The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p

Cell

Volumn 103, Issue 3, 2000, Pages 423-433

  Goldmark, Jesse P ^a   Fazzio, Thomas G ^a   Estep, Pete W ^b   Church, George M ^b   Tsukiyama, Toshio ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE; NUCLEASE;

ARTICLE; CHROMATIN STRUCTURE; COMPLEX FORMATION; GENETIC TRANSCRIPTION; MEIOSIS; MITOSIS; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION TERMINATION;

SACCHAROMYCES CEREVISIAE;

EID: 0034721670     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)00134-3     Document Type: Article

References (73)

1. Systematic management and analysis of yeast gene expression data
2. A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains
3. UME6, a negative regulator of meiosis in Saccharomyces cerevisiae, contains a C-terminal Zn2Cys6 binuclear cluster that binds the URS1 DNA sequence in a zinc-dependent manner
4. Interplay between chromatin modifying and remodeling complexes in transcriptional regulation
5. Continuous and widespread roles for the Swi-Snf complex in transcription
6. A family of chromatin remodeling factors related to Williams syndrome transcription factor
7. Bipartite structure of an early meiotic upstream activation sequence from Saccharomyces cerevisiae
8. Positive control of yeast meiotic genes by the negative regulator UME6
9. Chromatin remodeling machines: Similar motors, ulterior motives
10. HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex
11. Gametogenesis in yeast is regulated by a transcriptional cascade dependent on Ndt80
12. The ISWI chromatin remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo
13. The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vlvo
14. Chromatin remodelling at the PHO8 promoter requires SWI-SNF and SAGA at a step subsequent to activator binding
15. Histone deacetylase activity is required for full transcriptional repression by mSin3A
16. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression
17. Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure
18. Dissecting the regulatory circuitry of a eukaryotic genome
19. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
20. ACF, an ISWI-containing and ATP-utilizing chromatin assembly and remodeling factor
21. ATP-facilitated chromatin assembly with a nucleoplasminlike protein from Drosophila melanogaster
22. The yeast UME6 gene is required for both negative and positive transcriptional regulation of phospholipid biosynthetic gene expression
23. Eukaryotic transcription: An interlaced network of transcription factors and chromatin-modifying machines
24. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters
25. Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo
26. Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo
27. A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators
28. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity
29. Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
30. Meiosis and sporulation in Saccharomyces cerevisiae
31. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression
32. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
33. Purification and characterization of a human factor that assembles and remodels chromatin
34. Requirement of RSF and FACT for transcription of chromatin templates in vitro
35. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
36. Repression: Targeting the heart of the matter
37. Control of meiotic gene expression in Saccharomyces cerevisiae
38. Role of nucleosome remodeling factor NURF in transcriptional activation of chromatin
39. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
40. SWI/SNF complex: Dissection of a chromatin remodeling cycle
41. A functional interaction between the C-terminal domain of RNA polymerase II and the negative regulator SIN1
42. Role for ADA/GCN5 products in antagonizing chromatin-mediated transcriptional repression
43. HuCHRAC, a human ISW1 chromatin remodelling complex contains hACF1 and two novel histone-fold proteins
44. Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes
45. Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast
46. Induction of meiosis in Saccharomyces cerevisiae depends on conversion of the transcriptional represssor UmE6 to a positive regulator by its regulated association with the transcriptional activator lme1
47. HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription
48. Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3
49. Role of IME1 expression in regulation of meiosis in Saccharomyces cerevisiae
50. A phylogenetically conserved NAD+-dependent protein deacetylase activity in the sir2 protein family
51. UMF6 is a central component of a developmental regulatory switch controlling meiosis-specific gene expression
52. The language of covalent histone modifications
53. Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast
54. UME6 is a key regulator of nitrogen repression and meiotic development
55. Fundamentally different logic of gene regulation in eukaryotes and prokaryotes
56. Histone acetylation and transcriptional regulatory mechanisms
57. The nucleosome remodeling complex, Snf/Swi, is required for the maintenance of transcription in vivo and is partially redundant with the histone acetyltransferase, Gcn5
58. Whole-genome expression analysis of snf/swi mutants of saccharomyces cerevisiae
59. The regulation of gene activity by histones and the histone deacetylase RPD3
60. Role of UME6 in transcriptional regulation of a DNA repair gene in Saccharomyces cerevisiae
61. An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing
62. Saccharomyces cerevisiae gene ISW2 encodes a microtubule-interacting protein required for premeiotic DNA replication
63. ISWI, a member of the SWI2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor
64. Characterization of the imitation switch subfamily of ATP-dependent chromatin-remodeling factors in Saccharomyces cerevisiae
65. Chromatin remodeling and transcription
66. Purification and properties of an ATP-dependent nucleosome remodeling factor
67. The 'dark side' of chromatin remodeling: Repressive effects on transcription
68. Chromatin-remodelling factor CHRAC contains the ATPases ISW1 and topoisomerase II
69. RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae
70. Transcriptional regulation: SWitching circuitry
71. Genome-wide expression monitoring in Saccharomyces cerevisiae
72. Alteration of nucleosome structure as a mechanism of transcriptional regulation
73. A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools