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Volumn 2, Issue 3, 2003, Pages 243-258

Induction of genome instability by DNA damage in Saccharomyces cerevisiae

Author keywords

Cancer; DNA damage; Double strand breaks; Gross chromosomal rearrangement; HO endonuclease; MMS

Indexed keywords

BLEOMYCIN; CAMPTOTHECAN; CISPLATIN; DNA; DOUBLE STRANDED DNA; ENDONUCLEASE; MESYLIC ACID ETHYL ESTER; MESYLIC ACID METHYL ESTER; METHYLNITRONITROSOGUANIDINE; MUTAGENIC AGENT; UNCLASSIFIED DRUG;

EID: 0037356692     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-7864(02)00216-1     Document Type: Article
Times cited : (71)

References (71)
  • 1
    • 0032524104 scopus 로고    scopus 로고
    • Landscaping the cancer terrain
    • Kinzler K.W., Vogelstein B. Landscaping the cancer terrain. Science. 280:1998;1036-1037.
    • (1998) Science , vol.280 , pp. 1036-1037
    • Kinzler, K.W.1    Vogelstein, B.2
  • 2
    • 0032620211 scopus 로고    scopus 로고
    • Genetic disorders associated with cancer predisposition and genomic instability
    • Vessey C.J., Norbury C.J., Hickson I.D. Genetic disorders associated with cancer predisposition and genomic instability. Prog. Nucleic Acid Res. Mol. Biol. 63:1999;189-221.
    • (1999) Prog. Nucleic Acid Res. Mol. Biol. , vol.63 , pp. 189-221
    • Vessey, C.J.1    Norbury, C.J.2    Hickson, I.D.3
  • 3
    • 0033367088 scopus 로고    scopus 로고
    • The role of genomic instability in human carcinogenesis
    • Coleman W.B., Tsongalis G.J. The role of genomic instability in human carcinogenesis. Anticancer Res. 19:1999;4645-4664.
    • (1999) Anticancer Res. , vol.19 , pp. 4645-4664
    • Coleman, W.B.1    Tsongalis, G.J.2
  • 4
    • 0037178722 scopus 로고    scopus 로고
    • Maintenance of genome stability in Saccharomyces cerevisiae
    • Kolodner R.D., Putnam C.D., Myung K. Maintenance of genome stability in Saccharomyces cerevisiae. Science. 297:2002;552-557.
    • (2002) Science , vol.297 , pp. 552-557
    • Kolodner, R.D.1    Putnam, C.D.2    Myung, K.3
  • 5
    • 0029784320 scopus 로고    scopus 로고
    • Biochemistry and genetics of eukaryotic mismatch repair
    • Kolodner R. Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev. 10:1996;1433-1442.
    • (1996) Genes Dev. , vol.10 , pp. 1433-1442
    • Kolodner, R.1
  • 6
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C., Kinzler K.W., Voelstein B. Genetic instabilities in human cancers. Nature. 396:1998;643-649.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Voelstein, B.3
  • 7
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • Loeb L.A. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res. 51:1991;3075-3079.
    • (1991) Cancer Res. , vol.51 , pp. 3075-3079
    • Loeb, L.A.1
  • 9
    • 0036252540 scopus 로고    scopus 로고
    • DNA mismatch repair defects: Role in colorectal carcinogenesis
    • Jacob S., Praz F. DNA mismatch repair defects: role in colorectal carcinogenesis. Biochimie. 84:2002;27-47.
    • (2002) Biochimie , vol.84 , pp. 27-47
    • Jacob, S.1    Praz, F.2
  • 10
    • 0035093737 scopus 로고    scopus 로고
    • DNA double-strand breaks: Signaling, repair and the cancer connection
    • Khanna K.K., Jackson S.P. DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 27:2001;247-254.
    • (2001) Nat. Genet. , vol.27 , pp. 247-254
    • Khanna, K.K.1    Jackson, S.P.2
  • 11
    • 0029057336 scopus 로고
    • A single ataxia telangiectasia gene with a product similar to PI-3 kinase
    • Savitsky K.et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science. 268:1995;1749-1753.
    • (1995) Science , vol.268 , pp. 1749-1753
    • Savitsky, K.1
  • 12
    • 0035099044 scopus 로고    scopus 로고
    • BRCA2 is required for homology-directed repair of chromosomal breaks
    • Moynahan M.E., Pierce A.J., Jasin M. BRCA2 is required for homology-directed repair of chromosomal breaks. Mol. Cell. 7:2001;263-272.
    • (2001) Mol. Cell , vol.7 , pp. 263-272
    • Moynahan, M.E.1    Pierce, A.J.2    Jasin, M.3
  • 13
    • 0033544724 scopus 로고    scopus 로고
    • The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia telangiectasia-like disorder
    • Stewart G.S.et al. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia telangiectasia-like disorder. Cell. 99:1999;577-587.
    • (1999) Cell , vol.99 , pp. 577-587
    • Stewart, G.S.1
  • 14
    • 0033601346 scopus 로고    scopus 로고
    • Heterozygous germ line hCHK2 mutations in Li-Fraumini syndrome
    • Bell D.W.et al. Heterozygous germ line hCHK2 mutations in Li-Fraumini syndrome. Science. 186:1999;2528-2531.
    • (1999) Science , vol.186 , pp. 2528-2531
    • Bell, D.W.1
  • 15
    • 0032076248 scopus 로고    scopus 로고
    • The hMRE11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
    • Carney J.P.et al. The hMRE11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell. 93:1998;477-486.
    • (1998) Cell , vol.93 , pp. 477-486
    • Carney, J.P.1
  • 16
    • 0034020464 scopus 로고    scopus 로고
    • The Mre11 complex and ATM: Collaborating to navigate S-phase
    • Petrini J.H.J. The Mre11 complex and ATM: collaborating to navigate S-phase. Curr. Opin. Cell Biol. 12:2000;293-296.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 293-296
    • Petrini, J.H.J.1
  • 17
    • 0034106722 scopus 로고    scopus 로고
    • ATM-dependent phosphorylation of nibrin in response to radiation exposure
    • Gatei M.et al. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nat. Genet. 25:2000;115-119.
    • (2000) Nat. Genet. , vol.25 , pp. 115-119
    • Gatei, M.1
  • 18
    • 0034713466 scopus 로고    scopus 로고
    • ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response
    • Wu X.et al. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature. 405:2000;477-482.
    • (2000) Nature , vol.405 , pp. 477-482
    • Wu, X.1
  • 19
    • 0033618621 scopus 로고    scopus 로고
    • Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response
    • Zhong Q.et al. Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response. Science. 285:1999;747-750.
    • (1999) Science , vol.285 , pp. 747-750
    • Zhong, Q.1
  • 20
    • 0033527717 scopus 로고    scopus 로고
    • Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
    • Cortez D., Wang Y., Qin J., Elledge S.J. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science. 286:1999;1162-1166.
    • (1999) Science , vol.286 , pp. 1162-1166
    • Cortez, D.1    Wang, Y.2    Qin, J.3    Elledge, S.J.4
  • 21
    • 0032860479 scopus 로고    scopus 로고
    • Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
    • Chen C., Kolodner R.D. Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat. Genet. 23:1999;81-85.
    • (1999) Nat. Genet. , vol.23 , pp. 81-85
    • Chen, C.1    Kolodner, R.D.2
  • 22
    • 0035158640 scopus 로고    scopus 로고
    • SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, functions in the suppression of genome instability and homeologous recombination
    • Myung K., Datta A., Chen C., Kolodner R.D. SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, functions in the suppression of genome instability and homeologous recombination. Nat. Genet. 27:2001;113-116.
    • (2001) Nat. Genet. , vol.27 , pp. 113-116
    • Myung, K.1    Datta, A.2    Chen, C.3    Kolodner, R.D.4
  • 23
    • 0035830498 scopus 로고    scopus 로고
    • Suppression of spontaneous chromosomal rearrangements by the S-phase checkpoint in Saccharomyces cerevisiae
    • Myung K., Datta A., Kolodner R.D. Suppression of spontaneous chromosomal rearrangements by the S-phase checkpoint in Saccharomyces cerevisiae. Cell. 104:2001;397-408.
    • (2001) Cell , vol.104 , pp. 397-408
    • Myung, K.1    Datta, A.2    Kolodner, R.D.3
  • 24
    • 0035963338 scopus 로고    scopus 로고
    • Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae
    • Myung K., Chen C., Kolodner R.D. Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae. Nature. 411:2001;1073-1076.
    • (2001) Nature , vol.411 , pp. 1073-1076
    • Myung, K.1    Chen, C.2    Kolodner, R.D.3
  • 25
    • 0037007074 scopus 로고    scopus 로고
    • Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae
    • Myung K., Kolodner R.D. Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 99:2002;4500-4507.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 4500-4507
    • Myung, K.1    Kolodner, R.D.2
  • 26
    • 0034733498 scopus 로고    scopus 로고
    • Lucky breaks: Analysis of recombination in Saccharomyces
    • Haber J.E. Lucky breaks: analysis of recombination in Saccharomyces. Mutat. Res. 451:2000;53-69.
    • (2000) Mutat. Res. , vol.451 , pp. 53-69
    • Haber, J.E.1
  • 27
    • 0034922586 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit increased rates of homology-directed translocations
    • Fasullo M., Giallanza P., Dong Z., Cera C., Bennett T. Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit increased rates of homology-directed translocations. Genetics. 158:2001;959-972.
    • (2001) Genetics , vol.158 , pp. 959-972
    • Fasullo, M.1    Giallanza, P.2    Dong, Z.3    Cera, C.4    Bennett, T.5
  • 28
    • 0024027329 scopus 로고
    • Physical monitoring of mating type switching in Saccharomyces cerevisiae
    • Connolly B., White C.I., Haber J.E. Physical monitoring of mating type switching in Saccharomyces cerevisiae. Mol. Cell. Biol. 8:1988;2342-2349.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 2342-2349
    • Connolly, B.1    White, C.I.2    Haber, J.E.3
  • 29
    • 0024403230 scopus 로고
    • Double-strand breaks stimulate alternative mechanisms of recombination repair
    • Nickoloff J.A., Singer J.D., Hoekstra M.F., Heffron F. Double-strand breaks stimulate alternative mechanisms of recombination repair. J. Mol. Biol. 207:1989;527-541.
    • (1989) J. Mol. Biol. , vol.207 , pp. 527-541
    • Nickoloff, J.A.1    Singer, J.D.2    Hoekstra, M.F.3    Heffron, F.4
  • 30
    • 0024847277 scopus 로고
    • Analysis of the HO-cleaved MAT DNA intermediate generated during the mating type switch in the yeast Saccharomyces cerevisiae
    • Raveh D., Hughes S.H., Shafer B.K., Strathern J.N. Analysis of the HO-cleaved MAT DNA intermediate generated during the mating type switch in the yeast Saccharomyces cerevisiae. Mol. Gen. Genet. 220:1989;33-42.
    • (1989) Mol. Gen. Genet. , vol.220 , pp. 33-42
    • Raveh, D.1    Hughes, S.H.2    Shafer, B.K.3    Strathern, J.N.4
  • 31
    • 0023813873 scopus 로고
    • Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences
    • Rudin N., Haber J.E. Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences. Mol. Cell. Biol. 8:1988;3918-3928.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3918-3928
    • Rudin, N.1    Haber, J.E.2
  • 32
    • 0024693555 scopus 로고
    • Genetic and physical analysis of double-strand break repair and recombination in Saccharomyces cerevisiae
    • Rudin N., Sugarman E., Haber J.E. Genetic and physical analysis of double-strand break repair and recombination in Saccharomyces cerevisiae. Genetics. 122:1989;519-534.
    • (1989) Genetics , vol.122 , pp. 519-534
    • Rudin, N.1    Sugarman, E.2    Haber, J.E.3
  • 33
    • 0025020278 scopus 로고
    • Intermediates of recombination during mating type switching in Saccharomyces cerevisiae
    • White C.I., Haber J.E. Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J. 9:1990;663-673.
    • (1990) EMBO J. , vol.9 , pp. 663-673
    • White, C.I.1    Haber, J.E.2
  • 34
    • 0029975794 scopus 로고    scopus 로고
    • Retrotransposon reverse-transcriptase-mediated repair of chromosomal breaks
    • Teng S.C., Kim B., Gabriel A. Retrotransposon reverse-transcriptase-mediated repair of chromosomal breaks. Nature. 383:1996;641-644.
    • (1996) Nature , vol.383 , pp. 641-644
    • Teng, S.C.1    Kim, B.2    Gabriel, A.3
  • 35
    • 0030031522 scopus 로고    scopus 로고
    • Effects of mutations of RAD50, RAD51, RAD52 and related genes on illegitimate recombination in Saccharomyces cerevisiae
    • Tsukamoto Y., Kato J., Ikeda H. Effects of mutations of RAD50, RAD51, RAD52 and related genes on illegitimate recombination in Saccharomyces cerevisiae. Genetics. 142:1996;383-391.
    • (1996) Genetics , vol.142 , pp. 383-391
    • Tsukamoto, Y.1    Kato, J.2    Ikeda, H.3
  • 36
    • 0029976325 scopus 로고    scopus 로고
    • Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
    • Moore J.K., Haber J.E. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:1996;2164-2173.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2164-2173
    • Moore, J.K.1    Haber, J.E.2
  • 37
    • 0029970701 scopus 로고    scopus 로고
    • Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks
    • Moore J.K., Haber J.E. Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks. Nature. 383:1996;644-646.
    • (1996) Nature , vol.383 , pp. 644-646
    • Moore, J.K.1    Haber, J.E.2
  • 38
    • 0028013486 scopus 로고
    • Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events
    • Kramer K.M., Brock J.A., Bloom K., Moore J.K., Haber J.E. Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events. Mol. Cell. Biol. 14:1994;1293-1301.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1293-1301
    • Kramer, K.M.1    Brock, J.A.2    Bloom, K.3    Moore, J.K.4    Haber, J.E.5
  • 39
    • 0031737723 scopus 로고    scopus 로고
    • Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture
    • Bosco G., Haber J.E. Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. Genetics. 150:1998;1037-1047.
    • (1998) Genetics , vol.150 , pp. 1037-1047
    • Bosco, G.1    Haber, J.E.2
  • 40
    • 0032493889 scopus 로고    scopus 로고
    • Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
    • Lee S.E., Moore J.K., Holmes A., Umezu K., Kolodner R.D., Haber J.E. Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell. 94:1998;399-409.
    • (1998) Cell , vol.94 , pp. 399-409
    • Lee, S.E.1    Moore, J.K.2    Holmes, A.3    Umezu, K.4    Kolodner, R.D.5    Haber, J.E.6
  • 41
    • 0032536861 scopus 로고    scopus 로고
    • Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
    • Boulton S.J., Jackson S.P. Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J. 17:1998;1819-1828.
    • (1998) EMBO J. , vol.17 , pp. 1819-1828
    • Boulton, S.J.1    Jackson, S.P.2
  • 43
  • 44
    • 0035822079 scopus 로고    scopus 로고
    • Defects in mismatch repair promote telomerase-independent proliferation
    • Rizki A., Lundblad V. Defects in mismatch repair promote telomerase-independent proliferation. Nature. 411:2001;713-716.
    • (2001) Nature , vol.411 , pp. 713-716
    • Rizki, A.1    Lundblad, V.2
  • 45
    • 0031036995 scopus 로고    scopus 로고
    • RAD9, RAD17 and RAD24 are required for S-phase regulation in Saccharomyces cerevisiae in response to DNA damage
    • Paulovich A.G., Margulies R.U., Garvik B.M., Hartwell L.H. RAD9, RAD17 and RAD24 are required for S-phase regulation in Saccharomyces cerevisiae in response to DNA damage. Genetics. 145:1997;45-62.
    • (1997) Genetics , vol.145 , pp. 45-62
    • Paulovich, A.G.1    Margulies, R.U.2    Garvik, B.M.3    Hartwell, L.H.4
  • 46
    • 0033957793 scopus 로고    scopus 로고
    • The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci
    • Frei C., Gasser S.M. The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev. 14:2000;81-96.
    • (2000) Genes Dev. , vol.14 , pp. 81-96
    • Frei, C.1    Gasser, S.M.2
  • 47
    • 0034881760 scopus 로고    scopus 로고
    • Budding yeast Rad9 is an ATP-dependent Rad53 activating machine
    • Gilbert C.S., Green C.M., Lowndes N.F. Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. Mol. Cell. 8:2001;129-136.
    • (2001) Mol. Cell , vol.8 , pp. 129-136
    • Gilbert, C.S.1    Green, C.M.2    Lowndes, N.F.3
  • 48
    • 0034964498 scopus 로고    scopus 로고
    • A DNA damage response pathway controlled by Tel1 and the Mre11 complex
    • Usui T., Ogawa H., Petrini J.H.J. A DNA damage response pathway controlled by Tel1 and the Mre11 complex. Mol. Cell. 7:2001;1255-1266.
    • (2001) Mol. Cell , vol.7 , pp. 1255-1266
    • Usui, T.1    Ogawa, H.2    Petrini, J.H.J.3
  • 49
    • 0032567041 scopus 로고    scopus 로고
    • The many interfaces of Mre11
    • Haber J. The many interfaces of Mre11. Cell. 95:1998;583-586.
    • (1998) Cell , vol.95 , pp. 583-586
    • Haber, J.1
  • 50
    • 0030849085 scopus 로고    scopus 로고
    • Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break-repair
    • Teo S.H., Jackson S.P. Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break-repair. EMBO J. 16:1997;4788-4795.
    • (1997) EMBO J. , vol.16 , pp. 4788-4795
    • Teo, S.H.1    Jackson, S.P.2
  • 51
    • 0029954821 scopus 로고    scopus 로고
    • Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae
    • Milne G.T., Jin S., Shannon K.B., Weaver D.T. Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:1996;4189-4198.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4189-4198
    • Milne, G.T.1    Jin, S.2    Shannon, K.B.3    Weaver, D.T.4
  • 52
    • 0029947714 scopus 로고    scopus 로고
    • Double-strand break repair in the absence of RAD51 in yeast: A possible role for break-induced DNA replication
    • Malkova A., Ivanov E.L., Haber J.E. Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc. Natl. Acad. Sci. U.S.A. 93:1996;7131-7136.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 7131-7136
    • Malkova, A.1    Ivanov, E.L.2    Haber, J.E.3
  • 53
    • 0035000154 scopus 로고    scopus 로고
    • Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break
    • Signon L., Malkova A., Naylor M.L., Klein H., Haber J.E. Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break. Mol. Cell. Biol. 21:2001;2048-2056.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2048-2056
    • Signon, L.1    Malkova, A.2    Naylor, M.L.3    Klein, H.4    Haber, J.E.5
  • 54
    • 0035338254 scopus 로고    scopus 로고
    • RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site
    • Malkova A., Signon L., Schaefer C.B., Naylor M.L., Theis J.F., Newlon C.S., Haber J.E. RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site. Genes Dev. 15:2001;1055-1060.
    • (2001) Genes Dev. , vol.15 , pp. 1055-1060
    • Malkova, A.1    Signon, L.2    Schaefer, C.B.3    Naylor, M.L.4    Theis, J.F.5    Newlon, C.S.6    Haber, J.E.7
  • 55
    • 0032109778 scopus 로고    scopus 로고
    • Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair
    • Chen C., Umezu K., Kolodner R.D. Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair. Mol. Cell. 2:1998;9-22.
    • (1998) Mol. Cell , vol.2 , pp. 9-22
    • Chen, C.1    Umezu, K.2    Kolodner, R.D.3
  • 56
    • 0012814352 scopus 로고
    • Approaches to chemical dosimetry in mutagenesis and carcinogenesis: The relevance of reactions of chemical mutagens and carcinogens in DNA
    • P.L. Grover (Ed.), CRC Press, Boca Raton, FL
    • P.D. Lawley, Approaches to chemical dosimetry in mutagenesis and carcinogenesis: the relevance of reactions of chemical mutagens and carcinogens in DNA, in: P.L. Grover (Ed.), Chemical Carcinogens and DNA, CRC Press, Boca Raton, FL, 1979, pp. 1-79.
    • (1979) Chemical Carcinogens and DNA , pp. 1-79
    • Lawley, P.D.1
  • 57
    • 0021717853 scopus 로고
    • A review of the genetic effects of ethyl methane sulfonate
    • Sega G.A. A review of the genetic effects of ethyl methane sulfonate. Mutat. Res. 134:1984;113-142.
    • (1984) Mutat. Res. , vol.134 , pp. 113-142
    • Sega, G.A.1
  • 60
    • 0034733497 scopus 로고    scopus 로고
    • Tying up loose ends: Nonhomologous end-joining in Saccharomyces cerevisiae
    • Lewis L.K., Resnick M.A. Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae. Mutat. Res. 451:2000;71-89.
    • (2000) Mutat. Res. , vol.451 , pp. 71-89
    • Lewis, L.K.1    Resnick, M.A.2
  • 61
    • 0033598944 scopus 로고    scopus 로고
    • Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases α and δ
    • Diede S.J., Gottschling D.E. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases α and δ Cell. 99:1999;723-733.
    • (1999) Cell , vol.99 , pp. 723-733
    • Diede, S.J.1    Gottschling, D.E.2
  • 62
    • 0009356799 scopus 로고
    • A 24-base-pair DNA sequence from the MAT locus stimulates intergenic recombination in yeast
    • Nickolff J.A., Chen E.Y., Heffron F. A 24-base-pair DNA sequence from the MAT locus stimulates intergenic recombination in yeast. Proc. Natl. Acad. Sci. U.S.A. 83:1986;7831-7835.
    • (1986) Proc. Natl. Acad. Sci. U.S.A. , vol.83 , pp. 7831-7835
    • Nickolff, J.A.1    Chen, E.Y.2    Heffron, F.3
  • 63
    • 0032538880 scopus 로고    scopus 로고
    • Replication errors: Cha(lle)nging the genome
    • Jiricny J. Replication errors: cha(lle)nging the genome. EMBO J. 17:1998;6427-6436.
    • (1998) EMBO J. , vol.17 , pp. 6427-6436
    • Jiricny, J.1
  • 64
    • 0032605986 scopus 로고    scopus 로고
    • A survey of the sequence-specific interaction of damaging agents with DNA: Emphasis on antitumor agents
    • Murray V. A survey of the sequence-specific interaction of damaging agents with DNA: emphasis on antitumor agents. Prog. Nucleic Acid Res. Mol. Biol. 63:1999;367-415.
    • (1999) Prog. Nucleic Acid Res. Mol. Biol. , vol.63 , pp. 367-415
    • Murray, V.1
  • 65
    • 0036053548 scopus 로고    scopus 로고
    • Mobile genetic element activation and genotoxic cancer therapy: Potential clinical implications
    • Hagan C.R., Rudin C.M. Mobile genetic element activation and genotoxic cancer therapy: potential clinical implications. Am. J. Pharmacogenom. 2:2002;25-35.
    • (2002) Am. J. Pharmacogenom. , vol.2 , pp. 25-35
    • Hagan, C.R.1    Rudin, C.M.2
  • 66
    • 0031879996 scopus 로고    scopus 로고
    • Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene, MDR1/P-glycoprotein, in drug-selected cell lines and patients with drug refractory ALL
    • Knutsen T. Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene, MDR1/P-glycoprotein, in drug-selected cell lines and patients with drug refractory ALL. Genes Chromosomes Cancer. 23:1998;44-54.
    • (1998) Genes Chromosomes Cancer , vol.23 , pp. 44-54
    • Knutsen, T.1
  • 67
    • 0035056832 scopus 로고    scopus 로고
    • Leukemias related to treatment with DNA topoisomerase II inhibitors
    • Felix C.A. Leukemias related to treatment with DNA topoisomerase II inhibitors. Med. Pediatr. Oncol. 36:2001;525-535.
    • (2001) Med. Pediatr. Oncol. , vol.36 , pp. 525-535
    • Felix, C.A.1
  • 68
    • 0034937435 scopus 로고    scopus 로고
    • Analysis of Vγ/Jβ trans-rearrangements in paediatric patients undergoing chemotherapy
    • Lopes L.F., Neto E.D., Lorand-Metze I., Latorre M.R., Simpson A.J. Analysis of Vγ/Jβ trans-rearrangements in paediatric patients undergoing chemotherapy. Br. J. Haematol. 113:2001;1001-1008.
    • (2001) Br. J. Haematol. , vol.113 , pp. 1001-1008
    • Lopes, L.F.1    Neto, E.D.2    Lorand-Metze, I.3    Latorre, M.R.4    Simpson, A.J.5
  • 69
    • 0036371064 scopus 로고    scopus 로고
    • Therapy-related myelodysplastic syndrome in a case of cutaneous adult T-cell lymphoma
    • Fukuda N., Shinohara K., Ota I., Muraki K., Shimohakamada Y. Therapy-related myelodysplastic syndrome in a case of cutaneous adult T-cell lymphoma. Int. J. Hematol. 75:2002;67-71.
    • (2002) Int. J. Hematol. , vol.75 , pp. 67-71
    • Fukuda, N.1    Shinohara, K.2    Ota, I.3    Muraki, K.4    Shimohakamada, Y.5
  • 70
    • 0036248962 scopus 로고    scopus 로고
    • Advances in the understanding and management of acute promyelocytic leukemia
    • Mandelli F., Avvisati G., Lo Coco F. Advances in the understanding and management of acute promyelocytic leukemia. Rev. Clin. Exp. Hematol. 6:2002;60-71.
    • (2002) Rev. Clin. Exp. Hematol. , vol.6 , pp. 60-71
    • Mandelli, F.1    Avvisati, G.2    Lo Coco, F.3


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