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Volumn 178, Issue 2, 2003, Pages 97-106

Dose-dependent effects of acute exercise on PKC levels in rat heart: Is PKC the heart's prophylactic?

Author keywords

Cardioprotection; Exercise; mRNA; Myocardium; PKC; Protein

Indexed keywords

MESSENGER RNA; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON;

EID: 0037495856     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.2003.01131.x     Document Type: Conference Paper
Times cited : (19)

References (57)
  • 1
    • 0029923860 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase
    • 2+/calmodulin-dependent protein kinase. Mol Cell Biochem 155, 91-103.
    • (1996) Mol Cell Biochem , vol.155 , pp. 91-103
    • Allen, B.G.1    Katz, S.2
  • 2
    • 0037177860 scopus 로고    scopus 로고
    • Nitric oxide (NO) induces nitration of protein kinase Cε (PKCε), facilitating PKCε translocadon via enhanced PKCε-RACK2 interactions
    • Balafanova, Z., Bolli, R., Zhang, J. et al. 2002. Nitric oxide (NO) induces nitration of protein kinase Cε (PKCε), facilitating PKCε translocadon via enhanced PKCε-RACK2 interactions. J Biol Chem 277, 15 021-15 027.
    • (2002) J Biol Chem , vol.277 , pp. 15021-15027
    • Balafanova, Z.1    Bolli, R.2    Zhang, J.3
  • 3
    • 0029027436 scopus 로고
    • Involvement of protein kinase c in the delayed cytoprotection following sublethal ischemia in rabbit myocardium
    • Baxter, G.F., Goma, F.M. & Yellon, D.M. 1995. Involvement of protein kinase c in the delayed cytoprotection following sublethal ischemia in rabbit myocardium. Br J Pharmacol 115, 222-224.
    • (1995) Br J Pharmacol , vol.115 , pp. 222-224
    • Baxter, G.F.1    Goma, F.M.2    Yellon, D.M.3
  • 4
    • 0026668510 scopus 로고
    • Exercise training improves cardiac function after ischemia in the isolated working rat heart
    • Bowles, D.K., Farrar, R.D. & Starnes, J.W. 1992. Exercise training improves cardiac function after ischemia in the isolated working rat heart. Am J Physiol 263, H804-H809.
    • (1992) Am J Physiol , vol.263
    • Bowles, D.K.1    Farrar, R.D.2    Starnes, J.W.3
  • 5
    • 0032917447 scopus 로고    scopus 로고
    • 2+-sensitive isoforms in the failing human heart
    • 2+-sensitive isoforms in the failing human heart. Circulation 99, 384-391.
    • (1999) Circulation , vol.99 , pp. 384-391
    • Bowling, N.1    Walsh, R.A.2    Song, G.3
  • 6
    • 0030696157 scopus 로고    scopus 로고
    • Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates
    • Bowman, J.C., Steinberg, S.F., Jiang, T., Greenen, D.L., Fishman, G.I. & Buttrick, P.M. 1997. Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates. J Clin Invest 100, 2189-2195.
    • (1997) J Clin Invest , vol.100 , pp. 2189-2195
    • Bowman, J.C.1    Steinberg, S.F.2    Jiang, T.3    Greenen, D.L.4    Fishman, G.I.5    Buttrick, P.M.6
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. 1976. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248-251.
    • (1976) Anal Biochem , vol.72 , pp. 248-251
    • Bradford, M.M.1
  • 8
    • 0037018154 scopus 로고    scopus 로고
    • PKCα regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2)
    • Braz, J.C., Bueno, O.F., DeWindt, L.J. & Molkentin J.D. 2002. PKCα regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2). J Cell Biol 156, 905-919.
    • (2002) J Cell Biol , vol.156 , pp. 905-919
    • Braz, J.C.1    Bueno, O.F.2    DeWindt, L.J.3    Molkentin, J.D.4
  • 9
    • 0035949580 scopus 로고    scopus 로고
    • Opposing cardioprotective actions and patrallel hypertrophic effects of δ PKC and ε PKC
    • Chen, L., Hahn, H.S., Wu, G. et al. 2001. Opposing cardioprotective actions and patrallel hypertrophic effects of δ PKC and ε PKC. Proc Natl Acad Sci USA 98, 11 114-11 119.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11114-11119
    • Chen, L.1    Hahn, H.S.2    Wu, G.3
  • 10
    • 13044274187 scopus 로고    scopus 로고
    • Sustained in vivo cardiac protection by a rationally designed peptide that causes ε protein kinase C translocation
    • Dorn, G.W.I., Souroujon, M.C., Liron, T. et al. 1999. Sustained in vivo cardiac protection by a rationally designed peptide that causes ε protein kinase C translocation. Proc Natl Acad Sci USA 96, 12 798-12 803.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12798-12803
    • Dorn, G.W.I.1    Souroujon, M.C.2    Liron, T.3
  • 11
    • 0025294351 scopus 로고
    • Left ventricular functional capacity in the endurance-trained rodent
    • Fitzsimons, D.P., Bodell, P.W., Herrick, R.E. & Baldwin, K.M. 1990. Left ventricular functional capacity in the endurance-trained rodent. J Appl Physiol 69, 305-312.
    • (1990) J Appl Physiol , vol.69 , pp. 305-312
    • Fitzsimons, D.P.1    Bodell, P.W.2    Herrick, R.E.3    Baldwin, K.M.4
  • 12
    • 0034976736 scopus 로고    scopus 로고
    • Essential activation of PKC-delta in opioid-initiated cardioprotection
    • Fryer, R.M., Wang, Y., Hsu, A.K. & Gross, G.J. 2001. Essential activation of PKC-delta in opioid-initiated cardioprotection. Am J Physiol 280, H1346-H1353.
    • (2001) Am J Physiol , vol.280
    • Fryer, R.M.1    Wang, Y.2    Hsu, A.K.3    Gross, G.J.4
  • 13
    • 0036150173 scopus 로고    scopus 로고
    • PKC-delta inhibition does not block preconditioning-induced preservation in mitochondrial ATP synthesis and infarct size reduction in rats
    • Fryer, R.M., Hsu, A.K., Wang, Y., Henry, M., Eells, J. & Gross, G.J. 2002. PKC-delta inhibition does not block preconditioning-induced preservation in mitochondrial ATP synthesis and infarct size reduction in rats. Basic Res Cardiol 97, 47-54.
    • (2002) Basic Res Cardiol , vol.97 , pp. 47-54
    • Fryer, R.M.1    Hsu, A.K.2    Wang, Y.3    Henry, M.4    Eells, J.5    Gross, G.J.6
  • 14
    • 0030609162 scopus 로고    scopus 로고
    • A selective ε protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death
    • Gray, M.O., Karliner, J.S. & Mochly-Rosen, D. 1997. A selective ε protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death. J Biol Chem 272, 30 945-30 951.
    • (1997) J Biol Chem , vol.272 , pp. 30945-30951
    • Gray, M.O.1    Karliner, J.S.2    Mochly-Rosen, D.3
  • 16
    • 0037131326 scopus 로고    scopus 로고
    • Ischemic protection and myofibrillar cardiomyopathy: Dose-dependent effects of in vivo δ PKC inhibition
    • Hahn, H.S., Yussman, M.G., Toyokawa, T. et al. 2002. Ischemic protection and myofibrillar cardiomyopathy: dose-dependent effects of in vivo δ PKC inhibition. Circ Res 91, 741-748.
    • (2002) Circ Res , vol.91 , pp. 741-748
    • Hahn, H.S.1    Yussman, M.G.2    Toyokawa, T.3
  • 17
    • 0035031223 scopus 로고    scopus 로고
    • Increased contractility and altered Ca(2+) transients of mouse hearts conditionally expressing PKCbeta
    • Huang, L., Wolska, B.M., Montgomery, D.E., Burkart, E.M., Buttrick, P.M. & Solaro, R.J. 2001. Increased contractility and altered Ca(2+) transients of mouse hearts conditionally expressing PKCbeta. Am J Physiol 280, C1114-C1120.
    • (2001) Am J Physiol , vol.280
    • Huang, L.1    Wolska, B.M.2    Montgomery, D.E.3    Burkart, E.M.4    Buttrick, P.M.5    Solaro, R.J.6
  • 18
    • 33750865610 scopus 로고    scopus 로고
    • Ischemic preconditioning translocates PKC-delta and -epsilon, which mediate functional protection in isolated rat heart
    • Kawamura, S., Yoshida, K., Miura, T., Mizukami, Y. & Matsuzaki, M. 1998. Ischemic preconditioning translocates PKC-delta and -epsilon, which mediate functional protection in isolated rat heart. Am J Physiol 275, H2266-H2271.
    • (1998) Am J Physiol , vol.275
    • Kawamura, S.1    Yoshida, K.2    Miura, T.3    Mizukami, Y.4    Matsuzaki, M.5
  • 19
    • 0035853423 scopus 로고    scopus 로고
    • Ischemic preconditioning upregulates vascular endothelial growth factors, mRNA expression and neovascularization via nuclear translocation of protein kinase C ε in the rat ischemic myocardium
    • Kawata, H., Yoshida, K., Kawamoto, A. et al. 2001. Ischemic preconditioning upregulates vascular endothelial growth factors, mRNA expression and neovascularization via nuclear translocation of protein kinase C ε in the rat ischemic myocardium. Circ Res 88, 696-704.
    • (2001) Circ Res , vol.88 , pp. 696-704
    • Kawata, H.1    Yoshida, K.2    Kawamoto, A.3
  • 20
    • 0030462811 scopus 로고    scopus 로고
    • 1-adrenergic inotropic responsiveness in rats with mild hypertension
    • 1-adrenergic inotropic responsiveness in rats with mild hypertension. Am J Physiol 271, H2599-H2608.
    • (1996) Am J Physiol , vol.271
    • Korzick, D.H.1    Moore, R.2
  • 23
    • 0036299608 scopus 로고    scopus 로고
    • Adenosine A(1) receptor mediates late preconditioning via activation of PKC-delta signaling pathway
    • Kudo, M., Wang, Y., Xu, M., Ayub, A. & Ashraf, M. 2002. Adenosine A(1) receptor mediates late preconditioning via activation of PKC-delta signaling pathway. Am J Physiol 283, H296-H301.
    • (2002) Am J Physiol , vol.283
    • Kudo, M.1    Wang, Y.2    Xu, M.3    Ayub, A.4    Ashraf, M.5
  • 24
    • 0027222962 scopus 로고
    • Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia
    • Kuzuya, T., Hoshida, S., Yamashita, N. et al. 1993. Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia. Circ Res 72, 1293-1299.
    • (1993) Circ Res , vol.72 , pp. 1293-1299
    • Kuzuya, T.1    Hoshida, S.2    Yamashita, N.3
  • 26
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study
    • Levy, D., Garrison, R.J., Savage, D.D., Kannel, W.B. & Castelli, W.P. 1990. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 322, 1561-1566.
    • (1990) N Engl J Med , vol.322 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5
  • 27
    • 0034814378 scopus 로고    scopus 로고
    • Preconditioning attenuates apoptosis and necrosis: Role of protein kinase C epsilon and -delta isoforms
    • Liu, H., McPherson, B.C. & Yao, Z. 2001. Preconditioning attenuates apoptosis and necrosis: role of protein kinase C epsilon and -delta isoforms. Am J Physiol 281, H404-H410.
    • (2001) Am J Physiol , vol.281
    • Liu, H.1    McPherson, B.C.2    Yao, Z.3
  • 28
    • 0027163384 scopus 로고
    • Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial function
    • Marber, M.S., Latchman, D.S., Walker, J.M. & Yellon, D.M. 1993. Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial function. Circulation 88, 1264-1272.
    • (1993) Circulation , vol.88 , pp. 1264-1272
    • Marber, M.S.1    Latchman, D.S.2    Walker, J.M.3    Yellon, D.M.4
  • 29
    • 0031127633 scopus 로고    scopus 로고
    • Protein kinase C isoform diversity in preconditioning
    • Meldrum, D.R., Cleveland, J.C.J., Meng, X. et al. 1997. Protein kinase C isoform diversity in preconditioning. J Surg Res 69, 183-187.
    • (1997) J Surg Res , vol.69 , pp. 183-187
    • Meldrum, D.R.1    Cleveland, J.C.J.2    Meng, X.3
  • 30
    • 0028908855 scopus 로고
    • Preconditioning of isolated rat heart is mediated by protein kinase C
    • Mitchell, M.B., Meng, X., Ao, L., Brown, J.M., Harken, A.H. & Banerjee, A. 1995. Preconditioning of isolated rat heart is mediated by protein kinase C. Circ Res 76, 73-81.
    • (1995) Circ Res , vol.76 , pp. 73-81
    • Mitchell, M.B.1    Meng, X.2    Ao, L.3    Brown, J.M.4    Harken, A.H.5    Banerjee, A.6
  • 31
    • 0028938152 scopus 로고
    • Localization of protein kinases by anchoring proteins: A theme in signal transduction
    • Mochly-Rosen, D. 1995. Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science 268, 247-251.
    • (1995) Science , vol.268 , pp. 247-251
    • Mochly-Rosen, D.1
  • 32
    • 0027212732 scopus 로고
    • Chronic exercise alters contractility and morphology of isolated rat cardiac myocytes
    • Moore, R.L., Musch, T.I., Yelamarty, R.V. et al. 1993. Chronic exercise alters contractility and morphology of isolated rat cardiac myocytes. Am J Physiol 264, C1180-C1189.
    • (1993) Am J Physiol , vol.264
    • Moore, R.L.1    Musch, T.I.2    Yelamarty, R.V.3
  • 33
    • 0028811653 scopus 로고
    • Protein kinase C: Structure, function and regulation
    • Newton, A.C. 1995. Protein kinase C: structure, function and regulation. J Biol Chem 270, 28 495-28 498.
    • (1995) J Biol Chem , vol.270 , pp. 28495-28498
    • Newton, A.C.1
  • 34
    • 0036299756 scopus 로고    scopus 로고
    • ATP channel occurs downstream of PKC-ε activation in the mechanism of preconditioning
    • ATP channel occurs downstream of PKC-ε activation in the mechanism of preconditioning. Am J Physiol 283, H440-H447.
    • (2002) Am J Physiol , vol.283
    • Ohnuma, Y.1    Miura, T.2    Miki, T.3
  • 35
    • 0035662009 scopus 로고    scopus 로고
    • Enhanced PKCII translocation and PKCβII-RACK1 interactions in PKCε-induced heart failure: Role for RACK1
    • Pass, J.M., Gao, J., Jones, W.K. et al. 2001. Enhanced PKCII translocation and PKCβII-RACK1 interactions in PKCε-induced heart failure: role for RACK1. Am J Physiol 281, H2500-H2510.
    • (2001) Am J Physiol , vol.281
    • Pass, J.M.1    Gao, J.2    Jones, W.K.3
  • 36
    • 0030872474 scopus 로고    scopus 로고
    • Ischemic preconditioning induces selective translocation of protein kinase C isoforms ε and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity
    • Ping, P., Ahang, J., Qiu, Y. et al. 1997. Ischemic preconditioning induces selective translocation of protein kinase C isoforms ε and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity. Circ Res 81, 404-414.
    • (1997) Circ Res , vol.81 , pp. 404-414
    • Ping, P.1    Ahang, J.2    Qiu, Y.3
  • 37
    • 0032523962 scopus 로고    scopus 로고
    • Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that ε is the isoform involved
    • Qiu, Y., Ping, P. & Tang, X.L. 1998. Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that ε is the isoform involved. J Clin Invest 101, 2182-2198.
    • (1998) J Clin Invest , vol.101 , pp. 2182-2198
    • Qiu, Y.1    Ping, P.2    Tang, X.L.3
  • 38
    • 0033844365 scopus 로고    scopus 로고
    • The alpha (1)-adrenoceptor subvtype and protein kinase C isosyme-dependence of norepinephrine's actions in cardiomyocytes
    • Rohde, S., Sabri, A., Kamasamudran, R. & Steinberg, S.F. 2000. The alpha (1)-adrenoceptor subvtype and protein kinase C isosyme-dependence of norepinephrine's actions in cardiomyocytes. J Mol Cell Cardiol 32, 1193-1209.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 1193-1209
    • Rohde, S.1    Sabri, A.2    Kamasamudran, R.3    Steinberg, S.F.4
  • 39
    • 0028158867 scopus 로고
    • Protein kinase C isoform expression and regulation in the developing rat heart
    • Rybin, V.O. & Steinberg, S.F. 1994. Protein kinase C isoform expression and regulation in the developing rat heart. Circ Res 74, 299-309.
    • (1994) Circ Res , vol.74 , pp. 299-309
    • Rybin, V.O.1    Steinberg, S.F.2
  • 40
    • 0032514223 scopus 로고    scopus 로고
    • Modulation of mitochondrial ATP-dependent K channels by protein kinase C
    • Sato, T., O'Bourke, B. & Marban, E. 1998. Modulation of mitochondrial ATP-dependent K channels by protein kinase C. Circ Res 83, 110-114.
    • (1998) Circ Res , vol.83 , pp. 110-114
    • Sato, T.1    O'Bourke, B.2    Marban, E.3
  • 41
    • 0021239240 scopus 로고
    • Cardiac conditioning ameliorates cardiac dysfunction associated with renal hypertension in rats
    • Schaible, T.F., Ciambrone, G.J., Capasso, J.M. & Scheuer, J. 1984. Cardiac conditioning ameliorates cardiac dysfunction associated with renal hypertension in rats. J Clin Invest 73, 1086-1094.
    • (1984) J Clin Invest , vol.73 , pp. 1086-1094
    • Schaible, T.F.1    Ciambrone, G.J.2    Capasso, J.M.3    Scheuer, J.4
  • 42
    • 0022550803 scopus 로고
    • Chronic swimming reverses cardiac dysfunction and myosin abnormalities in hypertensive rats
    • Schaible, T.F., Malhorta, A., Ciambrone, G.J. & Scheuer, J. 1986. Chronic swimming reverses cardiac dysfunction and myosin abnormalities in hypertensive rats. J Appl Physiol 60, 1435-1441.
    • (1986) J Appl Physiol , vol.60 , pp. 1435-1441
    • Schaible, T.F.1    Malhorta, A.2    Ciambrone, G.J.3    Scheuer, J.4
  • 43
    • 0036081393 scopus 로고    scopus 로고
    • Protein kinase C-delta modulates apoptosis induced by hyperglycemia in adult ventricular myocytes
    • Shizukuda, Y., Reyland, M.E. & Buttrick, P.M. 2002. Protein kinase C-delta modulates apoptosis induced by hyperglycemia in adult ventricular myocytes. Am J Physiol 282, H1625-H1634.
    • (2002) Am J Physiol , vol.282
    • Shizukuda, Y.1    Reyland, M.E.2    Buttrick, P.M.3
  • 44
    • 0036244065 scopus 로고    scopus 로고
    • Regulation of the isozymes of protein kinase C in the surviving rat myocardium after myocardial infarction: Distinct modulation for PKC-alpha and for PKC delta
    • Simonis, G., Honold, J., Schwarz, K., Braun, M.U. & Strasser, R.H. 2002. Regulation of the isozymes of protein kinase C in the surviving rat myocardium after myocardial infarction: distinct modulation for PKC-alpha and for PKC delta. Basic Res Cardiol 97, 223-231.
    • (2002) Basic Res Cardiol , vol.97 , pp. 223-231
    • Simonis, G.1    Honold, J.2    Schwarz, K.3    Braun, M.U.4    Strasser, R.H.5
  • 45
    • 33750742805 scopus 로고    scopus 로고
    • Function and bioenergetics in isolated perfused trained rat hearts
    • Spencer, R., Buttrick, P.M. & Ingwell, J. 1997. Function and bioenergetics in isolated perfused trained rat hearts. Am J Physiol 272, H409-H417.
    • (1997) Am J Physiol , vol.272
    • Spencer, R.1    Buttrick, P.M.2    Ingwell, J.3
  • 46
    • 0035005389 scopus 로고    scopus 로고
    • Post-ischemic PKC inhibition impairs myocardial calcium handling and increases contractile protein calcium sensitivity
    • Stamm, C., Friehs, I., Cowan, D.B. et al. 2001. Post-ischemic PKC inhibition impairs myocardial calcium handling and increases contractile protein calcium sensitivity. Cardiovasc Res 51, 108-121.
    • (2001) Cardiovasc Res , vol.51 , pp. 108-121
    • Stamm, C.1    Friehs, I.2    Cowan, D.B.3
  • 47
    • 0034705485 scopus 로고    scopus 로고
    • Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy
    • Takeishi, Y., Ping, P., Bolli, R., Kirkpatrick, D.L., Hoit, B.D. & Walsh, R.A. 2000. Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy. Circ Res 86, 1218-1223.
    • (2000) Circ Res , vol.86 , pp. 1218-1223
    • Takeishi, Y.1    Ping, P.2    Bolli, R.3    Kirkpatrick, D.L.4    Hoit, B.D.5    Walsh, R.A.6
  • 48
    • 0033612370 scopus 로고    scopus 로고
    • 2+ overload injury in rat myocardium
    • 2+ overload injury in rat myocardium. Circ Res 84, 1156-1165.
    • (1999) Circ Res , vol.84 , pp. 1156-1165
    • Wang, Y.1    Ashraf, M.2
  • 49
    • 0033570269 scopus 로고    scopus 로고
    • + channel for cardiac protection against ischemic injury is dependent on protein kinase C activity
    • + channel for cardiac protection against ischemic injury is dependent on protein kinase C activity. Circ Res 85, 731-741.
    • (1999) Circ Res , vol.85 , pp. 731-741
    • Wang, Y.1    Hirai, K.2    Ashraf, M.3
  • 50
    • 0036724631 scopus 로고    scopus 로고
    • Expression of connective tissue growth and diabetes
    • Way, K.J., Isshiki, K., Suzuma, K. et al. 2002. Expression of connective tissue growth and diabetes. Diabetes 51, 2709-2718.
    • (2002) Diabetes , vol.51 , pp. 2709-2718
    • Way, K.J.1    Isshiki, K.2    Suzuma, K.3
  • 51
    • 0033532699 scopus 로고    scopus 로고
    • Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation
    • Yamashita, N., Hoshida, S. & Otsu, K. 1999. Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation. J Exp Med 189, 1699-1706.
    • (1999) J Exp Med , vol.189 , pp. 1699-1706
    • Yamashita, N.1    Hoshida, S.2    Otsu, K.3
  • 52
    • 0034768328 scopus 로고    scopus 로고
    • Exercise directly enhances myocardial tolerance to ischemia-repurfusion injury in the rat through a protein kinase C mediated mechanism
    • Yamashita, N., Baxter, G.F. & Yellon, D.M. 2001. Exercise directly enhances myocardial tolerance to ischemia-repurfusion injury in the rat through a protein kinase C mediated mechanism. Heart 85, 331-336.
    • (2001) Heart , vol.85 , pp. 331-336
    • Yamashita, N.1    Baxter, G.F.2    Yellon, D.M.3
  • 53
    • 0032128254 scopus 로고    scopus 로고
    • In vivo phosphorylation of cardiac troponin I by protein kinase Cβ2 decreases cardiomyocytes calcium responsiveness and contractility in transgenic mouse hearts
    • Yasuchika, T., Chu, G., Kirkpatrick, D.L. et al. 1998. In vivo phosphorylation of cardiac troponin I by protein kinase Cβ2 decreases cardiomyocytes calcium responsiveness and contractility in transgenic mouse hearts. J Clin Invest 102, 72-78.
    • (1998) J Clin Invest , vol.102 , pp. 72-78
    • Yasuchika, T.1    Chu, G.2    Kirkpatrick, D.L.3
  • 54
    • 0030574041 scopus 로고    scopus 로고
    • Translocation of protein kinase C-α,δ, and ε isoforms in ischemic rat heart
    • Yoshida, K., Hirata, T., Akita, Y. et al. 1996. Translocation of protein kinase C-α,δ, and ε isoforms in ischemic rat heart. Biochimica et Biophysica Acta 1317, 36-44.
    • (1996) Biochimica et Biophysica Acta , vol.1317 , pp. 36-44
    • Yoshida, K.1    Hirata, T.2    Akita, Y.3
  • 55
    • 0036260822 scopus 로고    scopus 로고
    • Role of nitric-oxide synthase, free radicals, and protein kinase C delta in opioid-induced cardioprotection
    • Zhang, H.Y., McPherson, B.C., Liu, H. et al. 2002. Role of nitric-oxide synthase, free radicals, and protein kinase C delta in opioid-induced cardioprotection. J Pharmacol Exp Ther 301, 1012-1019.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 1012-1019
    • Zhang, H.Y.1    McPherson, B.C.2    Liu, H.3
  • 56
    • 0032483345 scopus 로고    scopus 로고
    • The expression of constitutively active isotopes of protein kinase C to investigate preconditioning
    • Zhao, J., Renner, O., Wightman, L. et al. 1998. The expression of constitutively active isotopes of protein kinase C to investigate preconditioning. J Biol Chem 273, 23 072-23 079.
    • (1998) J Biol Chem , vol.273 , pp. 23072-23079
    • Zhao, J.1    Renner, O.2    Wightman, L.3
  • 57
    • 0036302685 scopus 로고    scopus 로고
    • Moderate alcohol consumption induces sustained cardiac protection by activating PKC-ε and Akt
    • Zhou, H.Z., Karliner, J.S. & Gray, M.O. 2002. Moderate alcohol consumption induces sustained cardiac protection by activating PKC-ε and Akt. Am J Physiol 283, H165-H174.
    • (2002) Am J Physiol , vol.283
    • Zhou, H.Z.1    Karliner, J.S.2    Gray, M.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.