-
1
-
-
0028281794
-
Association and activation of Jak-Tyk family by CNTF-LIF-OSM-IL-6β receptor components
-
Stahl, N., Boulton, T. G., Farruggella, T., Ip, N. Y., Davis, S., Witthuhn, B., Quelle, F., Silvennoinen, O., Barbieri, G., Pellegrini, S., Ihle, J. N., and Yancopoulos, G. D. 1994. Association and activation of Jak-Tyk family by CNTF-LIF-OSM-IL-6β receptor components. Science 263:92-95.
-
(1994)
Science
, vol.263
, pp. 92-95
-
-
Stahl, N.1
Boulton, T.G.2
Farruggella, T.3
Ip, N.Y.4
Davis, S.5
Witthuhn, B.6
Quelle, F.7
Silvennoinen, O.8
Barbieri, G.9
Pellegrini, S.10
Ihle, J.N.11
Yancopoulos, G.D.12
-
2
-
-
0028296179
-
Association of transcription factor APRF and protein kinase Jakl with the interleukin-6 signal transduction gp130
-
Lutticken, C., Wegenka, U. M., Yuan, J., Buschmann, J., Schindler, C., Ziemiecki, A., Harpur, A. G., Wilks, A. F., Yasukawa, K., Taga, T., Kishimoto, T., Barbieri, G., Pellegrini, S., Sendtner, M., Heinrich, P. C., and Horn, F. 1994. Association of transcription factor APRF and protein kinase Jakl with the interleukin-6 signal transduction gp130. Science 263:89-92.
-
(1994)
Science
, vol.263
, pp. 89-92
-
-
Lutticken, C.1
Wegenka, U.M.2
Yuan, J.3
Buschmann, J.4
Schindler, C.5
Ziemiecki, A.6
Harpur, A.G.7
Wilks, A.F.8
Yasukawa, K.9
Taga, T.10
Kishimoto, T.11
Barbieri, G.12
Pellegrini, S.13
Sendtner, M.14
Heinrich, P.C.15
Horn, F.16
-
3
-
-
0027496114
-
A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
-
Sadowski, H. B., Shuai, K., Darnell, J. E., Jr., and Gilman, M. Z. 1993. A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science 261:1739-1744.
-
(1993)
Science
, vol.261
, pp. 1739-1744
-
-
Sadowski, H.B.1
Shuai, K.2
Darnell J.E., Jr.3
Gilman, M.Z.4
-
4
-
-
0028349735
-
STAT3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
Zhong, Z., Wen, Z., and Darnell, J. E., Jr. 1994. STAT3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264:95-98.
-
(1994)
Science
, vol.264
, pp. 95-98
-
-
Zhong, Z.1
Wen, Z.2
Darnell J.E., Jr.3
-
5
-
-
0027772891
-
Polypeptide signaling to the nucleus through tyrosine phosphorylation of JAK and STAT proteins
-
Shuai, K., Ziemiecki, A., Wilks, A. F., Harpur, A. G., Sadowski, H. B., Gilman, M. Z., and Darnell, J. E. 1993. Polypeptide signaling to the nucleus through tyrosine phosphorylation of JAK and STAT proteins. Nature (London) 366:580-583.
-
(1993)
Nature (London)
, vol.366
, pp. 580-583
-
-
Shuai, K.1
Ziemiecki, A.2
Wilks, A.F.3
Harpur, A.G.4
Sadowski, H.B.5
Gilman, M.Z.6
Darnell, J.E.7
-
6
-
-
0030046753
-
STATs: Signal transducers and activators of transcription
-
Ihle, J. N. 1996. STATs: Signal transducers and activators of transcription. Cell 84:331-334.
-
(1996)
Cell
, vol.84
, pp. 331-334
-
-
Ihle, J.N.1
-
7
-
-
0031429943
-
Signaling mechanisms through gp130: A model of the cytokine system
-
Hirano, T., Nakajima, K., and Hibi, M. 1997. Signaling mechanisms through gp130: A model of the cytokine system. Cytokine Growth Factor Rev. 8:241-252.
-
(1997)
Cytokine Growth Factor Rev.
, vol.8
, pp. 241-252
-
-
Hirano, T.1
Nakajima, K.2
Hibi, M.3
-
8
-
-
0029923780
-
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 Waf1/CIP1 mediated by STAT1
-
Chin, Y. E., Kitagawa, M., Su, W. C., You, Z. H., Iwamoto, Y., and Fu, X. Y. 1996. Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 Waf1/CIP1 mediated by STAT1. Science 272:719-722.
-
(1996)
Science
, vol.272
, pp. 719-722
-
-
Chin, Y.E.1
Kitagawa, M.2
Su, W.C.3
You, Z.H.4
Iwamoto, Y.5
Fu, X.Y.6
-
9
-
-
0029967687
-
Differential activation of the extracellular signal-regulated kinase, Jun kinase and Janus kinase-Stat pathways by oncostatin M and basic fibroblast growth factor in AIDS-derived Kaposi's sarcoma cells
-
Faris, M., Ensoli, B., Stahl, N., Yancopoulos, G., Nguyen, A., Wang, S., and Nel, A. E. 1996. Differential activation of the extracellular signal-regulated kinase, Jun kinase and Janus kinase-Stat pathways by oncostatin M and basic fibroblast growth factor in AIDS-derived Kaposi's sarcoma cells. AIDS 10:369-378.
-
(1996)
AIDS
, vol.10
, pp. 369-378
-
-
Faris, M.1
Ensoli, B.2
Stahl, N.3
Yancopoulos, G.4
Nguyen, A.5
Wang, S.6
Nel, A.E.7
-
10
-
-
0029786754
-
Interferon-α-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase
-
Guazzi, M. C., Velasquez, L., McKendry, R., Mogensen, K. E., Fellous, M., and Pellegrini, S. 1996. Interferon-α-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase. J. Biol. Chem. 271:20494-20500.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20494-20500
-
-
Guazzi, M.C.1
Velasquez, L.2
McKendry, R.3
Mogensen, K.E.4
Fellous, M.5
Pellegrini, S.6
-
11
-
-
0030953469
-
Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop
-
Feng, J., Witthuhn, B. A., Matsuda, T., Kohlhuber, F., Kerr, I. M., and Ihle, J. N. 1997. Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop. Mol. Cell Biol. 17:2497-2501.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 2497-2501
-
-
Feng, J.1
Witthuhn, B.A.2
Matsuda, T.3
Kohlhuber, F.4
Kerr, I.M.5
Ihle, J.N.6
-
12
-
-
8044231313
-
An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT
-
Fujitani, Y., Hibi, M., Fukada, T., Takahashitezuka, M., Yoshida, H., Yamaguchi, T., Suiyama, K., Yamanaka, Y., Nakajima, K., and Hirano, T. 1997. An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT. Oncogene 14:751-761.
-
(1997)
Oncogene
, vol.14
, pp. 751-761
-
-
Fujitani, Y.1
Hibi, M.2
Fukada, T.3
Takahashitezuka, M.4
Yoshida, H.5
Yamaguchi, T.6
Suiyama, K.7
Yamanaka, Y.8
Nakajima, K.9
Hirano, T.10
-
13
-
-
0028097219
-
Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase
-
Frank, S. J., Gilliland, G., Kraft, A. S., and Arnold, C. S. 1994. Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase. Endocrinology 135:2228-2239.
-
(1994)
Endocrinology
, vol.135
, pp. 2228-2239
-
-
Frank, S.J.1
Gilliland, G.2
Kraft, A.S.3
Arnold, C.S.4
-
14
-
-
0031931647
-
Structural and mechanistic aspects of Janus kinases: How the two-faced god wields a double-edged sword
-
Duhè, R. J. and Farrar W. L. 1998. Structural and mechanistic aspects of Janus kinases: How the two-faced god wields a double-edged sword. J. Interferon Cytokine Res. 18:1-15.
-
(1998)
J. Interferon Cytokine Res.
, vol.18
, pp. 1-15
-
-
Duhè, R.J.1
Farrar, W.L.2
-
15
-
-
0028180569
-
JAK2 associates with the beta c chain of the receptor for granulocytemacrophage colony-stimulating factor, and its activation requires the membrane-proximal region
-
Quelle, F. W., Sato, N., Witthuhn, B. A., Inhorn, R. C., Eder, M., MiyaJima, A., Griffin, J. D., and Ihle, J. N. 1994. JAK2 associates with the beta c chain of the receptor for granulocytemacrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol. Cell Biol. 14:4335-4341.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 4335-4341
-
-
Quelle, F.W.1
Sato, N.2
Witthuhn, B.A.3
Inhorn, R.C.4
Eder, M.5
MiyaJima, A.6
Griffin, J.D.7
Ihle, J.N.8
-
16
-
-
0029009001
-
Separate signaling mechanisms are involved in the control of STAT protein activation and gene regulation via the interleukin 6 response element by the box 3 motif of gp130
-
Lai, C. F., Ripperger, J., Morella, K. K., Wang, Y., Gearing, D. P., Fey, G. H., and Baumann. H. 1995. Separate signaling mechanisms are involved in the control of STAT protein activation and gene regulation via the interleukin 6 response element by the box 3 motif of gp130. J. Biol. Chem. 270:14847-14850.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14847-14850
-
-
Lai, C.F.1
Ripperger, J.2
Morella, K.K.3
Wang, Y.4
Gearing, D.P.5
Fey, G.H.6
Baumann, H.7
-
17
-
-
0032076183
-
Disruption of the Jakl gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
-
Rodig, S., Meraz, M. A., White, J, M., Lampe, P. A., Riley, J. K., Arthur, C. D., King, K. L., Sheehan, K. C. F., Yin, L., Pennica, D., Johnson, E. M., Jr., and Schreiber, R. D. 1998. Disruption of the Jakl gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 93:373-383.
-
(1998)
Cell
, vol.93
, pp. 373-383
-
-
Rodig, S.1
Meraz, M.A.2
White, J.M.3
Lampe, P.A.4
Riley, J.K.5
Arthur, C.D.6
King, K.L.7
Sheehan, K.C.F.8
Yin, L.9
Pennica, D.10
Johnson E.M., Jr.11
Schreiber, R.D.12
-
18
-
-
18244432009
-
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
-
Neubauer, H., Cumano, A., Muller, M., Wu, H., Huffstadt, U., and Pfeffer, K. 1998. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell 93:397-409.
-
(1998)
Cell
, vol.93
, pp. 397-409
-
-
Neubauer, H.1
Cumano, A.2
Muller, M.3
Wu, H.4
Huffstadt, U.5
Pfeffer, K.6
-
19
-
-
0032076542
-
Jak 2 is essential for signaling through a variety of cytokine receptors
-
Parganas, E., Wang, D., Stravopodis, D., Topham, D. J., Marine, J. C., Teglund, S., Vanin, E., Bodner, S., Colomonici, O. R., van Deursen, J. M., Grosveld, G., and Ihle, J. N. 1998. Jak 2 is essential for signaling through a variety of cytokine receptors. Cell 93:385-395.
-
(1998)
Cell
, vol.93
, pp. 385-395
-
-
Parganas, E.1
Wang, D.2
Stravopodis, D.3
Topham, D.J.4
Marine, J.C.5
Teglund, S.6
Vanin, E.7
Bodner, S.8
Colomonici, O.R.9
Van Deursen, J.M.10
Grosveld, G.11
Ihle, J.N.12
-
20
-
-
0028799457
-
Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking JAK3
-
Thomis, D. C., Gurniak, C. B., Tivol, E., Sharpe, A. H., and Berg, L. J. 1995. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking JAK3. Science 270:794-797.
-
(1995)
Science
, vol.270
, pp. 794-797
-
-
Thomis, D.C.1
Gurniak, C.B.2
Tivol, E.3
Sharpe, A.H.4
Berg, L.J.5
-
21
-
-
0001514956
-
Identification of a Stat gene that function in Drosophila development
-
Yan, R., Small, S., Desplan, C., Dearolf, C. R., and Darnell, J. E. 1996. Identification of a Stat gene that function in Drosophila development. Cell 84:421-430.
-
(1996)
Cell
, vol.84
, pp. 421-430
-
-
Yan, R.1
Small, S.2
Desplan, C.3
Dearolf, C.R.4
Darnell, J.E.5
-
22
-
-
0033557744
-
Anopheles gambiae Ag-STAT, a new insect member of the STAT family, is activated in response to bacterial infection
-
Barillas-Mury, C., Han, Y.-S., Seely, D., and Kafatos, F. C. 1999. Anopheles gambiae Ag-STAT, a new insect member of the STAT family, is activated in response to bacterial infection. EMBO J. 18:959-967.
-
(1999)
EMBO J.
, vol.18
, pp. 959-967
-
-
Barillas-Mury, C.1
Han, Y.-S.2
Seely, D.3
Kafatos, F.C.4
-
23
-
-
0030935791
-
Antisense repression of protooncogene c-Cbl enhances activation of the JAK-STAT pathway but not the Ras pathway in epidermal growth factor receptor signalling
-
Ueno, H., Sasaki, K., Miyagawa, K., Honda, H., Mitani, K., Yazaki, Y., and Hirai, H. 1997. Antisense repression of protooncogene c-Cbl enhances activation of the JAK-STAT pathway but not the Ras pathway in epidermal growth factor receptor signalling. J. Biol. Chem. 272:8739-8743.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8739-8743
-
-
Ueno, H.1
Sasaki, K.2
Miyagawa, K.3
Honda, H.4
Mitani, K.5
Yazaki, Y.6
Hirai, H.7
-
24
-
-
0030807903
-
SH2 signaling in a lower eukaryote: A STAT protein that regulates stalk cell differentiation in Dictyostelium
-
Kawata, T., Shevchenko, A., Fukuzawa, M., Jermyn, K. A., Totty, N. F., Zhukovskaya, N. V., Sterling, A. E., Mann, M., and Williams, J. G. 1997. SH2 signaling in a lower eukaryote: a STAT protein that regulates stalk cell differentiation in Dictyostelium. Cell 89:909-916.
-
(1997)
Cell
, vol.89
, pp. 909-916
-
-
Kawata, T.1
Shevchenko, A.2
Fukuzawa, M.3
Jermyn, K.A.4
Totty, N.F.5
Zhukovskaya, N.V.6
Sterling, A.E.7
Mann, M.8
Williams, J.G.9
-
25
-
-
0029157421
-
Distribution of the mammalian Stat gene family in mouse chromosomes
-
Copeland, N. G., Gilbert, D. J., Schindler, C., Zhong, Z., Wen, Darnell, J. E., Jr., Mui, A. L., Miyajima, A., Quelle, F. W., Ihle, J. N., et al. 1995. Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics 29:225-228.
-
(1995)
Genomics
, vol.29
, pp. 225-228
-
-
Copeland, N.G.1
Gilbert, D.J.2
Schindler, C.3
Zhong, Z.4
Wen5
Darnell J.E., Jr.6
Mui, A.L.7
Miyajima, A.8
Quelle, F.W.9
Ihle, J.N.10
-
26
-
-
0029075875
-
Cooperative transcriptional activity of Jun and STAT3β, a short form of STAT3
-
Schaefer, T. S., Sanders, L. K., and Nathans, D. 1995. Cooperative transcriptional activity of Jun and STAT3β, a short form of STAT3. Proc. Natl. Acad. Sci. U.S.A. 92:9097.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 9097
-
-
Schaefer, T.S.1
Sanders, L.K.2
Nathans, D.3
-
27
-
-
0029666298
-
STAT3β, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription
-
Caldenhoven, E., van Dijk, T. B., Solari, R., Armstrong, J., Raaijmakers, J. A. M., Lammers, J. W. J., Koenderman, L., and de Groot, R. P. 1996. STAT3β, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription. J. Biol. Chem. 271:13221.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13221
-
-
Caldenhoven, E.1
Van Dijk, T.B.2
Solari, R.3
Armstrong, J.4
Raaijmakers, J.A.M.5
Lammers, J.W.J.6
Koenderman, L.7
De Groot, R.P.8
-
28
-
-
0031728894
-
Granulocyte colonystimulating factor activates a 72-kDa isoform of STAT3 in human neutrophils
-
Chakraborty, A. and Tweard, D. J. 1998. Granulocyte colonystimulating factor activates a 72-kDa isoform of STAT3 in human neutrophils. J. Leukoc. Biol. 64:675.
-
(1998)
J. Leukoc. Biol.
, vol.64
, pp. 675
-
-
Chakraborty, A.1
Tweard, D.J.2
-
29
-
-
0030611426
-
Functional differences between STAT3α and STAT3β
-
Schaefer, T. S., Sanders, L. K., Park, O. K., and Nathans, D. 1997. Functional differences between STAT3α and STAT3β. Mol. Cell Biol. 17:5307-5316.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 5307-5316
-
-
Schaefer, T.S.1
Sanders, L.K.2
Park, O.K.3
Nathans, D.4
-
30
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen, Z., Zhong, Z., and Darnell, J. E., Jr. 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell J.E., Jr.3
-
31
-
-
0032561211
-
Amino-terminal signal transducer and activator of transcription (STAT) domains regulate nuclear transloctation and STAT deactivation
-
Strehlow, I. and Schindler, C. 1998. Amino-terminal signal transducer and activator of transcription (STAT) domains regulate nuclear transloctation and STAT deactivation. J. Biol. Chem. 273:28049-28056.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28049-28056
-
-
Strehlow, I.1
Schindler, C.2
-
32
-
-
0032812761
-
Transcriptional regulation of the heat shock protein genes by STAT family transcription factors
-
Stephanou, A. and Latchman, D. S. 1999. Transcriptional regulation of the heat shock protein genes by STAT family transcription factors. Gene Expr. 7:311-319.
-
(1999)
Gene Expr.
, vol.7
, pp. 311-319
-
-
Stephanou, A.1
Latchman, D.S.2
-
33
-
-
0035831040
-
Arginine methylation of STAT1 modulates IFNα/β-induced transcription
-
Mowen, K. A., Tang, J., Zhu, W., Schurter, B. T., Shuai, K., Herschman, H. R., and David, M. 2001. Arginine methylation of STAT1 modulates IFNα/β-induced transcription. Cell 104: 731-741.
-
(2001)
Cell
, vol.104
, pp. 731-741
-
-
Mowen, K.A.1
Tang, J.2
Zhu, W.3
Schurter, B.T.4
Shuai, K.5
Herschman, H.R.6
David, M.7
-
34
-
-
0031740670
-
Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: Prevalence of latent STAT1 in high-molecular weight complexes
-
Lackmann, M., Harpur, A. G., Oates, A. C., Mann, R. J., Gabriel, A., Meutermans, W., Alewood, P. F., Kerr, I. M., Stark, G. R., and Wilks, A. F. 1998. Biomolecular interaction analysis of IFN gamma-induced signaling events in whole-cell lysates: Prevalence of latent STAT1 in high-molecular weight complexes. Growth Factors 16:39-51.
-
(1998)
Growth Factors
, vol.16
, pp. 39-51
-
-
Lackmann, M.1
Harpur, A.G.2
Oates, A.C.3
Mann, R.J.4
Gabriel, A.5
Meutermans, W.6
Alewood, P.F.7
Kerr, I.M.8
Stark, G.R.9
Wilks, A.F.10
-
35
-
-
0029767462
-
Cooperation of Stat2 and CBP/p300 in signaling induced by interferon α
-
Bhattacharya, S., Eckner, R., Grossman, S., Oldread, E., Arany, Z., D'Andrea, A., and Livingston, D. M. 1996. Cooperation of Stat2 and CBP/p300 in signaling induced by interferon α. Nature 383:344-347.
-
(1996)
Nature
, vol.383
, pp. 344-347
-
-
Bhattacharya, S.1
Eckner, R.2
Grossman, S.3
Oldread, E.4
Arany, Z.5
D'Andrea, A.6
Livingston, D.M.7
-
36
-
-
0030449174
-
Two contact regions between STAT1 and CBP/p300 in interferon gamma signaling
-
Zhang, J. J., Vinkemeier, U., Gu, W., Chakravarti, D., Horvath, C. M., and Darnell, J. E., Jr. 1996. Two contact regions between STAT1 and CBP/p300 in interferon gamma signaling. Proc. Natl. Acad. Sci. U.S.A. 93:15092-15096.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 15092-15096
-
-
Zhang, J.J.1
Vinkemeier, U.2
Gu, W.3
Chakravarti, D.4
Horvath, C.M.5
Darnell J.E., Jr.6
-
37
-
-
0033534562
-
Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling
-
Zhu, M., John, S., Berg, M., and Leonard, W. J. 1999. Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling. Cell 96:121-130.
-
(1999)
Cell
, vol.96
, pp. 121-130
-
-
Zhu, M.1
John, S.2
Berg, M.3
Leonard, W.J.4
-
38
-
-
0029557904
-
Stat1 depends on transcriptional synergy with Spl
-
Look, D. C., Pelletier, M. R., Tidwell, R. M., Roswit, W. T., and Holtzman, M. J. 1995. Stat1 depends on transcriptional synergy with Spl. J. Biol. Chem. 270:30264-30267.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 30264-30267
-
-
Look, D.C.1
Pelletier, M.R.2
Tidwell, R.M.3
Roswit, W.T.4
Holtzman, M.J.5
-
39
-
-
0030024563
-
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
-
Durbin, J. E., Hackenmiller, R., Simon, M. C., and Levy, D. E. 1996. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84:443-450.
-
(1996)
Cell
, vol.84
, pp. 443-450
-
-
Durbin, J.E.1
Hackenmiller, R.2
Simon, M.C.3
Levy, D.E.4
-
40
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK/STAT signal pathway
-
Meraz, M. A., White, J. M., Sheehan, K. C., Bach, E. A., Rodig, S. J., Dighe, A. S., Kaplan, D. H., Riley, J. K., Greenlund, A. C., Campbell, D., Carver-Moore, K., DuBois, R. N., Clark, R., Aguet, M., and Schreiber, R. D. 1996. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK/STAT signal pathway. Cell 84:431-442.
-
(1996)
Cell
, vol.84
, pp. 431-442
-
-
Meraz, M.A.1
White, J.M.2
Sheehan, K.C.3
Bach, E.A.4
Rodig, S.J.5
Dighe, A.S.6
Kaplan, D.H.7
Riley, J.K.8
Greenlund, A.C.9
Campbell, D.10
Carver-Moore, K.11
DuBois, R.N.12
Clark, R.13
Aguet, M.14
Schreiber, R.D.15
-
41
-
-
0034515268
-
Immune response in Stat2 knockout mice
-
Park, C., Li, S., Cha, E., and Schindler, C. 2000. Immune response in Stat2 knockout mice. Immunity 13:795-804.
-
(2000)
Immunity
, vol.13
, pp. 795-804
-
-
Park, C.1
Li, S.2
Cha, E.3
Schindler, C.4
-
42
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
Takeda, K., Noghuchi, K., Shi, W., Tanaka, T., Matsumoto, M., Yoshida, N., Kishimoto, T., and Akira, S. 1997. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc. Natl. Acad. Sci. U.S.A. 94:3801-3804.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 3801-3804
-
-
Takeda, K.1
Noghuchi, K.2
Shi, W.3
Tanaka, T.4
Matsumoto, M.5
Yoshida, N.6
Kishimoto, T.7
Akira, S.8
-
43
-
-
0029937270
-
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
-
Kaplan, M. H., Sun, Y.-L., Hoey, T., and Grusby, M. J. 1996. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382:171-174.
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Kaplan, M.H.1
Sun, Y.-L.2
Hoey, T.3
Grusby, M.J.4
-
44
-
-
15844396183
-
Requirement of Stat4 in interleukin-12 mediated responses of natural killer and T cells
-
Thierfelder, W. E., van Deursen, J. M., Yamamoto, K., Tripp, R. A., Sarawar, S. R., Carson, R. T., Sangster, M. Y., Vignali, D. A., Doherty, P. C., Grosveld, G. C., and Ihle, J. N. 1996. Requirement of Stat4 in interleukin-12 mediated responses of natural killer and T cells. Nature 382:171-174.
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Thierfelder, W.E.1
Van Deursen, J.M.2
Yamamoto, K.3
Tripp, R.A.4
Sarawar, S.R.5
Carson, R.T.6
Sangster, M.Y.7
Vignali, D.A.8
Doherty, P.C.9
Grosveld, G.C.10
Ihle, J.N.11
-
45
-
-
0031057929
-
Stat5a is mandatory for adult mammary gland development and lactogenesis
-
Liu, X., Robis Robinson, G. W., Wagner, K. U., Garrett, L., Wynshaw-Boris. A., and Hennighausen, L. 1997. Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev. 15:179-186.
-
(1997)
Genes Dev.
, vol.15
, pp. 179-186
-
-
Liu, X.1
Robis Robinson, G.W.2
Wagner, K.U.3
Garrett, L.4
Wynshaw-Boris, A.5
Hennighausen, L.6
-
46
-
-
0030833570
-
Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression
-
Udy, G. B., Towers, R. P., Snell, R. G., Wilkins, R. J., Park, S. H., Ram, P. A., Waxman, D. J., and Davey, H. W. 1997. Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression. Proc. Natl. Acad. Sci. U.S.A. 8:7239-7244.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.8
, pp. 7239-7244
-
-
Udy, G.B.1
Towers, R.P.2
Snell, R.G.3
Wilkins, R.J.4
Park, S.H.5
Ram, P.A.6
Waxman, D.J.7
Davey, H.W.8
-
47
-
-
0000943469
-
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
-
Teglund, S., McKay, C., Schuetz, E., van Deursen, J. M., Stravopodis, D., Wang, D., Brown, M., Bodner, S., Grosveld, G., and Ihle, J. N. 1998. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell 93:841-850.
-
(1998)
Cell
, vol.93
, pp. 841-850
-
-
Teglund, S.1
McKay, C.2
Schuetz, E.3
Van Deursen, J.M.4
Stravopodis, D.5
Wang, D.6
Brown, M.7
Bodner, S.8
Grosveld, G.9
Ihle, J.N.10
-
48
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
-
Kaplan, M. H., Schindler, U., Smiley, S. T., and Grusby, M. J. 1996. Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity 4:313-319.
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
49
-
-
0032479322
-
Colony-stimulating factor-1 stimulates the formation of multimeric cytosolic complexes of signaling proteins and cytoskeletal components in macrophages
-
Yeung, Y. G., Wang, Y., Einstein, D. B., Lee, P. S., and Stanley, E. R. 1998. Colony-stimulating factor-1 stimulates the formation of multimeric cytosolic complexes of signaling proteins and cytoskeletal components in macrophages. J. Biol. Chem. 3:17128-17137.
-
(1998)
J. Biol. Chem.
, vol.3
, pp. 17128-17137
-
-
Yeung, Y.G.1
Wang, Y.2
Einstein, D.B.3
Lee, P.S.4
Stanley, E.R.5
-
50
-
-
0033520313
-
Cellular physiology of STAT3: Where's the cytoplasmic monomer?
-
Ndubuisi, M. I., Guo, G. G., Fried, V. A., Etlinger, J. D., and Sehgal, P. B. 1999. Cellular physiology of STAT3: Where's the cytoplasmic monomer? J. Biol. Chem. 274:25499-25509.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25499-25509
-
-
Ndubuisi, M.I.1
Guo, G.G.2
Fried, V.A.3
Etlinger, J.D.4
Sehgal, P.B.5
-
51
-
-
0029972194
-
The rapid inactivation of nuclear tyrosine phosphorylated Statl depends upon a protein tyrosine phosphatase
-
Haspel, R. L., Salditt, G. M., and Darnell, J. E., Jr. 1996. The rapid inactivation of nuclear tyrosine phosphorylated Statl depends upon a protein tyrosine phosphatase. EMBO J. 22:6262- 6268.
-
(1996)
EMBO J.
, vol.22
, pp. 6262-6268
-
-
Haspel, R.L.1
Salditt, G.M.2
Darnell J.E., Jr.3
-
52
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
Taga, T. and Kishimoto, T. 1997. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15:797-819.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
53
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
Heinrich, P. C., Behrmann, I., Müller-Newen, G., Schaper, F., and Graeve, L. 1998. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J. 334:297-314.
-
(1998)
Biochem. J.
, vol.334
, pp. 297-314
-
-
Heinrich, P.C.1
Behrmann, I.2
Müller-Newen, G.3
Schaper, F.4
Graeve, L.5
-
54
-
-
0031859080
-
Regulation of IL-6 signaling by p53: STAT3- and STAT5-masking in p53-Val135-containing human hepatoma Hep3B cell lines
-
Rayanade, R. J., Ndubuisi, M. I., Etlinger, J. D., and Sehgal, P. B. 1998. Regulation of IL-6 signaling by p53: STAT3- and STAT5-masking in p53-Val135-containing human hepatoma Hep3B cell lines. J. Immunol. 161:325-334.
-
(1998)
J. Immunol.
, vol.161
, pp. 325-334
-
-
Rayanade, R.J.1
Ndubuisi, M.I.2
Etlinger, J.D.3
Sehgal, P.B.4
-
55
-
-
0029984570
-
Nucleocytoplasmic transport
-
Görlich, D. and Mattaj, I. W. 1996. Nucleocytoplasmic transport. Science 271:1513-1518.
-
(1996)
Science
, vol.271
, pp. 1513-1518
-
-
Görlich, D.1
Mattaj, I.W.2
-
56
-
-
0029851231
-
Functional interactions between Stat5 and the glucocorticoid receptor
-
Stocklin, E., Wissler, M., Gouilleux, F., and Groner, B. 1996. Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383:726-728.
-
(1996)
Nature
, vol.383
, pp. 726-728
-
-
Stocklin, E.1
Wissler, M.2
Gouilleux, F.3
Groner, B.4
-
57
-
-
0030667790
-
STAT3 acts as a co-activator of glucocorticoid receptor signaling
-
Zhang, Z. X., Jones, S., Hagood, J. S., Fuentes, N. L., and Fuller, G. M. 1997. STAT3 acts as a co-activator of glucocorticoid receptor signaling. J. Biol. Chem. 272:30607-30610.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30607-30610
-
-
Zhang, Z.X.1
Jones, S.2
Hagood, J.S.3
Fuentes, N.L.4
Fuller, G.M.5
-
58
-
-
0023441954
-
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor
-
Picard, D. and Yamamoto, K. 1987. Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor. EMBO J. 6:3333-3340.
-
(1987)
EMBO J.
, vol.6
, pp. 3333-3340
-
-
Picard, D.1
Yamamoto, K.2
-
59
-
-
0029958032
-
Interferon-gamma-dependent nuclear import of Stat1 is mediated by the GTPase activity of Ran/TC4
-
Sekimoto, T., Nakajima, K., Tachibana. T., Hirano, T., and Yoneda, Y. 1996. Interferon-gamma-dependent nuclear import of Stat1 is mediated by the GTPase activity of Ran/TC4. J. Biol. Chem. 271:31017-31020.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31017-31020
-
-
Sekimoto, T.1
Nakajima, K.2
Tachibana, T.3
Hirano, T.4
Yoneda, Y.5
-
60
-
-
0030670639
-
Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rchl
-
Sekimoto, T., Imamoto, N., Nakajima, K., Hirano, T., and Yoneda, Y. 1997. Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rchl. EMBO J. 16:7067-7077.
-
(1997)
EMBO J.
, vol.16
, pp. 7067-7077
-
-
Sekimoto, T.1
Imamoto, N.2
Nakajima, K.3
Hirano, T.4
Yoneda, Y.5
-
61
-
-
0033621066
-
A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1
-
Haspel, R. L. and Darnell, J. E., Jr. 1999. A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1. Procl. Natl. Acad. Sci. U.S.A. 966:10188-10193.
-
(1999)
Procl. Natl. Acad. Sci. U.S.A.
, vol.966
, pp. 10188-10193
-
-
Haspel, R.L.1
Darnell J.E., Jr.2
-
62
-
-
0034614626
-
Cytosolic tyrosine dephosphorylation of STAT5
-
Yu, C.-L., Jin, Y.-J., and Burakoff, S. J. 2000. Cytosolic tyrosine dephosphorylation of STAT5. J. Biol. Chem. 275:599-604.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 599-604
-
-
Yu, C.-L.1
Jin, Y.-J.2
Burakoff, S.J.3
-
63
-
-
13044259628
-
Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3
-
Woetmann, A., Nielsen, M., Christensen, S. T., Brockdorff, J., Kaltoft, K., Engel, A. M., Skov, S., Brender, C., Geisler, C., Svejgaard, A., Rygaard, J., Leick, V., and Odum, N. 1999. Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3. Proc. Natl. Acad. Sci. U.S.A. 96:10620-10625.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 10620-10625
-
-
Woetmann, A.1
Nielsen, M.2
Christensen, S.T.3
Brockdorff, J.4
Kaltoft, K.5
Engel, A.M.6
Skov, S.7
Brender, C.8
Geisler, C.9
Svejgaard, A.10
Rygaard, J.11
Leick, V.12
Odum, N.13
-
64
-
-
0029014206
-
A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
-
Yoshimura, A., Ohkubo, T., Kiguchi, T., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Hara, T., and Miyajima, A. 1995. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J. 14:2816-2826.
-
(1995)
EMBO J.
, vol.14
, pp. 2816-2826
-
-
Yoshimura, A.1
Ohkubo, T.2
Kiguchi, T.3
Jenkins, N.A.4
Gilbert, D.J.5
Copeland, N.G.6
Hara, T.7
Miyajima, A.8
-
65
-
-
0031758256
-
The CIS/JAB family: A novel negative regulators of JAK signalling pathways
-
Yoshimura, A. 1998. The CIS/JAB family: A novel negative regulators of JAK signalling pathways. Leukemia 12:1851-1857.
-
(1998)
Leukemia
, vol.12
, pp. 1851-1857
-
-
Yoshimura, A.1
-
66
-
-
0030839112
-
A new protein containing an SH2 domain that inhibits JAK kinases
-
Endo, T. A., Masuhara, M., Yocouchi, M., Suzuki, R., Sakamoto, H., Mitsui, K., Matsumoto, A., Tanimura, S., Ohtsubo, M., Misawa, H., Miyazaki, T., Leonor, N., Taniguchi, T., Fujita, T., Kanakura, Y., Komiya, S., and Yashimura, A. 1997. A new protein containing an SH2 domain that inhibits JAK kinases. Nature 387:921-924.
-
(1997)
Nature
, vol.387
, pp. 921-924
-
-
Endo, T.A.1
Masuhara, M.2
Yocouchi, M.3
Suzuki, R.4
Sakamoto, H.5
Mitsui, K.6
Matsumoto, A.7
Tanimura, S.8
Ohtsubo, M.9
Misawa, H.10
Miyazaki, T.11
Leonor, N.12
Taniguchi, T.13
Fujita, T.14
Kanakura, Y.15
Komiya, S.16
Yashimura, A.17
-
67
-
-
0030755934
-
Structure and function of a new STAT-induced STAT inhibitor
-
Naka, T., Narazaki, M., Hirata, M., Matsumoto, T., Minamoto, S., Aono, A., Nishimoto, N., Kajita, T., Taga, T., Yoshizaki, K., Akira, S., and Kishimoto, T. 1997. Structure and function of a new STAT-induced STAT inhibitor. Nature 387:924-929.
-
(1997)
Nature
, vol.387
, pp. 924-929
-
-
Naka, T.1
Narazaki, M.2
Hirata, M.3
Matsumoto, T.4
Minamoto, S.5
Aono, A.6
Nishimoto, N.7
Kajita, T.8
Taga, T.9
Yoshizaki, K.10
Akira, S.11
Kishimoto, T.12
-
68
-
-
0030725378
-
Specific inhibition of Stat3 signal transduction by PIAS3
-
Chung, C. D., Liao, J., Liu, B., Rao, X., Jay, P., Berta, P., and Shuai, K. 1997. Specific inhibition of Stat3 signal transduction by PIAS3. Science 278:1803-1805.
-
(1997)
Science
, vol.278
, pp. 1803-1805
-
-
Chung, C.D.1
Liao, J.2
Liu, B.3
Rao, X.4
Jay, P.5
Berta, P.6
Shuai, K.7
-
69
-
-
0032169599
-
Inhibition of Stat1-mediated gene activation by PIAS1
-
Liu, B., Liao, J., Rao, X., Kushner, S. A., Chung, C. D., Chang, D. D., and Shuai, K. 1998. Inhibition of Stat1-mediated gene activation by PIAS1. Proc. Natl. Acad. Sci. U.S.A. 95:10626-10631.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 10626-10631
-
-
Liu, B.1
Liao, J.2
Rao, X.3
Kushner, S.A.4
Chung, C.D.5
Chang, D.D.6
Shuai, K.7
-
70
-
-
0000413462
-
Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway
-
Kim, T. K. and Maniatis, T. 1996. Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway. Science 273:1717-1719.
-
(1996)
Science
, vol.273
, pp. 1717-1719
-
-
Kim, T.K.1
Maniatis, T.2
-
71
-
-
0027287428
-
Molecular cloning of the murine JAK1 protein tyrosine kinase and its expression in the mouse central nervous system
-
Yang, X., Chung, D., and Cepko, C. L. 1993. Molecular cloning of the murine JAK1 protein tyrosine kinase and its expression in the mouse central nervous system. J. Neurosci. 13:3006-3017.
-
(1993)
J. Neurosci.
, vol.13
, pp. 3006-3017
-
-
Yang, X.1
Chung, D.2
Cepko, C.L.3
-
72
-
-
0032211238
-
Members of the JAK/STAT proteins are expressed and regulated during development in the mammalian forebrain
-
De-Fraja, C., Conti, L., Magrassi, L., Govoni, S., and Cattaneo, E. 1998. Members of the JAK/STAT proteins are expressed and regulated during development in the mammalian forebrain. J. Neurosci. Res. 54:320-330.
-
(1998)
J. Neurosci. Res.
, vol.54
, pp. 320-330
-
-
De-Fraja, C.1
Conti, L.2
Magrassi, L.3
Govoni, S.4
Cattaneo, E.5
-
73
-
-
0032532614
-
Oligodendroglial survival factors, PDGF-AA and CNTF, activate similar JAK/STAT signaling pathways
-
Dell'Albani, P., Kahn, M. A., Cole, R., Condorelli, D. F., Giuffrida-Stella, A. M., and de Vellis, J. 1998. Oligodendroglial survival factors, PDGF-AA and CNTF, activate similar JAK/STAT signaling pathways. J. Neurosci. Res. 54:191-205.
-
(1998)
J. Neurosci. Res.
, vol.54
, pp. 191-205
-
-
Dell'Albani, P.1
Kahn, M.A.2
Cole, R.3
Condorelli, D.F.4
Giuffrida-Stella, A.M.5
De Vellis, J.6
-
74
-
-
0030708523
-
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway
-
Bonni, A., Sun, Y., Nadal-Vicens, M., Bhatt, A., Frank, D. A., Rozovsky, I., Stahl, N., Yancopoulus, G. D., and Greenberg, M. E. 1997. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science 278:477-483.
-
(1997)
Science
, vol.278
, pp. 477-483
-
-
Bonni, A.1
Sun, Y.2
Nadal-Vicens, M.3
Bhatt, A.4
Frank, D.A.5
Rozovsky, I.6
Stahl, N.7
Yancopoulus, G.D.8
Greenberg, M.E.9
-
75
-
-
0035071413
-
Selective introduction of antisense oligonucleotides into single adult CNS progenitor cell using electroporation demonstrates the requirement of STAT3 activation for CNTF-induced gliogenesis
-
Aberg, M. A. I., Ryttsen, F., Hellgren, G., Lindell, K., Rosengren, L. E., MacLennan, J., Carlsson, B., Orwar, O., and Eriksson, P. S. 2001. Selective introduction of antisense oligonucleotides into single adult CNS progenitor cell using electroporation demonstrates the requirement of STAT3 activation for CNTF-induced gliogenesis. Mol. Cell Neurosci. 17:426-443.
-
(2001)
Mol. Cell Neurosci.
, vol.17
, pp. 426-443
-
-
Aberg, M.A.I.1
Ryttsen, F.2
Hellgren, G.3
Lindell, K.4
Rosengren, L.E.5
MacLennan, J.6
Carlsson, B.7
Orwar, O.8
Eriksson, P.S.9
-
76
-
-
0031001345
-
Ciliary neurotrophic factor activates JAK/Stat signal transduction cascade and induces transcriptional expression of glial fibrillary acidic protein in glial cells
-
Kahn, M. A., Huang, C. J., Caruso, A., Barresi, V., Nazarian, R., Condorelli, D. F., and de Vellis, J. 1997. Ciliary neurotrophic factor activates JAK/Stat signal transduction cascade and induces transcriptional expression of glial fibrillary acidic protein in glial cells. J. Neurochem. 68:1413-1423.
-
(1997)
J. Neurochem.
, vol.68
, pp. 1413-1423
-
-
Kahn, M.A.1
Huang, C.J.2
Caruso, A.3
Barresi, V.4
Nazarian, R.5
Condorelli, D.F.6
De Vellis, J.7
-
77
-
-
0033151937
-
Signal transduction pathways induced by GM-CSF in microglia: Significance in the control of proliferation
-
Liva, S. M., Kahn, M. A., Dopp, J. M., and de Vellis, J. 1999. Signal transduction pathways induced by GM-CSF in microglia: Significance in the control of proliferation. Glia. 26:344-352.
-
(1999)
Glia
, vol.26
, pp. 344-352
-
-
Liva, S.M.1
Kahn, M.A.2
Dopp, J.M.3
De Vellis, J.4
-
78
-
-
0026463554
-
Nitric oxide-mediate neuronal injury in multiple sclerosis
-
Sherman, M. P., Griscavage, J. M., and Ignarro, L. J. 1992. Nitric oxide-mediate neuronal injury in multiple sclerosis. Med. Hypotheses 39:143-146.
-
(1992)
Med. Hypotheses
, vol.39
, pp. 143-146
-
-
Sherman, M.P.1
Griscavage, J.M.2
Ignarro, L.J.3
-
79
-
-
0028609847
-
Oxygen free radicals and neurodegeneration in Parkinson's disease a role for nitric oxide
-
Youdim, M. B., Lavie, L., and Riederer, P. 1994. Oxygen free radicals and neurodegeneration in Parkinson's disease a role for nitric oxide. Ann. N. Y. Acad. Sci. 738:64-68.
-
(1994)
Ann. N. Y. Acad. Sci.
, vol.738
, pp. 64-68
-
-
Youdim, M.B.1
Lavie, L.2
Riederer, P.3
-
80
-
-
0029910556
-
Nitric oxide-mediated mitochondrial damage: A potential neuroprotective role for glutathione
-
Bolanos, P. J., Heales, S. J. R., Peuchen, S., Barker, J. E., Land, J. M., and Clark, J. B. 1996. Nitric oxide-mediated mitochondrial damage: A potential neuroprotective role for glutathione. Free Rad. Biol. Med. 21:995-1001.
-
(1996)
Free Rad. Biol. Med.
, vol.21
, pp. 995-1001
-
-
Bolanos, P.J.1
Heales, S.J.R.2
Peuchen, S.3
Barker, J.E.4
Land, J.M.5
Clark, J.B.6
-
81
-
-
0032179726
-
Effect of nitric oxide synthase induction on the expression of mitochondrial respiratory chain enzyme subunits in mixed cortical and astroglial cell cultures
-
Nicoletti, V. G., Caruso, A., Tendi, E. A., Privitera, A., Console, A., Calabrese, V., Spadaro, F., Ravagna, A., Copani, A., and Giuffrida-Stella, A. M. 1998. Effect of nitric oxide synthase induction on the expression of mitochondrial respiratory chain enzyme subunits in mixed cortical and astroglial cell cultures. Biochimie 80:871-881.
-
(1998)
Biochimie
, vol.80
, pp. 871-881
-
-
Nicoletti, V.G.1
Caruso, A.2
Tendi, E.A.3
Privitera, A.4
Console, A.5
Calabrese, V.6
Spadaro, F.7
Ravagna, A.8
Copani, A.9
Giuffrida-Stella, A.M.10
-
82
-
-
0026486613
-
Induction of calcium-independent nitric oxide synthetase activity in primary rat glial cultures
-
Galea, E., Feinstein, D. L., and Reis, D. J. 1992. Induction of calcium-independent nitric oxide synthetase activity in primary rat glial cultures. Proc. Natl. Acad. Sci. U.S.A. 89:10945-10949.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 10945-10949
-
-
Galea, E.1
Feinstein, D.L.2
Reis, D.J.3
-
83
-
-
0026774797
-
Induction of nitric oxide synthase in glial cells
-
Simmons, M. L. and Murphy, S. 1992. Induction of nitric oxide synthase in glial cells. J. Neurochem. 59:897-905.
-
(1992)
J. Neurochem.
, vol.59
, pp. 897-905
-
-
Simmons, M.L.1
Murphy, S.2
-
84
-
-
0035449872
-
JAK/STAT signaling pathway mediates cytokine-induced iNOS expression in primary astroglial cell cultures
-
Dell'Albani, P., Santangelo, R., Torrisi, L., Nicoletti, V. G., de Vellis, J., and Giuffrida Stella, A. M. 2001. JAK/STAT signaling pathway mediates cytokine-induced iNOS expression in primary astroglial cell cultures. J. Neurosci. Res. 65:417-424.
-
(2001)
J. Neurosci. Res.
, vol.65
, pp. 417-424
-
-
Dell'Albani, P.1
Santangelo, R.2
Torrisi, L.3
Nicoletti, V.G.4
De Vellis, J.5
Giuffrida Stella, A.M.6
-
85
-
-
0027400726
-
Multiple defects of immune cell function in mice with disrupted interferon-gamma genes
-
Dalton, D. K., Pitts-Meek, S., Keshav, S., Figari, I. S., Bradley, A., and Stewart, T. A. 1993. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science 259:1739-1742.
-
(1993)
Science
, vol.259
, pp. 1739-1742
-
-
Dalton, D.K.1
Pitts-Meek, S.2
Keshav, S.3
Figari, I.S.4
Bradley, A.5
Stewart, T.A.6
-
86
-
-
0027267486
-
Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor
-
Kamijo, R., Shapiro, D., Le, J., Huang, S., Aguet, M., and Vilcek, J. 1993. Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor. Procl. Natl. Acad. Sci. U.S.A. 90:6626-6630.
-
(1993)
Procl. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 6626-6630
-
-
Kamijo, R.1
Shapiro, D.2
Le, J.3
Huang, S.4
Aguet, M.5
Vilcek, J.6
-
87
-
-
0034237617
-
STAT signalling in the mature and aging brain
-
De-Fraja, C., Conti, L., Magrassi, L., Govoni, S., Battaini, F., and Cattaneo, E. 2000. STAT signalling in the mature and aging brain. Int. J. Devl. Neurosci. 18:439-446.
-
(2000)
Int. J. Devl. Neurosci.
, vol.18
, pp. 439-446
-
-
De-Fraja, C.1
Conti, L.2
Magrassi, L.3
Govoni, S.4
Battaini, F.5
Cattaneo, E.6
-
88
-
-
0031864202
-
Variations in the level of the JAK/STAT and ShcA proteins in human brain tumors
-
Cattaneo, E., Magrassi, L., De-Fraja, C., Conti, L., Di Gennaro, I., Butti, G., and Covoni, S. 1998. Variations in the level of the JAK/STAT and ShcA proteins in human brain tumors. Anticancer Res. 18:2381-2388.
-
(1998)
Anticancer Res.
, vol.18
, pp. 2381-2388
-
-
Cattaneo, E.1
Magrassi, L.2
De-Fraja, C.3
Conti, L.4
Di Gennaro, I.5
Butti, G.6
Covoni, S.7
-
89
-
-
0032782375
-
Expression of the JAKs and STATs superfamilies in human meningiomas
-
Magrassi, L., De-Fraja, C., Conti, L., Pezzotta, S., Butti, G., Covoni, S., and Cattaneo, E. 1999. Expression of the JAKs and STATs superfamilies in human meningiomas. J. Neurosurgery 91:440-446.
-
(1999)
J. Neurosurgery
, vol.91
, pp. 440-446
-
-
Magrassi, L.1
De-Fraja, C.2
Conti, L.3
Pezzotta, S.4
Butti, G.5
Covoni, S.6
Cattaneo, E.7
-
90
-
-
0030466918
-
Induction of Stat3, a signal transducer and trascription factor, in reactive microglia following transient focal cerebral ischaemia
-
Planas, A. M., Soriano, M. A., Berruezo, M., Justicia, C., Estrada, A., Pitarch, S., and Ferrer, I. 1996. Induction of Stat3, a signal transducer and trascription factor, in reactive microglia following transient focal cerebral ischaemia. Eur. J. Neurosci. 8:2612-2618.
-
(1996)
Eur. J. Neurosci.
, vol.8
, pp. 2612-2618
-
-
Planas, A.M.1
Soriano, M.A.2
Berruezo, M.3
Justicia, C.4
Estrada, A.5
Pitarch, S.6
Ferrer, I.7
-
91
-
-
0027318190
-
Bcl-2 inhibits death of central neural cells induced by multiple agents
-
Zhong, L., Sarafian, T., Kane, D. J., Charles, A. C., Mah, S. P., Edwards, R. H., and Bredesen, D. E. 1993. Bcl-2 inhibits death of central neural cells induced by multiple agents. Proc. Natl. Acad. Sci. U.S.A. 90:4533-4537.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 4533-4537
-
-
Zhong, L.1
Sarafian, T.2
Kane, D.J.3
Charles, A.C.4
Mah, S.P.5
Edwards, R.H.6
Bredesen, D.E.7
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