-
1
-
-
0027982876
-
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
-
SPRINGER TA: Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell (1994) 76:301-314. An excellent review of leukocyte trafficking components.
-
(1994)
Cell
, vol.76
, pp. 301-314
-
-
Springer, T.A.1
-
2
-
-
0030001675
-
Lymphocyte homing and homeostasis
-
BUTCHER EC, PICKER LJ: Lymphocyte homing and homeostasis. Science (1996) 272:60-66. An excellent review of leukocyte homing regulation.
-
(1996)
Science
, vol.272
, pp. 60-66
-
-
Butcher, E.C.1
Picker, L.J.2
-
3
-
-
0025854524
-
Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins
-
LAWRENCE MB, SPRINGER TA: Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell (1991) 65:859-873.
-
(1991)
Cell
, vol.65
, pp. 859-873
-
-
Lawrence, M.B.1
Springer, T.A.2
-
4
-
-
0029858031
-
Selectins and their ligands: Current concepts and controversies
-
KANSAS GS: Selectins and their ligands: current concepts and controversies. Blood (1996) 88:3259-3287.
-
(1996)
Blood
, vol.88
, pp. 3259-3287
-
-
Kansas, G.S.1
-
5
-
-
1842413033
-
Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells
-
FUHLBRIGGE RC, KIEFFER JD, ARMERDING D, KUPPER TS: Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells. Nature (1997) 389:978-981.
-
(1997)
Nature
, vol.389
, pp. 978-981
-
-
Fuhlbrigge, R.C.1
Kieffer, J.D.2
Armerding, D.3
Kupper, T.S.4
-
6
-
-
0032528562
-
CD4+ T cells migrate into inflamed skin only if they express ligands for E- and P-selectin
-
TIETZ W, ALLEMAND Y, BORGES E et al.: CD4+ T cells migrate into inflamed skin only if they express ligands for E- and P-selectin. J. Immunol. (1998) 161:963-970.
-
(1998)
J. Immunol.
, vol.161
, pp. 963-970
-
-
Tietz, W.1
Allemand, Y.2
Borges, E.3
-
7
-
-
0035025761
-
Chemokines, chemokine receptors, and allograft rejection
-
NELSON PJ, KRENSKY AM: Chemokines, chemokine receptors, and allograft rejection. Immunity (2001) 14:377-386.
-
(2001)
Immunity
, vol.14
, pp. 377-386
-
-
Nelson, P.J.1
Krensky, A.M.2
-
8
-
-
0022574146
-
Induction by IL-1 and interferon-gamma: Tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1)
-
DUSTIN ML, ROTHLEIN R, BAHN AK, DINARELLO CA, SPRINGER TA: Induction by IL-1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. (1986) 137:245-254.
-
(1986)
J. Immunol.
, vol.137
, pp. 245-254
-
-
Dustin, M.L.1
Rothlein, R.2
Bahn, A.K.3
Dinarello, C.A.4
Springer, T.A.5
-
9
-
-
0024818401
-
Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes
-
OSBORN L, HESSION C, TIZARD R et al.: Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell (1989) 59:1203-1211.
-
(1989)
Cell
, vol.59
, pp. 1203-1211
-
-
Osborn, L.1
Hession, C.2
Tizard, R.3
-
10
-
-
0034507687
-
Chemokines trigger immediate β2 integrin affinity and mobility changes: Differential regulation and roles in lymphocyte arrest under flow
-
CONSTANTIN G, MAJEED M, GIAGULLI C et al.: Chemokines trigger immediate β2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow. Immunity (2000) 13:759-769.
-
(2000)
Immunity
, vol.13
, pp. 759-769
-
-
Constantin, G.1
Majeed, M.2
Giagulli, C.3
-
11
-
-
0027458070
-
Expression of adhesion molecules in allograft renal dysfunction a distinct diagnostic pattern in rejection and cyclosporine nephrotoxicity
-
MAMPASO F, SANCHEZ-MADRID F, MARCEN R et al.: Expression of adhesion molecules in allograft renal dysfunction a distinct diagnostic pattern in rejection and cyclosporine nephrotoxicity. Transplantation (1993) 56:687-691.
-
(1993)
Transplantation
, vol.56
, pp. 687-691
-
-
Mampaso, F.1
Sanchez-Madrid, F.2
Marcen, R.3
-
12
-
-
0030975020
-
The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney, inhibition by a soluble P-selectin ligand
-
TAKADA M, NADEAU KC, SHAW GD, MARQUETTE KA, TILNEY NL: The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney, inhibition by a soluble P-selectin ligand. J. Clin. Invest. (1997) 99:2682-2690.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2682-2690
-
-
Takada, M.1
Nadeau, K.C.2
Shaw, G.D.3
Marquette, K.A.4
Tilney, N.L.5
-
13
-
-
0025736324
-
Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissue
-
KOCH AE, BURROWS JC, HAINES GK, CARLOS TM, HARLAN JM, LEIBOVICH J: Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissue. Lab. Invest. (1991) 64:343-320.
-
(1991)
Lab. Invest.
, vol.64
, pp. 343-320
-
-
Koch, A.E.1
Burrows, J.C.2
Haines, G.K.3
Carlos, T.M.4
Harlan, J.M.5
Leibovich, J.6
-
14
-
-
0028335730
-
Increased expression of adhesion receptors in both lesional and non-lesional psoriatic skin
-
DE BOER OJ, WAKELKAMP IMM J, PALS ST, CLAESSEN N, BOS JD, DAS PK: Increased expression of adhesion receptors in both lesional and non-lesional psoriatic skin. Arch. Dermatol. Res. (1994) 286:304-311.
-
(1994)
Arch. Dermatol. Res.
, vol.286
, pp. 304-311
-
-
De Boer, O.J.1
Wakelkamp, I.M.M.J.2
Pals, S.T.3
Claessen, N.4
Bos, J.D.5
Das, P.K.6
-
15
-
-
0028941871
-
The adhesion molecule and cytokine profile of multiple sclerosis lesions
-
CANNELLA B, RAINE CS: The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann. Neurol. (1995) 37:424-435.
-
(1995)
Ann. Neurol.
, vol.37
, pp. 424-435
-
-
Cannella, B.1
Raine, C.S.2
-
16
-
-
0031012138
-
P- and E-selectin mediate recruitment of T-helper-1 but notT-helper-2 cells into inflamed tissues
-
AUSTRUP F, VESTWEBER D, BORGES E et al.: P- and E-selectin mediate recruitment of T-helper-1 but notT-helper-2 cells into inflamed tissues. Nature (1997) 385:81-83. T cell trafficking to inflamed tissue is controlled in part by selectin expression.
-
(1997)
Nature
, vol.385
, pp. 81-83
-
-
Austrup, F.1
Vestweber, D.2
Borges, E.3
-
17
-
-
0034966570
-
E-selectin, but not P-selectin, is required for development of adjuvant-induced arthritis in the rat
-
ISSEKUTZ AC, MU JY, MELROSE J, BERG EL: E-selectin, but not P-selectin, is required for development of adjuvant-induced arthritis in the rat. Arthritis Rheum. (2001) 44:1428-1437.
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 1428-1437
-
-
Issekutz, A.C.1
Mu, J.Y.2
Melrose, J.3
Berg, E.L.4
-
18
-
-
0030726193
-
E- and P-selectin are not involved in the recruitment of inflammatory cells across the blood-brain barrier in experimental autoimmune encephalomyelitis
-
ENGELHARDT B, VESTWEBER D, HALLMANN R, SCHULTZ M: E- and P-selectin are not involved in the recruitment of inflammatory cells across the blood-brain barrier in experimental autoimmune encephalomyelitis. Blood (1997) 90:4459-4472.
-
(1997)
Blood
, vol.90
, pp. 4459-4472
-
-
Engelhardt, B.1
Vestweber, D.2
Hallmann, R.3
Schultz, M.4
-
19
-
-
0027248939
-
Attenuation of colitis in the cotton-top tamarin by anti-α4 integrin monoclonal antibody
-
PODOLSKY DK, LOBB R, KING N et al.: Attenuation of colitis in the cotton-top tamarin by anti-α4 integrin monoclonal antibody. J. Clin. Invest. (1993) 92:372-380.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 372-380
-
-
Podolsky, D.K.1
Lobb, R.2
King, N.3
-
20
-
-
0036105980
-
Anti-E-selectin is ineffective in the treatment of psoriasis: A randomized trial
-
BHUSHAN M, BLEIKER TO, BALLSDON AE et al.: Anti-E-selectin is ineffective in the treatment of psoriasis: a randomized trial. Br. J. Dermatol. (2002) 146:824-831.
-
(2002)
Br. J. Dermatol.
, vol.146
, pp. 824-831
-
-
Bhushan, M.1
Bleiker, T.O.2
Ballsdon, A.E.3
-
21
-
-
0028984949
-
α4 integrins mediate lymphocyte attachment and rolling under physiologic flow
-
BERLIN C, BARGATZE RF, CAMPBELL JJ et al.: α4 integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell (1995) 80:413-422.
-
(1995)
Cell
, vol.80
, pp. 413-422
-
-
Berlin, C.1
Bargatze, R.F.2
Campbell, J.J.3
-
22
-
-
0030030905
-
Susceptibility to infection and altered hematopoesis in mice deficient in both P- and E-selectins
-
FRENETTE PS, MAYADAS TN, RAYBURN H, HYNES RO, WAGNER DD: Susceptibility to infection and altered hematopoesis in mice deficient in both P- and E-selectins. Cell (1996) 84:563-574.
-
(1996)
Cell
, vol.84
, pp. 563-574
-
-
Frenette, P.S.1
Mayadas, T.N.2
Rayburn, H.3
Hynes, R.O.4
Wagner, D.D.5
-
23
-
-
0026448082
-
Brief report: Recurrent severe infections caused by a novel leukocyte adhesion deficiency
-
ETZIONI A, FRYDMAN M, POLLACK S et al.: Brief report: recurrent severe infections caused by a novel leukocyte adhesion deficiency, N. Engl. J. Med. (1992) 327:1789-1792.
-
(1992)
N. Engl. J. Med.
, vol.327
, pp. 1789-1792
-
-
Etzioni, A.1
Frydman, M.2
Pollack, S.3
-
24
-
-
0027164220
-
In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury
-
WEYRICH AS, MA X-L, LEFER DJ, ALBERTINE KH, LEFER AM: In vivo neutralization of P-selectin protects feline heart and endothelium. in myocardial ischemia and reperfusion injury. J. Clin. Invest. (1993) 91:2620-2629.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 2620-2629
-
-
Weyrich, A.S.1
Ma, X.-L.2
Lefer, D.J.3
Albertine, K.H.4
Lefer, A.M.5
-
25
-
-
0034002577
-
Activation of inflammatory mediators in rat renal isografts by donor brain death
-
KUSAKA M, PRATSCHKE J, WILHELM MJ et al.: Activation of inflammatory mediators in rat renal isografts by donor brain death. Transplantation (2000) 69:405-410.
-
(2000)
Transplantation
, vol.69
, pp. 405-410
-
-
Kusaka, M.1
Pratschke, J.2
Wilhelm, M.J.3
-
26
-
-
0027362687
-
Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear
-
WINN RK, LIGGITT D, VEDDER NB, PAULSON JC, HARLAN JM: Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear. J. Clin. Invest. (1993) 92:2042-2047.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 2042-2047
-
-
Winn, R.K.1
Liggitt, D.2
Vedder, N.B.3
Paulson, J.C.4
Harlan, J.M.5
-
27
-
-
0036212055
-
The effect of adhesion molecule blockade on pulmonary reperfusion injury
-
LEVINE AJ, PARKES K, ROONEY SJ, BONSER RS: The effect of adhesion molecule blockade on pulmonary reperfusion injury. Ann. Thorac. Surg. (2002) 73:1101-1106.
-
(2002)
Ann. Thorac. Surg.
, vol.73
, pp. 1101-1106
-
-
Levine, A.J.1
Parkes, K.2
Rooney, S.J.3
Bonser, R.S.4
-
28
-
-
0035212973
-
Improvements in early behavior of rat kidney allografts after treatment of the brain-dead donor
-
PRATSCHKE J, KOLFA G, WILHELM MJ et al.: Improvements in early behavior of rat kidney allografts after treatment of the brain-dead donor. Ann. Surg. (2001) 234:732-740. Immune rejection in the host can be modified by inhibiting selectin-mediated neutrophil trafficking in the donor.
-
(2001)
Ann. Surg.
, vol.234
, pp. 732-740
-
-
Pratschke, J.1
Kolfa, G.2
Wilhelm, M.J.3
-
29
-
-
0025182959
-
Adhesion receptors of the immune system
-
SPRINGER TA: Adhesion receptors of the immune system. Nature (1990) 346:425-434.
-
(1990)
Nature
, vol.346
, pp. 425-434
-
-
Springer, T.A.1
-
30
-
-
0024564492
-
Endothelial-leukocyte adhesion molecule-1-dependent and leukocyte (CD11/CD18)-dependent mechanisms contribute to polmorphonuctear lukocyte adhesion to cytokine-activated human vascular endothelium
-
LUSCINSKAS FW, BROCK AF, ARNAOUT MA, GIMBRONE MA: Endothelial-leukocyte adhesion molecule-1-dependent and leukocyte (CD11/CD18)-dependent mechanisms contribute to polmorphonuctear lukocyte adhesion to cytokine-activated human vascular endothelium. J. Immunol. (1989) 142:2257-2263.
-
(1989)
J. Immunol.
, vol.142
, pp. 2257-2263
-
-
Luscinskas, F.W.1
Brock, A.F.2
Arnaout, M.A.3
Gimbrone, M.A.4
-
31
-
-
0025276082
-
Inhibition of leukocyte adherence by anti-CD18 monoclonal antibody attenuates reperfusion injury in the rabbit ear
-
VEDDER NB, WINN RK, RICE CL, CHI EY, ARFORS K-E, HARLAN JM: Inhibition of leukocyte adherence by anti-CD18 monoclonal antibody attenuates reperfusion injury in the rabbit ear. Proc. Natl. Acad. Sci. USA (1990) 87:2643-2646.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2643-2646
-
-
Vedder, N.B.1
Winn, R.K.2
Rice, C.L.3
Chi, E.Y.4
Arfors, K.-E.5
Harlan, J.M.6
-
32
-
-
0026329185
-
A CD18 monoclonal antibody increases the incidence and severity of subcutaneous abscess formation after high-dose Staphylococcus aureus injection in rabbits
-
SHARAR SR, WINN RK, MURRY CE, HARLAN JM, RICE CL: A CD18 monoclonal antibody increases the incidence and severity of subcutaneous abscess formation after high-dose Staphylococcus aureus injection in rabbits. Surgery (1991) 110:213-220.
-
(1991)
Surgery
, vol.110
, pp. 213-220
-
-
Sharar, S.R.1
Winn, R.K.2
Murry, C.E.3
Harlan, J.M.4
Rice, C.L.5
-
33
-
-
18244415152
-
Spontaneous skin ulceration and defective T cell function in CD18 null mice
-
SCHARFFETTER-KOCHANEK K, LU H, NORMAN K et al.: Spontaneous skin ulceration and defective T cell function in CD18 null mice. J. Exp. Med. (1998) 188:119-131.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 119-131
-
-
Scharffetter-Kochanek, K.1
Lu, H.2
Norman, K.3
-
34
-
-
0023083976
-
Leukocyte adhesion deficiency: An inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins
-
ANDERSON DC, SPRINGER TA: Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins. Ann. Rev. Med. (1987) 38:175-194.
-
(1987)
Ann. Rev. Med.
, vol.38
, pp. 175-194
-
-
Anderson, D.C.1
Springer, T.A.2
-
35
-
-
0036008013
-
JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes
-
OSTERMANN G, WEBER KSC, ZERNECKE A, SCHRÖDER A, WEBER C: JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes. Nat. Immunol. (2002) 3:151-158.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 151-158
-
-
Ostermann, G.1
Weber, K.S.C.2
Zernecke, A.3
Schröder, A.4
Weber, C.5
-
36
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
GRAKOUI A, BROMLEY SK, SUMEN C et al.: The immunological synapse: a molecular machine controlling T cell activation. Science (1999) 285:221-227.
-
(1999)
Science
, vol.285
, pp. 221-227
-
-
Grakoui, A.1
Bromley, S.K.2
Sumen, C.3
-
37
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
MONKS CR, FREIBERG BA, KUPFER H, SCIAKY N, KUPFER A: Three-dimensional segregation of supramolecular activation clusters in T cells. Nature (1998) 395:82-86.
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
38
-
-
0023182607
-
The role of monocyte lymphocyte-associated antigen 1 (LFA-1) in accessory cell function
-
DOUGHERTY GJ, HOGG N: The role of monocyte lymphocyte-associated antigen 1 (LFA-1) in accessory cell function. Eur. J. Immunol. (1987) 17:943-947.
-
(1987)
Eur. J. Immunol.
, vol.17
, pp. 943-947
-
-
Dougherty, G.J.1
Hogg, N.2
-
39
-
-
0019448315
-
Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA-1): Mechanism of blockade of T lymphocyte-mediated killing and effects on other T and B lymphocyte functions
-
DAVIGNON D, MARTZ E, REYNOLDS T, KURZINGER K, SPRINGER TA: Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA-1): mechanism of blockade of T lymphocyte-mediated killing and effects on other T and B lymphocyte functions. J. Immunol. (1981) 127:590-595.
-
(1981)
J. Immunol.
, vol.127
, pp. 590-595
-
-
Davignon, D.1
Martz, E.2
Reynolds, T.3
Kurzinger, K.4
Springer, T.A.5
-
40
-
-
0035746070
-
Anti-adhesion antibodies: Efalizumab, a humanized anti-CD11a monoclonal antibody
-
DEDRICK RL, WALICKE P, GAROVOY M: Anti-adhesion antibodies: efalizumab, a humanized anti-CD11a monoclonal antibody. Transpl. Immunol. (2002) 9:181-186.
-
(2002)
Transpl. Immunol.
, vol.9
, pp. 181-186
-
-
Dedrick, R.L.1
Walicke, P.2
Garovoy, M.3
-
41
-
-
0026694672
-
The effect of anti-adhesion molecule antibody on the development of collagen-induced arthritis
-
KAKIMOTO K, NAKAMURA T, ISHII K et al.: The effect of anti-adhesion molecule antibody on the development of collagen-induced arthritis. Cell. Immunol. (1992) 142:326-337.
-
(1992)
Cell. Immunol.
, vol.142
, pp. 326-337
-
-
Kakimoto, K.1
Nakamura, T.2
Ishii, K.3
-
42
-
-
0028111883
-
Treatment of murine lupus with monoclonal antibodies to lymphocyte function-associated antigen-1: Dose-dependent inhibition of autoantibody production and blockade of the immune response to therapy
-
CONNOLLY MK, KITCHENS EA, CHAN B, JARDIEU P, WOFSY D: Treatment of murine lupus with monoclonal antibodies to lymphocyte function-associated antigen-1: dose-dependent inhibition of autoantibody production and blockade of the immune response to therapy. Clin. Immunol. Immunpathol. (1994) 72:198-203.
-
(1994)
Clin. Immunol. Immunpathol.
, vol.72
, pp. 198-203
-
-
Connolly, M.K.1
Kitchens, E.A.2
Chan, B.3
Jardieu, P.4
Wofsy, D.5
-
43
-
-
0027509516
-
Potent and effective prolongation by anti-LFA-1 monoclonal antibody monotherapy of non-primarily vascularized heart allograft survival in mice without T cell depletion
-
NAKAKURA EK, MCCABE SM, ZHENG B et al.: Potent and effective prolongation by anti-LFA-1 monoclonal antibody monotherapy of non-primarily vascularized heart allograft survival in mice without T cell depletion. Transplant. Proc. (1993) 55:412-417.
-
(1993)
Transplant. Proc.
, vol.55
, pp. 412-417
-
-
Nakakura, E.K.1
Mccabe, S.M.2
Zheng, B.3
-
44
-
-
0026579147
-
Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1
-
ISOBE M, YAGITA H, OKUMURA K, IHARA A: Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science (1992) 255:1125-1127.
-
(1992)
Science
, vol.255
, pp. 1125-1127
-
-
Isobe, M.1
Yagita, H.2
Okumura, K.3
Ihara, A.4
-
45
-
-
0029813191
-
Long-term survival of solid organ allografts by brief anti-lymphocyte function-associated antigen-1 monoclonal antibody monotherapy
-
NAKAKURA EK, SHORTHOUSE RA, ZHENG B, MCCABE SM, JARDIEU PM, MORRIS RE: Long-term survival of solid organ allografts by brief anti-lymphocyte function-associated antigen-1 monoclonal antibody monotherapy. Transplantation (1996) 62:547-552.
-
(1996)
Transplantation
, vol.62
, pp. 547-552
-
-
Nakakura, E.K.1
Shorthouse, R.A.2
Zheng, B.3
Mccabe, S.M.4
Jardieu, P.M.5
Morris, R.E.6
-
46
-
-
0034107978
-
Immune-adhesion molecules in the prevention of allograft rejection and reperfusion injury
-
BEHREND M: Immune-adhesion molecules in the prevention of allograft rejection and reperfusion injury. Ex. Opin. Investig. Drugs (2000) 9:789-805. A recent review of anti-adhesion therapies.
-
(2000)
Ex. Opin. Investig. Drugs
, vol.9
, pp. 789-805
-
-
Behrend, M.1
-
47
-
-
0025802034
-
Anti-LFA-1 monoclonal antibody (25.3) for treatment of steroid-resistant grade III-IV acute graft-versus-host disease
-
STOPPA AM, MARANINCHI D, BLAISE D et al.: Anti-LFA-1 monoclonal antibody (25.3) for treatment of steroid-resistant grade III-IV acute graft-versus-host disease. Transplant. Int. (1991) 4:3-7.
-
(1991)
Transplant. Int.
, vol.4
, pp. 3-7
-
-
Stoppa, A.M.1
Maraninchi, D.2
Blaise, D.3
-
48
-
-
0025973002
-
Reduction of graft failure by a monoclonal antibody (anti-LFA-1 CD11a) after HLA nonidentical bone marrow transplantation in children with immunodeficiencies, osteopetrosis, and Fanconi's anemia: A European group for immunodeficiency/European group for bone marrow transplantation report
-
FISCHER A, FRIEDRICH W, FASTH A et al.: Reduction of graft failure by a monoclonal antibody (anti-LFA-1 CD11a) after HLA nonidentical bone marrow transplantation in children with immunodeficiencies, osteopetrosis, and Fanconi's anemia: a European group for immunodeficiency/European group for bone marrow transplantation report. Blood (1991) 77:249-256.
-
(1991)
Blood
, vol.77
, pp. 249-256
-
-
Fischer, A.1
Friedrich, W.2
Fasth, A.3
-
49
-
-
9244225193
-
A Phase II trail of partially incompatible bone marrow transplantation for high-risk acute lymphoblastic leukaemia in children: Prevention of graft rejection with anti-LFA-1 and anti-CD2 antibodies
-
CAVAZZANA-CALVO MS, BORDIGONI P, MICHEL G: A Phase II trail of partially incompatible bone marrow transplantation for high-risk acute lymphoblastic leukaemia in children: prevention of graft rejection with anti-LFA-1 and anti-CD2 antibodies. Br. J. Haematol. (1996) 93:131-138.
-
(1996)
Br. J. Haematol.
, vol.93
, pp. 131-138
-
-
Cavazzana-Calvo, M.S.1
Bordigoni, P.2
Michel, G.3
-
50
-
-
0025916337
-
Effect of anti-LFA-1 (CD11a) monoclonal antibodies in acute rejection in human kidney transplantation
-
LE MAUFF B, HOURMANT M, ROUGIER J-P et al.: Effect of anti-LFA-1 (CD11a) monoclonal antibodies in acute rejection in human kidney transplantation. Transplantation (1991) 52:291-296.
-
(1991)
Transplantation
, vol.52
, pp. 291-296
-
-
Le Mauff, B.1
Hourmant, M.2
Rougier, J.-P.3
-
51
-
-
0030466367
-
A randomized multicenter trial comparing leukocyte function-associated antigen-1 monoclonal antibody with rabbit antithymocyte globulin as induction treatment in first kidney transplantations
-
HOURMANT M, BEDROSSIAN J, DURAND D et al.: A randomized multicenter trial comparing leukocyte function-associated antigen-1 monoclonal antibody with rabbit antithymocyte globulin as induction treatment in first kidney transplantations. Transplantation (1996) 62:1565-1570.
-
(1996)
Transplantation
, vol.62
, pp. 1565-1570
-
-
Hourmant, M.1
Bedrossian, J.2
Durand, D.3
-
52
-
-
0013203117
-
Prospective study of anti-CD11a antibody in prevention of delayed graft function (DGF) in recipients of highrisk renal cadaver grafts
-
May 2001
-
GABER AO: Prospective study of anti-CD11a antibody in prevention of delayed graft function (DGF) in recipients of highrisk renal cadaver grafts. Transplant 2001 Joint Meeting (2001) May 2001.
-
(2001)
Transplant 2001 Joint Meeting
-
-
Gaber, A.O.1
-
53
-
-
0024426267
-
In vivo infusion of anti LFA-1 antibody in HLA non-identical bone marrow transplantation in children: Serum concentrations and biological effects
-
PEREZ N, LE DEIST F, CHATENOUD L, CHANTELOUP N, GRISCELLI C, FISCHER A: In vivo infusion of anti LFA-1 antibody in HLA non-identical bone marrow transplantation in children: serum concentrations and biological effects. Bone Marrow Transplant. (1989) 4:379-384.
-
(1989)
Bone Marrow Transplant.
, vol.4
, pp. 379-384
-
-
Perez, N.1
Le Deist, F.2
Chatenoud, L.3
Chanteloup, N.4
Griscelli, C.5
Fischer, A.6
-
54
-
-
0030443253
-
Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1
-
WERTHER WA, GONZALEZ TN, O'CONNOR SJ et al.: Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1. J. Immunol. (1996) 157:4986-4995.
-
(1996)
J. Immunol.
, vol.157
, pp. 4986-4995
-
-
Werther, W.A.1
Gonzalez, T.N.2
O'Connor, S.J.3
-
55
-
-
0033044964
-
The pathogenesis of psoriasis: Immunological facts and speculations
-
BOS JD, DE RIE MA: The pathogenesis of psoriasis: immunological facts and speculations. Immunol. Today (1999) 20:40-46.
-
(1999)
Immunol. Today
, vol.20
, pp. 40-46
-
-
Bos, J.D.1
De Rie, M.A.2
-
56
-
-
0033506984
-
Population pharmacokinetics and pharmacodynamics of the anti-CD11a antibody hu1124 in human subjects with psoriasis
-
BAUER RJ, DEDRICK RL, WHITE ML, MURRAY MJ, GAROVOY MR: Population pharmacokinetics and pharmacodynamics of the anti-CD11a antibody hu1124 in human subjects with psoriasis. J. Pharmacokin. Biopharm. (1999) 27:397-420.
-
(1999)
J. Pharmacokin. Biopharm.
, vol.27
, pp. 397-420
-
-
Bauer, R.J.1
Dedrick, R.L.2
White, M.L.3
Murray, M.J.4
Garovoy, M.R.5
-
57
-
-
12944283147
-
Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis
-
GOTTLIEB A, KRUEGER JG, BRIGHT R et al.: Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis. J. Am. Acad. Dermatol. (2000) 42:428-435. An overview of the clinical effects of inhibiting CD11a function with efalizumab.
-
(2000)
J. Am. Acad. Dermatol.
, vol.42
, pp. 428-435
-
-
Gottlieb, A.1
Krueger, J.G.2
Bright, R.3
-
58
-
-
0036578664
-
Psoriasis as a model for T-cell-mediated disease: Immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a antibody
-
GOTTLIEB AB, KRUEGER JG, WITTKOWSKI K, DEDRICK RL, WALICKE PA, GAROVOY MR: Psoriasis as a model for T-cell-mediated disease: immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a antibody. Arch. Dermatol. (2002) 138:591-600.
-
(2002)
Arch. Dermatol.
, vol.138
, pp. 591-600
-
-
Gottlieb, A.B.1
Krueger, J.G.2
Wittkowski, K.3
Dedrick, R.L.4
Walicke, P.A.5
Garovoy, M.R.6
-
59
-
-
17944381053
-
The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody
-
PAPP K, BISSONNETTE R, KRUEGER JG et al.: The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody. J. Am. Acad. Dermatol. (2001) 45:665-674. Clinical results with efalizumab in a placebo-controlled psoriasis study.
-
(2001)
J. Am. Acad. Dermatol.
, vol.45
, pp. 665-674
-
-
Papp, K.1
Bissonnette, R.2
Krueger, J.G.3
-
60
-
-
0013197363
-
Continued treatment with efalizumab (anti-CD11a) improves outcome in patients with moderate to severe plaque psoriasis
-
LEBWOHL M, MILLER JL, GOLDMAN M et al.: Continued treatment with efalizumab (anti-CD11a) improves outcome in patients with moderate to severe plaque psoriasis. American Academy of Dermatology Annual Meeting 2002 (2002):216.
-
(2002)
American Academy of Dermatology Annual Meeting 2002
, pp. 216
-
-
Lebwohl, M.1
Miller, J.L.2
Goldman, M.3
-
62
-
-
0035378334
-
A key role for ICAM-1 in generating effector cells mediating inflammatory responses
-
CAMACHO SA, HEATH WR, CARBONE FR et al.: A key role for ICAM-1 in generating effector cells mediating inflammatory responses. Nat. Immunol. (2001) 2:523-529.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 523-529
-
-
Camacho, S.A.1
Heath, W.R.2
Carbone, F.R.3
-
63
-
-
0036604304
-
Stimulation through intercellular adhesion molecule-1 provides a second signal for T cell activation
-
CHIRATHAWORN C, KOHLMEIER JE, TIBBETTS SA, RUMSEY LA, CHAN MA, BENEDICT SH: Stimulation through intercellular adhesion molecule-1 provides a second signal for T cell activation. J. Immunol. (2002) 168:5530-5537.
-
(2002)
J. Immunol.
, vol.168
, pp. 5530-5537
-
-
Chirathaworn, C.1
Kohlmeier, J.E.2
Tibbetts, S.A.3
Rumsey, L.A.4
Chan, M.A.5
Benedict, S.H.6
-
64
-
-
0026348189
-
ICAM-1-dependent pathway is critically involved in the pathogenesis of adjuvant arthritis in rats
-
IIGO Y, TAKASHI T, TAMATANI T et al.: ICAM-1-dependent pathway is critically involved in the pathogenesis of adjuvant arthritis in rats. J. Immunol. (1991) 147:4167-4171.
-
(1991)
J. Immunol.
, vol.147
, pp. 4167-4171
-
-
Iigo, Y.1
Takashi, T.2
Tamatani, T.3
-
65
-
-
0025341115
-
In vivo effects of monoclonal antibody to ICAM-1 (CD54) in nonhuman primates with renal allografts
-
COSIMI AB, CONTI D, DELMONICO FL et al.: In vivo effects of monoclonal antibody to ICAM-1 (CD54) in nonhuman primates with renal allografts. J. Immunol. (1990) 144:4604-4612.
-
(1990)
J. Immunol.
, vol.144
, pp. 4604-4612
-
-
Cosimi, A.B.1
Conti, D.2
Delmonico, F.L.3
-
66
-
-
0027413809
-
A Phase I trial of immunosuppression with anti-ICAM-1 (CD54) mAb in renal allograft recipients
-
HAUG CE, COLVIN RB, DELMONICO FL et al.: A Phase I trial of immunosuppression with anti-ICAM-1 (CD54) mAb in renal allograft recipients. Transplantation (1993) 55:766-773.
-
(1993)
Transplantation
, vol.55
, pp. 766-773
-
-
Haug, C.E.1
Colvin, R.B.2
Delmonico, F.L.3
-
67
-
-
0028355977
-
Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1
-
KAVANAUGH AF, DAVIS LS, NICHOLS LA et al.: Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1. Arthritis Rheum. (1994) 37:992-999.
-
(1994)
Arthritis Rheum.
, vol.37
, pp. 992-999
-
-
Kavanaugh, A.F.1
Davis, L.S.2
Nichols, L.A.3
-
68
-
-
0033557749
-
Anti-ICAM-1 monoclonal antibody R6.5 (enlimomab) promotes activation of neutrophils in whole blood
-
VUORTE J, LINDSBERG PJ, KASTE M et al.: Anti-ICAM-1 monoclonal antibody R6.5 (enlimomab) promotes activation of neutrophils in whole blood. J. Immunol. (1999) 162:2353-2357.
-
(1999)
J. Immunol.
, vol.162
, pp. 2353-2357
-
-
Vuorte, J.1
Lindsberg, P.J.2
Kaste, M.3
-
69
-
-
0028220670
-
Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides
-
BENNETT CF, CONDON TP, GRIMM S, CHAN H, CHIANG M-Y: Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides. J. Immunol. (1994) 152:3530-3540.
-
(1994)
J. Immunol.
, vol.152
, pp. 3530-3540
-
-
Bennett, C.F.1
Condon, T.P.2
Grimm, S.3
Chan, H.4
Chiang, M.-Y.5
-
70
-
-
0027987972
-
Blocking of heart allograft rejection by intercellular adhesion molecule-1 antisense oligonucleotides alone or in combination with other immunosuppressive modalities
-
STEPKOWSKI SM, TU Y, CONDON TP, BENNETT CF: Blocking of heart allograft rejection by intercellular adhesion molecule-1 antisense oligonucleotides alone or in combination with other immunosuppressive modalities. J. Immunol. (1994) 153:5336-5346.
-
(1994)
J. Immunol.
, vol.153
, pp. 5336-5346
-
-
Stepkowski, S.M.1
Tu, Y.2
Condon, T.P.3
Bennett, C.F.4
-
71
-
-
0031782392
-
A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease
-
YACYSHYN BR, BOWEN-YACYSHYN MB, JEWELL L et al.: A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease. Gastroenterology (1998) 114:1133-1142.
-
(1998)
Gastroenterology
, vol.114
, pp. 1133-1142
-
-
Yacyshyn, B.R.1
Bowen-Yacyshyn, M.B.2
Jewell, L.3
-
72
-
-
0036198566
-
A randomized, placebo controlled trial of an antisense oligonucleotide to intracellular adhesion molecule-1 in the treatment of severe rheumatoid arthritis
-
MAKSYMOWYCH WP, BLACKBURN WD JR, TAMI JA, SHANAHAN WR: A randomized, placebo controlled trial of an antisense oligonucleotide to intracellular adhesion molecule-1 in the treatment of severe rheumatoid arthritis. J. Rheumatol. (2001) 29:447-453.
-
(2001)
J. Rheumatol.
, vol.29
, pp. 447-453
-
-
Maksymowych, W.P.1
Blackburn, W.D.J.R.2
Tami, J.A.3
Shanahan, W.R.4
-
73
-
-
0032170976
-
Phosphorothioate oligonucleotides inhibit intrinsic tenase complex
-
SHEEHAN JP, LAN H-C: Phosphorothioate oligonucleotides inhibit intrinsic tenase complex. Blood (1998) 92:1617-1625.
-
(1998)
Blood
, vol.92
, pp. 1617-1625
-
-
Sheehan, J.P.1
Lan, H.-C.2
-
74
-
-
0013198580
-
Isis announces disappointing results form ISIS 2302 clinical trial in Crohn's disease
-
December 15, 1999
-
ISIS PHARMACEUTICALS INC.: Isis announces disappointing results form ISIS 2302 clinical trial in Crohn's disease. Press Release (1999) December 15, 1999.
-
(1999)
Press Release
-
-
-
75
-
-
0025161990
-
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site
-
ELICES MJ, OSBORN L, TAKADA Y et al.: VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell (1990) 60:577-584.
-
(1990)
Cell
, vol.60
, pp. 577-584
-
-
Elices, M.J.1
Osborn, L.2
Takada, Y.3
-
76
-
-
0028044630
-
Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature
-
ELICES MJ, TSAI V, STRAHL D et al.: Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature. J. Clin. Invest. (1994) 93:405-416.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 405-416
-
-
Elices, M.J.1
Tsai, V.2
Strahl, D.3
-
77
-
-
0030988946
-
Expression of fibronectin splicing variants in organ transplantation: A differential pattern between rat cardiac allografts and isografts
-
COITO AJ, BROWN LF, PETERS JH, KUPIEC-WEGLINSKI JW: Expression of fibronectin splicing variants in organ transplantation: a differential pattern between rat cardiac allografts and isografts. Am. J. Pathol. (1997) 150:1757.
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 1757
-
-
Coito, A.J.1
Brown, L.F.2
Peters, J.H.3
Kupiec-Weglinski, J.W.4
-
79
-
-
0027529932
-
Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma
-
BARON JL, MADRI JA, RUDDLE NH, HASHIM G, JANEWAY CA JR.: Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma. J. Exp. Med. (1993) 177:57-68.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 57-68
-
-
Baron, J.L.1
Madri, J.A.2
Ruddle, N.H.3
Hashim, G.4
Janeway C.A., Jr.5
-
81
-
-
0028987311
-
A monoclonal antibody to α4 integrin suppresses and reverses active experimental allergic encephalomyelitis
-
KENT SJ, KARLIK SJ, CANNON C et al.: A monoclonal antibody to α4 integrin suppresses and reverses active experimental allergic encephalomyelitis. J. Neuroimmunol. (1995) 58:1-10.
-
(1995)
J. Neuroimmunol.
, vol.58
, pp. 1-10
-
-
Kent, S.J.1
Karlik, S.J.2
Cannon, C.3
-
82
-
-
0037080184
-
Beneficial effect of modified peptide inhibitor of α4 integrins on experimental allergic encephalomyelitis in Lewis rats
-
VAN DER LAAN LJW, VAN DER GOES A, WAUBEN MHM et al.: Beneficial effect of modified peptide inhibitor of α4 integrins on experimental allergic encephalomyelitis in Lewis rats. J. Neurosci. Res. (2002) 67:191-199.
-
(2002)
J. Neurosci. Res.
, vol.67
, pp. 191-199
-
-
Van Der Laan, L.J.W.1
Van Der Goes, A.2
Wauben, M.H.M.3
-
83
-
-
0026326328
-
T lymphocyte migration to arthritic joints and dermal inflammation in the rat: Differing migration patterns and the involvement of VLA-4
-
ISSEKUTZ TB, ISSEKUTZ AC: T lymphocyte migration to arthritic joints and dermal inflammation in the rat: differing migration patterns and the involvement of VLA-4. Clin. Immunol. Immunopathol. (1991) 61:436-447.
-
(1991)
Clin. Immunol. Immunopathol.
, vol.61
, pp. 436-447
-
-
Issekutz, T.B.1
Issekutz, A.C.2
-
84
-
-
0026343689
-
Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody: A likely role for VLA-4 in vivo
-
ISSEKUTZ TB: Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody: a likely role for VLA-4 in vivo. J. Immunol. (1991) 147:4178-4184.
-
(1991)
J. Immunol.
, vol.147
, pp. 4178-4184
-
-
Issekutz, T.B.1
-
86
-
-
0028072846
-
Immunosuppression to cardiac allografts and soluble antigens by anti-vascular cellular adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies
-
ISOBE M, SUZUKI J-I, YAGITA H et al.: Immunosuppression to cardiac allografts and soluble antigens by anti-vascular cellular adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies. J. Immunol. (1994) 153:5810-5818.
-
(1994)
J. Immunol.
, vol.153
, pp. 5810-5818
-
-
Isobe, M.1
Suzuki, J.-I.2
Yagita, H.3
-
87
-
-
0032520802
-
Blockade of very late antigen-4 integrin binding to fibronectin in allograft recipients: I. Treatment with connecting segment-1 peptides prevents acute rejection by suppressing intragraft mononuclear cell accumulation, endothelial activation, and cytokine expression
-
COITO AJ, KOROM S, GRASER E, VOLK H-D, VAN DE WATER L, KUPIEC-WEGLINSKI JW: Blockade of very late antigen-4 integrin binding to fibronectin in allograft recipients: I. treatment with connecting segment-1 peptides prevents acute rejection by suppressing intragraft mononuclear cell accumulation, endothelial activation, and cytokine expression. Transplantation (1998) 65:699-706.
-
(1998)
Transplantation
, vol.65
, pp. 699-706
-
-
Coito, A.J.1
Korom, S.2
Graser, E.3
Volk, H.-D.4
Van De Water, L.5
Kupiec-Weglinski, J.W.6
-
88
-
-
0035874624
-
α4 integrin in islet allograft rejection
-
STEGALL MD, DEAN PG, NINOVA D et al.: α4 integrin in islet allograft rejection. Transplantation (2001) 71:1549-1555.
-
(2001)
Transplantation
, vol.71
, pp. 1549-1555
-
-
Stegall, M.D.1
Dean, P.G.2
Ninova, D.3
-
89
-
-
0029826678
-
Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut homing integrin α4β7
-
HESTERBERG PE, WINSOR-HINES D, BRISKIN MJ et al.: Rapid resolution of chronic colitis in the cotton-top tamarin with an antibody to a gut homing integrin α4β7. Gastroenterology (1996) 111:1373-1380.
-
(1996)
Gastroenterology
, vol.111
, pp. 1373-1380
-
-
Hesterberg, P.E.1
Winsor-Hines, D.2
Briskin, M.J.3
-
90
-
-
0033546663
-
The effect of anti-α4 integrin antibody on brain lesion activity in MS
-
TUBRIDY N, BEHAN PO, CAPILDEO R et al.: The effect of anti-α4 integrin antibody on brain lesion activity in MS. Neurology (1999) 53:466-472.
-
(1999)
Neurology
, vol.53
, pp. 466-472
-
-
Tubridy, N.1
Behan, P.O.2
Capildeo, R.3
-
91
-
-
0034903450
-
A randomized placebo-controlled trial of a humanized monoclonal antibody to α4 integrin in active Crohn's disease
-
GORDON FH, LAI CWY, HAMILTON MI et al.: A randomized placebo-controlled trial of a humanized monoclonal antibody to α4 integrin in active Crohn's disease. Gastroenterology (2001) 121:268-274.
-
(2001)
Gastroenterology
, vol.121
, pp. 268-274
-
-
Gordon, F.H.1
Lai, C.W.Y.2
Hamilton, M.I.3
-
92
-
-
0036110371
-
A pilot study of treatment of active ulcerative colitis with natalizumab, a humanized monoclonal antibody to alpha-4 integrin
-
GORDON FH, HAMILTON MI, DONOGHUE S et al.: A pilot study of treatment of active ulcerative colitis with natalizumab, a humanized monoclonal antibody to alpha-4 integrin. Aliment. Pharmacol. Ther. (2002) 16:699-705.
-
(2002)
Aliment. Pharmacol. Ther.
, vol.16
, pp. 699-705
-
-
Gordon, F.H.1
Hamilton, M.I.2
Donoghue, S.3
-
93
-
-
0013198030
-
Elan and Biogen begin Phase III clinical trials of Antegren (natalizumab) in multiple sclerosis and Crohn's disease
-
December 18, 2001
-
ELAN CORPORATION: Elan and Biogen begin Phase III clinical trials of Antegren (natalizumab) in multiple sclerosis and Crohn's disease. Press Release (2001) December 18, 2001.
-
(2001)
Press Release
-
-
-
94
-
-
0000788815
-
An ascending dose trial of a humanized α4β7 antibody in ulcerative colitis (UC)
-
FEAGAN BG, MCDONALD J, GREENBERF G et al.: An ascending dose trial of a humanized α4β7 antibody in ulcerative colitis (UC). Gastroenterology (2000) 118A874.
-
(2000)
Gastroenterology
-
-
Feagan, B.G.1
Mcdonald, J.2
Greenberf, G.3
-
95
-
-
0027407109
-
Endothelial-leukocyte adhesion molecules
-
BEVILACQUA MP: Endothelial-leukocyte adhesion molecules. Ann. Rev. Immunol. (1993) 11:767-804.
-
(1993)
Ann. Rev. Immunol.
, vol.11
, pp. 767-804
-
-
Bevilacqua, M.P.1
-
96
-
-
0025942859
-
Analysis of T cell stimulation by superanngen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: Costimulation by purified adhesion ligands VCAM-1, ICAM-1 but not ELAM-1
-
VAN SEVENTER GA, NEWMAN W, SHIMIZU Y et al.: Analysis of T cell stimulation by superanngen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1 but not ELAM-1. J. Exp. Med. (1991) 174:901-913.
-
(1991)
J. Exp. Med.
, vol.174
, pp. 901-913
-
-
Van Seventer, G.A.1
Newman, W.2
Shimizu, Y.3
-
97
-
-
0028269225
-
-
LUKAS NW, STRIETER RW, EVANOFF HL, BURDICK MD, KUNKEL SL: VCAM-1 influences lymphocyte proliferation and cytokine production during mixed lymphocyte responses. (1994) 154:88-98.
-
(1994)
VCAM-1 Influences Lymphocyte Proliferation and Cytokine Production During Mixed Lymphocyte Responses
, vol.154
, pp. 88-98
-
-
Lukas, N.W.1
Strieter, R.W.2
Evanoff, H.L.3
Burdick, M.D.4
Kunkel, S.L.5
-
98
-
-
0036248519
-
Vascular cell adhesion molecule-1 (VCAM-1) blockade in collagen-induced arthritis reduces joint involvement and alters B cell trafficking
-
CARTER RA, CAMPBELL IK, O'DONNELL K, WICKS IP: Vascular cell adhesion molecule-1 (VCAM-1) blockade in collagen-induced arthritis reduces joint involvement and alters B cell trafficking. Clin. Exp. Immunol. (2002) 128:44-51.
-
(2002)
Clin. Exp. Immunol.
, vol.128
, pp. 44-51
-
-
Carter, R.A.1
Campbell, I.K.2
O'Donnell, K.3
Wicks, I.P.4
-
99
-
-
0033783628
-
VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice
-
SORIANO A, SALAS A, SALAS A et al.: VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice. Lab. Invest. (2000) 80:1541-1551. Inflammatory bowel disease is mediated by leukocyte trafficking to sites of inflammation rather than to the gut in general.
-
(2000)
Lab. Invest.
, vol.80
, pp. 1541-1551
-
-
Soriano, A.1
Salas, A.2
Salas, A.3
-
100
-
-
18244370299
-
Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule
-
GADEK TR, BURDICK DJ, MCDOWELL RS et al.: Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule. Science (2002) 295:1086-1089.
-
(2002)
Science
, vol.295
, pp. 1086-1089
-
-
Gadek, T.R.1
Burdick, D.J.2
Mcdowell, R.S.3
-
101
-
-
0032135083
-
Very late antigen 4 (VLA4) antagonists as anti-inflammatory agents
-
LIN K-C, CASTRO A: Very late antigen 4 (VLA4) antagonists as anti-inflammatory agents. Curr. Opin. Chem. Biol. (1998) 2:453-457.
-
(1998)
Curr. Opin. Chem. Biol.
, vol.2
, pp. 453-457
-
-
Lin, K.-C.1
Castro, A.2
-
102
-
-
0034948339
-
Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site
-
WEITZ-SCHMIDT G, WELZENBACH K, BRINKMANN V et al.: Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site. Nat. Med. (2001) 7:687-692.
-
(2001)
Nat. Med.
, vol.7
, pp. 687-692
-
-
Weitz-Schmidt, G.1
Welzenbach, K.2
Brinkmann, V.3
-
103
-
-
0034880897
-
A small-molecule antagonist of LFA-1 blocks a conformational change important for LFA-1 function
-
WOSKA JR JR., SHIH D-T, TAQUETI VR, HOGG N, KELLY TA, KISHIMOTO TK: A small-molecule antagonist of LFA-1 blocks a conformational change important for LFA-1 function. J. Leukoc. Biol. (2001) 70:329-334.
-
(2001)
J. Leukoc. Biol.
, vol.70
, pp. 329-334
-
-
Woska J.R., Jr.1
Shih, D.-T.2
Taqueti, V.R.3
Hogg, N.4
Kelly, T.A.5
Kishimoto, T.K.6
-
104
-
-
0036174736
-
Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases
-
YUSUF-MAKAGIANSAR H, ANDERSON ME, YAKOVLEVA TV, MURRAY JS, SIAHAAN TJ: Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases. Med. Res. Rev. (2002) 22:146-167.
-
(2002)
Med. Res. Rev.
, vol.22
, pp. 146-167
-
-
Yusuf-Makagiansar, H.1
Anderson, M.E.2
Yakovleva, T.V.3
Murray, J.S.4
Siahaan, T.J.5
|