Nonuniform microtubular polarity established by CHO1/MKLP1 motor protein is necessary for process formation of podocytes

Journal of Cell Biology

Volumn 143, Issue 7, 1998, Pages 1961-1970

  Kobayashi, Naoto ^a,d   Reiser, Jochen ^a   Kriz, Wilhelm ^a   Kuriyama, Ryoko ^b   Mundel, Peter ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CHO1 MKLP1; Glomerular podocyte; Microtubular polarity; Microtubule organizing center; Process formation

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; KINESIN; MESSENGER RNA; NOCODAZOLE; PROTEIN; TUBULIN;

ANIMAL CELL; ARTICLE; CELL POLARITY; CENTROSOME; CONTROLLED STUDY; CYTOSKELETON; MICROTUBULE; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL DIFFERENTIATION; CELL POLARITY; CENTROSOME; CRICETINAE; GENE EXPRESSION REGULATION; KIDNEY GLOMERULUS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MOLECULAR MOTOR PROTEINS; RNA, MESSENGER; TUBULIN;

ANIMALIA; ZUNIGA;

EID: 0032576544     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.143.7.1961     Document Type: Article

References (18)

1. Ahmad, F.J., C.J. Jcheverri, R.B. Vallee, and P.W. Baas. 1998. Cytoplasmic dynein and dynactin are required for the transport of microtubules into the axon. J. Cell Biol. 140:391-401.
2. Baas, P.W. 1997. Microtubules and axonal growth. Curr. Opin. Cell Biol. 9:29-36.
3. Baas, P.W., and A. Brown. 1997. Slow axonal transport: the polymer transport model. Trends Cell Biol. 7:380-384.
4. Baas, P.W., and H.C. Joshi. 1992. γ-Tubulin distribution in the neuron: implications for the origins of neuritic microtubules. J. Cell Biol. 119:171-178.
5. Baas, P.W., J.S. Deitch, M.M. Black, and G.A. Banker. 1988. Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrites. Proc. Natl. Acad. Sci. USA. 85:8335-8339.
6. Baas, P.W., M.M. Black, and G.A. Banker. 1989. Changes in microtubule polarity orientation during the development of hippocampal neurons in culture. J Cell Biol. 109:3085-3094.
7. Baas, P.W., T.P. Pienkowski, and K.S. Kosik. 1991. Processes induced by tau expression in Sf9 cells have an axon-Iike microtubule organization. J. Cell Biol. 115:1333-1344.
8. Cells, J.E., J.V. Small, P.M. Larsen, S.J. Fey, J. De Mey, and A. Celis. 1984. Intermediate filaments in monkey kidney TC7 cells; focal centers and interrelationship with other cytoskeletal systems. Proc. Natl. Acad. Sci USA. 81: 1117-1121.
9. Chen, J., Y. Kanai, NJ. Cowan, and N. Hirokawa. 1992. Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons. Nature. 360:674-677.
10. De Brabander, M., G. Geuens, R. Nuydens, R. Willebrords, and J. De Mey. 1981. Taxol induces the assembly of free microtubules in living cells and blocks the organization capacity of the centrosomes and kinetochores. Proc. Natl. Acad. Sci. USA. 78:5608-5612.
11. de Hoop, M.J., and C.G. Dotti. 1993. Membrane traffic in polarized neurons in culture. J. Cell Sci. 17(Suppl.):85-92.
12. Echard, A., F. Jollivet, O. Martinez, J.J. Lacapere, A. Rousselet, I. JanoueixLerosey, and B. Goud. 1998. Interaction of a Golgi-associated kinesin-like protein with Rab6. Science. 279:580-585.
13. Heidemann, S.R. 1991. Microtubule polarity determination based on formation of protofilament hooks. Methods Enzymol. 196:469-477.
14. Heidemann, S.R., M.A. Hamborg, S.J. Thomas, B. Song, S. Lindley, and D. Chu. 1984. Spatial organization of axonal microtubules. J. Cell Biol. 99:1289-1295.
15. Heidemann, S.R., J.M. Landers, and M.A. Mamborg. 1981. Polarity orientation of axonal microtubules. J. Cell Biol. 91:661-665.
16. Hirokawa, N. 1997. The mechanism of fast and slow transport in neurons: identification and characterization of the new kinesin superfamily motors. Curr. Opin. Neurobiol. 7:605-614.
17. Hirokawa, N., S. Terada, T. Funakoshi, and S. Takeda. 1997. Slow axonal transport: the subunit transport model. Trends Cell Biol. 7:384-388.
18. Huber, L.A., M.J. de Hoop, P. Dipree, M. Zerial, K. Simons, and C.G. Dotti. 1993a. Protein transport to the dendritic plasma membrane of cultured neurons is regulated by rab8p. J. Cell Biol. 123:47-55.