A complete inventory of fungal kinesins in representative filamentous ascomycetes

Fungal Genetics and Biology

Volumn 39, Issue 1, 2003, Pages 1-15

  Schoch, Conrad L ^a   Aist, James R ^a   Yoder, Olen C ^b   Turgeon, B Gillian ^a  

^a Department of Obstetrics Gynecology   (United States)

^b SYNGENTA BIOTECHNOLOGY INC   (United States)

Author keywords

Ascomycetes; Fungi; Kinesin; Motor proteins; Phylogenetics; Phylogenomics; Protein families

Indexed keywords

CENTROMERE PROTEIN E; CHROMOKINESIN; FUNGAL PROTEIN; KINESIN; KINESIN RELATED PROTEIN; MITOCHONDRIAL CENTROMERE ASSOCIATED KINESIN; PROTEIN BIMC; PROTEIN KAR3P; PROTEIN KID; PROTEIN KIP3P; PROTEIN UNC 104; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ASCOMYCETES; BOTRYOTINIA FUCKELIANA; CARBOXY TERMINAL SEQUENCE; COCHLIOBOLUS HETEROSTROPHUS; COMPARATIVE STUDY; DATA ANALYSIS; EUKARYOTE; EXPERIMENT; FUNGAL GENE; GENETIC MANIPULATION; GIBBERELLA MONILIFORMIS; NEUROSPORA CRASSA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; SEQUENCE ANALYSIS; SPECIES COMPARISON; UNINDEXED SEQUENCE; YEAST;

ASCOMYCOTA; BOTRYOTINIA; BOTRYOTINIA FUCKELIANA; COCHLIOBOLUS; COCHLIOBOLUS HETEROSTROPHUS; EUKARYOTA; FUNGI; GIBBERELLA; GIBBERELLA MONILIFORMIS; MONILIFORMIS; NEUROSPORA; NEUROSPORA CRASSA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE;

EID: 0037992582     PISSN: 10871845     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1087-1845(03)00022-7     Document Type: Review

References (120)

1. Aist J.R. Mitosis and motor proteins in the filamentous ascomycete, Nectria haematococca, and some related fungi. Int. Rev. Cytol. 212:2002;239-263.
2. Baldauf S.L., Roger A.J., Wenk-Siefert I., Doolittle W.F. A kingdom-level phylogeny of eukaryotes based on combined protein data. Science. 290:2000;972-977.
3. Behrens R., Nurse P. Roles of fission yeast tea1p in the localization of polarity factors and in organizing the microtubular cytoskeleton. J. Cell Biol. 157:2002;783-793.
4. Beningo K.A., Lillie S.H., Brown S.S. The yeast kinesin-related protein Smy1p exerts its effects on the class V myosin Myo2p via a physical interaction. Mol. Biol. Cell. 11:2000;691-702.
5. Bloom G.S., Wagner M.C., Pfister K.K., Brady S.T. Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide. Biochemistry. 27:1988;3409-3416.
6. Brady S.T. A novel brain ATPase with properties expected for the fast axonal transport motor. Nature. 317:1985;73-75.
7. Brady S.T., Lasek R.J., Allen R.D. Fast axonal transport in extruded axoplasm from squid giant axon. Science. 218:1982;1129-1131.
8. Brazer S.C., Williams H.P., Chappell T.G., Cande W.Z. A fission yeast kinesin affects Golgi membrane recycling. Yeast. 16:2000;149-166.
9. Brendza R.P., Serbus L.R., Duffy J.B., Saxton W.M. A function for kinesin I in the posterior transport of oskar mRNA and Staufen protein. Science. 289:2000;2120-2122.
10. Brown K.D., Wood K.W., Cleveland D.W. The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A. J. Cell Sci. 109:1996;961-969.
11. Browning H., Hayles J., Mata J., Aveline L., Nurse P., McIntosh J.R. Tea2p is a kinesin-like protein required to generate polarized growth in fission yeast. J. Cell Biol. 151:12000;15-28.
12. Case R.B., Rice S., Hart C.L., Ly B., Vale R.D. Role of the kinesin neck linker and catalytic core in microtubule-based motility. Curr. Biol. 10:2000;157-160.
13. Chen M.C., Zhou Y., Detrich III H.W. Zebrafish mitotic kinesin-like protein 1 (Mklp1) functions in embryonic cytokinesis. Physiol. Genomics. 8:2002;51-66.
14. Cole D.G. Kinesin-II, the heterodimeric kinesin. Cell. Mol. Life Sci. 56:1999;217-226.
15. Cole D.G. Kinesin-II, coming and going. J. Cell Biol. 147:1999;463-466.
16. Cole D.G., Chinn S.W., Wedaman K.P., Hall K., Vuong T., Scholey J.M. Novel heterotrimeric kinesin-related protein purified from sea urchin eggs. Nature. 366:1993;268-270.
17. Cottingham F.R., Gheber L., Miller D.L., Hoyt M.A. Novel roles for Saccharomyces cerevisiae mitotic spindle motors. J. Cell Biol. 147:1999;335-350.
18. Cottingham F.R., Hoyt M.A. Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J. Cell Biol. 138:1997;1041-1053.
19. Dayhoff M.O. The origin and evolution of protein superfamilies. Fed. Proc. 35:1976;2132-2138.
20. DeZwaan T.M., Ellingson E., Pellman D., Roof D.M. Kinesin-related KIP3 of Saccharomyces cerevisiae is required for a distinct step in nuclear migration. J. Cell Biol. 138:1997;1023-1040.
21. Dorner C., Ciossek T., Muller S., Moller P.H., Ullrich A., Lammers R. Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum. J. Biol. Chem. 273:1998;20267-20275.
22. Drummond D.R., Hagan I.M. Mutations in the bimC box of Cut7 indicate divergence of regulation within the bimC family of kinesin related proteins. J. Cell Sci. 111:1998;853-865.
23. Echeverri C.J., Paschal B.M., Vaughan K.T., Vallee R.B. Molecular characterization of the 50-kDa subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J. Cell Biol. 132:1996;617-633.
24. Eisen J.A. Phylogenomics: improving functional predictions for uncharacterized genes by evolutionary analysis. Genome Res. 8:1998;163-167.
25. Eisen J., Wu M. Phylogenetic analysis and gene functional predictions: phylogenomics in action. Theor. Popul. Biol. 61:2002;481.
26. Endow S.A., Waligora K.W. Determinants of kinesin motor polarity. Science. 281:1998;1200-1202.
27. Enos A., Morris N.R. Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in Aspergillus nidulans. Cell. 60:1990;1019-1027.
28. Eriksson, E.O., 2002. Outline of mycota. Myconet, www.umu.se/myconet/Myconet.html.
29. Fischer R. Nuclear movement in filamentous fungi. FEMS Microbiol. Rev. 23:1999;39-68.
30. Garcia M.A., Koonrugsa N., Toda T. Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A. Curr. Biol. 12:2002;610-621.
31. Gheber L., Kuo S.C., Hoyt M.A. Motile properties of the kinesin-related Cin8p spindle motor extracted from Saccharomyces cerevisiae cells. J. Biol. Chem. 274:1999;9564-9572.
32. Goldstein L.S., Philp A.V. The road less traveled: emerging principles of kinesin motor utilization. Annu. Rev. Cell. Dev. Biol. 15:1999;141-183.
33. Goodson H.V., Kang S.J., Endow S.A. Molecular phylogeny of the kinesin family of microtubule motor proteins. J. Cell Sci. 107:1994;1875-1884.
34. Grummt M., Pistor S., Lottspeich F., Schliwa M. Cloning and functional expression of a 'fast' fungal kinesin. FEBS Lett. 427:1998;79-84.
35. Grummt M., Woehlke G., Henningsen U., Fuchs S., Schleicher M., Schliwa M. Importance of a flexible hinge near the motor domain in kinesin-driven motility. EMBO J. 17:1998;5536-5542.
36. Hagan I. The fission yeast microtubule cytoskeleton. J. Cell Sci. 111:1998;1603-1612.
37. Hagan I., Yanagida M. Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene. Nature. 347:1990;563-566.
38. Heck M.M. Dr. Dolittle and the making of the mitotic spindle. BioEssays. 21:1999;985-990.
39. Heck M.M., Perreira A., Pesavento Y., Yannoni A.C. The kinesin-like protein KLP61F is essential for mitosis in Drosophila. J. Cell Biol. 123:1993;665-679.
40. Henikoff S., Greene E.A., Pietrokovski S., Bork P., Attwood T.K., Hood L. Gene families: the taxonomy of protein paralogs and chimeras. Science. 278:1997;609-614.
41. Hildebrandt E.R., Hoyt M.A. Mitotic motors in Saccharomyces cerevisiae. Biochem. Biophys. Acta. 1496:2000;99-116.
42. Hirokawa N. Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science. 279:1998;519-526.
43. Hoyt M.A., He L., Loo K.K., Saunders W.S. Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly. J. Cell Biol. 118:1992;109-120.
44. Hoyt M.A., He L., Totis L., Saunders W.S. Loss of function of Saccharomyces cerevisiae kinesin-related CIN8 and KIP1 is suppressed by KAR3 motor domain mutations. Genetics. 135:1993;35-44.
45. Huang J.D., Brady S.T., Richards B.W., Stenolen D., Resau J.H., Copeland N.G., Jenkins N.A. Direct interaction of microtubule- and actin-based transport motors. Nature. 397:1999;267-270.
46. Huelsenbeck J.P., Ronquist F. MRBAYES: Bayesian inference of phylogenetic trees. Bioinformatics. 17:2001;754-755.
47. Huyett A., Kahana J., Silver P., Zeng X., Saunders W. The Kar3p and Kip2p motors function antagonistically at the spindle poles to influence cytoplasmic microtubule numbers. J. Cell Sci. 111:1998;295-301.
48. Iwabe N., Miyata T. Kinesin-related genes from diplomonad, sponge, amphioxus, and cyclostomes: divergence pattern of kinesin family and evolution of giardial membrane-bounded organella. Mol. Biol. Evol. 19:2002;1524-1533.
49. Jacobs C.W., Adams A.E., Szaniszlo P.J., Pringle J.R. Functions of microtubules in the Saccharomyces cerevisiae cell cycle. J. Cell Biol. 107:1988;1409-1426.
50. Kallipolitou A., Deluca D., Majdic U., Lakamper S., Cross R., Meyhofer E., Moroder L., Schliwa M., Woehlke G. Unusual properties of the fungal conventional kinesin neck domain from Neurospora crassa. EMBO J. 20:2001;6226-6235.
51. Kashina A.S., Baskin R.J., Cole D.G., Wedaman K.P., Saxton W.M., Scholey J.M. A bipolar kinesin. Nature. 379:1996;270-272.
52. Kikkawa M., Okada Y., Hirokawa N. A resolution model of the monomeric kinesin motor, KIF1A. Cell. 100:2000;241-252.
53. Kim A.J., Endow S.A. A kinesin family tree. J. Cell Sci. 113:2000;3681-3682.
54. Kirchner J., Woehlke G., Schliwa M. Universal and unique features of kinesin motors: insights from a comparison of fungal and animal conventional kinesins. Biol. Chem. 380:1999;915-921.
55. Klopfenstein D.R., Tomishige M., Stuurman N., Vale R.D. Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor. Cell. 109:2002;347-358.
56. Kobayashi N., Reiser J., Kriz W., Kuriyama R., Mundel P. Nonuniform microtubular polarity established by CHO1/MKLP1 motor protein is necessary for process formation of podocytes. J. Cell Biol. 143:1998;1961-1970.
57. Lawrence C.J., Malmberg R.I., Muzynski M.G., Dawe R.K. Maximum likelihood methods reveal conservation of function among closely related kinesin families. J. Mol. Evol. 54:2002;42-53.
58. Lehmler C., Steinberg G., Snetselaar K.M., Schliwa M., Kahmann R., Bolker M. Identification of a motor protein required for filamentous growth in Ustilago maydis. EMBO J. 16:1997;3464-3473.
59. Letunic I., Goodstadt L., Dickens N.J., Doerks T., Schultz J., Mott R., Ciccarelli F., Copley R.R., Ponting C.P., Bork P. Recent improvements to the SMART domain-based sequence annotation resource. Nucleic Acids Res. 30:2002;242-244.
60. Lillie S.H., Brown S.S. Smy1p, a kinesin-related protein that does not require microtubules. J. Cell Biol. 140:1998;873-883.
61. Maney T., Hunter A.W., Wagenbach M., Wordeman L. Mitotic centromere-associated kinesin is important for anaphase chromosome segregation. J. Cell Biol. 142:1998;787-801.
62. Maney T., Wagenbach M., Wordeman L. Molecular dissection of the microtubule depolymerizing activity of mitotic centromere-associated kinesin. J. Biol. Chem. 276:2001;34753-34758.
63. Manning B.D., Snyder M. Drivers and passengers wanted! The role of kinesin-associated proteins. Tr. Cell Biol. 10:2000;281-289.
64. Marszalek J.R., Goldstein L.S. Understanding the functions of kinesin-II. Biochim. Biophys. Acta. 1496:2000;142-150.
65. Matthies H.J., Baskin R.J., Hawley R.S. Orphan kinesin NOD lacks motile properties but does possess a microtubule-stimulated ATPase activity. Mol. Biol. Cell. 12:2001;4000-4012.
66. Matuliene J., Kuriyama R. Kinesin-like protein CHO1 is required for the formation of midbody matrix and the completion of cytokinesis in mammalian cells. Mol. Biol. Cell. 13:2002;1832-1845.
67. Meluh P.B., Rose M.D. KAR3, a kinesin-related gene required for yeast nuclear fusion. Cell. 6:1990;1029-1041.
68. Middleton K., Carbon J. KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore. Proc. Natl. Acad. Sci. USA. 91:1994;7212-7216.
69. Miki H., Setou M., Kaneshiro K., Hirokawa N. All kinesin superfamily protein, KIF, genes in mouse and human. Proc. Natl. Acad. Sci. USA. 98:2001;7004-7011.
70. Miller R.K., Heller K.K., Frisen L., Wallack D.L., Loayza D., Gammie A.E., Rose M.D. The kinesin-related proteins, Kip2p and Kip3p, function differently in nuclear migration in yeast. Mol. Biol. Cell. 9:1998;2051-2068.
71. Moore J.D., Endow S.A. Kinesin proteins: a phylum of motors for microtubule-based motility. BioEssays. 18:1996;207-219.
72. Musacchio A., Hardwick K.G. The spindle checkpoint: structural insights into dynamic signalling. Nat. Rev. Mol. Cell Biol. 3:2002;731-741.
73. Nangaku M., Sato-Yoshitake R., Okada Y., Noda Y., Takemura R., Yamazaki H., Hirokawa N. KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell. 79:1994;1209-1220.
74. Niccoli T., Nurse P. Different mechanisms of cell polarisation in vegetative and shmooing growth in fission yeast. J. Cell Sci. 115:2002;1651-1662.
75. Notredame C., Higgins D.G., Heringa J. T-Coffee: a novel method for fast and accurate multiple sequence alignment. J. Mol. Biol. 302:2000;205-217.
76. O'Connell M.J., Morris N.R. Suppression of the bimC4 mitotic spindle defect by deletion of klpA, a gene encoding a KAR3-related kinesin-like protein in Aspergillus nidulans. J. Cell Biol. 120:1993;153-162.
77. Okada Y., Hirokawa N. A processive single-headed motor: kinesin superfamily protein KIF1A. Science. 283:1999;1152-1157.
78. Page B.D., Satterwhite L.L., Rose M.D., Snyder M. Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein. J. Cell Biol. 124:1994;507-519.
79. Pereira A.J., Dalby B., Stewart R.J., Doxsey S.J., Goldstein L.S. Mitochondrial association of a plus end-directed microtubule motor expressed during mitosis in Drosophila. J. Cell Biol. 136:1997;1081-1090.
80. Peretti D., Peris L., Rosso S., Quiroga S., Caceres A. Evidence for the involvement of KIF4 in the anterograde transport of L1-containing vesicles. J. Cell Biol. 149:2000;141-152.
81. Reddy A.S., Day I.S. Kinesins in the Arabidopsis genome: a comparative analysis among eukaryotes. BMC Genomics. 2:2001;1-13.
82. Requena N., Alberti-Segui C., Winzenburg E., Horn C., Schliwa M., Philippsen P., Liese R., Fischer R. Genetic evidence for a microtubule-destabilizing effect of conventional kinesin and analysis of its consequences for the control of nuclear distribution in Aspergillus nidulans. Mol. Microbiol. 42:2001;121-132.
83. Roof D.M., Meluh P.B., Rose M.D. Kinesin-related proteins required for assembly of the mitotic spindle. J. Cell Biol. 118:1992;95-108.
84. Sakowicz R., Farlow S., Goldstein L.S. Cloning and expression of kinesins from the thermophilic fungus Thermomyces lanuginosus. Protein Sci. 8:1999;2705-2710.
85. Saunders W., Lengyel V., Hoyt M.A. Mitotic spindle function in Saccharomyces cerevisiae requires a balance between different types of kinesin-related motors. Mol. Biol. Cell. 8:1997;1025-1033.
86. Saunders W.S., Hoyt M.A. Kinesin-related proteins required for structural integrity of the mitotic spindle. Cell. 70:1992;451-458.
87. Schaar B.T., Chan G.K., Maddox P., Salmon E.D., Yen T.J. CENP-E function at kinetochores is essential for chromosome alignment. J. Cell Biol. 139:1997;1373-1382.
88. Schultz J., Milpetz F., Bork P., Ponting C.P. SMART, a simple modular architecture research tool: identification of signaling domains. Proc. Natl. Acad. Sci. USA. 95:1998;5857-5864.
89. Seiler S., Kirchner J., Horn C., Kallipolitou A., Woehlke G., Schliwa M. Cargo binding and regulatory sites in the tail of fungal conventional kinesin. Nat. Cell Biol. 2:2000;333-338.
90. Seiler S., Nargang F.E., Steinberg G., Schliwa M. Kinesin is essential for cell morphogenesis and polarized secretion in Neurospora crassa. EMBO J. 16:1997;3025-3034.
91. Seiler S., Plamann M., Schliwa M. Kinesin and dynein mutants provide novel insights into the roles of vesicle traffic during cell morphogenesis in Neurospora. Curr. Biol. 9:1999;779-785.
92. Sharp D.J., Rogers G.C., Scholey J.M. Microtubule motors in mitosis. Nature. 407:2000;41-47.
93. Siddiqui S.S. Metazoan motor models: kinesin superfamily in C. elegans. Traffic. 3:2002;20-28.
94. Simon V.R., Pon L.A. Actin-based organelle movement. Experientia. 52:1996;1117-1122.
95. Sipiczki M. Where does fission yeast sit on the tree of life? Genome Biol. 1:2000;1-4.
96. Song Y.H., Marx A., Muller J., Woehlke G., Schliwa M., Krebs A., Hoenger A., Mandelkow E. Structure of a fast kinesin: implications for ATPase mechanism and interactions with microtubules. EMBO J. 20:2001;6213-6225.
97. Steinberg G. A kinesin-like mechanoenzyme from the zygomycete Syncephalastrum racemosum shares biochemical similarities with conventional kinesin from Neurospora crassa. Eur. J. Cell Biol. 73:1997;124-131.
98. Steinberg G. Organelle transport and molecular motors in fungi. Fungal. Genet. Biol. 24:1998;161-177.
99. Steinberg G. The cellular roles of molecular motors in fungi. Tr. Microbiol. 8:2000;162-168.
100. Steinberg G., Schliwa M. The Neurospora organelle motor: a distant relative of conventional kinesin with unconventional properties. Mol. Biol. Cell. 6:1995;1605-1618.
101. Steinberg G., Schliwa M. Characterization of the biophysical and motility properties of kinesin from the fungus Neurospora crassa. J. Biol. Chem. 271:1996;7516-7521.
102. Steinberg G., Schliwa M., Lehmler C., Bolker M., Kahmann R., McIntosh J.R. Kinesin from the plant pathogenic fungus Ustilago maydis is involved in vacuole formation and cytoplasmic migration. J. Cell Sci. 111:1998;2235-2246.
103. Stock M.F., Guerrero J., Cobb B., Eggers C.T., Huang T.G., Li X., Hackney D.D. Formation of the compact confomer of kinesin requires a COOH-terminal heavy chain domain and inhibits microtubule-stimulated ATPase activity. J. Biol. Chem. 274:1999;11423-14617.
104. Su S., Yanagida M. Mitosis and cytokinesis in the fission yeast, Schizosaccharomyces Pombe. Pringle J.R., Broach J.R., Jones E.W. The molecular and cellular biology of the yeast Saccharomyces cerevisiae. vol. 3:1997;765-825 Cold Spring Harbor Laboratory Press, Plainview, New York.
105. Suelmann R., Fischer R. Mitochondrial movement and morphology depend on an intact actin cytoskeleton. Cell Motil. Cytoskeleton. 45:2000;42-50.
106. Tokai N., Fujimoto-Nishiyama A., Toyoshima Y., Yonemura S., Tsukita S., Inoue J., Yamamota T. Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle. EMBO J. 15:1996;457-467.
107. Troxell C.L., Sweezy M.A., West R.R., Reed K.D., Carson B.D., Pidoux A.L., Cande W.Z., McIntosh J.R. pkl1(+)and klp2(+): two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis. Mol. Biol. Cell. 12:2001;3476-3488.
108. Vale R.D., Fletterick R.J. The design plan of kinesin motors. Annu. Rev. Cell Dev. Biol. 13:1997;745-777.
109. Vale R.D., Reese T.S., Sheetz M.P. Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell. 42:1985;39-50.
110. Vernos I., Raats J., Hirano T., Heasman J., Karsenti E., Wylie C. Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning. Cell. 81:1995;117-127.
111. Wang S.Z., Adler R. Chromokinesin: a DNA-binding, kinesin-like nuclear protein. J. Cell Biol. 128:1995;761-768.
112. Wedlich-Soldner R., Straube A., Friedrich M.W., Steinberg G. A balance of KIF1A-like kinesin and dynein organizes early endosomes in the fungus Ustilago maydis. EMBO J. 21:2002;2946-2957.
113. West R.R., Malmstrom T., McIntosh J.R. Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis. J. Cell Sci. 115:2002;931-940.
114. West R.R., Malmstrom T., Troxell C.L., McIntosh J.R. Two related kinesins, klp5(+) and klp6(+), foster microtubule disassembly and are required for meiosis in fission yeast. Mol. Biol. Cell. 12:2001;3919-3932.
115. Westerholm-Parvinen A., Vernos I., Serrano L. Kinesin subfamily UNC104 contains a FHA domain: boundaries and physicochemical characterization. FEBS Lett. 486:2000;285-290.
116. Wood K.W., Sakowicz R., Goldstein L.S., Cleveland D.W. CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment. Cell. 91:1997;357-366.
117. Wordeman L., Mitchison T.J. Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis. J. Cell Biol. 128:1995;95-104.
118. Wu Q., Sandrock T.M., Turgeon B.G., Yoder O.C., Wirsel S.G., Aist J.R. A fungal kinesin required for organelle motility, hyphal growth, and morphogenesis. Mol. Biol. Cell. 9:1998;89-101.
119. Yang J.T., Saxton W.M., Stewart R.J., Raff E.C., Goldstein L.S.B. Evidence that the head of kinesin is sufficient for force generation and motility in vitro. Science. 249:1990;42-47.
120. Yen T.J., Compton D.A., Wise D., Zinkowski R.P., Brinkley B.R., Earnshaw W.C., Cleveland D.W. CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. EMBO J. 10:1991;1245-1254.