CD4+ T cells migrate into inflamed skin only if they express ligands for E- and P-selectin

Journal of Immunology

Volumn 161, Issue 2, 1998, Pages 963-970

  Tietz, Wolfgang ^a   Allemand, Yvonne ^a   Borges, Eric ^b   Von Laer, Dorothea ^c   Hallmann, Ruppert ^d   Vestweber, Dietmar ^b   Hamann, Alf ^a,e  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; PADGEM PROTEIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL MIGRATION; DELAYED HYPERSENSITIVITY; DRUG RECEPTOR BINDING; GLYCOSYLATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT; SENSITIZATION; SKIN INFLAMMATION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; CYTOKINES; DERMATITIS, CONTACT; E-SELECTIN; FEMALE; IMMUNOPHENOTYPING; INTERPHASE; LIGANDS; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MICE; MICE, INBRED BALB C; P-SELECTIN; PROTEIN BINDING; SKIN; TH1 CELLS; TH2 CELLS;

EID: 0032528562     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Butcher, E. C. 1991. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67:1033.
2. Butcher, E. C., and L. J. Picker. 1996. Lymphocyte homing and homeostasis. Science 272:60.
3. Alon, R., H. Rossiter, X. Wang, T. A. Springer, and T. S. Kupper. 1994. Distinct cell surface ligands mediate T lymphocyte attachment and rolling on P and E selectin under physiological flow. J. Cell Biol. 127:1485.
4. Gallatin, W. M., I. L. Weissman, and E. C. Butcher. 1983. A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature 304:30.
5. + cells of memory phenotype. Eur. J. Immunol. 27:2225.
6. Cotran, R. S., M. A. Gimbrone, M. P. Bevilacqua, D. L. Mendrick, and J. S. Pober. 1986. Induction and detection of a human endothelial activation antigen in vivo. J. Exp. Med. 164:661.
7. McEver, R. P. 1990. Properties of GMP-140, an inducible granule membrane protein of platelets and endothelium. Blood Cells 16:80.
8. Moore, K. L., N. L. Stults, S. Diaz, D. F. Smith, R. D. Cummings, A. Varki, and R. P. McEver. 1992. Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells. J. Cell Biol. 118:445.
9. Sako, D., X. J. Chang, K. M. Barone, G. Vachino, H. M. White, G. Shaw, G. M., Veldman, K. M. Bean, T. J. Ahern, B. Furie, D. A. Cumming, and G. R. Larsen. 1993. Expression cloning of a functional glycoprotein ligand for P-selectin. Cell 75:1179.
10. Lenter, M., A. Levinovitz, S. Isenmann, and D. Vestweber. 1994. Monospecific and common glycoprotein ligands for E- and P-selectin on myeloid cells. J. Cell Biol. 125:471.
11. + T lymphocytes and regulates their production of proinflammatory cytokines. Eur. J. Immunol. 22:1789.
12. Kunzendorf, U., M. Notter, H. Hock, A. Distler, T. Diamantstein, and G. Walz. 1993. T cells bind to the endothelial adhesion molecule GMP-140 (P-selectin). Transplantation 56:1213.
13. Austrup, F., D. Vestweber, E. Borges, M. Löhning, R. Bräuer, U. Herz, H. Renz, R. Hallmann, A. Scheffold, A. Radbruch, and A. Hamann. 1997. P- and E-selectin mediate recruitment of T helper 1 but not T helper 2 cells into inflamed tissues. Nature 385:81.
14. Borges, E., W. Tietz, M. Steegmaier, T. Moll, R. Hallmann, A. Hamann, and D. Vestweber. 1997. P-Selectin glycoprotein ligand-1 (PSGL-1) on T helper 1 but not on T helper 2 cells binds to P-selectin and supports migration into inflamed skin. J. Exp. Med. 185:573.
15. Steegmaier, M., A. Levinovitz, S. Isenmann, E. Borges, M. Lenter, H. P. Kocher, B. Kleuser, and D. Vestweber. 1995. The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor. Nature 373:615.
16. Picker, L. J., S. A. Michie, L. S. Rott, and E. C. Butcher. 1990. A unique phenotype of skin-associated lymphocytes in humans: preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites. Am. J. Pathol. 136:1053.
17. Berg, E. L., T. Yoshino, L. S. Rott, M. K. Robinson, R. A. Warnock, T. K. Kishimoto, L. J. Picker, and E. C. Butcher. 1991. The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1. J. Exp. Med. 174:1461.
18. Fuhlbrigge, R. C., J. D. Kieffer, D. Armerding, and T. S. Kupper. 1997. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin homing T cells. Nature 389:978.
19. Mayadas, T. N., R. C. Johnson, H. Raybum, R. O. Hynes, and D. D. Wagner. 1993. Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell 74:541.
20. Labow, M. A., C. R. Norton, J. M. Rumberger, K. M. Lombard Gillooly, D. J. Shuster, J. Hubbard, R. Bertko, P. A. Knaack, R. W. Terry and M. L. Harbison. 1994. Characterization of E-selectin-deficient mice: demonstration of overlapping function of the endothelial selectins. Immunity 1:709.
21. Frenette, P. S., T. N. Mayadas, H. Rayburn, R. O. Hynes, and D. D. Wagner. 1996. Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins. Cell 84:563.
22. Ledbetter, J. A., and L. A. Herzenberg. 1979. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47:63.
23. Springer, T. A. 1980. Cell-surface differentiation in the mouse. In Monoclonal Antibodies. R. H. Kennett, T. J. McKearn, and K. B. Bechtol, eds. Plenum Press, New York, p. 186.
24. Hallmann, R., U. Zimmermann, L. M. Sorokin, L. Needham, and K. von der Mark. 1995. Adhesion of leukocytes to the inflamed endothelium. Scand. J. Rheumatol. 24 (Suppl. 101):107.
25. Bosse, R., and D. Vestweber. 1994. Only simultaneous blocking of the L- and P-selectin completely inhibits neutrophil migration into mouse peritoneum. Eur. J. Immunol. 24:3019.
26. Hamann, A., D. Jablonski-Westrich, A. Duijvestijn, E. C. Butcher, H. Baisch, R. Harder, and H.-G. Thiele. 1988. Evidence for an accessory role of LFA-1 in lymphocyte-high endothelium interaction during homing. J. Immunol. 140:693.
27. Hahne, M., U. Jager, S. Isenmann, R. Hallmann, and D. Vestweber. 1993. Five tumor necrosis factor-inducible cell adhesion mechanisms on the surface of mouse endothelioma cells mediate the binding of leukocytes. J. Cell Biol. 121: 655.
28. Assenmacher, M., J. A. Schmitz, and A. Radbruch. 1994. Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-y and in interleukin-4-expressing cells. Eur. J. Immunol. 24:1097.
29. 4-integrins in lymphocyte homing to mucosal tissues in vivo. J. Immunol. 152:3282.
30. Hamann, A., and P. Jonas. 1996. Lymphocyte migration in vivo: the mouse model. In Immunology Methods Manual. I. Lefkovits, ed. Academic Press, London, p. 1333.
31. Picker, L. J. 1993. Regulation of tissue-selective T-lymphocyte homing receptors during the virgin to memory/effector cell transition in human secondary lymphoid tissues. Am. Rev. Respir. Dis. 148:S47.
32. Picker, L. J., J. R. Treer, D. B. Ferguson, P. A. Collins, P. R. Bergstresser, and L. W. Terstappen. 1993. Control of lymphocyte recirculation in man. II. Differential regulation of the cutaneous lymphocyte-associated antigen, a tissue-selective homing receptor for skin-homing T cells. J. Immunol. 150: 1122.
33. + T cells repopulating scid mice with colitis. Eur. J. Immunol. In press.
34. - helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma. J. Exp. Med. 174:547.
35. Hamann, A., and S. Rebstock. 1993. Migration of activated lymphocytes. Curr. Top. Microbiol. Immunol. 184:109.