The α1-adrenoceptor subtype- and protein kinase C isoform-dependence of norepinephrine's actions in cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 7, 2000, Pages 1193-1209

  Rohde, Shira ^a   Sabri, Abdelkarim ^a   Kamasamudran, Ragunathan ^a   Steinberg, Susan F ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cardiomyocytes; Hypertrophy; Mitogen activated protein kinase; Protein kinase C; 1 Adrenergic receptor subtypes

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; PROTEIN KINASE C; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME REGULATION; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; LIGAND BINDING; MULTIGENE FAMILY; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION;

ANIMALIA;

EID: 0033844365     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1153     Document Type: Article

References (49)

1. 1-Adrenergic receptor subtypes: Molecular structure, function and signaling
2. Localization of protein kinase C isozymes in cardiac myocytes
3. Differential regulation of protein kinase C isoforms in isolated neonatal and adult cardiomyocytes
4. Protein kinase C isoform expression and regulation in the developing rat heart
5. PKC-λ is the atypical protein kinase C isoform expressed by immature ventricle
6. Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts
7. 1-adrenergic receptors: Consensus update
8. A-61603. A potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype
9. 1-adrenoceptors
10. Cloning of the rat α(1C)-adrenergic receptor from cardiac myocytes; α(1C), α(a1B), and α(1D) mRNAs are present in cardiac myocytes but not in cardiac fibroblasts
11. 1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo; Repression of α(1B) and α(1D) but induction of α(1C)
12. 1-adrenoceptor subtypes to phospholipase C and mitigen activated protein kinase in neonatal rat cardiac myocytes
13. 1-adrenergic receptor subtypes modulate catecholamine induced increases and decreases in ventricular automaticity
14. The α(1A)-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy
15. 1-adrenergic agonists in adult rat hearts
16. 1-adrenoceptors in the rabbit ventricular myocardium
17. Regulation of phospholipase C and D in rat ventricular myocytes: Stimulation by endothelin-1, bradykinin, and phenylephrine
18. Myocardial expression of a constitutively active α(1B)-adrenergic receptor in transgenic mice induces cardiac hypertrophy
19. 1-adrenergic receptor-mediated regulation of β-adrenergic signaling
20. 1 adrenergic response
21. A new member of the third class in the protein kinase C family, PKCλ, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells
22. Differential translocation of protein kinase C isozymes by thrombin and platelet-derived growth factor
23. Isolation and characterization of the ε subspecies of protein kinase C from rat brain
24. Endothelin-dependent actions in cultured AT-1 cardiac myocytes; The role of the ε-isoform of protein kinase C
25. 1-and β-adrenoceptors
26. Phenylephrine and endothelin differentially stimulate cardiac PI hydrolysis and ANF expression
27. Expression of protein kinase C isoforms during cardiac ventricular development
28. 1 cells
29. Evidence of increased synthesis as well as increased degradation of protein kinase C after treatment of human osteosarcoma cells with phorbol ester
30. Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes
31. Distinct pathways of G(i)- and G(q)-mediated mitogen-activated protein kinase activation
32. Thrombin receptor actions in neonatal rat ventricular myocytes
33. 1-adrenergic chronotropic response in neuropeptide Y-treated cardiomyocytes
34. A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression
35. Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy
36. 1-adrenoceptors: An overview
37. 1-adrenergic receptor subtype mRNAs
38. Thyroid hormone represses protein kinase C isoform expression and activity in rat cardiac myocytes
39. Ischemic preconditioning induces selective translocation of protein kinase C isoforms epsilon and eta in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity
40. Hypoxia alters the subcellular distribution of protein kinase C isoforms in neonatal rat ventricular myocytes
41. Constitutively active mutants of the α(1a)- and α(1b)-adrenergic receptor subtypes reveal coupling to different signaling pathways and physiological responses in rat cardiac myocytes
42. 1-adrenergic receptor subtypes in human tissues: Implications for human α-adrenergic physiology
43. The specific contribution of the novel alpha-1D adrenoceptor to the contraction of vascular smooth muscle
44. Phosphorylation specificities of protein kinase C isozymes for bovine cardiac troponin I and troponin T and sites within these proteins and regulation of myofilament properties
45. A protein kinase C translocation inhibitor as an isozyme-specific antagonist of cardiac function
46. The structure, expression, and properties of additional members of the protein kinase C family
47. The common structure and activities of four subspecies of rat brain protein kinase C family
48. Sequence of human protein kinase C-α
49. Sequence and expression of human protein kinase C-ε