • 0033577059 scopus 로고    scopus 로고
    • Cyclin D1 proteolysis: A retinoid chemoprevention signal in normal, immortalized, and transformed human bronchial epithelial cells
    • Boyle JO, Langenfeld J, Lonardo F, et al. Cyclin D1 proteolysis: a retinoid chemoprevention signal in normal, immortalized, and transformed human bronchial epithelial cells. J Natl Cancer Inst 1999; 91: 373-9.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 373-379
    • Boyle, J.O.1    Langenfeld, J.2    Lonardo, F.3
  • 93
    • 0033618250 scopus 로고    scopus 로고
    • Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation
    • Spinella MJ, Freemantle SJ, Sekula D, Chang JH, Christie AJ, Dmitrovsky E. Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation. J Biol Chem 1999; 274: 22013-8.
    • (1999) J. Biol. Chem. , vol.274 , pp. 22013-22018
    • Spinella, M.J.1    Freemantle, S.J.2    Sekula, D.3    Chang, J.H.4    Christie, A.J.5    Dmitrovsky, E.6
  • 94
    • 0034661890 scopus 로고    scopus 로고
    • Glucocorticoids promote the proliferation and antagonize the retinoic acid-mediated growth suppression of Epstein-Barr virus-immortalized B lymphocytes
    • Quaia M, Zancai P, Cariati R, Rizzo S, Boiocchi M, Dolcetti R. Glucocorticoids promote the proliferation and antagonize the retinoic acid-mediated growth suppression of Epstein-Barr virus-immortalized B lymphocytes. Blood 2000; 96: 711-8.
    • (2000) Blood , vol.96 , pp. 711-718
    • Quaia, M.1    Zancai, P.2    Cariati, R.3    Rizzo, S.4    Boiocchi, M.5    Dolcetti, R.6
  • 95
    • 0034624704 scopus 로고    scopus 로고
    • Modulation of retinoic acid receptor function alters the growth inhibitory response of oral SCC cells to retinoids
    • Le Q, Dawson MI, Soprano DR, Soprano KJ. Modulation of retinoic acid receptor function alters the growth inhibitory response of oral SCC cells to retinoids. Oncogene 2000; 19: 1457-65.
    • (2000) Oncogene , vol.19 , pp. 1457-1465
    • Le, Q.1    Dawson, M.I.2    Soprano, D.R.3    Soprano, K.J.4
  • 96
    • 0032588229 scopus 로고    scopus 로고
    • The RARgamma selective agonist CD437 inhibits gastric cell growth through the mechanism of apoptosis
    • Jiang SY, Lin DY, Shyu RY, Reichert U, Yeh MY. The RARgamma selective agonist CD437 inhibits gastric cell growth through the mechanism of apoptosis. Cancer Lett 1999; 137: 217-25.
    • (1999) Cancer Lett. , vol.137 , pp. 217-225
    • Jiang, S.Y.1    Lin, D.Y.2    Shyu, R.Y.3    Reichert, U.4    Yeh, M.Y.5
  • 97
    • 0032500615 scopus 로고    scopus 로고
    • Overexpressed activated retinoid X receptors can mediate growth inhibitory effects of retinoids in human carcinoma cells
    • Wan H, Dawson MI, Hong WK, Lotan R. Overexpressed activated retinoid X receptors can mediate growth inhibitory effects of retinoids in human carcinoma cells. J Biol Chem 1998; 273: 26915-22.
    • (1998) J. Biol. Chem. , vol.273 , pp. 26915-26922
    • Wan, H.1    Dawson, M.I.2    Hong, W.K.3    Lotan, R.4
  • 98
    • 0010607277 scopus 로고
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
    • The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. N Engl J Med 1994; 330: 1029-35.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 1029-1035
  • 99
    • 0342854152 scopus 로고    scopus 로고
    • Growth inhibition of gastric cancer cells by all-trans retinoic acid through arresting cell cycle progression
    • Wu Q, Chen Z, Su W. Growth inhibition of gastric cancer cells by all-trans retinoic acid through arresting cell cycle progression. Chin Med J 2001; 114: 958-61.
    • (2001) Chin. Med. J. , vol.114 , pp. 958-961
    • Wu, Q.1    Chen, Z.2    Su, W.3
  • 100
    • 0033179266 scopus 로고    scopus 로고
    • Posttranslational mechanisms contribute to the suppression of specific cyclin: CDK complexes by all-trans retinoic acid in human bronchial epithelial cells
    • Sueoka N, Lee HY, Walsh GL, Hong WK, Kurie JM. Posttranslational mechanisms contribute to the suppression of specific cyclin: CDK complexes by all-trans retinoic acid in human bronchial epithelial cells. Cancer Res 1999; 59: 3838-44.
    • (1999) Cancer Res. , vol.59 , pp. 3838-3844
    • Sueoka, N.1    Lee, H.Y.2    Walsh, G.L.3    Hong, W.K.4    Kurie, J.M.5
  • 101
    • 0028313025 scopus 로고
    • Tumor-suppressor genes in breast cancer progression
    • Smith HS. Tumor-suppressor genes in breast cancer progression. Cancer Treat Res 1994; 71: 79-96.
    • (1994) Cancer Treat. Res. , vol.71 , pp. 79-96
    • Smith, H.S.1
  • 102
    • 0033516659 scopus 로고    scopus 로고
    • All-trans-retinoic acid-mediated growth inhibition involves inhibition of human kinesin-related protein HsEg5
    • Kaiser A, Brembeck FH, Nicke B, Wiedenmann B, Riecken EO, Rosewicz S. All-trans-retinoic acid-mediated growth inhibition involves inhibition of human kinesin-related protein HsEg5. J Biol Chem 1999; 274: 18925-31.
    • (1999) J. Biol. Chem. , vol.274 , pp. 18925-18931
    • Kaiser, A.1    Brembeck, F.H.2    Nicke, B.3    Wiedenmann, B.4    Riecken, E.O.5    Rosewicz, S.6
  • 103
    • 0034595637 scopus 로고    scopus 로고
    • Evidence that retinoic acid receptor beta induction by retinoids is important for tumor cell growth inhibition
    • Sun SY, Wan H, Yue P, Hong WK, Lotan R. Evidence that retinoic acid receptor beta induction by retinoids is important for tumor cell growth inhibition. J Biol Chem 2000; 275: 17149-53.
    • (2000) J. Biol. Chem. , vol.275 , pp. 17149-17153
    • Sun, S.Y.1    Wan, H.2    Yue, P.3    Hong, W.K.4    Lotan, R.5
  • 104
    • 0025759209 scopus 로고
    • Induction of transforming growth factor-beta 1 (TGF-beta 1), receptor expression and TGF-beta 1 protein production in retinoic acid-treated HL-60 cells: Possible TGF-beta 1-mediated autocrine inhibition
    • Falk LA, De Benedetti F, Lohrey N, et al. Induction of transforming growth factor-beta 1 (TGF-beta 1), receptor expression and TGF-beta 1 protein production in retinoic acid-treated HL-60 cells: possible TGF-beta 1-mediated autocrine inhibition. Blood 1991; 77: 1248-55.
    • (1991) Blood , vol.77 , pp. 1248-1255
    • Falk, L.A.1    De Benedetti, F.2    Lohrey, N.3
  • 105
    • 0029975905 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein 3 mediates retinoic acid-and transforming growth factor beta2-induced growth inhibition in human breast cancer cells
    • Gucev ZS, Oh Y, Kelley KM, Rosenfeld RG. Insulin-like growth factor binding protein 3 mediates retinoic acid-and transforming growth factor beta2-induced growth inhibition in human breast cancer cells. Cancer Res 1996; 56: 1545-50.
    • (1996) Cancer Res. , vol.56 , pp. 1545-1550
    • Gucev, Z.S.1    Oh, Y.2    Kelley, K.M.3    Rosenfeld, R.G.4
  • 106
    • 0029955958 scopus 로고    scopus 로고
    • Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation
    • Liu M, Iavarone A, Freedman LP. Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation. J Biol Chem 1996; 271: 31723-8.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31723-31728
    • Liu, M.1    Iavarone, A.2    Freedman, L.P.3
  • 107
    • 0028947023 scopus 로고
    • Evidence for the involvement of retinolc acid receptor RAR alpha-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids
    • Zhang LX, Mills KJ, Dawson MI, Collins SJ, Jetten AM. Evidence for the involvement of retinolc acid receptor RAR alpha-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids. J Biol Chem 1995; 270: 6022-9.
    • (1995) J. Biol. Chem. , vol.270 , pp. 6022-6029
    • Zhang, L.X.1    Mills, K.J.2    Dawson, M.I.3    Collins, S.J.4    Jetten, A.M.5
  • 108
    • 0033564118 scopus 로고    scopus 로고
    • Implication of p53 in growth arrest and apoptosis induced by the synthetic retinoid CD437 in human lung cancer cells
    • Sun SY, Yue P, Wu GS, et al. Implication of p53 in growth arrest and apoptosis induced by the synthetic retinoid CD437 in human lung cancer cells. Cancer Res 1999; 59: 2829-33.
    • (1999) Cancer Res. , vol.59 , pp. 2829-2833
    • Sun, S.Y.1    Yue, P.2    Wu, G.S.3
  • 109
    • 0022543492 scopus 로고
    • Decreased c-myc expression is an early event in retinoic acid-induced differentiation of F9 teratocarcinoma cells
    • Griep AE, DeLuca HF. Decreased c-myc expression is an early event in retinoic acid-induced differentiation of F9 teratocarcinoma cells. Proc Natl Acad Sci USA 1986; 83: 5539-43.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 5539-5543
    • Griep, A.E.1    DeLuca, H.F.2
  • 110
    • 0033022916 scopus 로고    scopus 로고
    • Retinoic acid repressed the expression of c-fos and c-jun and induced apoptosis in regenerating rat liver after partial hepatectomy
    • 1450
    • Ozeki A, Tsukamoto I. Retinoic acid repressed the expression of c-fos and c-jun and induced apoptosis in regenerating rat liver after partial hepatectomy. Biochim Biophys Acta 1999; 1450: 308-19.
    • (1999) Biochim. Biophys. Acta , pp. 308-319
    • Ozeki, A.1    Tsukamoto, I.2
  • 111
    • 0034192212 scopus 로고    scopus 로고
    • Retinoic acid and its receptors repress the expression and transactivation functions of Nur77: A possible mechanism for the inhibition of apoptosis by retinoic acid
    • Kang HJ, Song MR, Lee SK, et al. Retinoic acid and its receptors repress the expression and transactivation functions of Nur77: a possible mechanism for the inhibition of apoptosis by retinoic acid. Exp Cell Res 2000; 256: 545-54.
    • (2000) Exp. Cell Res. , vol.256 , pp. 545-554
    • Kang, H.J.1    Song, M.R.2    Lee, S.K.3
  • 112
    • 0030899367 scopus 로고    scopus 로고
    • Modulation of interferon action by retinoids. Induction of murine STAT1 gene expression by retinoic acid
    • Kolla W, Weilhua X, Kalvakolanu DV. Modulation of interferon action by retinoids. Induction of murine STAT1 gene expression by retinoic acid. J Biol Chem 1997; 272: 9742-8.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9742-9748
    • Kolla, W.1    Weilhua, X.2    Kalvakolanu, D.V.3
  • 113
    • 0032948740 scopus 로고    scopus 로고
    • Post-transcriptional regulation of MyD118 and GADD45 in human lung carcinoma cells during 6-[3-(1-adamantyl)-4-hydro-xyphenyl]-2-naphthalene carboxylic acid-induced apoptosis
    • Sakaue M, Adachi H, Jetten AM. Post-transcriptional regulation of MyD118 and GADD45 in human lung carcinoma cells during 6-[3-(1-adamantyl)-4-hydro-xyphenyl]-2-naphthalene carboxylic acid-induced apoptosis. Mol Pharmacol 1999; 55: 668-76.
    • (1999) Mol. Pharmacol. , vol.55 , pp. 668-676
    • Sakaue, M.1    Adachi, H.2    Jetten, A.M.3
  • 114
    • 0029818411 scopus 로고    scopus 로고
    • Retinoids and their receptors in modulation of differentiation, development, and prevention of head and neck cancers
    • Lotan R. Retinoids and their receptors in modulation of differentiation, development, and prevention of head and neck cancers. Anticancer Res 1996; 16: 2415-9.
    • (1996) Anticancer Res. , vol.16 , pp. 2415-2419
    • Lotan, R.1
  • 115
    • 0033166850 scopus 로고    scopus 로고
    • Implication of c-Myc in apoptosis induced by the retinoid CD437 in human lung carcinoma cells
    • Sun SY, Yue P, Shroot B, Hong WK, Lotan R. Implication of c-Myc in apoptosis induced by the retinoid CD437 in human lung carcinoma cells. Oncogene 1999; 18: 3894-901.
    • (1999) Oncogene , vol.18 , pp. 3894-3901
    • Sun, S.Y.1    Yue, P.2    Shroot, B.3    Hong, W.K.4    Lotan, R.5
  • 116
    • 0031830509 scopus 로고    scopus 로고
    • Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines
    • Li Y, Lin B, Agadir A, et al. Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol 1998; 18: 4719-31.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 4719-4731
    • Li, Y.1    Lin, B.2    Agadir, A.3
  • 117
    • 0036052395 scopus 로고    scopus 로고
    • Retinoid-induced growth arrest of breast carcinoma cells involves co-activation of multiple growth-inhibitory genes
    • discussion 28-30
    • Dokmanovic M, Chang BD, Fang J, Roninson IB. Retinoid-induced growth arrest of breast carcinoma cells involves co-activation of multiple growth-inhibitory genes. Cancer Biol Ther 2002; 1: 24-7; discussion 28-30.
    • (2002) Cancer Biol. Ther. , vol.1 , pp. 24-27
    • Dokmanovic, M.1    Chang, B.D.2    Fang, J.3    Roninson, I.B.4
  • 118
    • 0024755673 scopus 로고
    • Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis
    • Glick AB, Flanders KC, Danielpour D, Yuspa SH, Sporn MB. Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis. Cell Regul 1989; 1: 87-97.
    • (1989) Cell Regul. , vol.1 , pp. 87-97
    • Glick, A.B.1    Flanders, K.C.2    Danielpour, D.3    Yuspa, S.H.4    Sporn, M.B.5
  • 119
    • 0029810023 scopus 로고    scopus 로고
    • Regulation of gene expression of a binding protein for fibroblast growth factors by retinoic acid
    • Liaudet-Coopman ED, Wellstein A. Regulation of gene expression of a binding protein for fibroblast growth factors; by retinoic acid. J Biol Chem 1996; 271: 21303-8.
    • (1996) J. Biol. Chem. , vol.271 , pp. 21303-21308
    • Liaudet-Coopman, E.D.1    Wellstein, A.2
  • 120
    • 0030600572 scopus 로고    scopus 로고
    • A tetracycline-responsive promoter system reveals the role of a secreted binding protein for FGFs during the early phase of tumor growth
    • Liaudet-Coopman ED, Schulte AM, Cardillo M, Wellstein A. A tetracycline-responsive promoter system reveals the role of a secreted binding protein for FGFs during the early phase of tumor growth. Biochem Biophys Res Commun 1996; 229: 930-7.
    • (1996) Biochem. Biophys. Res. Commun. , vol.229 , pp. 930-937
    • Liaudet-Coopman, E.D.1    Schulte, A.M.2    Cardillo, M.3    Wellstein, A.4
  • 121
    • 0033559268 scopus 로고    scopus 로고
    • Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors
    • Xiao JH, Feng X, Di W, et al. Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors. EMBO J 1999; 18: 1539-48.
    • (1999) EMBO J. , vol.18 , pp. 1539-1548
    • Xiao, J.H.1    Feng, X.2    Di, W.3
  • 122
    • 0026772696 scopus 로고
    • Regulation of insulin-like growth factor I production in rat C6 glioma cells: Possible role as an autocrine/paracrine growth factor
    • Lowe WL Jr, Meyer T, Karpen CW, Lorentzen LR. Regulation of insulin-like growth factor I production in rat C6 glioma cells: possible role as an autocrine/paracrine growth factor. Endocrinology 1992; 130: 2683-91.
    • (1992) Endocrinology , vol.130 , pp. 2683-2691
    • Lowe W.L., Jr.1    Meyer, T.2    Karpen, C.W.3    Lorentzen, L.R.4
  • 123
    • 0025971180 scopus 로고
    • Retinoid modulation of insulin-like growth factor-binding proteins and inhibition of breast carcinoma proliferation
    • Fontana A Burrows-Mezu A, Clemmons DR, LeRoith D. Retinoid modulation of insulin-like growth factor-binding proteins and inhibition of breast carcinoma proliferation. Endocrinology 1991; 128: 1115-22.
    • (1991) Endocrinology , vol.128 , pp. 1115-1122
    • Fontana, A.1    Burrows-Mezu, A.2    Clemmons, D.R.3    LeRoith, D.4
  • 124
    • 0026574177 scopus 로고
    • Differential regulation of insulin-like growth factor binding protein (IGFBP)-2 mRNA in liver and bone cells by insulin and retinoic acid in vitro
    • Schmid C, Schlapfer I, Waldvogel M, et al. Differential regulation of insulin-like growth factor binding protein (IGFBP)-2 mRNA in liver and bone cells by insulin and retinoic acid in vitro. FEBS Lett 1992; 303: 205-9.
    • (1992) FEBS Lett. , vol.303 , pp. 205-209
    • Schmid, C.1    Schlapfer, I.2    Waldvogel, M.3
  • 125
    • 0022203144 scopus 로고
    • Stimulation of interleukin 1 and 3 production by retinoic acid in vitro
    • Trechsel U, Evequoz V, Fleisch H. Stimulation of interleukin 1 and 3 production by retinoic acid in vitro. Biochem J 1985; 230: 339-44.
    • (1985) Biochem. J. , vol.230 , pp. 339-344
    • Trechsel, U.1    Evequoz, V.2    Fleisch, H.3
  • 126
    • 0023797443 scopus 로고
    • Effects of retinoids on macrophage function and IL-1 activity
    • Dillehay DL, Walia AS, Lamon EW. Effects of retinoids on macrophage function and IL-1 activity. J Leukoc Biol 1988; 44: 353-60.
    • (1988) J. Leukoc. Biol. , vol.44 , pp. 353-360
    • Dillehay, D.L.1    Walia, A.S.2    Lamon, E.W.3
  • 127
    • 0026055865 scopus 로고
    • Retinoic acid enhances IL-1 beta expression in myeloid leukemia cells and in human monocytes
    • Matikainen S, Serkkola E, Hurme M. Retinoic acid enhances IL-1 beta expression in myeloid leukemia cells and in human monocytes. J Immunol 1991; 147: 162-7.
    • (1991) J. Immunol. , vol.147 , pp. 162-167
    • Matikainen, S.1    Serkkola, E.2    Hurme, M.3
  • 128
    • 0025873420 scopus 로고
    • Abnormal regulation of IFN-gamma secretion in vitamin A deficiency
    • Carman JA, Hayes CE. Abnormal regulation of IFN-gamma secretion in vitamin A deficiency. J Immunol 1991; 147: 1247-52.
    • (1991) J. Immunol. , vol.147 , pp. 1247-1252
    • Carman, J.A.1    Hayes, C.E.2
  • 129
    • 0030996039 scopus 로고    scopus 로고
    • Activity of retinoic acid receptor-gamma selectively binding retinoids alone and in combination with interfer-on-gamma in breast cancer cell lines
    • Widschwendter M, Daxenbichler G, Culig Z, et al. Activity of retinoic acid receptor-gamma selectively binding retinoids alone and in combination with interfer-on-gamma in breast cancer cell lines. Int J Cancer 1997; 71: 497-504.
    • (1997) Int. J. Cancer , vol.71 , pp. 497-504
    • Widschwendter, M.1    Daxenbichler, G.2    Culig, Z.3
  • 130
    • 0030972135 scopus 로고    scopus 로고
    • Retinoic acid induces signal transducer and activator of transcription (STAT) 1, STAT2, and p48 expression in myeloid leukemia cells and enhances their responsiveness to interferons
    • Matikainen S, Ronni T, Lehtonen A, et al. Retinoic acid induces signal transducer and activator of transcription (STAT) 1, STAT2, and p48 expression in myeloid leukemia cells and enhances their responsiveness to interferons. Cell Growth Differ 1997; 8: 687-98.
    • (1997) Cell Growth Differ. , vol.8 , pp. 687-698
    • Matikainen, S.1    Ronni, T.2    Lehtonen, A.3
  • 131
    • 0035480012 scopus 로고    scopus 로고
    • Interferon-gamma cooperates with retinoic acid and phorbol ester to induce differentiation and growth inhibition of human neuroblastoma cells
    • Guzhova I, Hultquist A, Cetinkaya C, Nilsson K, Pahlman S, Larsson LG. Interferon-gamma cooperates with retinoic acid and phorbol ester to induce differentiation and growth inhibition of human neuroblastoma cells. Int J Cancer 2001; 94: 97-108.
    • (2001) Int. J. Cancer , vol.94 , pp. 97-108
    • Guzhova, I.1    Hultquist, A.2    Cetinkaya, C.3    Nilsson, K.4    Pahlman, S.5    Larsson, L.G.6
  • 132
    • 0020563699 scopus 로고
    • Vitamin A status and retinoid-binding proteins in carcinomas of the head and neck region
    • Bichler E, Daxenbichler G, Marth C. Vitamin A status and retinoid-binding proteins in carcinomas of the head and neck region. Oncology 1983; 40: 336-9.
    • (1983) Oncology , vol.40 , pp. 336-339
    • Bichler, E.1    Daxenbichler, G.2    Marth, C.3
  • 133
    • 0022592690 scopus 로고
    • Studies of cellular retinol-binding protein (CRBP) in squamous-cell carcinomas of the head and neck region
    • Fex G, Wahlberg P, Biorklund A, Wennerberg J, Willen R. Studies of cellular retinol-binding protein (CRBP) in squamous-cell carcinomas of the head and neck region. Int J Cancer 1986; 37: 217-21.
    • (1986) Int. J. Cancer , vol.37 , pp. 217-221
    • Fex, G.1    Wahlberg, P.2    Biorklund, A.3    Wennerberg, J.4    Willen, R.5
  • 134
    • 0034748407 scopus 로고    scopus 로고
    • Changes of serum carotenoids in patients with esophageal, gastric, hepatocellular, pancreatic and colorectal cancer
    • Rumi G Jr, Matus Z, Toth G, et al. Changes of serum carotenoids in patients with esophageal, gastric, hepatocellular, pancreatic and colorectal cancer. J Physiol Paris 2001; 95: 239-42.
    • (2001) J. Physiol. Paris , vol.95 , pp. 239-242
    • Rumi G., Jr.1    Matus, Z.2    Toth, G.3
  • 136
    • 0033841567 scopus 로고    scopus 로고
    • Serum antioxidant micronutrients and the risk of oral leukoplakia among Japanese
    • Nagao T, Ikeda N, Warnakulasuriya S, et al. Serum antioxidant micronutrients and the risk of oral leukoplakia among Japanese. Oral Oncol 2000; 36: 466-70.
    • (2000) Oral Oncol. , vol.36 , pp. 466-470
    • Nagao, T.1    Ikeda, N.2    Warnakulasuriya, S.3
  • 137
    • 0031975456 scopus 로고    scopus 로고
    • Metabolism of all-trans-retinol in normal human cell strains and squamous cell carcinoma (SCC) lines from the oral cavity and skin: Reduced esterification of retinol in SCC lines
    • Guo X, Gudas LJ. Metabolism of all-trans-retinol in normal human cell strains and squamous cell carcinoma (SCC) lines from the oral cavity and skin: reduced esterification of retinol in SCC lines. Cancer Res 1998; 58: 166-76.
    • (1998) Cancer Res. , vol.58 , pp. 166-176
    • Guo, X.1    Gudas, L.J.2
  • 138
    • 0034910254 scopus 로고    scopus 로고
    • Enhanced turnover of all-trans-retinoic acid and increased formation of polar metabolites in head and neck squamous cell carcinoma lines compared with normal oral keratinocytes
    • Klaassen I, Brakenhoff RH, Smeets SJ, Snow GB, Braakhuis BJ. Enhanced turnover of all-trans-retinoic acid and increased formation of polar metabolites in head and neck squamous cell carcinoma lines compared with normal oral keratinocytes. Clin Cancer Res 2001; 7: 1017-25.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1017-1025
    • Klaassen, I.1    Brakenhoff, R.H.2    Smeets, S.J.3    Snow, G.B.4    Braakhuis, B.J.5
  • 139
    • 0029778148 scopus 로고    scopus 로고
    • Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis
    • Duester G. Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis. Biochemistry 1996; 35: 12221-7.
    • (1996) Biochemistry , vol.35 , pp. 12221-12227
    • Duester, G.1
  • 140
    • 0026559141 scopus 로고
    • Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal
    • Roberts ES, Vaz AD, Coon MJ. Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal. Mol Pharmacol 1992; 41: 427-33.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 427-433
    • Roberts, E.S.1    Vaz, A.D.2    Coon, M.J.3
  • 141
    • 0029918184 scopus 로고    scopus 로고
    • Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral
    • Raner GM, Vaz AD, Coon MJ. Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral. Mol Pharmacol 1996; 49: 515-22.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 515-522
    • Raner, G.M.1    Vaz, A.D.2    Coon, M.J.3
  • 142
    • 0021791268 scopus 로고
    • New pathway for retinol metabolism in liver microsomes
    • Leo MA, Lieber CS. New pathway for retinol metabolism in liver microsomes. J Biol Chem 1985; 260: 5228-31.
    • (1985) J. Biol. Chem. , vol.260 , pp. 5228-5231
    • Leo, M.A.1    Lieber, C.S.2
  • 143
    • 0032524371 scopus 로고    scopus 로고
    • Characterization of the cytochrome P450 CYP2J4: Expression in rat small intestine and role in retinoic acid biotransformation from retinal
    • Zhang QY, Raner G, Ding X, Dunbar D, Coon MJ, Kaminsky LS. Characterization of the cytochrome P450 CYP2J4: expression in rat small intestine and role in retinoic acid biotransformation from retinal. Arch Biochem Biophys 1998; 353: 257-64.
    • (1998) Arch. Biochem. Biophys. , vol.353 , pp. 257-264
    • Zhang, Q.Y.1    Raner, G.2    Ding, X.3    Dunbar, D.4    Coon, M.J.5    Kaminsky, L.S.6
  • 145
    • 0032417959 scopus 로고    scopus 로고
    • Metabolism to a response pathway selective retinoid ligand during axial pattern formation
    • Pijnappel WW, Folkers GE, de Jonge WJ, et al. Metabolism to a response pathway selective retinoid ligand during axial pattern formation. Proc Natl Acad Sci USA 1998; 95:15424-9.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15424-15429
    • Pijnappel, W.W.1    Folkers, G.E.2    de Jonge, W.J.3
  • 146
    • 0027158494 scopus 로고
    • Neurobehavioral mechanisms of nicotine action: Role in the initiation and maintenance of tobacco dependence
    • Rosecrans JA, Karan LD. Neurobehavioral mechanisms of nicotine action: role in the initiation and maintenance of tobacco dependence. J Subst Abuse Treat 1993; 10: 161-70.
    • (1993) J. Subst. Abuse Treat. , vol.10 , pp. 161-170
    • Rosecrans, J.A.1    Karan, L.D.2
  • 147
    • 0025341202 scopus 로고
    • Opioid and nicotine receptors affect growth regulation of human lung cancer cell lines
    • Maneckjee R, Minna JD. Opioid and nicotine receptors affect growth regulation of human lung cancer cell lines. Proc Natl Acad Sci USA 1990; 87: 3294-8.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 3294-3298
    • Maneckjee, R.1    Minna, J.D.2
  • 148
    • 0026502373 scopus 로고
    • Neuronal-type alpha-bungarotoxin receptors and the alpha 5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines
    • Chini B, Clementi F, Hukovic N, Sher E. Neuronal-type alpha-bungarotoxin receptors and the alpha 5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines. Proc Natl Acad Sci USA 1992; 89: 1572-6.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1572-1576
    • Chini, B.1    Clementi, F.2    Hukovic, N.3    Sher, E.4
  • 149
    • 0028168344 scopus 로고
    • Alpha-Bungarotoxin blocks the nicotinic receptor mediated increase in cell number in a neuroendocrine cell line
    • Quik M, Chan J, Patrick J. alpha-Bungarotoxin blocks the nicotinic receptor mediated increase in cell number in a neuroendocrine cell line. Brain Res 1994; 655: 161-7.
    • (1994) Brain Res. , vol.655 , pp. 161-167
    • Quik, M.1    Chan, J.2    Patrick, J.3
  • 150
    • 0032499397 scopus 로고    scopus 로고
    • Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells
    • Schuller HM, Orloff M. Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells. Biochem Pharmacol 1998; 55: 1377-84.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1377-1384
    • Schuller, H.M.1    Orloff, M.2
  • 152
    • 0037052689 scopus 로고    scopus 로고
    • Nicotine modulates the effects of retinoids on growth inhibition and RAR beta expression in lung cancer cells
    • Chen GQ, Lin B, Dawson MI, Zhang XK. Nicotine modulates the effects of retinoids on growth inhibition and RAR beta expression in lung cancer cells. Int J Cancer 2002; 99: 171-8.
    • (2002) Int. J. Cancer , vol.99 , pp. 171-178
    • Chen, G.Q.1    Lin, B.2    Dawson, M.I.3    Zhang, X.K.4
  • 153
    • 0037077307 scopus 로고    scopus 로고
    • Regulation of retinoic acid-induced inhibition of AP-1 activity by orphan receptor chicken ovalbumin upstream promoter-transcription factor
    • Lin F, Kolluri SK, Chen GQ, Zhang XK. Regulation of retinoic acid-induced inhibition of AP-1 activity by orphan receptor chicken ovalbumin upstream promoter-transcription factor. J Biol Chem 2002; 277: 21414-22.
    • (2002) J. Biol. Chem. , vol.277 , pp. 21414-21422
    • Lin, F.1    Kolluri, S.K.2    Chen, G.Q.3    Zhang, X.K.4
  • 154
    • 0033982598 scopus 로고    scopus 로고
    • Orphan receptor COUP-TF is required for induction of retinoic acid receptor beta, growth inhibition, and apoptosis by retinoic acid in cancer cells
    • Lin B, Chen GQ, Xiao D, et al. Orphan receptor COUP-TF is required for induction of retinoic acid receptor beta, growth inhibition, and apoptosis by retinoic acid in cancer cells. Mol Cell Biol 2000; 20: 957-70.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 957-970
    • Lin, B.1    Chen, G.Q.2    Xiao, D.3
  • 155
    • 0028821102 scopus 로고
    • A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor: Retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells
    • Ben-Shushan E, Sharir H, Pikarsky E, Bergman Y. A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor: retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. Mol Cell Biol 1995; 15: 1034-48.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 1034-1048
    • Ben-Shushan, E.1    Sharir, H.2    Pikarsky, E.3    Bergman, Y.4
  • 156
    • 0036327656 scopus 로고    scopus 로고
    • Vitamin A and apoptosis in prostate cancer
    • Zhang XK. Vitamin A and apoptosis in prostate cancer. Endocr Relat Cancer 2002; 9: 87-102.
    • (2002) Endocr. Relat. Cancer , vol.9 , pp. 87-102
    • Zhang, X.K.1
  • 157
    • 0034682890 scopus 로고    scopus 로고
    • Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
    • Li H, Kolluri SK, Gu J, et al. Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. Science 2000; 289: 1159-64.
    • (2000) Science , vol.289 , pp. 1159-1164
    • Li, H.1    Kolluri, S.K.2    Gu, J.3
  • 158
    • 0030764346 scopus 로고    scopus 로고
    • Inhibition of transretinoic acid-resistant human breast cancer cell growth by retinoid X receptor-selective retinoids
    • Wu Q, Dawson MI, Zheng Y, et al. Inhibition of transretinoic acid-resistant human breast cancer cell growth by retinoid X receptor-selective retinoids. Mol Cell Biol 1997; 17: 6598-608.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 6598-6608
    • Wu, Q.1    Dawson, M.I.2    Zheng, Y.3
  • 159
    • 0031731906 scopus 로고    scopus 로고
    • Demethylation by 5-aza-2′-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells
    • Cote S, Sinnett D, Momparler RL. Demethylation by 5-aza-2′-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells. Anticancer Drugs 1998; 9: 743-50.
    • (1998) Anticancer Drugs , vol.9 , pp. 743-750
    • Cote, S.1    Sinnett, D.2    Momparler, R.L.3
  • 160
    • 0034674916 scopus 로고    scopus 로고
    • Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas
    • Virmani AK, Rathi A, Zochbauer-Muller S, et al. Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas. J Natl Cancer Inst 2000; 92: 1303-7.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1303-1307
    • Virmani, A.K.1    Rathi, A.2    Zochbauer-Muller, S.3
  • 161
    • 0034810628 scopus 로고    scopus 로고
    • Effect of benzo[a]pyrene diol epoxide on expression of retinoic acid receptor-beta in immortalized esophageal epithelial cells and esophageal cancer cells
    • Song S, Xu XC. Effect of benzo[a]pyrene diol epoxide on expression of retinoic acid receptor-beta in immortalized esophageal epithelial cells and esophageal cancer cells. Biochem Biophys Res Commun 2001; 281: 872-7.
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , pp. 872-877
    • Song, S.1    Xu, X.C.2
  • 162
    • 0004002991 scopus 로고
    • Benzopyrenes
    • Cambridge University Press, Cambridge
    • Osborne MR, Crosby NT. Benzopyrenes 1987; Cambridge University Press, Cambridge.
    • (1987)
    • Osborne, M.R.1    Crosby, N.T.2
  • 163
    • 0033919180 scopus 로고    scopus 로고
    • Areca nut extract upregulates prostaglandin production, cyclooxygenase-2mRNA and protein expression of human oral keratinocytes
    • Jeng JH, Ho YS, Chan CP, et al. Areca nut extract upregulates prostaglandin production, cyclooxygenase-2mRNA and protein expression of human oral keratinocytes. Carcinogenesis 2000; 21: 1365-70.
    • (2000) Carcinogenesis , vol.21 , pp. 1365-1370
    • Jeng, J.H.1    Ho, Y.S.2    Chan, C.P.3
  • 164
    • 0034901568 scopus 로고    scopus 로고
    • Cyclooxygenase-2 over-expression is a marker of poor prognosis in stage I non-small cell lung cancer
    • Khuri FR, Wu H, Lee JJ, et al. Cyclooxygenase-2 over-expression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin Cancer Res 2001; 7: 861-7.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 861-867
    • Khuri, F.R.1    Wu, H.2    Lee, J.J.3
  • 165
    • 0030747815 scopus 로고    scopus 로고
    • Retinoids suppress epidermal growth factor-induced transcription of cyclooxygenase-2 in human oral squamous carcinoma cells
    • Mestre JR, Subbaramaiah K, Sacks PG, et al. Retinoids suppress epidermal growth factor-induced transcription of cyclooxygenase-2 in human oral squamous carcinoma cells. Cancer Res 1997; 57: 2890-5.
    • (1997) Cancer Res. , vol.57 , pp. 2890-2895
    • Mestre, J.R.1    Subbaramaiah, K.2    Sacks, P.G.3
  • 166
    • 85047696309 scopus 로고    scopus 로고
    • Induction of retinoic acid receptor-beta suppresses cyclooxygenase-2 expression in esophageal cancer cells
    • Li M, Song S, Lippman SM, et al. Induction of retinoic acid receptor-beta suppresses cyclooxygenase-2 expression in esophageal cancer cells. Oncogene 2002; 21: 411-8.
    • (2002) Oncogene , vol.21 , pp. 411-418
    • Li, M.1    Song, S.2    Lippman, S.M.3
  • 167
    • 0033578305 scopus 로고    scopus 로고
    • Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion
    • Young MR, Li JJ, Rincon M, et al. Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion. Proc Natl Acad Sci USA 1999; 96: 9827-32.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9827-9832
    • Young, M.R.1    Li, J.J.2    Rincon, M.3
  • 168
    • 0026771076 scopus 로고
    • Retinoic acid inhibition of serum-induced c-fos transcription in a fibrosarcoma cell line
    • Jaffey P, Chan LN, Shao J, Schneider-Schaulies J, Chan TS. Retinoic acid inhibition of serum-induced c-fos transcription in a fibrosarcoma cell line. Cancer Res 1992; 52: 2384-8.
    • (1992) Cancer Res. , vol.52 , pp. 2384-2388
    • Jaffey, P.1    Chan, L.N.2    Shao, J.3    Schneider-Schaulies, J.4    Chan, T.S.5
  • 169
    • 0026316847 scopus 로고
    • Antagonism between retinoic acid receptors and AP-1: Implications for tumor promotion and inflammation
    • Yang-Yen HF, Zhang XK, Graupner G, et al. Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation. New Biol 1991; 3:1206-19.
    • (1991) New Biol. , vol.3 , pp. 1206-1219
    • Yang-Yen, H.F.1    Zhang, X.K.2    Graupner, G.3
  • 170
    • 0025883418 scopus 로고
    • Retinoic acid is a negative regulator of AP-1-responsive genes
    • Schule R, Rangarajan P, Yang N, et al. Retinoic acid is a negative regulator of AP-1-responsive genes. Proc Natl Acad Sci USA 1991; 88: 6092-6.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6092-6096
    • Schule, R.1    Rangarajan, P.2    Yang, N.3
  • 171
    • 0242587820 scopus 로고    scopus 로고
    • A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
    • Kamei Y, Xu L, Heinzel T, et al. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 1996; 85: 403-14.
    • (1996) Cell , vol.85 , pp. 403-414
    • Kamei, Y.1    Xu, L.2    Heinzel, T.3
  • 172
    • 0034123876 scopus 로고    scopus 로고
    • Unique anti-activator protein-1 activity of retinoic acid receptor beta
    • Lin F, Xiao D, Kolluri SK, Zhang X. Unique anti-activator protein-1 activity of retinoic acid receptor beta. Cancer Res 2000; 60: 3271-80.
    • (2000) Cancer Res. , vol.60 , pp. 3271-3280
    • Lin, F.1    Xiao, D.2    Kolluri, S.K.3    Zhang, X.4
  • 173
    • 0028173207 scopus 로고
    • A new class of retinoids with selective inhibition of AP-1 inhibits proliferation
    • Fanjul A, Dawson MI, Hobbs PD, et al. A new class of
    • (1994) Nature , vol.372 , pp. 107-111
    • Fanjul, A.1    Dawson, M.I.2    Hobbs, P.D.3
  • 175
    • 0029805772 scopus 로고    scopus 로고
    • Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells
    • Lee HY, Dawson MI, Walsh GL, et al. Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells. Cell Growth Differ 1996; 7: 997-1004.
    • (1996) Cell Growth Differ. , vol.7 , pp. 997-1004
    • Lee, H.Y.1    Dawson, M.I.2    Walsh, G.L.3
  • 177
    • 0032818740 scopus 로고    scopus 로고
    • Ets-1: A plausible marker of invasive potential and lymph node metastasis in human oral squamous cell carcinomas
    • Pande P, Mathur M, Shukla NK, Ralhan R. Ets-1: a plausible marker of invasive potential and lymph node metastasis in human oral squamous cell carcinomas. J Pathol 1999; 189: 40-5.
    • (1999) J. Pathol. , vol.189 , pp. 40-45
    • Pande, P.1    Mathur, M.2    Shukla, N.K.3    Ralhan, R.4
  • 179
    • 0035026338 scopus 로고    scopus 로고
    • Expression of the Ets-1 proto-oncogene in human colorectal carcinoma
    • Nakayama T, Ito M, Ohtsuru A, Naito S, Sekine I. Expression of the Ets-1 proto-oncogene in human colorectal carcinoma. Mod Pathol 2001; 14: 415-22.
    • (2001) Mod. Pathol. , vol.14 , pp. 415-422
    • Nakayama, T.1    Ito, M.2    Ohtsuru, A.3    Naito, S.4    Sekine, I.5
  • 180
    • 0344578062 scopus 로고    scopus 로고
    • Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Fit-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis
    • Valter MM, Hugel A, Huang HJ, et al. Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Fit-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis. Cancer Res 1999; 59: 5608-14.
    • (1999) Cancer Res. , vol.59 , pp. 5608-5614
    • Valter, M.M.1    Hugel, A.2    Huang, H.J.3
  • 182
    • 0000068917 scopus 로고    scopus 로고
    • Aberrant expression and function of retinoid receptors in cancer
    • Nau H, Blaner WS, eds. Retinoids-the biochemical and molecular basis of vitamin A and retinoid action. Berlin: Springer-Verlag
    • Xu XC, Lotan R. Aberrant expression and function of retinoid receptors in cancer. In: Nau H, Blaner WS, eds. Retinoids-the biochemical and molecular basis of vitamin A and retinoid action. handbook of experimental pharmacology, Berlin: Springer-Verlag, 1999, Vol. 139, pp. 323-43.
    • (1999) Handbook of Experimental Pharmacology , vol.139 , pp. 323-343
    • Xu, X.C.1    Lotan, R.2
  • 184
    • 0024603151 scopus 로고
    • Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells
    • Nakajima M, Lotan D, Baig MM, et al. Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells. Cancer Res 1989; 49: 1698-706.
    • (1989) Cancer Res. , vol.49 , pp. 1698-1706
    • Nakajima, M.1    Lotan, D.2    Baig, M.M.3
  • 185
    • 0025358656 scopus 로고
    • Retinoic acid inhibits human melanoma tumor cell invasion
    • Wood WR, Seftor EA, Lotan D, et al. Retinoic acid inhibits human melanoma tumor cell invasion. Anticancer Res 1990; 10: 423-32.
    • (1990) Anticancer Res. , vol.10 , pp. 423-432
    • Wood, W.R.1    Seftor, E.A.2    Lotan, D.3
  • 186
    • 0023597374 scopus 로고
    • Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts
    • Clark SD, Kobayashi DK, Welgus HG. Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts. J Clin Invest 1987; 80: 1280-8.
    • (1987) J. Clin. Invest. , vol.80 , pp. 1280-1288
    • Clark, S.D.1    Kobayashi, D.K.2    Welgus, H.G.3
  • 187
    • 0035190512 scopus 로고    scopus 로고
    • Retinoic acid attenuates cytokine-driven fibroblast degradation of extracellular matrix in three-dimensional culture
    • Zhu YK, Liu X, Ertl RF, et al. Retinoic acid attenuates cytokine-driven fibroblast degradation of extracellular matrix in three-dimensional culture. Am J Respir Cell Mol Biol 2001; 25: 620-7.
    • (2001) Am. J. Respir. Cell Mol. Biol. , vol.25 , pp. 620-627
    • Zhu, Y.K.1    Liu, X.2    Ertl, R.F.3
  • 188
    • 0035318252 scopus 로고    scopus 로고
    • All trans-retinoic acid selectively down-regulates matrix metalloproteinase-9 (MMP-9) and up-regulates tissue inhibitor of metalloproteinase-1 (TIMP-1) in human bronchoalveolar lavage cells
    • Frankenberger M, Hauck RW, Frankenberger B, et al. All trans-retinoic acid selectively down-regulates matrix metalloproteinase-9 (MMP-9) and up-regulates tissue inhibitor of metalloproteinase-1 (TIMP-1) in human bronchoalveolar lavage cells. Mol Med 2001; 7: 263-70.
    • (2001) Mol. Med. , vol.7 , pp. 263-270
    • Frankenberger, M.1    Hauck, R.W.2    Frankenberger, B.3
  • 189
    • 0034956885 scopus 로고    scopus 로고
    • Retinoic acids reduce matrilysin (matrix metalloproteinase 7) and inhibit tumor cell invasion in human colon cancer
    • Adachi Y, Itoh F, Yamamoto H, et al. Retinoic acids reduce matrilysin (matrix metalloproteinase 7) and inhibit tumor cell invasion in human colon cancer. Tumour Biol 2001; 22: 247-53.
    • (2001) Tumour Biol. , vol.22 , pp. 247-253
    • Adachi, Y.1    Itoh, F.2    Yamamoto, H.3
  • 190
  • 191
    • 0035260470 scopus 로고    scopus 로고
    • Retinoic acid and extracellular matrix inhibition of matrix metalloproteinase 9 expression is mediated by the mitogen activated protein kinase pathway
    • Tsang KJ, Crowe DL. Retinoic acid and extracellular matrix inhibition of matrix metalloproteinase 9 expression is mediated by the mitogen activated protein kinase pathway. Int J Oncol 2001; 18: 369-74.
    • (2001) Int. J. Oncol. , vol.18 , pp. 369-374
    • Tsang, K.J.1    Crowe, D.L.2
  • 192
    • 0024740707 scopus 로고
    • Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers
    • Luscher B, Mitchell PJ, Williams T, Tjian R. Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers. Genes Dev 1989; 3: 1507-17.
    • (1989) Genes Dev. , vol.3 , pp. 1507-1517
    • Luscher, B.1    Mitchell, P.J.2    Williams, T.3    Tjian, R.4
  • 193
    • 0024367605 scopus 로고
    • Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells
    • Hosler BA, LaRosa GJ, Grippo JF, Gudas LJ. Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells. Mol Cell Biol 1989; 9: 5623-9.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 5623-5629
    • Hosler, B.A.1    LaRosa, G.J.2    Grippo, J.F.3    Gudas, L.J.4
  • 194
    • 0026068274 scopus 로고
    • The transcription factor, Egr-1, is rapidly modulated in response to retinoic acid in P19 embryonal carcinoma cells
    • Edwards SA, Darland T, Sosnowski R, Samuels M, Adamson ED. The transcription factor, Egr-1, is rapidly modulated in response to retinoic acid in P19 embryonal carcinoma cells. Dev Biol 1991; 148: 165-73.
    • (1991) Dev. Biol. , vol.148 , pp. 165-173
    • Edwards, S.A.1    Darland, T.2    Sosnowski, R.3    Samuels, M.4    Adamson, E.D.5
  • 195
    • 0025944877 scopus 로고
    • In vivo regulation of Zif268 messenger RNA expression by 17 beta-estradiol in the rat uterus
    • Suva LJ, Harm SC, Gardner RM, Thiede MA. In vivo regulation of Zif268 messenger RNA expression by 17 beta-estradiol in the rat uterus. Mol Endocrinol 1991; 5: 829-35.
    • (1991) Mol. Endocrinol. , vol.5 , pp. 829-835
    • Suva, L.J.1    Harm, S.C.2    Gardner, R.M.3    Thiede, M.A.4
  • 197
    • 0033794086 scopus 로고    scopus 로고
    • Immunocytochemical detection of the homeobox B3, B4, and C6 gene products in breast carcinomas
    • Bodey B, Bodey B Jr., Siegel SE, Kaiser HE. Immunocytochemical detection of the homeobox B3, B4, and C6 gene products in breast carcinomas. Anticancer Res 2000; 20: 3281-6.
    • (2000) Anticancer Res. , vol.20 , pp. 3281-3286
    • Bodey, B.1    Bodey B., Jr.2    Siegel, S.E.3    Kaiser, H.E.4
  • 198
    • 0034702232 scopus 로고    scopus 로고
    • Compromised HOXA5 function can limit p53 expression in human breast tumours
    • Raman V, Martensen SA, Reisman D, et al. Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature 2000; 405: 974-8.
    • (2000) Nature , vol.405 , pp. 974-978
    • Raman, V.1    Martensen, S.A.2    Reisman, D.3
  • 199
    • 0033145082 scopus 로고    scopus 로고
    • RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid
    • Folberg A, Nagy Kovacs E, Luo J, Giguere V, Featherstone MS. RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid. Dev Dyn 1999; 215: 96-107.
    • (1999) Dev. Dyn. , vol.215 , pp. 96-107
    • Folberg, A.1    Nagy Kovacs, E.2    Luo, J.3    Giguere, V.4    Featherstone, M.S.5
  • 200
    • 0033716911 scopus 로고    scopus 로고
    • Hoxa-5 in mouse developing lung: Cell-specific expression and retinoic acid regulation
    • Kim C, Nielsen HC. Hoxa-5 in mouse developing lung: cell-specific expression and retinoic acid regulation. Am J Physiol Lung Cell Mol Physiol 2000; 279: L863-71.
    • (2000) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.279
    • Kim, C.1    Nielsen, H.C.2
  • 201
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 1996; 271: 12687-90.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12687-12690
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5    Ashkenazi, A.6
  • 202
    • 0036260386 scopus 로고    scopus 로고
    • Decryption of the retinoid death code in leukemia
    • Altucci L, Gronemeyer H. Decryption of the retinoid death code in leukemia. J Clin Immunol 2002; 22: 117-23.
    • (2002) J. Clin. Immunol. , vol.22 , pp. 117-123
    • Altucci, L.1    Gronemeyer, H.2
  • 203
    • 0034961181 scopus 로고    scopus 로고
    • Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL
    • Altucci L, Rossin A, Raffelsberger W, Reitmair A, Chomienne C, Gronemeyer H. Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL. Nat Med 2001; 7: 680-6.
    • (2001) Nat. Med. , vol.7 , pp. 680-686
    • Altucci, L.1    Rossin, A.2    Raffelsberger, W.3    Reitmair, A.4    Chomienne, C.5    Gronemeyer, H.6
  • 204
    • 0035796001 scopus 로고    scopus 로고
    • TRAIL leads to apoptosis in acute promyelocytic leukaemia
    • Bradbury J. TRAIL leads to apoptosis in acute promyelocytic leukaemia. Lancet 2001; 357: 1770.
    • (2001) Lancet , vol.357 , pp. 1770
    • Bradbury, J.1
  • 205
    • 0034671314 scopus 로고    scopus 로고
    • Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) through up-regulation of TRAIL receptors in human lung cancer cells
    • Sun SY, Yue P, Hong WK, Lotan R. Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) through up-regulation of TRAIL receptors in human lung cancer cells. Cancer Res 2000; 60: 7149-55.
    • (2000) Cancer Res. , vol.60 , pp. 7149-7155
    • Sun, S.Y.1    Yue, P.2    Hong, W.K.3    Lotan, R.4
  • 206
    • 0034648696 scopus 로고    scopus 로고
    • Implication of multiple mechanisms in apoptosis induced by the synthetic retinoid CD437 in human prostate carcinoma cells
    • Sun SY, Yue P, Lotan R. Implication of multiple mechanisms in apoptosis induced by the synthetic retinoid CD437 in human prostate carcinoma cells. Oncogene 2000; 19: 4513-22.
    • (2000) Oncogene , vol.19 , pp. 4513-4522
    • Sun, S.Y.1    Yue, P.2    Lotan, R.3
  • 207
    • 9344247476 scopus 로고    scopus 로고
    • Genetic progression model for head and neck cancer: Implications for field cancerization
    • Califano J, van der Riet P, Westra W, et al. Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res 1996; 56: 2488-92.
    • (1996) Cancer Res. , vol.56 , pp. 2488-2492
    • Califano, J.1    van der Riet, P.2    Westra, W.3
  • 208
    • 0032167474 scopus 로고    scopus 로고
    • pRb and p16 protein alterations in human oral tumorigenesis
    • Pande P, Mathur M, Shukla NK, Ralhan R. pRb and p16 protein alterations in human oral tumorigenesis. Oral Oncol 1998; 34: 396-403.
    • (1998) Oral Oncol. , vol.34 , pp. 396-403
    • Pande, P.1    Mathur, M.2    Shukla, N.K.3    Ralhan, R.4
  • 209
    • 0030565001 scopus 로고    scopus 로고
    • Expression of programmed cell death regulatory p53 and bcl-2 proteins in oral lesions
    • Ravi D, Nalinakumari KR, Rajaram RS, Nair MK, Pillai MR. Expression of programmed cell death regulatory p53 and bcl-2 proteins in oral lesions. Cancer Lett 1996; 105: 139-46.
    • (1996) Cancer Lett. , vol.105 , pp. 139-146
    • Ravi, D.1    Nalinakumari, K.R.2    Rajaram, R.S.3    Nair, M.K.4    Pillai, M.R.5
  • 210
    • 0028106313 scopus 로고
    • Overexpression of p53 protein in betel- and tobacco-related human oral dysplasia and squamous-cell carcinoma in India
    • Kaur J, Srivastava A, Ralhan R. Overexpression of p53 protein in betel- and tobacco-related human oral dysplasia and squamous-cell carcinoma in India. Int J Cancer 1994; 58: 340-5.
    • (1994) Int. J. Cancer , vol.58 , pp. 340-345
    • Kaur, J.1    Srivastava, A.2    Ralhan, R.3
  • 211
    • 0032185605 scopus 로고    scopus 로고
    • Co-overexpression of p53 and c-myc proteins linked with advanced stages of betel- and tobacco-related oral squamous cell carcinomas from eastern India
    • Baral R, Patnaik S, Das BR. Co-overexpression of p53 and c-myc proteins linked with advanced stages of betel- and tobacco-related oral squamous cell carcinomas from eastern India. Eur J Oral Sci 1998; 106: 907-13.
    • (1998) Eur. J. Oral Sci. , vol.106 , pp. 907-913
    • Baral, R.1    Patnaik, S.2    Das, B.R.3
  • 212
    • 0028999007 scopus 로고
    • High prevalence of expression of p53 oncoprotein in oral carcinomas from India associated with betel and tobacco chewing
    • Kuttan NA, Rosin MP, Ambika K, Priddy RW, Bhakthan NM, Zhang L. High prevalence of expression of p53 oncoprotein in oral carcinomas from India associated with betel and tobacco chewing. Eur J Cancer B Oral Oncol 1995; 31 B: 169-73.
    • (1995) Eur. J. Cancer B Oral. Oncol. , vol.31 B , pp. 169-173
    • Kuttan, N.A.1    Rosin, M.P.2    Ambika, K.3    Priddy, R.W.4    Bhakthan, N.M.5    Zhang, L.6
  • 213
    • 0031873404 scopus 로고    scopus 로고
    • Prognostic significance of p53 protein overexpression in betel- and tobacco-related oral oncogenesis
    • Kaur J, Srivastava A, Ralhan R. Prognostic significance of p53 protein overexpression in betel- and tobacco-related oral oncogenesis. Int J Cancer 1998; 79: 370-5.
    • (1998) Int. J. Cancer , vol.79 , pp. 370-375
    • Kaur, J.1    Srivastava, A.2    Ralhan, R.3
  • 214
    • 0036317581 scopus 로고    scopus 로고
    • Prognostic factors in betel and tobacco related oral cancer
    • Pande P, Soni S, Kaur J, et al. Prognostic factors in betel and tobacco related oral cancer. Oral Oncol 2002; 38: 491-9.
    • (2002) Oral Oncol. , vol.38 , pp. 491-499
    • Pande, P.1    Soni, S.2    Kaur, J.3
  • 215
    • 0034741236 scopus 로고    scopus 로고
    • Differential expression of retinoic acid receptors and p53 protein in normal, premalignant, and malignant esophageal tissues
    • Zhang W, Rashid A, Wu H, Xu XC. Differential expression of retinoic acid receptors and p53 protein in normal, premalignant, and malignant esophageal tissues. J Cancer Res Clin Oncol 2001; 127: 237-42.
    • (2001) J. Cancer Res. Clin. Oncol. , vol.127 , pp. 237-242
    • Zhang, W.1    Rashid, A.2    Wu, H.3    Xu, X.C.4
  • 216
    • 0037538589 scopus 로고    scopus 로고
    • Retinoic acid receptor-alpha as a prognostic indicator in oral squamous cell carcinoma
    • (in Press)
    • Charkravarti N, Mathur M, Bahadur S, Shukla NK, Ralhan R. Retinoic acid receptor-alpha as a prognostic indicator in oral squamous cell carcinoma. Int J Cancer 2002 (in Press).
    • (2002) Int. J. Cancer
    • Charkravarti, N.1    Mathur, M.2    Bahadur, S.3    Shukla, N.K.4    Ralhan, R.5
  • 217
    • 0030988737 scopus 로고    scopus 로고
    • Accumulation of p53 protein and retinoic acid receptor beta in retinoid chemoprevention
    • Shin DM, Xu XC, Lippman SM, et al. Accumulation of p53 protein and retinoic acid receptor beta in retinoid chemoprevention. Clin Cancer Res 1997; 3: 875-80.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 875-880
    • Shin, D.M.1    Xu, X.C.2    Lippman, S.M.3
  • 218
    • 0035109499 scopus 로고    scopus 로고
    • Overexpression of retinoic acid receptor beta induces growth arrest and apoptosis in oral cancer cell lines
    • Hayashi K, Yokozaki H, Naka K, Yasui W, Lotan R, Tahara E. Overexpression of retinoic acid receptor beta induces growth arrest and apoptosis in oral cancer cell lines. Jpn J Cancer Res 2001; 92: 42-50.
    • (2001) Jpn. J. Cancer Res. , vol.92 , pp. 42-50
    • Hayashi, K.1    Yokozaki, H.2    Naka, K.3    Yasui, W.4    Lotan, R.5    Tahara, E.6
  • 219
    • 0032514374 scopus 로고    scopus 로고
    • Favorable prognostic significance of high-level retinoic acid receptor beta expression in neuroblastoma mediated by effects on cell cycle regulation
    • Cheung B, Hocker JE, Smith SA, Norris MD, Haber M, Marshall GM. Favorable prognostic significance of high-level retinoic acid receptor beta expression in neuroblastoma mediated by effects on cell cycle regulation. Oncogene 1998; 17: 751-9.
    • (1998) Oncogene , vol.17 , pp. 751-759
    • Cheung, B.1    Hocker, J.E.2    Smith, S.A.3    Norris, M.D.4    Haber, M.5    Marshall, G.M.6
  • 220
    • 0035799528 scopus 로고    scopus 로고
    • Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function
    • Curtin JC, Dragnev KH, Sekula D, Christie AJ, Dmitrovsky E, Spinella MJ. Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function. Oncogene 2001; 20: 2559-69.
    • (2001) Oncogene , vol.20 , pp. 2559-2569
    • Curtin, J.C.1    Dragnev, K.H.2    Sekula, D.3    Christie, A.J.4    Dmitrovsky, E.5    Spinella, M.J.6
  • 221
    • 0035571564 scopus 로고    scopus 로고
    • Modulation of Ki67, p53 and RARbeta expression in normal, premalignant and malignant human oral epithelial cells by chemopreventive agents
    • D'Ambrosio SM, Gibson-D'Ambrosio RE, Wani G, et al. Modulation of Ki67, p53 and RARbeta expression in normal, premalignant and malignant human oral epithelial cells by chemopreventive agents. Anticancer Res 2001; 21: 3229-35.
    • (2001) Anticancer Res. , vol.21 , pp. 3229-3235
    • D'Ambrosio, S.M.1    Gibson-D'Ambrosio, R.E.2    Wani, G.3
  • 222
    • 0034903213 scopus 로고    scopus 로고
    • All-trans-retinoic acid enhances the effect of adenovirus-mediated wild-type p53 gene transfer in head and neck squamous cell carcinoma
    • Nakashima T, Sun SY, Lotan R, et al. All-trans-retinoic acid enhances the effect of adenovirus-mediated wild-type p53 gene transfer in head and neck squamous cell carcinoma. Laryngoscope 2001; 111: 1459-64.
    • (2001) Laryngoscope , vol.111 , pp. 1459-1464
    • Nakashima, T.1    Sun, S.Y.2    Lotan, R.3
  • 223
    • 85047697085 scopus 로고    scopus 로고
    • Cell cycle genes as targets of retinoid induced ovarian tumor cell growth suppression
    • Zhang D, Vuocolo S, Masciullo V, et al. Cell cycle genes as targets of retinoid induced ovarian tumor cell growth suppression. Oncogene 2001; 20: 7935-44.
    • (2001) Oncogene , vol.20 , pp. 7935-7944
    • Zhang, D.1    Vuocolo, S.2    Masciullo, V.3
  • 224
    • 0034646895 scopus 로고    scopus 로고
    • Effect of 9-cisretinoic acid on oral squamous cell carcinoma cell lines
    • Hayashi K, Yokozaki H, Naka K, et al. Effect of 9-cisretinoic acid on oral squamous cell carcinoma cell lines. Cancer Lett 2000; 151: 199-208.
    • (2000) Cancer Lett. , vol.151 , pp. 199-208
    • Hayashi, K.1    Yokozaki, H.2    Naka, K.3
  • 225
    • 0028983107 scopus 로고
    • p53 independent G0/G1 arrest and apoptosis induced by a novel retinoid in human breast cancer cells
    • Shao ZM, Dawson MI, Li XS, et al. p53 independent G0/G1 arrest and apoptosis induced by a novel retinoid in human breast cancer cells. Oncogene 1995; 11: 493-504.
    • (1995) Oncogene , vol.11 , pp. 493-504
    • Shao, Z.M.1    Dawson, M.I.2    Li, X.S.3
  • 226
    • 0032757641 scopus 로고    scopus 로고
    • Inhibition of myeloma cell growth by all-trans retinoic acid is associated with upregulation of p21WAF1 and dephosphorylation of the retinoblastoma protein
    • Lavelle D, Chen YH, Hankewych M, Desimone J. Inhibition of myeloma cell growth by all-trans retinoic acid is associated with upregulation of p21WAF1 and dephosphorylation of the retinoblastoma protein. Leuk Lymphoma 1999; 35: 261-8.
    • (1999) Leuk. Lymphoma , vol.35 , pp. 261-268
    • Lavelle, D.1    Chen, Y.H.2    Hankewych, M.3    Desimone, J.4
  • 227
    • 0033557347 scopus 로고    scopus 로고
    • Synthetic retinoid CD437 induces S-phase arrest and apoptosis in human prostate cancer cells LNCaP and PC-3
    • Liang JY, Fontana JA, Rao JN, et al. Synthetic retinoid CD437 induces S-phase arrest and apoptosis in human prostate cancer cells LNCaP and PC-3. Prostate 1999; 38: 228-36.
    • (1999) Prostate , vol.38 , pp. 228-236
    • Liang, J.Y.1    Fontana, J.A.2    Rao, J.N.3
  • 228
    • 0025861828 scopus 로고
    • Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection
    • Choi K, Frommel TO, Stern RK, et al. Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection. Proc Natl Acad Sci USA 1991; 88: 7386-90.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7386-7390
    • Choi, K.1    Frommel, T.O.2    Stern, R.K.3
  • 230
    • 0030916142 scopus 로고    scopus 로고
    • Differential expression of multidrug resistance gene product, P-glycoprotein, in normal, dysplastic and malignant oral mucosa in India
    • Jain V, Das SN, Luthra K, Shukla NK, Ralhan R. Differential expression of multidrug resistance gene product, P-glycoprotein, in normal, dysplastic and malignant oral mucosa in India. Int J Cancer 1997; 74: 128-33.
    • (1997) Int. J. Cancer , vol.74 , pp. 128-133
    • Jain, V.1    Das, S.N.2    Luthra, K.3    Shukla, N.K.4    Ralhan, R.5
  • 231
    • 0032940138 scopus 로고    scopus 로고
    • P-glycoprotein is positively correlated with p53 in human oral pre-malignant and malignant lesions and is associated with poor prognosis
    • Ralhan R, Swain RK, Agarwal S, et al. P-glycoprotein is positively correlated with p53 in human oral pre-malignant and malignant lesions and is associated with poor prognosis. Int J Cancer 1999; 84: 80-5.
    • (1999) Int. J. Cancer , vol.84 , pp. 80-85
    • Ralhan, R.1    Swain, R.K.2    Agarwal, S.3
  • 233
    • 0035895894 scopus 로고    scopus 로고
    • Aromatic hydrocarbon receptor (AhR).AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells
    • Mathieu MC, Lapierre I, Brault K, Raymond M. Aromatic hydrocarbon receptor (AhR).AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells. J Biol Chem 2001; 276: 4819-27.
    • (2001) J. Biol. Chem. , vol.276 , pp. 4819-4827
    • Mathieu, M.C.1    Lapierre, I.2    Brault, K.3    Raymond, M.4
  • 235
    • 0033903436 scopus 로고    scopus 로고
    • Induction of MDM2-P2 transcripts correlates with stabilized wild-type p53 in betel- and tobacco-related human oral cancer
    • Ralhan R, Sandhya A, Meera M, Bohdan W, Nootan SK. Induction of MDM2-P2 transcripts correlates with stabilized wild-type p53 in betel- and tobacco-related human oral cancer. Am J Pathol 2000; 157: 587-96.
    • (2000) Am. J. Pathol. , vol.157 , pp. 587-596
    • Ralhan, R.1    Sandhya, A.2    Meera, M.3    Bohdan, W.4    Nootan, S.K.5
  • 237
    • 0003060912 scopus 로고
    • Retinoids and cancer in experimental animals
    • Sporn MB, Roberts AB, Goodman DS, eds. second edition. New York, NY: Raven Press Ltd
    • Moon RC, Mehta RG, Rao KVN. Retinoids and cancer in experimental animals. In: Sporn MB, Roberts AB, Goodman DS, eds. The retinoids: biology, chemistry, and medicine, second edition. New York, NY: Raven Press Ltd., 1994; 573-95.
    • (1994) The Retinoids: Biology, Chemistry, and Medicine , pp. 573-595
    • Moon, R.C.1    Mehta, R.G.2    Rao, K.V.N.3
  • 238
    • 0023944920 scopus 로고
    • Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes
    • Reddel RR, Ke Y, Gerwin BI, et al. Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes. Cancer Res 1988; 48: 1904-9.
    • (1988) Cancer Res. , vol.48 , pp. 1904-1909
    • Reddel, R.R.1    Ke, Y.2    Gerwin, B.I.3
  • 239
    • 0022547592 scopus 로고
    • Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma
    • Dejean A, Bougueleret L, Grzeschik KH, Tiollais P. Hepatitis B virus DNA integration in a sequence homologous to v-erb-A and steroid receptor genes in a hepatocellular carcinoma. Nature 1986; 322: 70-2.
    • (1986) Nature , vol.322 , pp. 70-72
    • Dejean, A.1    Bougueleret, L.2    Grzeschik, K.H.3    Tiollais, P.4
  • 240
    • 0023923136 scopus 로고
    • Identification of a second human retinoic acid receptor
    • Brand N, Petkovich M, Krust A, et al. Identification of a second human retinoic acid receptor. Nature 1988; 332: 850-3.
    • (1988) Nature , vol.332 , pp. 850-853
    • Brand, N.1    Petkovich, M.2    Krust, A.3
  • 241
    • 0023637278 scopus 로고
    • Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer
    • Kok K, Osinga J, Carritt B, et al. Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer. Nature 1987; 330: 578-81.
    • (1987) Nature , vol.330 , pp. 578-581
    • Kok, K.1    Osinga, J.2    Carritt, B.3
  • 242
    • 84989611379 scopus 로고
    • Tissue changes following deprivation of fat-soluble vitamin A
    • Wolbach SB, Howe PR. Tissue changes following deprivation of fat-soluble vitamin A. J Exp Med 1925; 42: 753-7.
    • (1925) J. Exp. Med. , vol.42 , pp. 753-757
    • Wolbach, S.B.1    Howe, P.R.2
  • 244
    • 0028145695 scopus 로고
    • Topical tretinoin in the treatment of lichen planus and leukoplakia of the mouth mucosa. A clinical evaluation
    • Boisnic S, Branchet MC, Pascal F, Ben Slama L, Rostin M, Szpirglas H. Topical tretinoin in the treatment of lichen planus and leukoplakia of the mouth mucosa. A clinical evaluation. Ann Dermatol Venereol 1994; 121: 459-63.
    • (1994) Ann. Dermatol. Venereol. , vol.121 , pp. 459-463
    • Boisnic, S.1    Branchet, M.C.2    Pascal, F.3    Ben Slama, L.4    Rostin, M.5    Szpirglas, H.6
  • 245
    • 0028074937 scopus 로고
    • Topical tretinoin in the treatment of lichen planus and leukoplakia of the oral mucosa. A biochemical evaluation of the keratinization
    • Branchet MC, Boisnic S, Pascal F, Ben Slama L, Rostin M, Szpirglas H. Topical tretinoin in the treatment of lichen planus and leukoplakia of the oral mucosa. A biochemical evaluation of the keratinization. Ann Dermatol Venereol 1994; 121: 464-9.
    • (1994) Ann. Dermatol. Venereol. , vol.121 , pp. 464-469
    • Branchet, M.C.1    Boisnic, S.2    Pascal, F.3    Ben Slama, L.4    Rostin, M.5    Szpirglas, H.6
  • 247
    • 0025304643 scopus 로고
    • The effect of topical tretinoin on dysplastic nevi. A preliminary trial
    • Edwards L, Jaffe P. The effect of topical tretinoin on dysplastic nevi. A preliminary trial. Arch Dermatol 1990; 126: 494-9.
    • (1990) Arch. Dermatol. , vol.126 , pp. 494-499
    • Edwards, L.1    Jaffe, P.2
  • 248
  • 250
    • 0028945382 scopus 로고
    • Beneficial effect of low-dose systemic retinoid in combination with topical tretinoin for the treatment and prophylaxis of premalignant and malignant skin lesions in renal transplant recipients
    • Rook AH, Jaworsky C, Nguyen T, et al. Beneficial effect of low-dose systemic retinoid in combination with topical tretinoin for the treatment and prophylaxis of premalignant and malignant skin lesions in renal transplant recipients. Transplantation 1995; 59: 714-9.
    • (1995) Transplantation , vol.59 , pp. 714-719
    • Rook, A.H.1    Jaworsky, C.2    Nguyen, T.3
  • 253
    • 0027395951 scopus 로고
    • Comparison of low-dose isotretinoin with beta carotene to prevent oral carcinogenesis
    • Lippman SM, Batsakis JG, Toth BB, et al. Comparison of low-dose isotretinoin with beta carotene to prevent oral carcinogenesis. N Engl J Med 1993; 328: 15-20.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 15-20
    • Lippman, S.M.1    Batsakis, J.G.2    Toth, B.B.3
  • 254
    • 10244243723 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor expression in metaplastic bronchial epithelium
    • Kurie JM, Shin HJ, Lee JS, et al. Increased epidermal growth factor receptor expression in metaplastic bronchial epithelium. Clin Cancer Res 1996; 2: 1787-93.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 1787-1793
    • Kurie, J.M.1    Shin, H.J.2    Lee, J.S.3
  • 255
    • 0030988737 scopus 로고    scopus 로고
    • Accumulation of p53 protein and retinoic acid receptor beta in retinoid chemoprevention
    • Shin DM, Xu XC, Lippman SM, et al. Accumulation of p53 protein and retinoic acid receptor beta in retinoid chemoprevention. Clin Cancer Res 1997; 3: 875-80.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 875-880
    • Shin, D.M.1    Xu, X.C.2    Lippman, S.M.3
  • 256
    • 0032847979 scopus 로고    scopus 로고
    • Transforming growth factor alpha (TGF-alpha) expression in dysplastic oral leukoplakia: Modulation by 13-cis retinoic acid
    • Beenken SW, Sellers MT, Huang P, et al. Transforming growth factor alpha (TGF-alpha) expression in dysplastic oral leukoplakia: modulation by 13-cis retinoic acid. Head Neck 1999; 21: 566-73.
    • (1999) Head Neck , vol.21 , pp. 566-573
    • Beenken, S.W.1    Sellers, M.T.2    Huang, P.3
  • 257
    • 0343091242 scopus 로고    scopus 로고
    • Predicting cancer development in oral leukoplakia: Ten years of translational research
    • Lee JJ, Hong WK, Hittelman WN, et al. Predicting cancer development in oral leukoplakia: ten years of translational research. Clin Cancer Res 2000; 6: 1702-10.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1702-1710
    • Lee, J.J.1    Hong, W.K.2    Hittelman, W.N.3
  • 258
    • 0027105202 scopus 로고
    • Chemoprevention of skin cancer in xeroderma pigmentosum
    • Kraemer KH, DiGiovanna JJ, Peck GL. Chemoprevention of skin cancer in xeroderma pigmentosum. J Dermatol 1992; 19: 715-8.
    • (1992) J. Dermatol. , vol.19 , pp. 715-718
    • Kraemer, K.H.1    DiGiovanna, J.J.2    Peck, G.L.3
  • 259
    • 0028280222 scopus 로고
    • Randomized placebo-controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia
    • Lee JS, Lippman SM, Benner SE, et al. Randomized placebo-controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia. J Clin Oncol 1994; 12: 937-45.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 937-945
    • Lee, J.S.1    Lippman, S.M.2    Benner, S.E.3
  • 260
    • 0027224034 scopus 로고
    • Fenretinide (4-HPR) in chemoprevention of oral leukoplakia
    • Chiesa F, Tradati N, Marazza M, et al. Fenretinide (4-HPR) in chemoprevention of oral leukoplakia. J Cell Biochem Suppl 1993; 17F: 255-61.
    • (1993) J. Cell Biochem. Suppl. , vol.17 F , pp. 255-261
    • Chiesa, F.1    Tradati, N.2    Marazza, M.3
  • 261
    • 0028036249 scopus 로고
    • Successful topical treatment of oral lichen planus and leukoplakias with fenretinide (4-HPR)
    • Tradati N, Chiesa F, Rossi N, et al. Successful topical treatment of oral lichen planus and leukoplakias with fenretinide (4-HPR). Cancer Lett 1994; 76: 109-11.
    • (1994) Cancer Lett. , vol.76 , pp. 109-111
    • Tradati, N.1    Chiesa, F.2    Rossi, N.3
  • 262
    • 0033875561 scopus 로고    scopus 로고
    • N-(4-hydroxyphenyl) retinamide in the chemoprevention of squamous metaplasia and dysplasia of the bronchial epithelium
    • Kurie JM, Lee JS, Khuri FR, et al. N-(4-hydroxyphenyl) retinamide in the chemoprevention of squamous metaplasia and dysplasia of the bronchial epithelium. Clin Cancer Res 2000; 6: 2973-9.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2973-2979
    • Kurie, J.M.1    Lee, J.S.2    Khuri, F.R.3
  • 263
    • 0035868837 scopus 로고    scopus 로고
    • Safety of the synthetic retinoid fenretinide: Long-term results from a controlled clinical trial for the prevention of contralateral breast cancer
    • Camerini T, Mariani L, De Palo G, et al. Safety of the synthetic retinoid fenretinide: long-term results from a controlled clinical trial for the prevention of contralateral breast cancer. J Clin Oncol 2001; 19: 1664-70.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 1664-1670
    • Camerini, T.1    Mariani, L.2    De Palo, G.3
  • 264
    • 0035319763 scopus 로고    scopus 로고
    • Bayesian monitoring of a phase 2 chemoprevention trial in high-risk cohorts for prostate cancer
    • Weiss HL, Urban DA, Grizzle WE, et al. Bayesian monitoring of a phase 2 chemoprevention trial in high-risk cohorts for prostate cancer. Urology 2001; 57: 220-3.
    • (2001) Urology , vol.57 , pp. 220-223
    • Weiss, H.L.1    Urban, D.A.2    Grizzle, W.E.3
  • 265
    • 0038692733 scopus 로고    scopus 로고
    • Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial
    • Omenn GS, Goodman GE, Thomquist MD, et al. Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J Natl Cancer Inst 1996; 88: 1550-9.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 1550-1559
    • Omenn, G.S.1    Goodman, G.E.2    Thomquist, M.D.3
  • 266
    • 0029686917 scopus 로고    scopus 로고
    • Chemoprevention of lung cancer: The beta-Carotene and Retinol Efficacy Trial (CARET) in high-risk smokers and as bestos-exposed workers
    • Omenn GS, Goodman G, Thornquist M, et al. Chemoprevention of lung cancer: the beta-Carotene and Retinol Efficacy Trial (CARET) in high-risk smokers and as bestos-exposed workers. IARC Sci Publ 1996; 136: 67-85.
    • (1996) IARC Sci. Publ. , vol.136 , pp. 67-85
    • Omenn, G.S.1    Goodman, G.2    Thornquist, M.3
  • 267
    • 10344238570 scopus 로고    scopus 로고
    • Alphatocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, betacarotene cancer prevention study: Effects of base-line characteristics and study compliance
    • Albanes D, Heinonen OP, Taylor PR, et al. Alphatocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, betacarotene cancer prevention study: effects of base-line characteristics and study compliance. J Natl Cancer Inst 1996; 88: 1560-70.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 1560-1570
    • Albanes, D.1    Heinonen, O.P.2    Taylor, P.R.3
  • 269
    • 0028812859 scopus 로고
    • Adjuvant treatment with a vitamin A analogue (etretinate) after transurethral resection of superficial bladder tumors. Final analysis of a prospective, randomized multicenter trial in Switzerland
    • Studer UE, Jenzer S, Biedermann C, et al. Adjuvant treatment with a vitamin A analogue (etretinate) after transurethral resection of superficial bladder tumors. Final analysis of a prospective, randomized multicenter trial in Switzerland. Eur Urol 1995; 28: 284-90.
    • (1995) Eur. Urol. , vol.28 , pp. 284-290
    • Studer, U.E.1    Jenzer, S.2    Biedermann, C.3
  • 270
    • 0026559655 scopus 로고
    • Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia
    • Miller WH Jr, Kakizuka A, Frankel SR, et al. Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia. Proc Natl Acad Sci USA 1992; 89: 2694-8.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2694-2698
    • Miller W.H., Jr.1    Kakizuka, A.2    Frankel, S.R.3
  • 271
    • 0025271098 scopus 로고
    • Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha)
    • Collins SJ, Robertson KA, Mueller L. Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha). Mol Cell Biol 1990; 10: 2154-63.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 2154-2163
    • Collins, S.J.1    Robertson, K.A.2    Mueller, L.3
  • 272
    • 0032474851 scopus 로고    scopus 로고
    • Specific retinoid receptors cooperate to signal growth suppression and maturation of human embryonal carcinoma cells
    • Spinella MJ, Kitareewan S, Mellado B, Sekula D, Khoo KS, Dmitrovsky E. Specific retinoid receptors cooperate to signal growth suppression and maturation of human embryonal carcinoma cells. Oncogene 1998; 16: 3471-80.
    • (1998) Oncogene , vol.16 , pp. 3471-3480
    • Spinella, M.J.1    Kitareewan, S.2    Mellado, B.3    Sekula, D.4    Khoo, K.S.5    Dmitrovsky, E.6
  • 273
    • 0027535564 scopus 로고
    • Tumor-suppressive effect of the retinoic acid receptor beta in human epidermoid lung cancer cells
    • Houle B, Rochette-Egly C, Bradley WE. Tumor-suppressive effect of the retinoic acid receptor beta in human epidermoid lung cancer cells. Proc Natl Acad Sci USA 1993; 90: 985-9.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 985-989
    • Houle, B.1    Rochette-Egly, C.2    Bradley, W.E.3
  • 274
    • 0029590158 scopus 로고
    • Growth suppression of transformed human bronchial epithelial cells by all-trans-retinoic acid occurs through specific retinoid receptors
    • Ahn MJ, Langenfeld J, Moasser MM, Rusch V, Dmitrovsky E. Growth suppression of transformed human bronchial epithelial cells by all-trans-retinoic acid occurs through specific retinoid receptors. Oncogene 1995; 11: 2357-64.
    • (1995) Oncogene , vol.11 , pp. 2357-2364
    • Ahn, M.J.1    Langenfeld, J.2    Moasser, M.M.3    Rusch, V.4    Dmitrovsky, E.5
  • 275
    • 0027275148 scopus 로고
    • Nutrition intervention trials in Linxian, China: Supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population
    • Blot WJ, Li JY, Taylor PR, et al. Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. J Natl Cancer Inst 1993; 85: 1483-92.
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 1483-1492
    • Blot, W.J.1    Li, J.Y.2    Taylor, P.R.3
  • 276
    • 0027182552 scopus 로고
    • Nutrition intervention trials in Linxian, China: Multiple vitamin/mineral supplementation, cancer incidence, and disease-specific mortality among adults with esophageal dysplasia
    • Li JY, Taylor PR, Li B, et al. Nutrition intervention trials in Linxian, China: multiple vitamin/mineral supplementation, cancer incidence, and disease-specific mortality among adults with esophageal dysplasia. J Natl Cancer Inst 1993; 85: 1492-8.
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 1492-1498
    • Li, J.Y.1    Taylor, P.R.2    Li, B.3
  • 277
    • 0028340644 scopus 로고
    • Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: Results from the General Population Trial in Linxian, China
    • Wang GQ, Dawsey SM, Li JY, et al. Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the General Population Trial in Linxian, China. Cancer Epidemiol Biomarkers Prev 1994; 3: 161-6.
    • (1994) Cancer Epidemiol. Biomarkers Prev. , vol.3 , pp. 161-166
    • Wang, G.Q.1    Dawsey, S.M.2    Li, J.Y.3
  • 278
    • 0031394678 scopus 로고    scopus 로고
    • Chemoprevention of cancer of uterine cervix: A study on chemoprevention of retinamide II from cervical precancerous lesions
    • Ruidi C, Aihua D, Peiyu B, et al. Chemoprevention of cancer of uterine cervix: a study on chemoprevention of retinamide II from cervical precancerous lesions. J Cell Biochem Suppl 1997; 28-29: 140-3.
    • (1997) J. Cell Biochem. Suppl. , vol.28-29 , pp. 140-143
    • Ruidi, C.1    Aihua, D.2    Peiyu, B.3
  • 279
    • 0028399097 scopus 로고
    • A study on chemoprevention of retinamide II from cervical precancerous lesions
    • Chen RD, Ding AH, Han R. A study on chemoprevention of retinamide II from cervical precancerous lesions. Zhonghua Yu Fang Yi Xue Za Zhi 1994; 28: 75-7.
    • (1994) Zhonghua Yu Fang Yi Xue Za Zhi , vol.28 , pp. 75-77
    • Chen, R.D.1    Ding, A.H.2    Han, R.3
  • 280
    • 0029097249 scopus 로고
    • Prevention of skin cancer and reduction of keratotic skin lesions during acitretin therapy in renal transplant recipients: A double-blind, placebo-controlled study
    • Bavinck JN, Tieben LM, Van der Woude FJ, et al. Prevention of skin cancer and reduction of keratotic skin lesions during acitretin therapy in renal transplant recipients: a double-blind, placebo-controlled study. J Clin Oncol 1995; 13: 1933-8.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1933-1938
    • Bavinck, J.N.1    Tieben, L.M.2    Van der Woude, F.J.3
  • 281
    • 0031037139 scopus 로고    scopus 로고
    • Retinoic acid-responsive enhancers located 3′ of the Hox A and Hox B homeobox gene clusters. Functional analysis
    • Langston AW, Thompson JR, Gudas LJ. Retinoic acid-responsive enhancers located 3' of the Hox A and Hox B homeobox gene clusters. Functional analysis. J Biol Chem 1997; 272: 2167-75.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2167-2175
    • Langston, A.W.1    Thompson, J.R.2    Gudas, L.J.3
  • 282
    • 0032404102 scopus 로고    scopus 로고
    • Retinoic acid and interferon alpha act synergistically as antiangiogenic and antitumor agents against human head and neck squamous cell carcinoma
    • Lingen MW, Polverini PJ, Bouck NP. Retinoic acid and interferon alpha act synergistically as antiangiogenic and antitumor agents against human head and neck squamous cell carcinoma. Cancer Res 1998; 58: 5551-8.
    • (1998) Cancer Res. , vol.58 , pp. 5551-5558
    • Lingen, M.W.1    Polverini, P.J.2    Bouck, N.P.3
  • 283
    • 0032922598 scopus 로고    scopus 로고
    • Retinoid receptor-dependent and -independent effects of N-(4-hydroxyphenyl)retinamide in F9 embryonal carcinoma cells
    • Clifford JL, Menter DG, Wang M, Lotan R, Lippman SM. Retinoid receptor-dependent and -independent effects of N-(4-hydroxyphenyl)retinamide in F9 embryonal carcinoma cells. Cancer Res 1999; 59: 14-8.
    • (1999) Cancer Res. , vol.59 , pp. 14-18
    • Clifford, J.L.1    Menter, D.G.2    Wang, M.3    Lotan, R.4    Lippman, S.M.5


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