Modulation of intestinal tight junctions by zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model

Journal of Clinical Investigation

Volumn 99, Issue 6, 1997, Pages 1158-1164

  Fasano, Alessio ^a   Uzzau, Sergio ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

diabetes; drugs; immunodeficiency; oral delivery; permeability

Indexed keywords

CHOLERA TOXIN; GLUCOSE; HUMAN INSULIN; IMMUNOGLOBULIN G;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; GLUCOSE BLOOD LEVEL; ILEUM; INTESTINE MUCOSA PERMEABILITY; JEJUNUM; MACROMOLECULE; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RABBIT; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TIGHT JUNCTION;

EID: 0030938926     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119271     Document Type: Article

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