In vivo phosphorylation of cardiac troponin I by protein kinase Cβ2 decreases cardiomyocyte calcium responsiveness and contractility in transgenic mouse hearts

Journal of Clinical Investigation

Volumn 102, Issue 1, 1998, Pages 72-78

  Takeishi, Yasuchika ^a   Chu, Guoxiang ^a   Kirkpatrick, Darryl M ^a   Li, Zhenling ^b   Wakasaki, Hisao ^b   Kranias, Evangelia G ^a   King, George L ^b   Walsh, Richard A ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Heart failure; Hypertrophy; Protein kinase; Signal transduction; Transgenic animal

Indexed keywords

PROTEIN KINASE C; TROPONIN I;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HEART FAILURE; HEART FUNCTION; HEART HYPERTROPHY; HEART MUSCLE CELL; IN VIVO STUDY; ISOLATED HEART; MOUSE; MUSCLE CONTRACTILITY; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

EID: 0032128254     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI2709     Document Type: Article

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