-
1
-
-
0032958632
-
Embryonic retinoic acid synthesis is essential for early mouse post-implantation development
-
Niederreither, K., Subbarayan, V., Dolle, P. & Chambon, P. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nature Genet. 21, 444-448 (1999). Targeted gene disruption shows that production of retinoic acid by the retinaldehyde dehydrogenase-2 (Raldh2) enzyme is required for mouse embryo survival and early morphogenesis.
-
(1999)
Nature Genet.
, vol.21
, pp. 444-448
-
-
Niederreither, K.1
Subbarayan, V.2
Dolle, P.3
Chambon, P.4
-
2
-
-
0034672081
-
Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain
-
de Urquiza, A. M. et al. Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science 290, 2140-2144 (2000). Identification of brain-derived docosahexaenoic acid as an RXR ligand.
-
(2000)
Science
, vol.290
, pp. 2140-2144
-
-
De Urquiza, A.M.1
-
3
-
-
0032488783
-
Impaired locomotion and dopamine signaling in retinoid receptor mutant mice
-
Krezel, W. et al. Impaired locomotion and dopamine signaling in retinoid receptor mutant mice. Science 279, 863-867 (1998).
-
(1998)
Science
, vol.279
, pp. 863-867
-
-
Krezel, W.1
-
4
-
-
0029671334
-
Abnormal spermatogenesis in RXRβ mutant mice
-
Kastner, P. et al. Abnormal spermatogenesis in RXRβ mutant mice. Genes Dev. 10, 80-92 (1996).
-
(1996)
Genes Dev.
, vol.10
, pp. 80-92
-
-
Kastner, P.1
-
5
-
-
0347079831
-
Retinoic acid receptor-β: An endogenous inhibitor of the perinatal formation of pulmonary alveoli
-
Massaro, G.D. et al. Retinoic acid receptor-β: an endogenous inhibitor of the perinatal formation of pulmonary alveoli. Physiol. Genomics 4, 51-57 (2000).
-
(2000)
Physiol. Genomics
, vol.4
, pp. 51-57
-
-
Massaro, G.D.1
-
6
-
-
0034035667
-
Hepatocyte-specific mutation establishes retinoid X receptor-α as a heterodimeric integrator of multiple physiological processes in the liver
-
Wan, Y. J. et al. Hepatocyte-specific mutation establishes retinoid X receptor-α as a heterodimeric integrator of multiple physiological processes in the liver. Mol. Cell Biol. 20, 4436-4444 (2000).
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 4436-4444
-
-
Wan, Y.J.1
-
7
-
-
0035836755
-
Selective ablation of retinoid X receptor-α in hepatocytes impairs their lifespan and regenerative capacity
-
Imai, T., Jiang, M., Kastner, P., Chambon, P. & Metzger, D. Selective ablation of retinoid X receptor-α in hepatocytes impairs their lifespan and regenerative capacity. Proc. Natl Acad. Sci. USA 98, 4581-4586 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 4581-4586
-
-
Imai, T.1
Jiang, M.2
Kastner, P.3
Chambon, P.4
Metzger, D.5
-
8
-
-
0033120650
-
Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods
-
Dupe, V. et al. Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dev. Biol. 208, 30-43 (1999).
-
(1999)
Dev. Biol.
, vol.208
, pp. 30-43
-
-
Dupe, V.1
-
9
-
-
0034961181
-
Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand trail
-
Altucci, L. et al. Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand trail. Nature Med. 7, 680-686 (2001). Retinoic-acid therapy of acute promyelocytic leukaemia Involves induction of cell differentiation linked to early-induced anti-apoptotic gene programming, which is followed by post-differentiation apoptosis caused by activation of the TRAIL signalling pathway.
-
(2001)
Nature Med.
, vol.7
, pp. 680-686
-
-
Altucci, L.1
-
10
-
-
0031054372
-
Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development
-
Kastner, P. et al. Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development. Development 124, 313-326 (1997).
-
(1997)
Development
, vol.124
, pp. 313-326
-
-
Kastner, P.1
-
11
-
-
0028967616
-
RAR-speciflc agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation
-
Chen, J. Y. et al. RAR-speciflc agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation. EMBO J. 14, 1187-1197 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 1187-1197
-
-
Chen, J.Y.1
-
12
-
-
0030590241
-
Identification of 9-cis-retinoic acid, 9,13-di-cis-retinoic acid, and 14-hydroxy-4,14-retro-retinol in human plasma after liver consumption
-
Amhold, T., Tzimas, G., Wittfoht, W., Plonait, S. & Nau, H. Identification of 9-cis-retinoic acid, 9,13-di-cis-retinoic acid, and 14-hydroxy-4,14-retro-retinol in human plasma after liver consumption. Life Sci. 59, L169-L177 (1996).
-
(1996)
Life Sci.
, vol.59
-
-
Amhold, T.1
Tzimas, G.2
Wittfoht, W.3
Plonait, S.4
Nau, H.5
-
13
-
-
0026357656
-
Intracellular signaling by 14-hydroxy-4,14-retra-retinol
-
Buck, J., Derguini, F., Levi, E., Nakanishi, K. & Hammerling, U. Intracellular signaling by 14-hydroxy-4,14-retra-retinol. Science 254, 1654-1656 (1991).
-
(1991)
Science
, vol.254
, pp. 1654-1656
-
-
Buck, J.1
Derguini, F.2
Levi, E.3
Nakanishi, K.4
Hammerling, U.5
-
14
-
-
0033868825
-
Crystal structure of a heterodimeric complex of RAH and RXR ligand-binding domains
-
Bourguet, W. et al. Crystal structure of a heterodimeric complex of RAH and RXR ligand-binding domains. Mol. Cell 5, 289-298 (2000).
-
(2000)
Mol. Cell
, vol.5
, pp. 289-298
-
-
Bourguet, W.1
-
15
-
-
0034664769
-
Combinatorial roles of the nuclear receptor corepressor in transcription and development
-
Jepsen, K. et al. Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102, 753-763 (2000).
-
(2000)
Cell
, vol.102
, pp. 753-763
-
-
Jepsen, K.1
-
16
-
-
0034306499
-
Nuclear receptor ligand-binding domains: Three-dimensional structures, molecular interactions and pharmacological implications
-
Bourguet, W., Germain, P. & Gronemeyer, H. Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications. Trends Phamacol. Sci. 21, 381-388 (2000).
-
(2000)
Trends Phamacol. Sci.
, vol.21
, pp. 381-388
-
-
Bourguet, W.1
Germain, P.2
Gronemeyer, H.3
-
17
-
-
0034650893
-
The coregulator exchange in transcriptional functions of nuclear receptors
-
Glass, C. K. & Rosenfeld, M. G. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14, 121-141 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 121-141
-
-
Glass, C.K.1
Rosenfeld, M.G.2
-
19
-
-
0035318741
-
The TRAP/SMCC/mediator complex and thyroid hormone receptor function
-
Ito, M. & Reeder, R. G. The TRAP/SMCC/mediator complex and thyroid hormone receptor function. Trends Endocrinol. Metab. 12, 127-134 (2001).
-
(2001)
Trends Endocrinol. Metab.
, vol.12
, pp. 127-134
-
-
Ito, M.1
Reeder, R.G.2
-
20
-
-
0033572682
-
RAR-independent RXR signaling induces t(15;17) leukemia cell maturation
-
Benoit, G. et al. RAR-independent RXR signaling induces t(15;17) leukemia cell maturation. EMBO J. 18, 7011-7018 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 7011-7018
-
-
Benoit, G.1
-
21
-
-
17844406380
-
Autonomous rexinoid death signaling is suppressed by converging signaling pathways in immature leukemia cells
-
Benoit, G. R. et al. Autonomous rexinoid death signaling is suppressed by converging signaling pathways in immature leukemia cells. Mol. Endocrinol. 15, 1154-1169 (2001). Together with reference 20, this is the first demonstration of autonomous rexinoid signalling.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 1154-1169
-
-
Benoit, G.R.1
|