Deletion of serum lectin-reactive α-fetoprotein by acyclic retinoid: A potent biomarker in the chemoprevention of second primary hepatoma

Clinical Cancer Research

Volumn 3, Issue 5, 1997, Pages 727-731

  Moriwaki, Hisataka ^a   Yasuda, Ichiro ^a   Shiratori, Yoshimune ^a   Uematsu, Takahiro ^a   Okuno, Masataka ^a   Muto, Yasutoshi ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; LECTIN; PLACEBO; RETINOID; TUMOR MARKER;

ADULT; AGED; ANTIBODY SPECIFICITY; ARTICLE; CANCER PREVENTION; CLINICAL ARTICLE; CLINICAL PRACTICE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ELECTROPHORESIS; FEMALE; FOLLOW UP; HUMAN; LIVER CELL CARCINOMA; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT;

ALPHA-FETOPROTEINS; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; LECTINS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASMS, SECOND PRIMARY; PLACEBOS; TIME FACTORS; TRETINOIN;

EID: 0030917861     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Sporn, M. B. Carcinogenesis and cancer: different perspectives on the same disease. Cancer Res., 51: 6215-6218, 1991.
2. Moon, R. C., Mehta, R. G., and Rao, K. V. N. Retinoids and cancer in experimental animals. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (eds.), The Retinoids: Biology, Chemistry, and Medicine, Ed. 2, pp. 573-595. New York: Raven Press, 1994.
3. Boone, C. W., Kelloff, G. J., and Malone, W. E. Identification of candidate cancer chemopreventive agents and their evaluation in animal models and human clinical trials. Cancer Res., 50: 2-9, 1990.
4. Hong, W. K., and Itri, L. M. Retinoids and human cancer. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (eds.), The Retinoids: Biology, Chemistry, and Medicine, Ed. 2, pp. 597-630. New York: Raven Press, 1994.
5. Hong, W. K., Lippman, S. M., Hittelman, W. N., and Lotan, R. Retinoid chemoprevention of aerodigestive cancer: from basic research to the clinic. Clin. Cancer Res., 1: 677-686, 1995.
6. Slaughter, P. D., Southwick, H. W., and Smejkel, W. "Field cancerization" in oral stratified epithelium: clinical implications of multicentric cancer. Cancer (Phila.), 6: 963-968, 1953.
7. Hong, W. K., Lippman, S. M., Itri, L. M., Karp, D. D., Lee, J. S., Byers, R. M., Schantz, S. P., Kramer, A. M., Lotan, R., Peters, L. J., Dimery, I. W., Brown, B. W., and Goepfert, H. Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. N. Engl. J. Med., 323: 795-801, 1990.
8. Meyskens, F. L., Surwit, E., Moon, T. E., Davis, J., and Alberts, D. S. A placebo-controlled randomized phase III trial of locally applied β-trans retinoic acid (vitamin A acid, RA) in cervical intraepithelial neoplasia (CIN): favorite effect on CIN II (moderate dysplasia). Proc. Am. Soc. Clin. Oncol., 12: 167, 1993.
9. Muto, Y., Moriwaki, H., Ninomiya, M., Adachi, S., Saito, A., Takasaki, K. T., Tanaka, T., Tsurumi, K., Okuno, M., Tomita, E., Nakamura, T., and Kojima, T. Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. N. Engl. J. Med., 334: 1561-1567, 1996.
10. Aoyagi, Y., Suzuki, Y., Isemura, M., Nomoto, M., Sekiya, C., Igarashi, K., and Ichida, F. The fucosylation index of α-fetoprotein and its usefulness in the early diagnosis of hepatocellular carcinoma. Cancer (Phila.), 61: 769-774, 1988.
11. Taketa, K., Sekiya, C., Namiki, M., Akamatsu, K., Ohta, Y., Endo, Y., and Kosaka, K. Lectin-reactive profiles of α-fetoprotein characterizing hepatocellular carcinoma and related conditions. Gastroenterology, 99: 508-518, 1990.
12. Sato, Y., Nakata, K., Kato, Y., Shima, M., Ishii, N., Koji, T., Taketa, K., and Nagataki, S. Early recognition of hepatocellular carcinoma based on altered profiles of α-fetoprotein. N. Engl. J. Med., 328: 1802-1806, 1993.
13. Taketa, K., Endo, Y., Sekiya, C., Tanikawa, K., Koji, T., Taga, H., Satomura, S., Matsuura, S., Kawai, T., and Hirai, H. A collaborative study for the evaluation of lectin-reactive α-fetoproteins in early detection of hepatocellular carcinoma. Cancer Res., 53: 5419-5423, 1993.
14. Shiraki, K., Takase, K., Tameda, Y., Hamada, M., Kosaka, Y., and Nakano, T. A clinical study of lectin-reactive α-fetoprotein as an early indicator of hepatocellular carcinoma in the follow-up of cirrhotic patients. Hepatology, 22: 802-807, 1995.
15. Yamashita, F., Tanaka, M., Satomura, S., and Tanikawa, K. Prognostic significance of lens culinaris agglutinin A-reactive α-fetoprotein in small hepatocellular carcinomas. Gastroenterology, 111: 996-1001, 1996.
16. Fukutomi, Y., Omori, M., Muto, Y., Ninomiya, M., Okuno, M., and Moriwaki, H. Inhibitory effects of acyclic retinoid (polyprenoic acid) and its hydroxy derivative on cell growth and secretion of α-fetoprotein in human hepatoma-derived cell line (PLC/PRF/5). Jpn. J. Cancer Res., 81: 1281-1285, 1990.
17. Yamada, Y., Shidoji, Y., Fukutomi, Y., Ishikawa, T., Kaneko, T., Nakagama, H., Imawari, M., Moriwaki, H., and Muto, Y. Positive and negative regulations of albumin gene expression by retinoids in human hepatoma cell lines. Mol. Carcinog., 10: 151-158, 1994.
18. Nakamura, N., Shidoji, Y., Yamada, Y., Hatakeyama, H., Moriwaki, H., and Muto, Y. Induction of apoptosis by acyclic retinoid in the human hepatoma-derived cell line. HuH-7. Biochem. Biophys. Res. Commun., 207: 382-388, 1995.
19. Okuno, M., Muto, Y., Kato, M., Ninomiya, M., Moriwaki, H., Noma, A., Tagaya, O., Nozaki, Y., and Suzuki, Y. Inhibitory effect of acyclic retinoid (polyprenoic acid) on the secretion of α-fetoprotein in CCl4-treated rats. J. Nutr. Sci. Vitaminol., 36: 437-446, 1990.
20. Nakamura, N., Shidoji, Y., Moriwaki, H., and Muto, Y. Apoptosis in human hepatoma cell line by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-α. Biochem. Biophys. Res. Commun., 219: 100-104, 1996.
21. Breborowicz, J., Mackiewicz, A., and Breborowicz, D. Microheterogeneity of α-fetoprotein in patient serum as demonstrated by lectin affino-electrophoresis. Scand. J. Immunol., 14: 15-20, 1981.
22. Taketa, K., Ichikawa, E., Taga, H., and Hirai, H. Antibody-affinity blotting, a sensitive technique for the detection of α-fetoprotein separated by lectin affinity electrophoresis in agarose gels. Electrophoresis, 6: 492-497, 1985.
23. Shimizu, K., Taniichi, E., Satomura, S., Matsuura, S., Taga, H., and Taketa, K. Establishment of assay kits for determination of microheterogeneities of α-fetoprotein using lectin affinity electrophoresis. Clin. Chim. Acta., 214: 3-12, 1993.
24. Robins, J. The control of confounding by intermediate variables. Stat. Med. 8: 679-701, 1989.
25. Kaplan, E. L., and Meier, P. Nonparametric estimation for incomplete observations. J. Am. Stat. Assoc., 53: 457-481, 1958.