Ischemic preconditioning translocates PKC-δ and-ε, which mediate functional protection in isolated rat heart

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 275, Issue 6 44-6, 1998, Pages

  Kawamura, Shuji ^a   Yoshida, Ken Ichi ^a   Miura, Toshiro ^a   Mizukami, Yoichi ^a   Matsuzaki, Masunori ^a,b  

^a YAMAGUCHI UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Contractile function; Ischemia; Low calcium perfusion; Protein kinase C inhibitors; Protein kinase C isoforms

Indexed keywords

BISINDOLYLMALEIMIDE; ISOENZYME; PROTEIN KINASE C;

ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 33750865610     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1998.275.6.h2266     Document Type: Article

References (36)

1. 1-adrenergic mechanism. Circ. Res. 73: 656-670, 1993.
2. Clement, O., M. Puceat, M. P. Walsh, and G. Vassort. Protein kinase C enhances myosin light-chain kinase effects on force development and ATPase activity in rat single skinned cardiac cells. Biochem. J. 285: 311-317, 1992.
3. Gottlieb, R. A., D. L. Gruol, J. Y. Zhu, and R. L. Engler. Preconditioning in rabbit cardiomyocytes: role of pH, vacuolar proton ATPase, and apoptosis. J. Clin. Invest. 97: 2391-2398, 1996.
4. Gray, M. O., J. S. Karliner, and D. Mochly-Rosen. A selective epsilon-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death. J. Biol. Chem. 272: 30945-30951, 1997.
5. 1-receptors. Circulation 86: 1310-1316, 1992.
6. Herbert, J. M., J. M. Augereau, J. Gleye, and J. P. Maffrand. Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 172: 993-999, 1990.
7. 1β-adrenoceptors, pertussis toxin-sensitive G proteins, and protein kinase C. Circulation 92: 2259-2265, 1995.
8. Kitakaze, M., K. Node, T. Minamino, K. Komamura, H. Funaya, Y. Shinozaki, M. Chujo, H. Mori, M. Inoue, M. Hori, and T. Kamada. Role of activation of protein kinase C in the infarct size-limiting effect of ischemic preconditioning through activation of ecto-5′-nucleotidase. Circulation 93: 781-791, 1996.
9. Ko, F. N., I. S. Chen, S. J. Wu, L. G. Lee, T. F. Haung, and C. M. Teng. Antiplatelet effects of chelerythrine chloride isolated from Zanthoxylum simulans. Biochim. Biophys. Acta 1052: 360-365, 1990.
10. 6-(2-phenylisopropyl)-adenosine on myocardial inositol phosphate content and force of contraction. Br. J. Pharmacol. 101: 829-834, 1990.
11. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
12. + channels: a possible mechanistic link to ischemic preconditioning. Circ. Res. 79: 399-406, 1996.
13. 1 adenosine receptors in rabbit heart. Circulation 84: 350-356, 1991.
14. + currents by protein kinase C and adenosine. Circ. Res. 78: 443-454, 1996.
15. Liu, Y., K. Ytrehus, and J. M. Downey. Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium. J. Mol. Cell. Cardiol. 26: 661-668, 1994.
16. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
17. Mitchell, M. B., X. Meng, L. Ao, J. M. Brown, A. H. Harken, and A. Banerjee. Preconditioning of isolated rat heart is mediated by protein kinase C. Circ. Res. 76: 73-81, 1995.
18. Miyawaki, H., X. Zhou, and M. Ashraf. Calcium preconditioning elicits strong protection against ischemic injury via protein kinase C signaling pathway. Circ. Res. 79: 137-146, 1996.
19. Mizukami, Y., T. Hirata, and K. Yoshida. Nuclear translocation of PKC during ischemia and its inhibition by wortmannin, an inhibitor of phosphatidylinositol 3-kinase. FEBS Lett. 401: 247-251, 1997.
20. Murry, C. E., R. B. Jennings, and K. A. Reimer. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circ. Res. 74: 1124-1136, 1986.
21. Newton, A. C. Protein kinase C: structure, function and regulation. J. Biol. Chem. 270: 28495-28498, 1995.
22. Nishizuka, Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258: 607-614, 1992.
23. Ping, P., J. Zhang, Y. Qiu, X.-L. Tang, S. Manchikalapudi, X. Cao, and R. Bolli. Ischemic preconditioning induces selective translocation of protein kinase C isoforms ε and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity. Circ. Res. 81: 404-414, 1997.
24. Rybin, V. O., P. M. Buttrick, and S. F. Steinberg. PKC-λ is the atypical protein kinase C isoform expressed by immature ventricle. Am. J. Physiol. 272 (Heart Circ. Physiol. 41): H1636-H1642, 1997.
25. Sadoshima, J., and S. Izumo. Signal transduction pathways of angiotensin II-induced c-fos gene expression in cardiac myocytes in vitro: roles of phospholipid-derived second messengers. Circ. Res. 73: 424-438, 1993.
26. Schott, R. J., E. R. Rohman, E. R. Braun, and W. Schaper. Ischemic preconditioning reduces infarct size in swine myocardium. Circ. Res. 66: 1133-1142, 1990.
27. + channel? Studies of contractile function after simulated ischemia in an atrial in vivo model. Circ. Res. 77: 1030-1035, 1995.
28. Speechly-Dick, M. E., M. M. Mocanu, and D. M. Yellon. Protein kinase C: its role in ischemic preconditioning in the rat. Circ. Res. 75: 586-590, 1994.
29. Toullec, D., P. Pianetti, H. Coste, P. Bellevergue, T. Grand-Perret, M. Ajakane, V. Baudet, E. Boursier, F. Loriolle, L. Duhamel, D. Charon, and J. Kirilovsky. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266: 15771-15781, 1991.
30. Towbin, H., T. Staehelin, and J. Gordon. Electrophoretic transfer of proteins from polyacrylarnide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76: 4350-4354, 1979.
31. 1-adrenergic stimulated phosphatidylinositol cycle in cultured rat cardiomyocytes. J. Mol. Cell. Cardiol. 26: 1081-1093, 1994.
32. Venema, R. C., R. L. Raynor, T. A. Noland, and J. F. Kuo. Role of protein kinase C in the phosphorylation of cardiac myosin light chain 2. Biochem. J. 294: 401-406, 1993.
33. Webster, K. A., D. J. Discher, and N. H. Bishopric. Cardioprotection in an in vitro model of hypoxic preconditioning. J. Mol. Cell. Cardiol. 27: 453-458, 1995.
34. Wilkinson, S. E., P. J. Parker, and J. S. Nixon. Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem. J. 294: 335-337, 1993.
35. Yoshida, K., M. Inui, K. Harada, T. C. Saido, Y. Sorimachi, T. Ishihara, S. Kawashima, and K. Sobue. Reperfusion of rat heart after brief ischemia induces proteolysis of calspectin (nonerythroid spectrin or fodrin) by calpain. Circ. Res. 77: 603-610, 1995.
36. Ytrehus, K., Y. Liu, and J. M. Downey. Preconditioning protects ischemic rabbit heart by protein kinase C activation. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H1145-H1152, 1994.