Smy1p, a kinesin-related protein that does not require microtubules

Journal of Cell Biology

Volumn 140, Issue 4, 1998, Pages 873-883

  Lillie, S H ^a   Brown, S S ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASM PROTEIN; KINESIN;

ARTICLE; CELL MOTILITY; CELLULAR DISTRIBUTION; MICROTUBULE; MUTATION; NONHUMAN; PRIORITY JOURNAL;

CARRIER PROTEINS; FUNGAL PROTEINS; GENES, LETHAL; KINESIN; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MUTATION; MYOSIN HEAVY CHAINS; MYOSIN TYPE II; MYOSIN TYPE V; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES POMBE PROTEINS;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 0032559545     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.140.4.873     Document Type: Article

References (50)

1. Adams, A.E.M., and J.R. Pringle. 1984. Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae. J. Cell Biol. 98:934-945.
2. Brockerhoff, S.E., R.C. Stevens, and T.N. Davis. 1994. The unconventional myosin, Myo2p, is a calmodulin target at sites of cell growth in Saccharomyces cerevisiae. J. Cell Biol. 124:315-323.
3. Carminati, J.L., and T. Stearns. 1997. Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex. J. Cell Biol. 138:629-641.
4. Clanton, D.J., Y. Lu, D.G. Blair, and T.Y. Shih. 1987. Structural significance of the GTP-binding domain of ras p21 studied by site-directed mutagenesis. Mol. Cell. Biol. 7:3092-3097.
5. Cottingham, F.R., and M.A. Hoyt. 1997. Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J. Cell Biol. 138:1041-1053.
6. DeZwaan, T.M., E. Ellingson, D. Pellman, and D.M. Roof. 1997. Kinesin-related KIP3 of Saccharomyces cerevisiae is required for a distinct step in nuclear migration. J. Cell Biol. 138:1023-1040.
7. Fath, K.R., G.M. Trimbur, and D.R. Burgess. 1994. Molecular motors are differentially distributed on Golgi membranes from polarized epithelial cells. J. Cell Biol. 126:661-675.
8. Goldstein, L.S.B. 1993. With apologies to Scheherazade: tails of 1001 kinesin motors. Annu. Rev. Genet. 27:319-351.
9. Govindan, B., R. Bowser, and P. Novick. 1995. The role of Myo2, a yeast class V myosin, in vesicular transport. J. Cell Biol. 128:1055-1068.
10. Haarer, B.K., A. Petzold, S.H. Lillie, and S.S. Brown. 1994. Identification of MYO4, a second class V myosin gene in yeast. J. Cell Sci. 107:1055-1064.
11. Hackney, D.D. 1994. Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis. Proc. Natl. Acad. Sci. USA. 91: 6865-6869.
12. Hill, J.E., A.M. Meyers, T.J. Koerner, and A. Tzagoloff. 1986. Yeast/E. coli shuttle vectors with multiple unique restriction sites. Yeast. 2:163-167.
13. Huffaker, T.C., J.H. Thomas, and D. Botstein. 1988. Diverse effects of β-tubulin mutations on microtubule formation and function. J. Cell Biol. 106:1997-2010.
14. Jacobs, C.W., A.E.M. Adams, P.J. Szaniszlo, and J.R. Pringle. 1988. Functions of microtubules in the Saccharomyces cerevisiae cell cycle. J. Cell Biol. 107: 1409-1426.
15. Johnston, G.C., and R.A. Singer. 1980. Ribosomal precursor RNA metabolism and cell division in the yeast Saccharomyces cerevisiae. Molec. Gen. Genet. 178:357-360.
16. Johnston, G.C., J.A. Prendergast, and R.A. Singer. 1991. The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles. J. Cell Biol. 113:539-551.
17. Kilmartin, J.V., and A.E.M. Adams. 1984. Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J. Cell Biol. 98: 922-933.
18. Kull, F.J., E.P. Sablin, R. Lau, R.J. Fletterick, and R.D. Vale. 1996. Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature. 380:550-555.
19. Langford, G.M. 1995. Actin-and microtubule-dependent organelle motors: interrelationships between the two motility systems. Cnrr. Opin. Cell Biol. 7:82-88.
20. Lillie, S.H., and J.R. Pringle. 1980. Reserve carbohydrate metabolism in Saccharomyces cerevisiae: responses to nutrient limitation. J. Bacteriol. 143: 1384-1394.
21. Lillie, S.H., and S.S. Brown. 1992. Suppression of a myosin defect by a kinesin-related gene. Nature. 356:358-361.
22. Lillie, S.H., and S.S. Brown. 1994. Immunofluorescence localization of the unconventional myosin, Myo2p, and the putative kinesin-related protein, Smy1p, to the same regions of polarized growth in Saccharomyces cerevisiae. J. Cell Biol. 125:825-842.
23. Liu, H., and A. Bretscher. 1992. Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transport. J. Cell Biol. 118:285-299.
24. Liu, Q.Y., and W.C. Summers. 1988. Site-directed mutagenesis of a nucleotide-binding domain in HSV-1 thymidine kinase: effects on catalytic activity. Virology. 163:638-642.
25. Logan, K.M., and K.L. Knight. 1993. Mutagenesis of the P-loop motif in the ATP binding site of the RecA protein from Escherichia coli. J. Mol. Biol. 232:1048-1059.
26. Meluh, P.B., and M.D. Rose. 1990. KAR3, a kinesin-related gene required for yeast nuclear fusion. Cell. 60:1029-1041.
27. Morris, R.L., and P.J. Hollenbeck. 1995. Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons. J. Cell Biol. 131: 1315-1326.
28. Mullins, R.D., J.F. Kelleher, and T.D. Pollard. 1996. Actin' like actin? Trends Cell Biol. 6:208-212.
29. Nair, J., H. Muller, M. Peterson, and P. Novick. 1990. Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxy terminal domain. J. Cell Biol. 110:1897-1909.
30. Novick, P., and D. Botstein. 1985. Phenotypic analysis of temperature-sensitive yeast actin mutants. Cell. 40:405-116.
31. Pai, E.F., U. Krengel, G.A. Petsko, R.S. Goody, W. Kabsch, and A. Wittinghofer. 1990. Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35Å resolution: implications for the mechanism of GTP hydrolysis. EMBO J. 9:2351-2359.
32. Plesset, J., J.R. Ludwig, B.S. Cox, and C.S. McLaughlin. 1987. Effect of cell cycle position on thermotolerance in Saccharomyces cerevisiae. J. Bacteriol. 169:779-784.
33. 2+-dependent interaction with the synaptobrevin-synaptophysin complex. J. Cell Biol. 137:1589-1601.
34. Preuss, D., J. Mulholland, A. Franzusoff, N. Segev, and D. Botstein. 1992. Characterization of the Saccharomyces Golgi complex through the cell cycle by immunoelectron microscopy. Mol. Biol. Cell. 3:789-803.
35. Rayment, I., W.R. Rypniewski, K. Schmidt-Bäse, R. Smith, D.R. Tomchick, M.M. Benning, D.A. Winkelmann, G. Wesenberg, and H. Holden. 1993. Three-dimensional structure of myosin subfragment-1: a molecular motor. Science. 261:50-65.
36. Sablin, E.P., F.J. Kull, R. Cooke, R.D. Vale, and R.J. Fletterick. 1996. Crystal structure of the motor domain of the kinesin-related motor ncd. Nature. 380: 555-559.
37. Salminen, A., and P.J. Novick. 1987. A ras-like protein is required for a post-Golgi event in yeast secretion. Cell. 49:527-538.
38. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
39. Saraste, M., P.R. Sibbald, and A. Wittinghofer. 1990. The P-loop - a common motif in ATP-and GTP-binding proteins. Trends Biochem. Sci. 15:430-434.
40. 1-ATPase from yeast. J. Biol. Chem. 269:9424-9428.
41. Sherman, F., G.R. Fink, and J.B. Hicks. 1986. Methods in Yeast Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
42. Sisson, J.C., K.S. Ho, K. Suyama, and M.P. Scott. 1997. Costal2, a novel kinesin-related protein in the hedgehog signaling pathway. Cell 90:235-245.
43. Smith, C.A., and I. Rayment. 1996. Active site comparisons highlight structural similarities between myosin and other P-loop proteins. Biophys. J. 70:1590-1602.
44. Stearns, T., and D. Botstein. 1988. Unlinked noncomplementation: isolation of new conditional-lethal mutations in each of the lubulin genes of Saccharomyces cerevisiae. Genetics. 119:249-260.
45. TerBush, D.R., and P. Novick. 1995. Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. J. Cell Biol. 130:299-312.
46. TerBush, D.R., T. Maurice, D. Roth, and P. Novick. 1996. The exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J. 15:6483-6494.
47. Thomas, J.H., N.F. Neff, and D. Botstein. 1985. Isolation and characterization of mutations in the β-tubulin gene of Saccharomyces cerevisiae. Genetics. 111:715-734.
48. Walch-Solimena, C., R.N. Collins, and P.J. Novick. 1997. Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles. J. Cell Biol. 137:1495-1509.
49. Woehlke, G., A.K. Ruby, C.L. Hart, B. Ly, N. Hom-Booher, and R.D. Vale. 1997. Microtubule interaction site of the kinesin motor. Cell. 90:207-216.
50. Yang, L.T., R.A. Laymon, and L.S.B. Goldstein. 1989. A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. Cell. 56:879-889.