Chromatin elongation factors

Current Opinion in Genetics and Development

Volumn 12, Issue 2, 2002, Pages 156-161

  Svejstrup, Jesper Q ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; ACYLTRANSFERASE; BIOLOGICAL FACTOR; CHROMATIN ELONGATION FACTOR; DEOXYRIBONUCLEASE; DNA; HISTONE ACETYLTRANSFERASE; NAKED DNA; RNA; RNA POLYMERASE II; UNCLASSIFIED DRUG;

CHROMATIN; CHROMATIN STRUCTURE; DNA TEMPLATE; FUNGAL GENETICS; GENETIC TRANSCRIPTION; HUMAN; MAMMAL; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; REVIEW;

MAMMALIA;

EID: 0036531899     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(02)00281-2     Document Type: Review

References (51)

1. Structural changes in nucleosomes during transcription: Strip, split or flip?
2. What happens to nucleosomes during transcription?
3. Transcription through nucleosomes
4. Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones
5. Transcription on nucleosomal templates by RNA polymerase II in vitro: Inhibition of elongation with enhancement of sequence-specific pausing
6. Chromatin transitions during activation and repression of galactose-regulated genes in yeast
7. Eukaryotic RNA polymerase II binds to nucleosome cores from transcribed genes
8. RNA polymerase-specific nucleosome disruption by transcription in vivo
9. Reversible and irreversible changes in nucleosome structure along the c-fos and c-myc oncogenes following inhibition of transcription
10. Supercoiling of the DNA template during transcription
11. Evidence that Spt6p controls chromatin structure by a direct interaction with histones
12. The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins
13. Stimulation of RNA polymerase II elongation by chromosomal protein HMG-14
14. Factors affecting nucleosome structure in transcriptionally active chromatin. Histone acetylation, nascent RNA and inhibitors of RNA synthesis
15. Inhibition of transcription selectively reduces the level of ubiquitinated histone H2B in chromatin
16. Effects of histone tail domains on the rate of transcriptional elongation through a nucleosome
17. Elongator, a multi-subunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation
18. A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme
19. Activator-dependent regulation of transcriptional pausing on nucleosomal templates
20. Disruption of downstream chromatin directed by a transcriptional activator
21. Genetic interactions between TFIIS and the Swi-Snf chromatin-remodeling complex
22. Cockayne syndrome group B protein enhances elongation by RNA polymerase II
23. ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor
24. Mechanisms of transcription-coupled repair
25. The SAGA of Spt proteins and transcriptional analysis in yeast: Past, present, and future
26. Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae
27. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
28. FACT relieves DSIF/NELF-mediated inhibition of transcriptional elongation and reveals functional differences between P-TEFb and TFIIH
29. NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
30. Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro
31. High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: Roles in promoter proximal pausing and transcription elongation
32. Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster
33. A regulator of transcriptional elongation controls vertebrate neuronal development
34. Spt4 modulates Rad26 requirement in transcription-coupled nucleotide excision repair
35. Yeast spt6-140 mutation, affecting chromatin and transcription, preferentially increases recombination in which Rad51p-mediated strand exchange is dispensable
36. RNA polymerase II elongator holoenzyme is composed of two discrete subcomplexes
37. A multiprotein complex that interacts with RNA polymerase II elongator
38. Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae
39. Overlapping roles for the histone acetyltransferase activities of SAGA and elongator in vivo
40. Saccharomyces cerevisiae elongator mutations confer resistance to the Kluyveromyces lactis zymocin
41. Involvement of yeast carboxy-terminal domain kinase I (CTDK-I) in transcription elongation in vivo
42. FACT, a factor that facilitates transcript elongation through nucleosomes
43. The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein
44. A DNA unwinding factor involved in DNA replication in cell-free extracts of Xenopus eggs
45. A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1
46. Interaction of FACT, SSRP1, and the high mobility group (HMG) domain of SSRP1 with DNA damaged by the anticancer drug cisplatin
47. A bipartite yeast SSRP1 analog comprised of Pob3 and Nhp6 proteins modulates transcription
48. Spt16 Pob3 and the HMG protein Nhp6 combine to form the nucleosome-binding factor SPN
49. The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex
50. Purification and characterization of the human Elongator complex
51. Human elongator facilitates RNA polymerase II transcription through chromatin