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Volumn 101, Issue 10, 1998, Pages 2182-2198

Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that ε is the isoform involved

Author keywords

Chelerythrine; Myocardial ischemia; Myocardial reperfusion; PKC isoform; PKC isoform

Indexed keywords

CHELERYTHRINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

EID: 0032523962     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI1258     Document Type: Article
Times cited : (151)

References (50)
  • 1
    • 0027222962 scopus 로고
    • Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia and myocardial antioxidant enzymes
    • Kuzuya, T., S. Hoshida, N. Yamashita, H. Fuji, H. Oe, M. Hori, N. Taniguchi, T. Kamada, and M, Tada. 1993. Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia and myocardial antioxidant enzymes. Circ. Res. 72:1293-1299.
    • (1993) Circ. Res. , vol.72 , pp. 1293-1299
    • Kuzuya, T.1    Hoshida, S.2    Yamashita, N.3    Fuji, H.4    Oe, H.5    Hori, M.6    Taniguchi, N.7    Kamada, T.8    Tada, M.9
  • 2
    • 0027163384 scopus 로고
    • Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction
    • Marber, M.S., D.S. Latchman, J.M. Walker, and D.M. Yellon. 1993. Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction. Circulation. 88:1264-1272.
    • (1993) Circulation , vol.88 , pp. 1264-1272
    • Marber, M.S.1    Latchman, D.S.2    Walker, J.M.3    Yellon, D.M.4
  • 3
    • 0028641295 scopus 로고
    • Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning
    • Baxter, G.F., M.S. Marber, V.C. Patel, and D.M. Yellon. 1994. Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning. Circulation. 90:2993-3000.
    • (1994) Circulation , vol.90 , pp. 2993-3000
    • Baxter, G.F.1    Marber, M.S.2    Patel, V.C.3    Yellon, D.M.4
  • 4
    • 0028816976 scopus 로고
    • Late preconditioning against myocardial stunning. An endogenous protective mechanism that confers resistance to postischemic dysfunction 24 h after brief ischemia in conscious pigs
    • Sun, J.Z., X.L. Tang, A.A. Knowlton, S.W. Park, Y. Qiu, and R. Bolli. 1995. Late preconditioning against myocardial stunning. An endogenous protective mechanism that confers resistance to postischemic dysfunction 24 h after brief ischemia in conscious pigs. J. Clin. Invest. 95:388-403.
    • (1995) J. Clin. Invest. , vol.95 , pp. 388-403
    • Sun, J.Z.1    Tang, X.L.2    Knowlton, A.A.3    Park, S.W.4    Qiu, Y.5    Bolli, R.6
  • 5
    • 0029027436 scopus 로고
    • Involvement of protein kinase C in the delayed cytoprotection following sublethal ischaemia in rabbit myocardium
    • Baxter, G.F., F.M. Goma, and D.M. Yellon. 1995. Involvement of protein kinase C in the delayed cytoprotection following sublethal ischaemia in rabbit myocardium. Br. J. Pharmacol. 115:222-224.
    • (1995) Br. J. Pharmacol. , vol.115 , pp. 222-224
    • Baxter, G.F.1    Goma, F.M.2    Yellon, D.M.3
  • 6
    • 0029822231 scopus 로고    scopus 로고
    • Time-course of late preconditioning against myocardial stunning in conscious pigs
    • Tang, X.L., Y. Qiu, S.W. Park, J.Z. Sun, A. Kalya, and R. Bolli. 1996. Time-course of late preconditioning against myocardial stunning in conscious pigs. Circ. Res. 79:424-434.
    • (1996) Circ. Res. , vol.79 , pp. 424-434
    • Tang, X.L.1    Qiu, Y.2    Park, S.W.3    Sun, J.Z.4    Kalya, A.5    Bolli, R.6
  • 7
    • 0030026058 scopus 로고    scopus 로고
    • Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs
    • Sun, J.Z., X.L. Tang, S.W. Park, Y. Qiu, J.F. Turrens, and R. Bolli. 1996. Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs. J. Clin. Invest. 47:562-576.
    • (1996) J. Clin. Invest. , vol.47 , pp. 562-576
    • Sun, J.Z.1    Tang, X.L.2    Park, S.W.3    Qiu, Y.4    Turrens, J.F.5    Bolli, R.6
  • 8
    • 0030872474 scopus 로고    scopus 로고
    • Ischemic preconditioning induces selective translocation of protein kinase C isoforms ∈ and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity
    • Ping, P., J. Zhang, Y. Qiu, X.L. Tang, S. Manchikalapudi, X. Cao, and R. Bolli. 1997. Ischemic preconditioning induces selective translocation of protein kinase C isoforms ∈ and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity. Circ. Res. 81:404-414.
    • (1997) Circ. Res. , vol.81 , pp. 404-414
    • Ping, P.1    Zhang, J.2    Qiu, Y.3    Tang, X.L.4    Manchikalapudi, S.5    Cao, X.6    Bolli, R.7
  • 10
    • 0030955587 scopus 로고    scopus 로고
    • Evidence that late preconditioning against myocardial stunning in conscious rabbits is triggered by the generation of nitric oxide
    • Bolli, R., Z.A. Bhatti, X.L. Tang, Y. Qiu, Q. Zhang, Y. Guo, and A.K. Jadoon. 1997. Evidence that late preconditioning against myocardial stunning in conscious rabbits is triggered by the generation of nitric oxide. Circ. Res. 81: 42-52.
    • (1997) Circ. Res. , vol.81 , pp. 42-52
    • Bolli, R.1    Bhatti, Z.A.2    Tang, X.L.3    Qiu, Y.4    Zhang, Q.5    Guo, Y.6    Jadoon, A.K.7
  • 11
    • 33751268691 scopus 로고    scopus 로고
    • Role of adenosine receptors in late preconditioning against myocardial stunning in conscious rabbits
    • Maldonado, C., Y. Qiu, X.L. Tang, M.V. Cohen, J. Auchampach, and R. Bolli. 1997. Role of adenosine receptors in late preconditioning against myocardial stunning in conscious rabbits. Am. J. Physiol. 273:H1324-H1332.
    • (1997) Am. J. Physiol. , vol.273
    • Maldonado, C.1    Qiu, Y.2    Tang, X.L.3    Cohen, M.V.4    Auchampach, J.5    Bolli, R.6
  • 12
    • 0030790462 scopus 로고    scopus 로고
    • Characterization of the infarct-limiting effect of delayed preconditioning: Timecourse and dose-dependency studies in rabbit myocardium
    • Baxter, G.F., F.M. Goma, and D.M. Yellon. 1997. Characterization of the infarct-limiting effect of delayed preconditioning: timecourse and dose-dependency studies in rabbit myocardium. Basic Res. Cardiol. 92:159-167.
    • (1997) Basic Res. Cardiol. , vol.92 , pp. 159-167
    • Baxter, G.F.1    Goma, F.M.2    Yellon, D.M.3
  • 14
    • 0030777615 scopus 로고    scopus 로고
    • The protective effects of late preconditioning against myocardial stunning in conscious rabbits are mediated by nitric oxide synthase: Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning
    • Bolli, R., S. Manchikalapudi, X.L. Tang, H. Takano, Y. Qiu, Y. Guo, Q. Zhang, and A.K. Jadoon. 1997. The protective effects of late preconditioning against myocardial stunning in conscious rabbits are mediated by nitric oxide synthase: evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning. Circ. Res. 81:1094-1107.
    • (1997) Circ. Res. , vol.81 , pp. 1094-1107
    • Bolli, R.1    Manchikalapudi, S.2    Tang, X.L.3    Takano, H.4    Qiu, Y.5    Guo, Y.6    Zhang, Q.7    Jadoon, A.K.8
  • 15
    • 0032483128 scopus 로고    scopus 로고
    • Nitric oxide synthase is the mediator of late preconditioning against myocardial infarction in conscious rabbits
    • In press
    • Takano, H., S. Manchikalapudi, X.L. Tang, Y. Qiu, A. Rizvi, A.K. Jadoon, Q. Zhang, and R. Bolli. 1998. Nitric oxide synthase is the mediator of late preconditioning against myocardial infarction in conscious rabbits. Circulation. In press.
    • (1998) Circulation
    • Takano, H.1    Manchikalapudi, S.2    Tang, X.L.3    Qiu, Y.4    Rizvi, A.5    Jadoon, A.K.6    Zhang, Q.7    Bolli, R.8
  • 16
    • 0029013005 scopus 로고
    • Preconditioning during ischemia
    • Cohen, M.V., and J.M. Downey. 1995. Preconditioning during ischemia. Cardiol. Rev. 3:137-149.
    • (1995) Cardiol. Rev. , vol.3 , pp. 137-149
    • Cohen, M.V.1    Downey, J.M.2
  • 17
    • 0026507220 scopus 로고
    • 1-Receptor-independent activation of protein kinase C in acute myocardial ischemia. Mechanisms for sensitization of the adenylyl cyclase system
    • 1-Receptor-independent activation of protein kinase C in acute myocardial ischemia. Mechanisms for sensitization of the adenylyl cyclase system. Circ. Res. 70:1304-1312.
    • (1992) Circ. Res. , vol.70 , pp. 1304-1312
    • Strasser, R.H.1    Braun-Dullaeus, R.2    Walendzik, H.3    Marquetant, R.4
  • 18
    • 0028643654 scopus 로고
    • Chelerythrine, a highly selective protein kinase C inhibitor, blocks the anti infarct effect of ischemic preconditioning in rabbit hearts
    • Liu, Y., M.V. Cohen, and J.M. Downey. 1994. Chelerythrine, a highly selective protein kinase C inhibitor, blocks the anti infarct effect of ischemic preconditioning in rabbit hearts. Cardiovasc. Drugs Ther. 8:881-882.
    • (1994) Cardiovasc. Drugs Ther. , vol.8 , pp. 881-882
    • Liu, Y.1    Cohen, M.V.2    Downey, J.M.3
  • 19
    • 0028287617 scopus 로고
    • Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium
    • Liu, Y., K. Ytrehus, and J.M. Downey. 1994. Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium. J. Mol. Cell Cardiol. 26:661-668.
    • (1994) J. Mol. Cell Cardiol. , vol.26 , pp. 661-668
    • Liu, Y.1    Ytrehus, K.2    Downey, J.M.3
  • 20
    • 0028348870 scopus 로고
    • Preconditioning protects ischemic rabbit heart by protein kinase C activation
    • Ytrehus, K., Y. Liu, and J.M. Downey. 1994. Preconditioning protects ischemic rabbit heart by protein kinase C activation. Am. J. Physiol. 266: H1145-H1152.
    • (1994) Am. J. Physiol. , vol.266
    • Ytrehus, K.1    Liu, Y.2    Downey, J.M.3
  • 21
    • 0027980893 scopus 로고
    • Protein kinase C: Its role in ischemic preconditioning in the rat
    • Speechly-Dick, M.E., M.M. Mocanu, and D.M. Yellon. 1994. Protein kinase C: its role in ischemic preconditioning in the rat. Circ. Res. 75:586-590.
    • (1994) Circ. Res. , vol.75 , pp. 586-590
    • Speechly-Dick, M.E.1    Mocanu, M.M.2    Yellon, D.M.3
  • 22
    • 85047675886 scopus 로고
    • Preconditioning of isolated rabbit cardiomyocytes: Effects of glycolytic blockade, phorhol esters, and ischaemia
    • Armstrong, S., and C.E. Ganote. 1994. Preconditioning of isolated rabbit cardiomyocytes: effects of glycolytic blockade, phorhol esters, and ischaemia. Cardiovasc. Res. 28:1700-1706.
    • (1994) Cardiovasc. Res. , vol.28 , pp. 1700-1706
    • Armstrong, S.1    Ganote, C.E.2
  • 23
    • 0028169355 scopus 로고
    • 1 adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C
    • 1 adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C. Circ. Res. 75:576-584.
    • (1994) Circ. Res. , vol.75 , pp. 576-584
    • Tsuchida, A.1    Liu, Y.2    Liu, G.S.3    Cohen, M.V.4    Downey, J.M.5
  • 25
    • 0028801620 scopus 로고
    • Does protein kinase C play a role in ischemic preconditioning in rat hearts?
    • Li, Y., and R.A. Kloner. 1995. Does protein kinase C play a role in ischemic preconditioning in rat hearts? Am. J. Physiol. 268:H426-H431.
    • (1995) Am. J. Physiol. , vol.268
    • Li, Y.1    Kloner, R.A.2
  • 26
    • 0028808229 scopus 로고
    • + channel? Studies of contractile function after simulated ischemia in an atrial in vitro model
    • + channel? Studies of contractile function after simulated ischemia in an atrial in vitro model. Circ. Res. 77:1030-1035.
    • (1995) Circ. Res. , vol.77 , pp. 1030-1035
    • Speechly-Dick, M.E.1    Grover, G.J.2    Yellon, D.M.3
  • 27
    • 0029053783 scopus 로고
    • 1 receptor activation is abolished by protein kinase C inhibitors in the rabbit
    • 1 receptor activation is abolished by protein kinase C inhibitors in the rabbit. Cardiovasc. Res. 29:682-688.
    • (1995) Cardiovasc. Res. , vol.29 , pp. 682-688
    • Sakamoto, J.1    Miura, T.2    Goto, M.3    Iimura, O.4
  • 28
    • 0029130667 scopus 로고
    • Role of bradykinin in protection of ischemic preconditioning in rabbit hearts
    • Goto, M., Y. Liu, X.M. Yang, J.L. Ardell, M.V. Cohen, and J.M. Downey. 1995. Role of bradykinin in protection of ischemic preconditioning in rabbit hearts. Circ. Res. 77:611-621.
    • (1995) Circ. Res. , vol.77 , pp. 611-621
    • Goto, M.1    Liu, Y.2    Yang, X.M.3    Ardell, J.L.4    Cohen, M.V.5    Downey, J.M.6
  • 29
    • 0028914411 scopus 로고
    • Pretreatment with angiotensin II activates protein kinase C and limits myocardial infarction in isolated rabbit hearts
    • Liu, Y., A. Tsuchida, M.V. Cohen, and J.M. Downey. 1995. Pretreatment with angiotensin II activates protein kinase C and limits myocardial infarction in isolated rabbit hearts. J. Mol. Cell Cardiol. 27:883-892.
    • (1995) J. Mol. Cell Cardiol. , vol.27 , pp. 883-892
    • Liu, Y.1    Tsuchida, A.2    Cohen, M.V.3    Downey, J.M.4
  • 31
    • 0030033229 scopus 로고    scopus 로고
    • Role of activation of protein kinase C in the infarct size-limiting effect of ischemie preconditioning through activation of ecto-5′-nucleotidase
    • Kitakaze, M., K. Node, T. Minamino, K. Komamura, H. Funaya, Y. Shinozaki, M. Chujo, H. Mori, U. Inoue, M. Hori, and T. Kamada. 1996. Role of activation of protein kinase C in the infarct size-limiting effect of ischemie preconditioning through activation of ecto-5′-nucleotidase. Circulation. 93:781-791.
    • (1996) Circulation , vol.93 , pp. 781-791
    • Kitakaze, M.1    Node, K.2    Minamino, T.3    Komamura, K.4    Funaya, H.5    Shinozaki, Y.6    Chujo, M.7    Mori, H.8    Inoue, U.9    Hori, M.10    Kamada, T.11
  • 32
    • 85047680361 scopus 로고    scopus 로고
    • Preconditioning of isolated rabbit cardiomyocytes: Induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor
    • Armstrong, S.C., and C.E. Ganote. 1996. Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor. Cardiovasc. Res. 28:72-77.
    • (1996) Cardiovasc. Res. , vol.28 , pp. 72-77
    • Armstrong, S.C.1    Ganote, C.E.2
  • 35
    • 0029087178 scopus 로고
    • Does ischemic preconditioning trigger translocation of protein kinase C in the canine model?
    • Przyklenk, K., M.A. Sussman, B.Z. Simkhovich, and R.A. Kloner. 1995. Does ischemic preconditioning trigger translocation of protein kinase C in the canine model? Circulation. 92:1546-1557.
    • (1995) Circulation , vol.92 , pp. 1546-1557
    • Przyklenk, K.1    Sussman, M.A.2    Simkhovich, B.Z.3    Kloner, R.A.4
  • 36
    • 0029848823 scopus 로고    scopus 로고
    • No prevention of ischemic preconditioning by the protein kinase C inhibitor staurosporine in swine
    • Vahlhaus, C., R. Schulz, H. Post, R. Onallah, and G. Heusch. 1996. No prevention of ischemic preconditioning by the protein kinase C inhibitor staurosporine in swine. Circ. Res. 79:407-414.
    • (1996) Circ. Res. , vol.79 , pp. 407-414
    • Vahlhaus, C.1    Schulz, R.2    Post, H.3    Onallah, R.4    Heusch, G.5
  • 37
    • 0001494657 scopus 로고
    • Protein kinase C inhibitors reduce infarct size in pig hearts in vivo
    • Abstr.
    • Vogt, A., M. Barancik, D. Weihrauch, M. Arras, T. Podzuweit, and W. Schaper. 1994. Protein kinase C inhibitors reduce infarct size in pig hearts in vivo. Circulation. 90(Suppl. I):I-647. (Abstr.)
    • (1994) Circulation , vol.90 , Issue.1 SUPPL.
    • Vogt, A.1    Barancik, M.2    Weihrauch, D.3    Arras, M.4    Podzuweit, T.5    Schaper, W.6
  • 38
    • 0030472809 scopus 로고    scopus 로고
    • Direct evidence that ischemic preconditioning does not cause PKC translocalion in rabbit heart
    • Simkhovich, B.Z., K. Przyklenk, S.L. Hale, M. Patterson, and R.A. Kloner. 1996. Direct evidence that ischemic preconditioning does not cause PKC translocalion in rabbit heart. Cardiovasc. Res. 32:1064-1070.
    • (1996) Cardiovasc. Res. , vol.32 , pp. 1064-1070
    • Simkhovich, B.Z.1    Przyklenk, K.2    Hale, S.L.3    Patterson, M.4    Kloner, R.A.5
  • 39
    • 0027224020 scopus 로고
    • Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs
    • Li, X.Y., P.B. McCay, M. Zughaib, M.O. Jeroudi, J.F. Triana, and R. Bolli. 1993. Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs. J. Clin. Invest. 92:1025-1041.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1025-1041
    • Li, X.Y.1    McCay, P.B.2    Zughaib, M.3    Jeroudi, M.O.4    Triana, J.F.5    Bolli, R.6
  • 40
    • 0025954008 scopus 로고
    • Postischemic myocardial "stunning": Identification of major differences between the open-chest and the conscious dog and evaluation of the oxygen radical hypothesis in the conscious dog
    • Triana, J.F., X. Y. Li, U. Jamaluddin, J.I. Thornby, and R. Bolli. 1991. Postischemic myocardial "stunning": identification of major differences between the open-chest and the conscious dog and evaluation of the oxygen radical hypothesis in the conscious dog. Circ. Res. 69:731-747.
    • (1991) Circ. Res. , vol.69 , pp. 731-747
    • Triana, J.F.1    Li, X.Y.2    Jamaluddin, U.3    Thornby, J.I.4    Bolli, R.5
  • 41
    • 0028219202 scopus 로고
    • Conscious rabbits become tolerant to multiple episodes of ischemic preconditioning
    • Cohen, M.V., X.M. Yang, and J.M. Downey. 1994. Conscious rabbits become tolerant to multiple episodes of ischemic preconditioning. Circ. Res. 74: 998-1004.
    • (1994) Circ. Res. , vol.74 , pp. 998-1004
    • Cohen, M.V.1    Yang, X.M.2    Downey, J.M.3
  • 42
    • 0029035342 scopus 로고
    • Acadesine extends the window of protection afforded by ischemic preconditioning in conscious rabbits
    • Burckhartt, B., X.M. Yang, A. Tsuchida, K.M. Mullane, J.M. Downey, and M.V. Cohen. 1995. Acadesine extends the window of protection afforded by ischemic preconditioning in conscious rabbits. Cardiovasc. Res. 29:653-657.
    • (1995) Cardiovasc. Res. , vol.29 , pp. 653-657
    • Burckhartt, B.1    Yang, X.M.2    Tsuchida, A.3    Mullane, K.M.4    Downey, J.M.5    Cohen, M.V.6
  • 44
    • 0030914587 scopus 로고    scopus 로고
    • Premedication with the opioid analgesic butorphanol raises the threshold for ischemic preconditioning in dogs
    • Schwartz, L.M., R.B. Jennings, and K.A. Reimer. 1997. Premedication with the opioid analgesic butorphanol raises the threshold for ischemic preconditioning in dogs. Basic Res. Cardiol. 92:106-114.
    • (1997) Basic Res. Cardiol. , vol.92 , pp. 106-114
    • Schwartz, L.M.1    Jennings, R.B.2    Reimer, K.A.3
  • 45
    • 0028811653 scopus 로고
    • Protein kinase C: Structure, function, and regulation
    • Newton, A.C. 1995. Protein kinase C: structure, function, and regulation. Biochem. J. 270:28495-28498.
    • (1995) Biochem. J. , vol.270 , pp. 28495-28498
    • Newton, A.C.1
  • 47
    • 0024320079 scopus 로고
    • Molecular genetic analysis of the regulatory and catalytic domains of protein kinase C
    • Kaibuchi, K., Y. Fukumoto, N. Oku, Y. Takai, K. Arai, and M. Muramatsu. 1989. Molecular genetic analysis of the regulatory and catalytic domains of protein kinase C. J. Biol. Chem. 264:13489-13496.
    • (1989) J. Biol. Chem. , vol.264 , pp. 13489-13496
    • Kaibuchi, K.1    Fukumoto, Y.2    Oku, N.3    Takai, Y.4    Arai, K.5    Muramatsu, M.6
  • 48
    • 0030199062 scopus 로고    scopus 로고
    • Translocation of PKC, protein phosphatase inhibition and preconditioning of rabbit cardiomyocytes
    • Armstrong, S.C., D.B. Hoover, M.H. Delacey, and C.E. Ganote. 1996. Translocation of PKC, protein phosphatase inhibition and preconditioning of rabbit cardiomyocytes. J. Mol. Cell Cardiol. 28:1479-1492.
    • (1996) J. Mol. Cell Cardiol. , vol.28 , pp. 1479-1492
    • Armstrong, S.C.1    Hoover, D.B.2    Delacey, M.H.3    Ganote, C.E.4
  • 49
    • 0031105023 scopus 로고    scopus 로고
    • Protection of ischemic preconditioning is dependent upon a critical timing sequence of protein kinase C activation
    • Yang, X.M., H. Sato, J.M. Downey, and M.V. Cohen. 1997. Protection of ischemic preconditioning is dependent upon a critical timing sequence of protein kinase C activation. J. Mol. Cell Cardiol. 29:991-999.
    • (1997) J. Mol. Cell Cardiol. , vol.29 , pp. 991-999
    • Yang, X.M.1    Sato, H.2    Downey, J.M.3    Cohen, M.V.4
  • 50
    • 0029804133 scopus 로고    scopus 로고
    • Myocardial adaptation, stress proteins, and the second window of protection
    • Marber, M.S., and D.M. Yellon. 1996. Myocardial adaptation, stress proteins, and the second window of protection. Ann. NY Acad. Sci. 793:123-141.
    • (1996) Ann. NY Acad. Sci. , vol.793 , pp. 123-141
    • Marber, M.S.1    Yellon, D.M.2


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