Kinesin proteins: A phylum of motors for microtubule-based motility

BioEssays

Volumn 18, Issue 3, 1996, Pages 207-219

  Moore, Jonathan D ^a   Endow, Sharyn A ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KINESIN;

ANIMAL; CELL DIVISION; CELL MOTION; CLASSIFICATION; GENETICS; HUMAN; MICROTUBULE; MITOSIS SPINDLE; MOLECULAR GENETICS; PHYLOGENY; PHYSIOLOGY; REVIEW;

ANIMALS; CELL DIVISION; CELL MOVEMENT; HUMANS; KINESIN; MICROTUBULES; MITOTIC SPINDLE APPARATUS; MOLECULAR SEQUENCE DATA; PHYLOGENY;

ANIMALIA;

EID: 0030111466     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.950180308     Document Type: Article

References (78)

1. Brady, S.T. (1985). A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317, 73-75.
2. Vale, R.D., Reese, T.S. and Sheetz, M.P. (1985). Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell 42, 39-50.
3. Enos, A.P. and Morris, N.R. (1990). Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans. Cell 60, 1019-1027.
4. Endow, S.A., Henikoff, S. and Soler-Niedziela, L. (1990). Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin. Nature 345, 81-83.
5. Zhang, P., Knowles, B.A., Goldstein, L.S.B, and Hawley, R.S. (1990). A kinesin-like protein required for distributive chromosome segregation in Drosophila. Cell 62, 1053-1062.
6. Meluh, P.B. and Rose, M.D. (1990). KAR3, a kinesin-related gene required for yeast nuclear fusion. Cell 60, 1029-1041.
7. Yang, J.T., Laymon, R.A. and Goldstein, L.S.B. (1989). A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. Cell 56, 879-889.
8. Stewart, R.J., Thaler, J.P. and Goldstein, L.S.B. (1993). Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd protein. Proc. Natl Acad. Sci. USA 90, 5209-5213.
9. McDonald, H.B. and Goldstein, L.S.B. (1990) Identification and characterization of a gene encoding a kinesin-like protein in Drosophila. Cell 61, 991-1000.
10. Endow, S.A. and Hatsumi, M. (1991). A multimember kinesin gene family in Drosophila. Proc. Natl Acad. Sci. USA 88, 4424-4427.
11. Sawin, K.E., Mitchison, T.J. and Wordeman, L.G. (1992) Evidence for kinesin-related proteins in the mitotic apparatus using peptide antibodies. J. Cell Sci. 101, 303-313.
12. Goodson, H.V., Kang, S.J. and Endow, S.A. (1994). Molecular phylogeny of the kinesin family of microtubule motor proteins. J. Cell Sci. 107, 1875-1884.
13. Bloom, G.S. and Endow, S.A. (1994). Motor Proteins 1: Kinesins. Protein Profile 1, 1059-1116.
14. Pereira, A. and Goldstein, L.S.B. (1994). The kinesin superfamily. In Microtubules (ed. J. S. Hyams and C. W. Lloyd), pp. 269-284. Wiley-Liss: New York.
15. Scholey, J.M., Porter, M.E., Grissom, P.M. and McIntosh, J.R. (1985) Identification of kinesin in sea urchin eggs, and evidence for its localization in the mitotic spindle. Nature 318, 483-486.
16. Hirokawa, N., Pfister, K.K., Yorifuji, H., Wagner, M.C., Brady, S.T. and Bloom, G.S. (1989). Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration. Cell 56, 867-878.
17. de Cuevas, M., Tao, T. and Goldstein, L.S.B. (1992). Evidence that the stalk of Drosophila kinesin heavy chain is an α-helical coiled coil. J. Cell Biol. 116, 957-965.
18. Cyr, J.L., Pfister, K.K., Bloom, G.S., Slaughter, C.A. and Brady, S.T. (1991). Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing. Proc. Natl Acad. Sci. USA 88, 10114-10118.
19. Vale, R.D., Schnapp, B.J., Mitchison, T., Steuer, E., Reese, T.S. and Sheetz, M.P. (1985). Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell 43, 623-632.
20. Saxton, W.M., Porter, M.E., Cohn, S.A., Scholey, J.M., Raff, E.C. and McInosh, J.R. (1988). Drosophila kinesin: characterization of microtubule motility and ATPase. Proc. Natl Acad. Sci. USA, 85, 1109-1113.
21. Porter, M.E. et al. (1987). Characterization of the microtubule movement produced by sea urchin egg kinesin. J. Biol. Chem. 262, 2794-2802.
22. Hirokawa, N., Sato-Yoshitake, R., Kobayashi, N., Pfister, K.K., Bloom, G.S. and Brady, S.T. (1991). Kinesin associates with anterogradely transported membranous organelles In vivo. J. Cell Biol. 114, 295-302.
23. Lippincott-Schwartz, J., Cole, N.B., Marotta, A., Conrad, P.A. and Bloom, G.S. (1995). Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic. J. Cell Biol. 128, 293-306.
24. Kumar, J., Yu, H. and Sheetz, M.P. (1995). Kinecfin, an essential anchor for kinesin-driven motility. Science 267, 1834-1837.
25. Saxton, W.M., Hicks, J., Goldstein, L.S.B, and Raff, E.C. (1991). Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila. but mutants show no defects in mitosis. Cell 64,1093-1102.
26. Hall, D.H., Plenefisch, J. and Hedgecock, E.M. (1991). Ultrastructural abnormalities of kinesin mutant unc-116. J. Cell Biol. 115, 389a.
27. Patel, N., Thierrymieg, D. and Mancillas, J.R. (1993). Cloning by insertional mutagenesis of a cDNA encoding Caenorhabditis elegans kinesin heavy chain. Proc. Natl Acad. Sci. USA 90, 9181-9185.
28. Niclas, J., Navone, F., Hom-Booher, N. and Vale, R.D. (1994). Cloning and localization of a conventional kinesin motor expressed exclusively in neurons. Neuron 12, 1059-1072.
29. Aizawa, H., Sekine, Y., Takemura, R., Zhang, Z., Nangaku, M. and Hirokawa, N. (1992). Kinesin family in murine central nervous system. J. Cell Biol. 119, 1287-1296.
30. Steinberg, G. and Schliwa, M. (1995). The Neurospora organelle motor: a distant relative of kinesin with unconventional properties. Molec. Biol. Cell 6, 1605-1618.
31. Okada, Y., Yamakazi, H., Sekine-Aizawa, Y. and Hirokawa, N. (1995). The neuron specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Cell 81, 769-780.
32. Nangaku, M. et al. (1994). KIF1B, a novel microtubule plus end directed monomeric motor protein for transport of mitochondria. Cell 79, 1209-1220.
33. Hall, D.H. and Hedgecock, E.M. (1991).Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans. Cell 65, 837-847.
34. Otsuka, A.J. et al. (1991).The C. elegans unc-104 gene encodes a putative kinesin heavy chain-like protein. Neuron 6, 113-122.
35. O'Shea, E.K., Klemm, J.D., Kim, P.S. and Alber, T. (1991).X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. Science 254, 539-544.
36. Berliner, E., Young, E.C., Anderson, K., Mahtani, H.K. and Gelles, J. (1995).Failure of a single-headed kinesin to track parallel to microtubule protofilaments. Nature 373, 718-721.
37. Cole, D.G., Chinn, S.W., Wedaman, K.P., Hall, K., Vuong, T. and Scholey, J.M. (1993). Novel heterotrimeric kinesin-related protein purified from sea urchin eggs. Nature 366, 268-270.
38. Rashid, D.J., Wedaman, K.P. and Scholey, J.M. (1995). Heterodimenzation of the two motor subunits of the heterotrimeric kinesin. KRP85/95. J. Mol. Biol. 252, 157-162.
39. Kondo, S. et al. (1994). KIF3A is a new microtubule based anterograde motor in the nerve axon. J. Cell Biol. 125, 1095-1107.
40. Walther, Z., Vashishtha, M. and Hall, J.L. (1994) The Chlamydomonas FLA10 gene encodes a novel protein. J. Cell Biol. 126, 175-188.
41. Pesavento, P.A., Stewart, R.J. and Goldstein, L.S.B. (1994). Characterization of the KLP68D kinesin-like protein in Drosophila: possible roles in axonal transport. J. Cell Biol. 127, 1041-1048.
42. Shakir, M.A., Fukushige, T., Yasuda, H., Miwa, J. and Siddiqui, S.S. (1993) C. elegans osm-3 gene mediating osmotic avoidance behaviour encodes a kinesin-like protein. NeuroReport 4, 891-894.
43. Perkins, L.A., Hedgecock, E.M., Thomson, J.N. and Culotti, J.G. (1986) Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev. Biol. 117, 456-487.
44. Walker, R.A., Salmon, E.D. and Endow, S.A. (1990). The Drosophila claret segregation protein is a minus-end directed motor molecule. Nature 347, 780-782.
45. Chandra, R., Salmon, E.D., Erickson, H.P., Lockhart, A. and Endow, S.A. (1993). Structural and functional domains of the Drosophila ncd microtubule motor protein. J. Biol. Chem. 268, 9005-9013.
46. Hatsumi, M. and Endow, S.A. (1992). The Drosophila ncd microtubule motor protein is spindle-associated in meiotic and mitotic cells. J. Cell Sci. 103, 1013-1020.
47. Endow, S.A., Chandra, R., Komma, D.J., Yamamoto, A.H. and Salmon, E.D. (1994). Mutants of the Drosophila ncd microtubule motor protein cause centrosomal and spindle pole defects in mitosis. J. Cell Sci. 107, 859-867.
48. Endow, S.A., Kang, S.J., Satterwhite, L.L., Rose, M.D., Skeen, V.P. and Salmon, E.D. (1994). Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends. EMBO J. 13, 2708-2713.
49. Kuriyama, R. et al. (1995). Characterization of a minus end-directed kinesin-like motor protein from cultured mammalian cells. J. Cell Biol. 129, 1049-1059.
50. Hoyt, M.A., He, L., Totis, L. and Saunders, W.S. (1993) Loss of function of Saccharomyces cerevisiae kinesin-related CIN8 and KIP1 is suppressed by KAR3 motor domain mutations. Genetics 135, 35-44.
51. O'Connell, M.J., Meluh, P.B., Rose, M.D. and Morris, N.R. (1993) Suppression of the bimC4 mitotic spindle defect by deletion of klpA, a gene encoding a KAR3-related kinesin-like protein in Aspergillus nidulans. J. Cell Biol. 120, 153-162.
52. Middleton, K. and Carbon, J. (1994). Kar3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore. Proc. Natl Acad. Sci. USA 91, 7212-7216.
53. Mitsui, H., Yamaguchi-Shinozaki, K., Shinozaki, K., Nishikawa, K. and Takahashi, H. (1993). Identification of a gene family (kat) encoding kinesin-like proteins in Arabidopsis thaliana and the characterization of secondary structure of KatA. Mol. Gen. Genet. 238, 362-368.
54. Hagan, I. and Yanagida, M. (1992). Kinesin-related cut7 protein associates with mitotic and meiotic spindles in fission yeast. Nature 356, 74-76.
55. Hoyt, M.A., He, L., Loo, K.K. and Saunders, W.S. (1992). Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly. J. Cell Biol. 118, 109-120.
56. Heck, M.M.S., Pereira, A., Pesavento, P., Yannoni, Y., Spradling, A.C. and Goldstein, L.S.B. (1993). The kinesin-like protein KLP61F is essential for mitosis in Drosophila. J. Cell Biol. 123, 665-679.
57. Sawin, K.E., LeGuellec, K., Philippe, M. and Mitchison, T.J. (1992). Mitotic spindle organization by a plus-end-directed microtubule motor. Nature 359, 540-543.
58. Sawin, K.E. and Mitchison, T.J. (1995). Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle. Proc. Natl Acad. Sci. USA 92, 4289-4293.
59. Cole, D.G., Saxton, W.M., Sheehan, K.B. and Scholey, J.M. (1994). A 'slow' homotetrameric kinesin-related motor protein purified from Drosophila embryos. J. Biol. Chem. 269, 22913-22916.
60. Nislow, C., Lombillo, V.A., Kuriyama, R. and McIntosh, J.R. (1992) A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles. Nature 359, 543-547.
61. Sekine, Y. et al. (1994). A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally. J. Cell Biol. 127, 187-201.
62. Vernos, I., Raats, J., Hirano, T., Heasman, J., Karsenti, E. and Wylie, C. (1995). Xklp1, a chromosomal Xenopus kinesin like protein essential for spindle organization and chromosome positioning. Cell 81, 117-127.
63. Wang, S.Z. and Adler, R. (1995). Chromokinesin: a DNA-binding, kinesin-like protein. J. Cell Biol. 128, 861-768.
64. Williams, B.C., Reidy, M.F., Williams, E.V., Gatti, M. and Goldberg, M.L. (1995). The Drosophila kinesin-like protein KLP3A is a midbody component required for central spindle assembly and initiation of cytokinesis. J. Cell Biol. 129, 709-723.
65. Foss, M., Wein, H. and Cande, W.Z. (1993). Identifying kinesins and other proteins in diatom mitotic spindles. Molec. Biol. Cell 4, 243a.
66. Wordeman, L. and Mitchison, T.J. (1995). Identification and partial characterization of mitotic centromere-associated kinesin. a kinesin-related protein that associates with centromeres during mitosis. J. Cell Biol 128, 95-105.
67. Lombillo, V.A., Stewart, R.J. and McIntosh, J.R. (1995) Minus-end-directed motion of kinesin-coated microspheres driven by microtubule depolymerization. Nature 373, 161-164.
68. Noda, Y., Sato-Yoshitake, R., Kondo, S., Nangaku, M. and Hirokawa, N. (1995). KIF2 is a new microtubule based anterograde motor that transports membranous organelles distinct from those carried by kinesin heavy chain of KIF3A/B. J. Cell Biol. 129, 157-167.
69. Afshar, K., Barton, N.R., Hawley, R.S. and Goldstein, L.S.B. (1995). DNA binding and meiotic chromosomal localization of the Drosophila nod kinesin-like protein. Cell 81, 129-138.
70. Lillie, S.H. and Brown, S.S. (1992). Suppression of a myosin defect by a kinesin-related gene. Nature 356, 358-361.
71. Bernstein, M., Beech, P.L., Katz, S.G. and Rosenbaum, J.L. (1994) A new kinesin-like protein, Klp1, localized to a single microtubule in the Chlamydomonas flagellum. J. Cell Biol. 125, 1313-1326.
72. Yen, T.J., Li, G., Schaar, B.T., Szilak, I. and Cleveland, D.W. (1992) CENP-E is a putative kinetochore motor that accumulates just before mitosis. Nature 359, 536-539.
73. Lombilio, V.A., Nislow, C., Yen, T.J., Gelfand, V.I. and McIntosh, J.R. (1995). Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro. J. Cell Biol. 128, 107-115.
74. Thrower, D.A., Jordan, M.A., Schaar, B.T., Yen, T.J. and Wilson, L. (1995). Mitotic HeLa cells contain a CENP-E associated minus end-directed microtubule motor. EMBO J. 14, 918-926.
75. Chandra, R., Endow, S.A. and Salmon, E.D. (1993). An N terminal truncation of the ncd motor protein supports diffusional movement of microtubles in motility assays. J. Cell Sci. 104, 899-906.
76. Wang, S. and Hazelrigg, T. (1994). Implications for bcd mRNA localization from spatial distribution of exu protein in Drosophila oogenesis. Nature 369, 400-403.
77. Swofford, D.L. (1993). PAUP: Phylogenetic Analysis Using Parsimony. 3.1.1 ed. Vol. 3.1.1. Computer program distributed by the Illinois Natural History Survey, Champaign, IL 61820.
78. Felsenstein, J. (1985). Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39, 783-791.