Tissue transglutaminase-dependent posttranslational modification of the retinoblastoma gene product in promonocytic cells undergoing apoptosis

Molecular and Cellular Biology

Volumn 17, Issue 10, 1997, Pages 6040-6048

  Oliverio, Serafina ^a   Amendola, Alessandra ^a   Di Sano, Federica ^a   Farrace, Maria Grazia ^a   Fesus, Laszlo ^b   Nemes, Zoltan ^b   Piredda, Lucia ^a   Spinedi, Angelo ^a   Piacentini, Mauro ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CALPHOSTIN C; CERAMIDE; DANSYLCADAVERINE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN P53; RETINOBLASTOMA PROTEIN; RETINOIC ACID; TRANSCRIPTION FACTOR E2F;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME SUBSTRATE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MOLECULAR WEIGHT; MONOCYTE; PRIORITY JOURNAL; PROTEIN PROCESSING;

EID: 0030863635     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.10.6040     Document Type: Article

References (46)

1. Almasan, A., Y. Yin, R. E. K. Lee, A. Bradley, W. Li, J. R. Bertino, and G. M. Wahl. 1995. Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. Proc. Natl. Acad. Sci. USA 92:5436-5440.
2. + T lymphocytes and accessory cells in lymphoid tissues. Proc. Natl. Acad. Sci. USA 93:11057-11062.
3. Arends, M. J., and A. H. Wyllie. 1991. Apoptosis. Mechanism and role in pathology. Int. Rev. Exp. Pathol. 32:223-254.
4. Ballesteras, E., C. Abad, and L. Franco. 1996. Core histones are glutaminyl substrates for tissue transglutaminase. J. Biol. Chem. 271:18817-18824.
5. Bing, A., and Q. P. Dou. 1996. Cleavage of retinoblastoma protein during apoptosis: an interleukin lb-converting enzyme-like protease as candidate. Cancer Res. 56:438-442.
6. Bruns, R. F., F. D. Miller, R. L. Merruman, J. J. Howbert, W. H. Heath, E. Kobayashi, I. Takahashi, T. Tamaoki, and H. Nakano. 1991. Inhibition of protein kinase C by calphostin C is light-dependent. Biochem. Biophys. Res. Commun. 176:288-293.
7. DeCaprio, J. A., J. W. Ludlow, L. Dennis, Y. Furukawa, J. Griffin, S. Piwnica-Worms, H. Huang, and D. M. Livingstone. 1989. The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell 58:1085-1095.
8. Ellis, R. E., J. Yuan, and H. R. Horvitz. 1991. Mechanism and functions of cell death. Annu. Rev. Cell Biol. 7:663-698.
9. Fesus, L., and G. Arato. 1986. Quantitation of tissue transglutaminase by a sandwich ELISA system. J. Immunol. Methods 94:131-138.
10. Fesus, L., V. Thomazy, and A. Falus. 1987. Induction and activation of tissue transglutaminase during programmed cell death. FEBS Lett. 224:104-108.
11. Fesus, L., V. Thomazy, F. Autuori, M. P. Cerù, E. Tarcsa, and M. Piacentini. 1989. Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action. FEBS Lett. 245:150-154.
12. Fesus, L., P. J. A. Davies, and M. Piacentini. 1991. Apoptosis: molecular mechanisms in programmed cell death. Eur. J. Cell Biol. 56:170-177.
13. Folk, J. E. 1980. Transglutaminases. Annu. Rev. Biochem. 49:517-531.
14. Gentile, V., V. Thomazy, M. Piacentini, L. Fesus, and P. J. A. Davies. 1992. Expression of tissue transglutaminase in BALB-C 3T3 fibroblasts: effects on cellular morphology and adhesion. J. Cell Biol. 119:463-474.
15. Greenberg, C. S., P. J. Birckbichler, and R. H. Rice. 1992. Transglutaminases: multifunctional cross-linking enzymes that stabilize tissues. FASEB J. 5:3071-3077.
16. Haas-Kogan, D. A., S. C. Kogan, D. Levi, P. A. Dazin T'Ang, Y.-K. T. Fung, and M. A. Israel. 1995. Inhibition of apoptosis by the retinoblastoma gene product. EMBO J. 14:461-472.
17. Hale, A. J., C. A. Smith, L. C. Sutherland, V. E. A. Stoneman, V. L. Longthorne, A. C. Culhane, and G. T. Williams. 1996. Apoptosis: molecular regulation of cell death. Eur. J. Biochem. 236:1-26.
18. Hateboer, G., R. M. Kerkhoven, A. Shvarts, R. Bernards, and R. L. Beijersbergen. 1996. Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins. Genes Dev. 10:2960-2970.
19. Haupt, Y., S. Rowan, and M. Oren. 1995. p53-mediated apoptosis in HeLa cells can be overcome by excess pRB. Oncogene 10:1563-1571.
20. Hofmann, F., F. Martelli, D. M. Livingston, and Z. Wang. 1996. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev. 10:2949-2959.
21. Jacobson, M. D., J. F. Burne, and M. C. Raff. 1994. Programmed cell death and Bcl-2 protection in the absence of a nucleus. EMBO J. 13:1899-1910.
22. Janicke, R. U., P. A. Walker, X. Y. Lin, and A. G. Porter. 1996. Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis. EMBO J. 15:6969-6978.
23. Jarvis, W. D., A. J. Turner, L. F. Povirk, R. S. Traylor, and S. Grant. 1994. Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res. 54:1707-1714.
24. Jones, T. L., and D. Lafrenz. 1992. Quantitative determination of the induction of apoptosis in a murine B cell line using flow cytometric bivariate cell cycle analysis. Cell. Immunol. 142:348-360.
25. Knight, C. R. L., D. Hand, M. Piacentini, and M. Griffin. 1993. Characterization of the transglutaminase-mediated large molecular weight polymer from rat liver; its relationship to apoptosis. Eur. J. Cell Biol. 60:210-217.
26. Koeffler, H. P., C. Miller, M. A. Nicolson, J. Ranyard, and R. A. Bosselman. 1986. Increased expression of p53 protein in human leukemia cells. Proc. Natl. Acad. Sci. USA 83:4035-4039.
27. Kumar, S., and M. F. Lavin. 1996. The ICE family of cysteine proteases as effectors of cell death. Cell Death Differ. 3:255-268.
28. Leszczynski, D., Y. Zhao, M. Luokkamaki, and M. L. Foegh. 1994. Apoptosis of vascular smooth muscle cells. Protein kinase C and oncoprotein Bcl-2 are involved in the regulation of apoptosis in non-transformed rat vascular smooth muscle cells. Am. J. Pathol. 145:1265-1270.
29. Martel, C., E. Batschè, F. Harper, and C. Cremisi. 1996. Inactivation of retinoblastoma gene product RB or an RB-related protein by SV40 T antigen in MDCK epithelial cells results in massive apoptosis. Cell Death Differ. 3:285-298.
30. Melino, G., M. Annicchiarico-Petruzzelli, L. Piredda, E. Candi, V. Gentile, P. J. A. Davies, and M. Piacentini. 1994. "Tissue" transglutaminase and apoptosis: sense and antisense transfection studies in human neuroblastoma cells. Mol. Cell. Biol. 14:6584-6596.
31. Messmer, U. D., E. G. Lapetina, and B. Brüne. 1995. Nitric oxide-induced apoptosis in RAW 264.7 macrophages is antagonized by protein kinase C-and protein kinase A-activating compounds. Mol. Pharmacol. 47:757-765.
32. Morgenbesser, S. D., B. O. Williams, T. K. Jacks, and R. A. DePinho. 1994. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371:72-74.
33. Müller, R. 1995. Transcriptional regulation during the mammalian cell cycle. Trends Genet. 11:173-178.
34. Nakaoka, H., D. M. Perez, K. J. Baek, T. Das, A. Husain, K. Misono, M. Im, and R. M. Graham. 1994. Gh: a GTP-binding protein with transglutaminase activity and receptor signaling function. Science 264:1593-1596.
35. Nemes, Z., R. Adany, M. Balazs, P. Boross, and L. Fesus. Identification of cytoplasmic actin as an abundant glutaminyl substrate for tissue transglutaminase in HL60 and U937 cells undergoing apoptosis. J. Biol. Chem., in press.
36. Piacentini, M., C. Sartori, S. Beninati, A. M. Bargagli, and M. P. Argento-Cerù. 1986. Ornithine decarboxylase, transglutaminase, diamine oxidase and total diamines and polyamines in maternal liver and kidney throughout rat pregnancy. Biochem. J. 234:435-440.
37. Piacentini, M., N. Martinet, S. Beninati, and J. E. Folk. 1988. Free and protein-conjugated polyamines in mouse epidermal cells. J. Biol. Chem. 263:3790-3794.
38. Piacentini, M., F. Autuori, L. Dini, M. G. Farrace, L. Ghibelli, L. Piredda, and L. Fesus. 1991. "Tissue" transglutaminase is specifically expressed in neonatal rat liver cells undergoing apoptosis upon epidermal growth factor-stimulation. Cell Tissue Res. 263:227-235.
39. Piacentini, M., P. J. A. Davies, and L. Fesus. 1994. Transglutaminase in cells undergoing apoptosis, p. 143-163. In L. D. Tomei and F. O. Cope (ed.), Apoptosis: the molecular basis of apoptosis in disease. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
40. Piacentini, M., L. Piredda, D. Starace, M. Annichiarico-Petruzzelli, M. Mattei, S. Oliverio, M. G. Farrace, and G. Melino. 1996. Differential growth of N-and S-type human neuroblastoma cells xenografted into SCID mice. Correlation with apoptosis. J. Pathol. 180:31-38.
41. Piredda, L., A. Amendola, V. Colizzi, P. J. A. Davies, M. G. Farrace, M. Fraziano, V. Gentile, I. Uray, M. Piacentini, and L. Fesus. 1997. Lack of "tissue" transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLlpr/lpr mice. Cell Death Differ. 4:463-472.
42. Slack, R. S., I. S. Skerjanc, B. Lach, J. Craig, K. Jardine, and M. W. McBurney. 1995. Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins. J. Cell Biol. 129:779-788.
43. Weinberg, R. A. 1995. The retinoblastoma product and cell cycle control. Cell 81:323-330.
44. White, E. 1994. p53, guardian of Rb. Nature 371:21-22.
45. Wu, X., and A. J. Levine. 1994. p53 and E2F-1 cooperate to mediate apoptosis Proc. Natl. Acad. Sci. USA 91:3602-3606.
46. Xu, H.-J., K. Xu, Y. Zhou, J. Li, W. F. Benedict, and S.-X. Hu. 1994. Enhanced tumor cell growth suppression by an N-terminal truncated retinoblastoma protein. Proc. Natl. Acad. Sci. USA 91:9837-9841.