Exercise directly enhances myocardial tolerance to ischaemia-reperfusion injury in the rat through a protein kinase C mediated mechanism

Heart

Volumn 85, Issue 3, 2001, Pages 331-336

  Yamashita, N ^a   Baxter, G F ^a   Yellon, D M ^a  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

Author keywords

Cardioprotection; Exercise; Myocardial infarction; Protein kinase C

Indexed keywords

CHELERYTHRINE; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TREADMILL EXERCISE;

EID: 0034768328     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/heart.85.3.331     Document Type: Article

References (31)

1. Exercise standards. A statement for healthcare professionals from the American Heart Association
2. Statement on exercise. Benefits and recommendations for physical activity programs for all Americans. A statement for health professionals by the Committee on Exercise and Cardiac Rehabilitation of the Council on Clinical Cardiology, American Heart Association
3. Physical inactivity as a risk factor for coronary heart disease: A WHO and International Society and Federation of Cardiology position statement
4. Response of plasma norepinephrine to dynamic exercise in patients with congestive heart failure
5. Release of endogenous catecholamines in the ischemic myocardium of the rat
6. Exercise training improves cardiac function following ischemia in the isolated, working rat heart
7. Exercise training improves metabolic response after ischemia in isolated working rat heart
8. Enhanced postischemic myocardial recovery following exercise induction of HSP 72
9. Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation
10. Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia
11. Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction
12. Adenosine receptor involvement in a delayed phase of protection 24 hours following ischemic preconditioning
13. Involvement of protein kinase C in the delayed cytoprotection following sublethal ischaemia in rabbit myocardium
14. Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that ε is the isoform involved
15. Heat-shock response is associated with enhanced postischemic ventricular recovery
16. Heat-shock protein induction in rat hearts: A direct correlation between the amount of heat-shock protein induced and the degree of myocardial protection
17. Protein kinase C is involved in resistance to myocardial infarction induced by heat stress
18. Whole-body hyperthermia provides biphasic cardioprotection against ischemia/reperfusion injury in the rat
19. Ischemic preconditioning induces selective translocation of protein kinase C isoforms ε and η in the hearts of conscious rabbits without subcellular redistribution of total protein kinase C activity
20. Early phase acute myocardial infarct size quantification: Validation of the triphenyltetrazolium chloride tissue enzyme staining technique
21. Exercise, training, and neutrophil function
22. Species variation in the coronary collateral circulation during regional myocardial ischaemia: A critical determinant of the rate of evolution and extent of myocardial infarction
23. Effect of physical training on coronary collateral circulation of the rat
24. Delayed coronary endothelial protection 24 hours after preconditioning. Role of free radicals
25. Endothelium-mediated control of coronary vascular tone after chronic exercise training
26. Attenuation of myocardial ischaemic injury 24 h after diacylglycerol treatment in vivo
27. Chelerythrine is a potent and specific inhibitor of protein kinase C
28. A selective ε-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death
29. Opioid-induced second window of cardioprotection: Potential role of mitochondrial KATP channels
30. Adrenergic induction of bimodal myocardial protection: Signal transduction and cardiac gene reprogramming