-
1
-
-
0030005037
-
Mutant ras epitopes as targets for cancer vaccines
-
Abrams, S. I., P. H. Hand, K. Y. Tsang, and J. Schlom. 1996. Mutant ras epitopes as targets for cancer vaccines. Semin. Oncol. 23:118-134.
-
(1996)
Semin. Oncol.
, vol.23
, pp. 118-134
-
-
Abrams, S.I.1
Hand, P.H.2
Tsang, K.Y.3
Schlom, J.4
-
2
-
-
0030613532
-
Nuclear factor-κB/Rel blocks transforming growth factor β1-induced apoptosis of murine hepatocyte cell lines
-
Arsura, M., M. J. FitzGerald, N. Fausto, and G. E. Sonenshein. 1997. Nuclear factor-κB/Rel blocks transforming growth factor β1-induced apoptosis of murine hepatocyte cell lines. Cell Growth Differ. 8:1049-1059.
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 1049-1059
-
-
Arsura, M.1
FitzGerald, M.J.2
Fausto, N.3
Sonenshein, G.E.4
-
3
-
-
0033623830
-
Role of the IκB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells
-
Arsura, M., F. Mercurio, A. L. Oliver, S. S. Thorgeirsson, and G. E. Sonenshein. 2000. Role of the IκB kinase complex in oncogenic Ras- and Rafmediated transformation of rat liver epithelial cells. Mol. Cell. Biol. 20:5381-5391.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5381-5391
-
-
Arsura, M.1
Mercurio, F.2
Oliver, A.L.3
Thorgeirsson, S.S.4
Sonenshein, G.E.5
-
4
-
-
0028174061
-
Function and activation of NF-κB in the immune system
-
Baeuerle, P. A., and T. Henkel. 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12:141-179.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
5
-
-
0026527184
-
The 65-kDa subunit of human NF-κB functions as a potent transcriptional activator and a target for v-Rel-mediated repression
-
Ballard, D. W., E. P. Dixon, N. J. Peffer, H. Bogerd, S. Doerre, B. Stein, and W. C. Greene. 1992. The 65-kDa subunit of human NF-κB functions as a potent transcriptional activator and a target for v-Rel-mediated repression. Proc. Natl. Acad. Sci. USA 89:1875-1879.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 1875-1879
-
-
Ballard, D.W.1
Dixon, E.P.2
Peffer, N.J.3
Bogerd, H.4
Doerre, S.5
Stein, B.6
Greene, W.C.7
-
6
-
-
18844465632
-
Constitutive nuclear factor-κB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells
-
Bargou, R. C., F. Emmerich, D. Krappmann, K. Bommert, M. Y. Mapara, W. Arnold, H. D. Royer, E. Grinstein, A. Greiner, C. Scheidereit, and B. Dorken. 1997. Constitutive nuclear factor-κB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. J. Clin. Investig. 100:2961-2969.
-
(1997)
J. Clin. Investig.
, vol.100
, pp. 2961-2969
-
-
Bargou, R.C.1
Emmerich, F.2
Krappmann, D.3
Bommert, K.4
Mapara, M.Y.5
Arnold, W.6
Royer, H.D.7
Grinstein, E.8
Greiner, A.9
Scheidereit, C.10
Dorken, B.11
-
7
-
-
0024376173
-
ras oncogenes in human cancer: A review
-
Bos, J. L. 1989. ras oncogenes in human cancer: a review. Cancer Res. 49:4682-4689.
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
8
-
-
0028986075
-
Control of IκBα proteolysis by site-specific, signal-induced phosphorylation
-
Brown, K., S. Gerstberger, L. Carlson, G. Franzoso, and U. Siebenlist. 1995. Control of IκBα proteolysis by site-specific, signal-induced phosphorylation. Science 267:1485-1488.
-
(1995)
Science
, vol.267
, pp. 1485-1488
-
-
Brown, K.1
Gerstberger, S.2
Carlson, L.3
Franzoso, G.4
Siebenlist, U.5
-
9
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering, B. M., and P. J. Coffer. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
10
-
-
0028823816
-
Increased expression of lysyl oxidase in skin with scleroderma
-
Chanoki, M., M. Ishii, H. Kobayashi, H. Fushida, N. Yashiro, T. Hamada, and A. Ooshima. 1995. Increased expression of lysyl oxidase in skin with scleroderma. Br. J. Dermatol. 133:710-715.
-
(1995)
Br. J. Dermatol.
, vol.133
, pp. 710-715
-
-
Chanoki, M.1
Ishii, M.2
Kobayashi, H.3
Fushida, H.4
Yashiro, N.5
Hamada, T.6
Ooshima, A.7
-
11
-
-
0030004897
-
Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity
-
Chen, Z. J., L. Parent, and T. Maniatis. 1996. Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity. Cell 84:853-862.
-
(1996)
Cell
, vol.84
, pp. 853-862
-
-
Chen, Z.J.1
Parent, L.2
Maniatis, T.3
-
12
-
-
0025073054
-
Expression of gene rrg is associated with reversion of NIH 3T3 transformed by LTR-c-H-ras
-
Contente, S., K. Kenyon, D. Rimoldi, and R. M. Friedman. 1990, Expression of gene rrg is associated with reversion of NIH 3T3 transformed by LTR-c-H-ras. Science 249:796-798.
-
(1990)
Science
, vol.249
, pp. 796-798
-
-
Contente, S.1
Kenyon, K.2
Rimoldi, D.3
Friedman, R.M.4
-
13
-
-
0032984911
-
Epigenetic inhibition of lysyl oxidase transcription after transformation by ras oncogene
-
Contente, S., K. Kenyon, P. Sriraman, S. Subramanyan, and R. M. Friedman. 1999. Epigenetic inhibition of lysyl oxidase transcription after transformation by ras oncogene. Mol. Cell. Biochem, 194:79-91.
-
(1999)
Mol. Cell. Biochem.
, vol.194
, pp. 79-91
-
-
Contente, S.1
Kenyon, K.2
Sriraman, P.3
Subramanyan, S.4
Friedman, R.M.5
-
14
-
-
0037050723
-
Somatic mutations of the lysyl oxidase gene on chromosome 5q23.1 in colorectal tumors
-
Csiszar, K., S. F. Fong, A. Ujfalusi, S. A. Krawetz, E. P. Salvati, J. W. Mackenzie, and C. D. Boyd. 2002. Somatic mutations of the lysyl oxidase gene on chromosome 5q23.1 in colorectal tumors. Int. J. Cancer 97:636-642.
-
(2002)
Int. J. Cancer
, vol.97
, pp. 636-642
-
-
Csiszar, K.1
Fong, S.F.2
Ujfalusi, A.3
Krawetz, S.A.4
Salvati, E.P.5
Mackenzie, J.W.6
Boyd, C.D.7
-
15
-
-
0031434174
-
Micro-injection of recombinant lysyl oxidase blocks oncogenic p21-Ha-Ras and progesterone effects on Xenopus laevis oocyte maturation
-
Di Donato, A., J. C. Lacal, M. Di Duca, M. Giampuzzi, G. Ghiggeri, and R. Gusmano. 1997. Micro-injection of recombinant lysyl oxidase blocks oncogenic p21-Ha-Ras and progesterone effects on Xenopus laevis oocyte maturation. FEBS Lett. 419:63-68.
-
(1997)
FEBS Lett.
, vol.419
, pp. 63-68
-
-
Di Donato, A.1
Lacal, J.C.2
Di Duca, M.3
Giampuzzi, M.4
Ghiggeri, G.5
Gusmano, R.6
-
16
-
-
0029670083
-
Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation
-
Di Donato, J. A., F. Mercurio, C. Rosette, J. Wu-Li, H. Suyang, S. Ghosh, and M. Karin. 1996. Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation. Mol. Cell. Biol. 16:1295-1304.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1295-1304
-
-
Di Donato, J.A.1
Mercurio, F.2
Rosette, C.3
Wu-Li, J.4
Suyang, H.5
Ghosh, S.6
Karin, M.7
-
17
-
-
0030610362
-
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
-
Di Donato, J. A., M. Hayakawa, D. M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388:548-554.
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
Di Donato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
18
-
-
0032053709
-
Mechanisms and consequences of activation of protein kinase B/Akt
-
Downward, J. 1998. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10:262-267.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 262-267
-
-
Downward, J.1
-
19
-
-
0033565217
-
Expression of a dominant-negative mutant inhibitor-κBα of nuclear factor-κB in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo
-
Duffey, D. C., Z. Chen, G. Dong, F. G. Ondrey, J. S. Wolf, K. Brown, U. Siebenlist, and C. Van Waes. 1999. Expression of a dominant-negative mutant inhibitor-κBα of nuclear factor-κB in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo. Cancer Res. 59:3468-3474.
-
(1999)
Cancer Res.
, vol.59
, pp. 3468-3474
-
-
Duffey, D.C.1
Chen, Z.2
Dong, G.3
Ondrey, F.G.4
Wolf, J.S.5
Brown, K.6
Siebenlist, U.7
Van Waes, C.8
-
20
-
-
0025302552
-
Interaction of an NF-κB-like factor with a site upstream of the c-myc promoter
-
Duyao, M. P., A. J. Buckler, and G. E. Sonenshein. 1990. Interaction of an NF-κB-like factor with a site upstream of the c-myc promoter. Proc. Natl. Acad. Sci. USA 87:4727-4731.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 4727-4731
-
-
Duyao, M.P.1
Buckler, A.J.2
Sonenshein, G.E.3
-
21
-
-
0030882666
-
Oncogenic Ha-Ras-induced signaling activates NF-κB transcriptional activity, which is required for cellular transformation
-
Finco, T. S., J. K. Westwick, J. L. Norris, A. A. Beg, C. J. Der, and A. S. Baldwin, Jr. 1997. Oncogenic Ha-Ras-induced signaling activates NF-κB transcriptional activity, which is required for cellular transformation. J. Biol. Chem. 272:24113-24116.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24113-24116
-
-
Finco, T.S.1
Westwick, J.K.2
Norris, J.L.3
Beg, A.A.4
Der, C.J.5
Baldwin A.S., Jr.6
-
22
-
-
0029984529
-
The Ras-Raf pathway is activated in human immunodeficiency virus-infected monocytes and participates in the activation of NF-κB
-
Folgueira, L., A. Algeciras, W. S. MacMorran, G. D. Bren, and C. V. Paya. 1996. The Ras-Raf pathway is activated in human immunodeficiency virus-infected monocytes and participates in the activation of NF-κB. J. Virol. 70:2332-2338.
-
(1996)
J. Virol.
, vol.70
, pp. 2332-2338
-
-
Folgueira, L.1
Algeciras, A.2
MacMorran, W.S.3
Bren, G.D.4
Paya, C.V.5
-
23
-
-
0034680779
-
Lysyl oxidase activates the transcription activity of human collagen III promoter: Possible involvement of Ku antigen
-
Giampuzzi, M., G. Botti, M. Di Duca, L. Arata, G. Ghiggeri, R. Gusmano, R. Ravazzolo, and A. Di Donato. 2000. Lysyl oxidase activates the transcription activity of human collagen III promoter: possible involvement of Ku antigen. J. Biol. Chem. 275:36341-36349.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36341-36349
-
-
Giampuzzi, M.1
Botti, G.2
Di Duca, M.3
Arata, L.4
Ghiggeri, G.5
Gusmano, R.6
Ravazzolo, R.7
Di Donato, A.8
-
24
-
-
0035800851
-
Down-regulation of lysyl oxidase-induced tumorigenic transformation in NRK-49F cells characterized by constitutive activation of ras proto-oncogene
-
Giampuzzi, M., G. Botti, M. Cilli, R. Gusmano, A. Borel, P. Sommer, and A. Di Donato. 2001. Down-regulation of lysyl oxidase-induced tumorigenic transformation in NRK-49F cells characterized by constitutive activation of ras proto-oncogene. J. Biol. Chem. 276:29226-29232.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29226-29232
-
-
Giampuzzi, M.1
Botti, G.2
Cilli, M.3
Gusmano, R.4
Borel, A.5
Sommer, P.6
Di Donato, A.7
-
25
-
-
0029662342
-
Rel/NF-κB/IκB proteins and cancer
-
Gilmore, T. D., M. Koedood, K. A. Piffat, and D. W. White. 1996. Rel/NF-κB/IκB proteins and cancer. Oncogene 13:1367-1378.
-
(1996)
Oncogene
, vol.13
, pp. 1367-1378
-
-
Gilmore, T.D.1
Koedood, M.2
Piffat, K.A.3
White, D.W.4
-
26
-
-
0027488135
-
Up-regulation of lysyl oxidase in spontaneous revertants of H-ras-transformed rat fibroblasts
-
Hajnal, A., R. Klemenz, and R. Schafer. 1993. Up-regulation of lysyl oxidase in spontaneous revertants of H-ras-transformed rat fibroblasts. Cancer Res. 53:4670-4675.
-
(1993)
Cancer Res.
, vol.53
, pp. 4670-4675
-
-
Hajnal, A.1
Klemenz, R.2
Schafer, R.3
-
27
-
-
0029121634
-
Quantitative polymerase chain reaction of lysyl oxidase mRNA in malignantly transformed human cell lines demonstrates that their low lysyl oxidase activity is due to low quantities of its mRNA and low levels of transcription of the respective gene
-
Hamalainen, E. R., R. Kemppainen, H. Kuivaniemi, G. Tromp, A. Vaheri, T. Pihlajaniemi, and K. I. Kivirikko. 1995. Quantitative polymerase chain reaction of lysyl oxidase mRNA in malignantly transformed human cell lines demonstrates that their low lysyl oxidase activity is due to low quantities of its mRNA and low levels of transcription of the respective gene. J. Biol. Chem. 270:21590-21593.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21590-21593
-
-
Hamalainen, E.R.1
Kemppainen, R.2
Kuivaniemi, H.3
Tromp, G.4
Vaheri, A.5
Pihlajaniemi, T.6
Kivirikko, K.I.7
-
28
-
-
0034463986
-
Growth hormone prevents apoptosis through activation of nuclear factor-κB in interleukin-3-dependent Ba/F3 cell line
-
Jeay, S., G. E. Sonenshein, M. C. Postel-Vinay, and E. Baixeras. 2000. Growth hormone prevents apoptosis through activation of nuclear factor-κB in interleukin-3-dependent Ba/F3 cell line. Mol. Endocrinol. 14:650-661.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 650-661
-
-
Jeay, S.1
Sonenshein, G.E.2
Postel-Vinay, M.C.3
Baixeras, E.4
-
29
-
-
0034677549
-
NF-κB is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis
-
Jo, H., R. Zhang, H. Zhang, T. A. McKinsey, J. Shao, R. D. Beauchamp, D. W. Ballard, and P. Liang. 2000. NF-κB is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis. Oncogene 19:841-849.
-
(2000)
Oncogene
, vol.19
, pp. 841-849
-
-
Jo, H.1
Zhang, R.2
Zhang, H.3
McKinsey, T.A.4
Shao, J.5
Beauchamp, R.D.6
Ballard, D.W.7
Liang, P.8
-
30
-
-
0034795435
-
Farnesyl transferase inhibitors: A novel therapy for breast cancer
-
Johnston, S. R., and L. R. Kelland. 2001. Farnesyl transferase inhibitors: a novel therapy for breast cancer. Endocr. Relat. Cancer 8:227-235.
-
(2001)
Endocr. Relat. Cancer
, vol.8
, pp. 227-235
-
-
Johnston, S.R.1
Kelland, L.R.2
-
31
-
-
0028279412
-
Lysyl oxidase cDNA of myofibroblast from mouse fibrotic liver
-
Jourdan-Le Saux, C., C. Gleyzal, J. M. Garnier, M. Peraldi, P. Sommer, and J. A. Grimaud. 1994. Lysyl oxidase cDNA of myofibroblast from mouse fibrotic liver. Biochem. Biophys. Res. Commun. 199:587-592.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.199
, pp. 587-592
-
-
Jourdan-Le Saux, C.1
Gleyzal, C.2
Garnier, J.M.3
Peraldi, M.4
Sommer, P.5
Grimaud, J.A.6
-
32
-
-
0023039150
-
Ultrastructural immunolocalization of lysyl oxidase in vascular connective tissue
-
Kagan, H. M., C. A. Vaccaro, R. E. Bronson, S. S. Tang, and J. S. Brody. 1986. Ultrastructural immunolocalization of lysyl oxidase in vascular connective tissue. J. Cell Biol. 103:1121-1128.
-
(1986)
J. Cell Biol.
, vol.103
, pp. 1121-1128
-
-
Kagan, H.M.1
Vaccaro, C.A.2
Bronson, R.E.3
Tang, S.S.4
Brody, J.S.5
-
33
-
-
0030904561
-
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal
-
Kennedy, S. G., A. J. Wagner, S. D. Conzen, J. Jordan, A. Bellacosa, P. N. Tsichlis, and N. Hay. 1997. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev. 11:701-713.
-
(1997)
Genes Dev.
, vol.11
, pp. 701-713
-
-
Kennedy, S.G.1
Wagner, A.J.2
Conzen, S.D.3
Jordan, J.4
Bellacosa, A.5
Tsichlis, P.N.6
Hay, N.7
-
34
-
-
0026426468
-
Lysyl oxidase and rrg messenger RNA
-
Kenyon, K., S. Contente, P. C. Trackman, J. Tang, H. M. Kagan, and R. M. Friedman. 1991. Lysyl oxidase and rrg messenger RNA. Science 253:802.
-
(1991)
Science
, vol.253
, pp. 802
-
-
Kenyon, K.1
Contente, S.2
Trackman, P.C.3
Tang, J.4
Kagan, H.M.5
Friedman, R.M.6
-
35
-
-
0035918149
-
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1
-
Kim, S., K. Jee, D. Kim, H. Koh, and J. Chung. 2001. Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1. J. Biol. Chem. 276:12864-12870.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12864-12870
-
-
Kim, S.1
Jee, K.2
Kim, D.3
Koh, H.4
Chung, J.5
-
36
-
-
0028500187
-
The activation of phosphatidylinositol 3-kinase by Ras
-
Kodaki, T., R. Woscholski, B. Hallberg, P. Rodriguez-Viciana, J. Downward, and P. J. Parker. 1994. The activation of phosphatidylinositol 3-kinase by Ras. Curr. Biol. 4:798-806.
-
(1994)
Curr. Biol.
, vol.4
, pp. 798-806
-
-
Kodaki, T.1
Woscholski, R.2
Hallberg, B.3
Rodriguez-Viciana, P.4
Downward, J.5
Parker, P.J.6
-
37
-
-
0029810181
-
Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation
-
Kohn, A. D., F. Takeuchi, and R. A. Roth. 1996. Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation. J. Biol. Chem. 271:21920-21926.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21920-21926
-
-
Kohn, A.D.1
Takeuchi, F.2
Roth, R.A.3
-
38
-
-
0028264058
-
Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling
-
Kotani, K., K. Yonezawa, K. Hara, H. Ueda, Y. Kitamura, H. Sakaue, A. Ando, A. Chavanieu, B. Calas, and F. Grigorescu. 1994. Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling. EMBO J. 13:2313-2321.
-
(1994)
EMBO J.
, vol.13
, pp. 2313-2321
-
-
Kotani, K.1
Yonezawa, K.2
Hara, K.3
Ueda, H.4
Kitamura, Y.5
Sakaue, H.6
Ando, A.7
Chavanieu, A.8
Calas, B.9
Grigorescu, F.10
-
39
-
-
0026718293
-
Isolation of genes specifically expressed in flat revertant cells derived from activated ras-transformed NIH 3T3 cells by treatment with azatyrosine
-
Krzyzosiak, W. J., N. Shindo-Okada, H. Teshima, K. Nakajima, and S. Nishimura. 1992. Isolation of genes specifically expressed in flat revertant cells derived from activated ras-transformed NIH 3T3 cells by treatment with azatyrosine. Proc. Natl. Acad. Sci. USA 89:4879-4883.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4879-4883
-
-
Krzyzosiak, W.J.1
Shindo-Okada, N.2
Teshima, H.3
Nakajima, K.4
Nishimura, S.5
-
40
-
-
0023053020
-
Deficient production of lysyl oxidase in cultures of malignantly transformed human cells
-
Kuivaniemi, H., R. M. Korhonen, A. Vaheri, and K. I. Kivirikko. 1986. Deficient production of lysyl oxidase in cultures of malignantly transformed human cells. FEBS Lett. 195:261-264.
-
(1986)
FEBS Lett.
, vol.195
, pp. 261-264
-
-
Kuivaniemi, H.1
Korhonen, R.M.2
Vaheri, A.3
Kivirikko, K.I.4
-
41
-
-
0030659167
-
Localization and activity of lysyl oxidase within nuclei of fibrogenic cells
-
Li, W., K. Nellaiappan, T. Strassmaier, L. Graham, K. M. Thomas, and H. M. Kagan. 1997. Localization and activity of lysyl oxidase within nuclei of fibrogenic cells. Proc. Natl. Acad. Sci. USA 94:12817-12822.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12817-12822
-
-
Li, W.1
Nellaiappan, K.2
Strassmaier, T.3
Graham, L.4
Thomas, K.M.5
Kagan, H.M.6
-
42
-
-
0036297889
-
14-3-3 Antagonizes Ras-mediated Raf-1 recruitment to the plasma membrane to maintain signaling fidelity
-
Light, Y., H. Paterson, and R. Marais. 2002. 14-3-3 antagonizes Ras-mediated Raf-1 recruitment to the plasma membrane to maintain signaling fidelity. Mol. Cell. Biol. 22:4984-4996.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4984-4996
-
-
Light, Y.1
Paterson, H.2
Marais, R.3
-
43
-
-
0033961280
-
Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB
-
Madrid, L. V., C. Y. Wang, D. C. Guttridge, A. J. Schottelius, A. S. Baldwin, Jr., and M. W. Mayo. 2000. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB. Mol. Cell. Biol. 20:1626-1638.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1626-1638
-
-
Madrid, L.V.1
Wang, C.Y.2
Guttridge, D.C.3
Schottelius, A.J.4
Baldwin A.S., Jr.5
Mayo, M.W.6
-
44
-
-
0030612937
-
Requirement of NF-κB activation to suppress p53-independent apoptosis induced by oncogenic Ras
-
Mayo, M. W., C. Y. Wang, P. C. Cogswell, K. S. Rogers-Graham, S. W. Lowe, C. J. Der, and A. S. Baldwin, Jr. 1997. Requirement of NF-κB activation to suppress p53-independent apoptosis induced by oncogenic Ras. Science 278: 1812-1815.
-
(1997)
Science
, vol.278
, pp. 1812-1815
-
-
Mayo, M.W.1
Wang, C.Y.2
Cogswell, P.C.3
Rogers-Graham, K.S.4
Lowe, S.W.5
Der, C.J.6
Baldwin A.S., Jr.7
-
45
-
-
0024502703
-
ras GTPase activating protein: Signal transmitter and signal terminator
-
McCormick, F. 1989. ras GTPase activating protein: signal transmitter and signal terminator. Cell 56:5-8.
-
(1989)
Cell
, vol.56
, pp. 5-8
-
-
McCormick, F.1
-
46
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio, F., H. Zhu, B. W. Murray, A. Shevchenko, B. L. Bennett, J. Li, D. B. Young, M. Barbosa, M. Mann, A. Manning, and A. Rao. 1997. IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation. Science 278:860-866.
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
Li, J.6
Young, D.B.7
Barbosa, M.8
Mann, M.9
Manning, A.10
Rao, A.11
-
47
-
-
0032589935
-
IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex
-
Mercurio, F., B. W. Murray, A. Shevchenko, B. L. Bennett, D. B. Young, J. W. Li, G. Pascual, A. Motiwala, H. Zhu, M. Mann, and A. M. Manning. 1999. IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex. Mol. Cell. Biol. 19:1526-1538.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1526-1538
-
-
Mercurio, F.1
Murray, B.W.2
Shevchenko, A.3
Bennett, B.L.4
Young, D.B.5
Li, J.W.6
Pascual, G.7
Motiwala, A.8
Zhu, H.9
Mann, M.10
Manning, A.M.11
-
48
-
-
0035868950
-
An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway
-
Moniakis, J., S. Funamoto, M. Fukuzawa, J. Meisenhelder, T. Araki, T. Abe, R. Meili, T. Hunter, J. Williams, and R. A. Firtel. 2001. An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway. Genes Dev. 15:687-698.
-
(2001)
Genes Dev.
, vol.15
, pp. 687-698
-
-
Moniakis, J.1
Funamoto, S.2
Fukuzawa, M.3
Meisenhelder, J.4
Araki, T.5
Abe, T.6
Meili, R.7
Hunter, T.8
Williams, J.9
Firtel, R.A.10
-
49
-
-
0033793862
-
Fully processed lysyl oxidase catalyst translocates from the extracellular space into nuclei of aortic smooth-muscle cells
-
Nellaiappan, K., A. Risitano, G. Liu, G. Nicklas, and H. M. Kagan. 2000. Fully processed lysyl oxidase catalyst translocates from the extracellular space into nuclei of aortic smooth-muscle cells. J. Cell. Biochem. 79:576-582.
-
(2000)
J. Cell. Biochem.
, vol.79
, pp. 576-582
-
-
Nellaiappan, K.1
Risitano, A.2
Liu, G.3
Nicklas, G.4
Kagan, H.M.5
-
50
-
-
0033553466
-
Oncogenic Ras enhances NF-κB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways
-
Norris, J. L., and A. S. Baldwin, Jr. 1999. Oncogenic Ras enhances NF-κB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways. J. Biol. Chem. 274:13841-13846.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13841-13846
-
-
Norris, J.L.1
Baldwin A.S., Jr.2
-
51
-
-
0029959434
-
Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells
-
Oldham, S. M., G. J. Clark, L. M. Gangarosa, R. J. Coffey, Jr., and C. J. Der. 1996. Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells. Proc. Natl. Acad. Sci. USA 93:6924-6928.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6924-6928
-
-
Oldham, S.M.1
Clark, G.J.2
Gangarosa, L.M.3
Coffey R.J., Jr.4
Der, C.J.5
-
52
-
-
0035868342
-
Her-2/neu overexpression induces NF-κB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IκBα that can be inhibited by the tumor suppressor PTEN
-
Pianetti, S., M. Arsura, R. Romieu-Mourez, R. J. Coffey, and G. E. Sonenshein. 2001. Her-2/neu overexpression induces NF-κB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IκBα that can be inhibited by the tumor suppressor PTEN. Oncogene 20:1287-1299.
-
(2001)
Oncogene
, vol.20
, pp. 1287-1299
-
-
Pianetti, S.1
Arsura, M.2
Romieu-Mourez, R.3
Coffey, R.J.4
Sonenshein, G.E.5
-
53
-
-
0014348347
-
The cross-linking of collagen and elastin: Enzymatic conversion of lysine in peptide linkage to α-aminoadipic-delta-semialdehyde (allysine) by an extract from bone
-
Pinnell, S. R., and G. R. Martin. 1968. The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to α-aminoadipic-delta-semialdehyde (allysine) by an extract from bone. Proc. Natl. Acad. Sci. USA 61:708-716.
-
(1968)
Proc. Natl. Acad. Sci. USA
, vol.61
, pp. 708-716
-
-
Pinnell, S.R.1
Martin, G.R.2
-
54
-
-
0033596124
-
Aberrant rel/nfkb genes and activity in human cancer
-
Rayet, B., and C. Gelinas. 1999. Aberrant rel/nfkb genes and activity in human cancer. Oncogene 18:6938-6947.
-
(1999)
Oncogene
, vol.18
, pp. 6938-6947
-
-
Rayet, B.1
Gelinas, C.2
-
55
-
-
0031586174
-
Identification and characterization of an IκB kinase
-
Regnier, C. H., H. Y. Song, X. Gao, D. V. Goeddel, Z. Cao, and M. Rothe. 1997. Identification and characterization of an IκB kinase. Cell 90:373-383.
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Regnier, C.H.1
Song, H.Y.2
Gao, X.3
Goeddel, D.V.4
Cao, Z.5
Rothe, M.6
-
56
-
-
0032521198
-
Reduced lysyl oxidase messenger RNA levels in experimental and human prostate cancer
-
Ren, C., G. Yang, T. L. Timme, T. M. Wheeler, and T. C. Thompson. 1998. Reduced lysyl oxidase messenger RNA levels in experimental and human prostate cancer. Cancer Res. 58:1285-1290.
-
(1998)
Cancer Res.
, vol.58
, pp. 1285-1290
-
-
Ren, C.1
Yang, G.2
Timme, T.L.3
Wheeler, T.M.4
Thompson, T.C.5
-
57
-
-
0033256229
-
Comparative functional study of the lysyl oxidase promoter in fibroblasts, Ras-transformed fibroblasts, myofibroblasts and smooth muscle cells
-
Reynaud, C., C. Gleyzal, C. Jourdan-Le Saux, and P. Sommer. 1999. Comparative functional study of the lysyl oxidase promoter in fibroblasts, Rastransformed fibroblasts, myofibroblasts and smooth muscle cells. Cell. Mol. Biol. 45:1237-1247.
-
(1999)
Cell. Mol. Biol.
, vol.45
, pp. 1237-1247
-
-
Reynaud, C.1
Gleyzal, C.2
Jourdan-Le Saux, C.3
Sommer, P.4
-
58
-
-
0030911052
-
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
-
Rodriguez-Viciana, P., P. H. Warne, A. Khwaja, B. M. Marte, D. Pappin, P. Das, M. D. Waterfield, A. Ridley, and J. Downward. 1997. Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell 89:457-467.
-
(1997)
Cell
, vol.89
, pp. 457-467
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Khwaja, A.3
Marte, B.M.4
Pappin, D.5
Das, P.6
Waterfield, M.D.7
Ridley, A.8
Downward, J.9
-
59
-
-
0035328531
-
Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-κB in breast cancer
-
Romieu-Mourez, R., E. Landesman-Bollag, D. C. Seldin, A. M. Traish, F. Mercurio, and G. E. Sonenshein. 2001. Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-κB in breast cancer. Cancer Res. 61:3810-3818.
-
(2001)
Cancer Res.
, vol.61
, pp. 3810-3818
-
-
Romieu-Mourez, R.1
Landesman-Bollag, E.2
Seldin, D.C.3
Traish, A.M.4
Mercurio, F.5
Sonenshein, G.E.6
-
60
-
-
0032541657
-
IKKγ is an essential regulatory subunit of the IκB kinase complex
-
Rothwarf, D. M., E. Zandi, G. Natoli, and M. Karin. 1998. IKKγ is an essential regulatory subunit of the IκB kinase complex. Nature 395:297-300.
-
(1998)
Nature
, vol.395
, pp. 297-300
-
-
Rothwarf, D.M.1
Zandi, E.2
Natoli, G.3
Karin, M.4
-
61
-
-
0035958062
-
Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells
-
Sheng, H., J. Shao, and R. N. DuBois. 2001. Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells. J. Biol. Chem. 276:14498-14504.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14498-14504
-
-
Sheng, H.1
Shao, J.2
DuBois, R.N.3
-
62
-
-
0031893071
-
Lysyl oxidase: Properties, regulation and multiple functions in biology
-
Smith-Mungo, L. I., and H. M. Kagan. 1998. Lysyl oxidase: properties, regulation and multiple functions in biology. Matrix Biol. 16:387-398.
-
(1998)
Matrix Biol.
, vol.16
, pp. 387-398
-
-
Smith-Mungo, L.I.1
Kagan, H.M.2
-
63
-
-
0036241266
-
PKC-MEK-MAPK-dependent signal transduction pathway mediates the stimulation of lysyl oxidase expression by serum and PDGF in rat aortic smooth muscle cells
-
Smith-Mungo, L. I., and H. M. Kagan. 2002. PKC-MEK-MAPK-dependent signal transduction pathway mediates the stimulation of lysyl oxidase expression by serum and PDGF in rat aortic smooth muscle cells. J. Cell. Biochem. 85:775-784.
-
(2002)
J. Cell. Biochem.
, vol.85
, pp. 775-784
-
-
Smith-Mungo, L.I.1
Kagan, H.M.2
-
64
-
-
0027489006
-
Transient expression of lysyl oxidase by liver myofibroblasts in murine schistosomiasis
-
Sommer, P., C. Gleyzal, M. Raccurt, M. Delbourg, M. Serrar, P. Joazeiro, S. Peyrol, H. M. Kagan, P. C. Trackman, and J. A. Grimaud. 1993. Transient expression of lysyl oxidase by liver myofibroblasts in murine schistosomiasis. Lab. Investig. 69:460-470.
-
(1993)
Lab. Investig.
, vol.69
, pp. 460-470
-
-
Sommer, P.1
Gleyzal, C.2
Raccurt, M.3
Delbourg, M.4
Serrar, M.5
Joazeiro, P.6
Peyrol, S.7
Kagan, H.M.8
Trackman, P.C.9
Grimaud, J.A.10
-
65
-
-
0031126554
-
Rel/NF-κB transcription factors and the control of apoptosis
-
Sonenshein, G. E. 1997. Rel/NF-κB transcription factors and the control of apoptosis. Semin. Cancer Biol. 8:113-119.
-
(1997)
Semin. Cancer Biol.
, vol.8
, pp. 113-119
-
-
Sonenshein, G.E.1
-
66
-
-
0031440245
-
Aberrant nuclear factor-κB/Rel expression and the pathogenesis of breast cancer
-
Sovak, M. A., R. E. Bellas, D. W. Kim, G. J. Zanieski, A. E. Rogers, A. M. Traish, and G. E. Sonenshein. 1997. Aberrant nuclear factor-κB/Rel expression and the pathogenesis of breast cancer. J. Clin. Investig. 100:2952-2960.
-
(1997)
J. Clin. Investig.
, vol.100
, pp. 2952-2960
-
-
Sovak, M.A.1
Bellas, R.E.2
Kim, D.W.3
Zanieski, G.J.4
Rogers, A.E.5
Traish, A.M.6
Sonenshein, G.E.7
-
67
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Stokoe, D., S. G. Macdonald, K. Cadwallader, M. Symons, and J. F. Hancock. 1994. Activation of Raf as a result of recruitment to the plasma membrane. Science 264:1463-1467.
-
(1994)
Science
, vol.264
, pp. 1463-1467
-
-
Stokoe, D.1
Macdonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
68
-
-
0029882276
-
Identification of the lysyl oxidase gene as target of the anti-oncogenic transcription factor, IRF-1, and its possible role in tumor suppression
-
Tan, R. S., T. Taniguchi, and H. Harada. 1996. Identification of the lysyl oxidase gene as target of the anti-oncogenic transcription factor, IRF-1, and its possible role in tumor suppression. Cancer Res. 56:2417-2421.
-
(1996)
Cancer Res.
, vol.56
, pp. 2417-2421
-
-
Tan, R.S.1
Taniguchi, T.2
Harada, H.3
-
69
-
-
0026666773
-
Post-translational glycosylation and proteolytic processing of a lysyl oxidase precursor
-
Trackman, P. C., D. Bedell-Hogan, J. Tang, and H. M. Kagan. 1992. Post-translational glycosylation and proteolytic processing of a lysyl oxidase precursor. J. Biol. Chem. 267:8666-8671.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 8666-8671
-
-
Trackman, P.C.1
Bedell-Hogan, D.2
Tang, J.3
Kagan, H.M.4
-
70
-
-
0028978032
-
Phosphorylation of human IκBα on serines 32 and 36 controls IκBα proteolysis and NF-κB activation in response to diverse stimuli
-
Traenckner, E. B., H. L. Pahl, T. Henkel, K. N. Schmidt, S. Wilk, and P. A. Baeuerle. 1995. Phosphorylation of human IκBα on serines 32 and 36 controls IκBα proteolysis and NF-κB activation in response to diverse stimuli. EMBO J. 14:2876-2883.
-
(1995)
EMBO J.
, vol.14
, pp. 2876-2883
-
-
Traenckner, E.B.1
Pahl, H.L.2
Henkel, T.3
Schmidt, K.N.4
Wilk, S.5
Baeuerle, P.A.6
-
71
-
-
0025782658
-
NF-κB contacts DNA by a heterodimer of the p50 and p65 subunit
-
Urban, M. B., R. Schreck, and P. A. Baeuerle. 1991. NF-κB contacts DNA by a heterodimer of the p50 and p65 subunit. EMBO J. 10:1817-1825.
-
(1991)
EMBO J.
, vol.10
, pp. 1817-1825
-
-
Urban, M.B.1
Schreck, R.2
Baeuerle, P.A.3
-
72
-
-
0034653608
-
The PI3K-PDK1 connection: More than just a road to PKB
-
Vanhaesebroeck, B., and D. R. Alessi. 2000. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346:561-576.
-
(2000)
Biochem. J.
, vol.346
, pp. 561-576
-
-
Vanhaesebroeck, B.1
Alessi, D.R.2
-
73
-
-
0028971289
-
Rel/NF-κB/IκB family: Intimate tales of association and dissociation
-
Verma, I. M., J. K. Stevenson, E. M. Schwarz, D. Van Antwerp, and S. Miyamoto. 1995. Rel/NF-κB/IκB family: intimate tales of association and dissociation. Genes Dev. 9:2723-2735.
-
(1995)
Genes Dev.
, vol.9
, pp. 2723-2735
-
-
Verma, I.M.1
Stevenson, J.K.2
Schwarz, E.M.3
Van Antwerp, D.4
Miyamoto, S.5
-
74
-
-
0025043377
-
Immunohistochemical localization of lysyl oxidase with monoclonal antibodies
-
Wakasaki, H., and A. Ooshima. 1990. Immunohistochemical localization of lysyl oxidase with monoclonal antibodies. Lab. Investig. 63:377-384.
-
(1990)
Lab. Investig.
, vol.63
, pp. 377-384
-
-
Wakasaki, H.1
Ooshima, A.2
-
75
-
-
0032943591
-
The nuclear factor-κB RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells
-
Wang, W., J. L. Abbruzzese, D. B. Evans, L. Larry, K. R. Cleary, and P. J. Chiao. 1999. The nuclear factor-κB RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin. Cancer Res. 5:119-127.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 119-127
-
-
Wang, W.1
Abbruzzese, J.L.2
Evans, D.B.3
Larry, L.4
Cleary, K.R.5
Chiao, P.J.6
-
76
-
-
0033594403
-
Akt/PKB localisation and 3′ phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction
-
Watton, S. J., and J. Downward. 1999. Akt/PKB localisation and 3′ phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction. Curr. Biol. 9:433-436.
-
(1999)
Curr. Biol.
, vol.9
, pp. 433-436
-
-
Watton, S.J.1
Downward, J.2
-
77
-
-
0030611595
-
IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK
-
Woronicz, J. D., X. Gao, Z. Cao, M. Rothe, and D. V. Goeddel. 1997. IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science 278:866-869.
-
(1997)
Science
, vol.278
, pp. 866-869
-
-
Woronicz, J.D.1
Gao, X.2
Cao, Z.3
Rothe, M.4
Goeddel, D.V.5
|