Blockade of very late antigen-4 integrin binding to fibronectin in allograft recipients: I. Treatment with connecting segment-1 peptides prevents acute rejection by suppressing intragraft mononuclear cell accumulation, endothelial activation, and cytokine expression

Transplantation

Volumn 65, Issue 5, 1998, Pages 699-706

  Coito, Ana J ^a,b   Korom, Stephan ^a   Graser, Elmara ^c   Volk, Hans Dieter ^c   Van De Water, Livingston ^d   Kupiec Weglinski, Jerzy W ^a,b,e  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HUMBOLDT UNIVERSITY   (Germany)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; BETA1 INTEGRIN; CD4 ANTIGEN; CD8 ANTIGEN; CELL ADHESION MOLECULE; FIBRONECTIN; GAMMA INTERFERON; INTEGRIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MESSENGER RNA; PEPTIDE; RECOMBINANT INTERLEUKIN 2; VASCULAR CELL ADHESION MOLECULE 1;

ALLOGRAFT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLONAL ANERGY; CONTROLLED STUDY; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNOHISTOCHEMISTRY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD3; BINDING SITES; BINDING, COMPETITIVE; CELL ADHESION MOLECULES; CYTOKINES; FIBRONECTINS; GRAFT REJECTION; HEART TRANSPLANTATION; IMMUNITY, CELLULAR; INTEGRIN ALPHA4BETA1; INTEGRINS; MALE; MOLECULAR SEQUENCE DATA; PEPTIDES; RATS; RATS, INBRED BN; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; RECEPTORS, LYMPHOCYTE HOMING; RNA, MESSENGER;

EID: 0032520802     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199803150-00017     Document Type: Article

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