Post-transcriptional regulation of MyD118 and GADD45 in human lung carcinoma cells during 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid-induced apoptosis

Molecular Pharmacology

Volumn 55, Issue 4, 1999, Pages 668-676

  Sakaue, Morito ^b   Adachi, Hiroshi ^a,b   Jetten, Anton M ^b  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; CASPASE; CASPASE INHIBITOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DRUG HALF LIFE; DRUG MECHANISM; ENZYME ACTIVATION; GENE; GENE EXPRESSION; GENE SEQUENCE; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG CARCINOMA; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANTIGENS, DIFFERENTIATION; ANTINEOPLASTIC AGENTS; APOPTOSIS; BASE SEQUENCE; CASPASES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; PROTEIN BIOSYNTHESIS; PROTEINS; RETINOIDS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0032948740     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Abdollahi A, Lord, KA, Hoffman-Liebermann B and Liebermann DA (1991) Sequence and expression of a cDNA encoding MyD118: a novel myeloid differentiation primary response gene induced by multiple cytokines. Oncogene 6:165-167.
2. Adachi H, Adams A, Hughes FM, Zhang J, Cidlowski JA and Jetten AM (1998a) Induction of apoptosis by the novel retinoid AHPN in human T cell lymphoma cells involves caspase-dependent and independent pathways. Cell Death Differ 5:973-983.
3. Adachi H, Preston G, Harvat B, Dawson MI and Jetten AM (1998b) Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma cells. Am J Respir Cell Mol Biol 18:323-333.
4. Buck J, Derguini F, Levi E, Nakanishi K and Hammerling U (1991) Intracellular signaling by 14-hydroxy-4,14-retro-retinol. Science (Wash DC) 254:1654-1656.
5. Chao WR, Hobbs PD, Jong L, Zhang XK, Zheng Y, Wu Q, Shroot B and Dawson MI (1997) Effects of receptor class- and subtype-selective retinoids and an apoptosis-inducing retinoid on the adherent growth of the NIH:OVCAR-3 ovarian cancer cell line in culture. Cancer Lett 115:1-7.
6. Chen CYA and Shyu AB (1995) AU-rich elements: Characterization and importance in mRNA degradation. Trends Biochem Sci 20:465-470.
7. Delescluse C, Cavey MT, Martin B, Bernard BA, Reichert U, Maignan J, Darmon M and Shroot B (1991) Selective high affinity RA receptor α or β-γ ligands. Mol Pharmacol 40:556-562.
8. Fanjul A, Dawson MI, Hobbs PD, Jong L, Cameron JF, Harlev E, Graupner G, Lu XP and Pfahl M (1994) A new class of retinoids with selective inhibition of AP-1 inhibits proliferation. Nature (London) 372:107-111.
9. Fornace AJ (1992) DNA-damage inducible genes in mammalian cells. Annu Rev Genet 26:505-524.
10. Fornace AJ, Nebert DW, Hollander MC, Luethy JD, Papathanasiou M, Fargnoli J and Holbrook NJ (1989) Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents. Mol Cell Biol 9:4196-4203.
11. Geradts J, Chen JY, Russell EK, Yankaskas JR, Nieves L and Minna JD (1993) Human lung cancer cell lines exhibit resistance to retinoic acid treatment. Cell Growth Differ 4:799-809.
12. Giguère V (1994) RA receptors and cellular retinoid binding proteins: Complex interplay in retinoid signaling. Endocr Rev 15:61-79.
13. Hollander MC, Alamo I, Jackman J, Wang MG, McBride OW and Fornace AJJ (1993) Analysis of the mammalian gadd45 gene and its response to DNA damage. J Biol Chem 268:24385-24393.
14. Hsu CK, Rishi AK, Li XS, Dawson MI, Reichert U, Shroot B and Fontana JA (1997a) Bcl-X(L) expression and its downregulation by a novel retinoid in breast carcinoma cells. Exp Cell Res 232:17-24.
15. Hsu CA, Rishi AK, Li XS, Gerald TM, Dawson MI, Schiffer C, Reichert U, Shroot B, Poirer GC and Fontana JA (1997b) Retinoid induced apoptosis in leukemia cells through a retinoic acid nuclear receptor-independent pathway. Blood 89:4470-4479.
16. Kalemkerian GP, Jasti RK, Celano P, Nelkin BD and Mabry M (1994) All-trans-retinoic acid alters myc gene expression and inhibits in vitro progression in small lung cancer. Cell Growth Differ 5:55-60.
17. Kalemkerian GP, Slusher R, Ramalingam S, Gadgeel S and Mabry M (1995) Growth inhibition and induction of apoptosis by fenretinide in small-cell lung cancer cell lines. J Natl Cancer Inst 87:1674-1680.
18. Koonin EV (1997) Cell cycle and apoptosis: Possible roles of Gadd45 and MyD118 proteins inferred from their homology to ribosomal proteins. J Mol Med 75:236-238.
19. Lehmann JM, Jong L, Fanjul A, Cameron JF, Lu XP, Haefner P, Dawson MI and Pfahl M (1992) Retinoids selective for retinoid X receptor response pathways. Science (Wash DC) 258:1944-1946.
20. Liang P, Zhu W, Zhang X, Gao Z, O'Connell RP, Averboukh L, Wang F and Pardee AB (1994) Differential display using one base anchored oligo-dT primers. Nucleic Acids Res 22:5763-5764.
21. Li Y, Lin B, Agadir A, Liu R, Dawson MI, Reed JC, Fontana JA, Bost F, Hobbs PD, Zheng Y, Chen GQ, Shroot B, Mercola D and Zhang XK (1998) Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol 18:4719-4731.
22. Li XS, Rishi AK, Shao ZM, Dawson MI, Jong L, Shroot B, Reichert U, Ordonez J and Fontana JA (1996) Posttranscriptional regulation of p21WAF1/CIP1 expression in human breast carcinoma cells. Cancer Res 56:5055-5062.
23. Lu XP, Fanjul A, Picard N, Pfahl M, Rungta D, Nared-Hood K, Carter B, Piedrafita J, Tang S, Fabbrizio E and Pfahl M (1997) Novel retinoid-related molecules as apoptosis inducers and effective inhibitors of human lung cancer cells in vivo. Nat Med 3:686-690.
24. Mannino DM, Ford E, Giovino GA and Thun M (1998) Lung cancer in the United States from 1979 to 1992: An analysis using multiple-cause mortality data. Int J Epidemiol 27:159-166.
25. Meister B, Fink FM, Hittmair A, Marth C and Widschwendter M (1998) Antiproliferative activity and apoptosis induced by retinoic acid receptor-gamma selectively binding retinoids in neuroblastoma. Anticancer Res 18:1777-1786.
26. O'Connell MJ, Chua R, Hoyos B, Buck J, Chen Y, Derguini F and Hammerling U (1996) Retro-retinoids in regulated cell growth and death. J Exp Med 184:549-555.
27. Oridate N, Higuchi M, Suzuki S, Shroot B, Hong WK and Lotan R (1997) Rapid induction of apoptosis in human C33A cervical carcinoma cells by the synthetic retinoid 6-[3-(1-adamantyl)hydroxyphenyl]-2-naphtalene carboxylic acid (CD437). Int J Cancer 70:484-487.
28. Piedrafita FJ and Pfahl M (1997) Retinoid-induced apoptosis and Sp-1 cleavage occur independently of transcription and require caspase activation. Mol Cell Biol 17:6348-6358.
29. Prosperi E (1997) Multiple roles of the proliferating cell nuclear antigen: DNA replication, repair and cell cycle control. Prog Cell Cycle Res 3:193-210.
30. Ross J (1996) Control of messenger RNA stability in higher eukaryotes. Trends Genet 12:171-175.
31. Schadendorf D, Kern MA, Artuc M, Pahl HL, Rosenbach T, Fichtner I, Nurnberg W, Stuting S, Stebut E, Worm M, Makki A, Jurgovsky K, Kolde G and Henz BM (1996) Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro and causes growth inhibition in xenografts in vivo. J Cell Biol 135:1889-1898.
32. Selvakumaran M, Lin HK, Sjin RT, Reed JC, Liebermann DA and Hoffman B (1994) The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor β1-induced apoptosis of myeloid leu-kemia cells. Mol Cell Biol 14:2352-2360.
33. Shao ZM, Dawson MI, Li XS, Rishi AK, Sheikh MS, Han QX, Ordonez JV, Shroot B and Fontana JA (1995) p53 independent G0/G1 arrest and apoptosis induced by a novel retinoid in human breast cancer cells. Oncogene 11:493-504.
34. Smith ML, Chen IT, Zhan Q, Bae I, Chen CY, Gilmer TM, Kastan MB, O'Connor PM and Fornace AJJ (1994) Interaction of the p53-regulated protein gadd45 with proliferating cell nuclear antigen. Science (Wash DC) 266:1376-1380.
35. Sun SY, Shroot B, Hong WK and Lotan R (1997a) Induction of apoptosis in human non-small cell lung carcinoma cells by the novel synthetic retinoid CD437. J Cell Physiol 173:279-284.
36. Sun SY, Yue P, Dawson MI, Shroot B, Michel S, Lamph WW, Heyman RA, Teng M, Chandraratna RA, Shudo K, Hong WK and Lotan R (1997b) Differential effects of synthetic nuclear retinoid receptor-selective retinoids on the growth of human non-small cell lung carcinoma cells. Cancer Res 57:4931-4939.
37. WAF1/CIP1. Oncogene 12:2579-2594.
38. Zhang LX and Jetten AM (1997) Retinoids and apoptosis, in Advances in Organ Biology, Vol. 3, pp. 161-196, JAI Press, London.
39. Zhan Q, Lord KA, Alamo I, Hollander MC, Carrier F, Ron D, Kohn KW, Hoffman B, Liebermann DA and Fornace AJ (1994) The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Mol Cell Biol 14:2361-2371.
40. Zou CP, Kurie JM, Lotan D, Zou CC, Hong WK and Lotan R (19981 Higher potency of W-(4-hydroxyphenyl)retinamide than all-trans-retinoic acid in induction of apoptosis in non-small cell lung cancer cell lines. Clin Cancer Res 4:1345-1355.