메뉴 건너뛰기




Volumn 273, Issue 5282, 1996, Pages 1717-1719

Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; PROTEASOME; UBIQUITIN;

EID: 0000413462     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.273.5282.1717     Document Type: Article
Times cited : (364)

References (30)
  • 1
    • 0028234529 scopus 로고
    • J. E. Darnell Jr., I. M. Kerr, G. R. Stark, Science 264, 1415 (1994); J. N. Ihle, Nature 377, 591 (1995); T. Taniguchi, Science 268, 251 (1995).
    • (1994) Science , vol.264 , pp. 1415
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 2
    • 0028845212 scopus 로고
    • J. E. Darnell Jr., I. M. Kerr, G. R. Stark, Science 264, 1415 (1994); J. N. Ihle, Nature 377, 591 (1995); T. Taniguchi, Science 268, 251 (1995).
    • (1995) Nature , vol.377 , pp. 591
    • Ihle, J.N.1
  • 3
    • 0028964465 scopus 로고
    • J. E. Darnell Jr., I. M. Kerr, G. R. Stark, Science 264, 1415 (1994); J. N. Ihle, Nature 377, 591 (1995); T. Taniguchi, Science 268, 251 (1995).
    • (1995) Science , vol.268 , pp. 251
    • Taniguchi, T.1
  • 7
    • 0027980321 scopus 로고    scopus 로고
    • V. J. Palombella, O. J. Rando, A. L. Goldberg, T. Maniatis, Cell 78, 773 (1994); K. L. Rock et al., ibid., p. 761.
    • Cell , pp. 761
    • Rock, K.L.1
  • 8
    • 0001650076 scopus 로고
    • S. Jentsch, Annu. Rev. Genet. 26, 177 (1992); A. Hersko and A. Ciechanover, Annu. Rev. Biochem. 61, 761 (1992); A. Ciechanover, Cell 79, 13 (1994); M. Hochstrasser, Curr. Opin. Cell Biol. 7, 215 (1995); A. W. Murray, Cell 81, 149 (1995); A. L. Goldberg, Science 268, 522 (1995); R. J. Deshaies, Trends Cell Biol. 5, 428 (1995).
    • (1992) Annu. Rev. Genet. , vol.26 , pp. 177
    • Jentsch, S.1
  • 9
    • 0026663539 scopus 로고
    • S. Jentsch, Annu. Rev. Genet. 26, 177 (1992); A. Hersko and A. Ciechanover, Annu. Rev. Biochem. 61, 761 (1992); A. Ciechanover, Cell 79, 13 (1994); M. Hochstrasser, Curr. Opin. Cell Biol. 7, 215 (1995); A. W. Murray, Cell 81, 149 (1995); A. L. Goldberg, Science 268, 522 (1995); R. J. Deshaies, Trends Cell Biol. 5, 428 (1995).
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 761
    • Hersko, A.1    Ciechanover, A.2
  • 10
    • 0028018268 scopus 로고
    • S. Jentsch, Annu. Rev. Genet. 26, 177 (1992); A. Hersko and A. Ciechanover, Annu. Rev. Biochem. 61, 761 (1992); A. Ciechanover, Cell 79, 13 (1994); M. Hochstrasser, Curr. Opin. Cell Biol. 7, 215 (1995); A. W. Murray, Cell 81, 149 (1995); A. L. Goldberg, Science 268, 522 (1995); R. J. Deshaies, Trends Cell Biol. 5, 428 (1995).
    • (1994) Cell , vol.79 , pp. 13
    • Ciechanover, A.1
  • 11
    • 0028935165 scopus 로고
    • S. Jentsch, Annu. Rev. Genet. 26, 177 (1992); A. Hersko and A. Ciechanover, Annu. Rev. Biochem. 61, 761 (1992); A. Ciechanover, Cell 79, 13 (1994); M. Hochstrasser, Curr. Opin. Cell Biol. 7, 215 (1995); A. W. Murray, Cell 81, 149 (1995); A. L. Goldberg, Science 268, 522 (1995); R. J. Deshaies, Trends Cell Biol. 5, 428 (1995).
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 215
    • Hochstrasser, M.1
  • 12
    • 0029051233 scopus 로고
    • S. Jentsch, Annu. Rev. Genet. 26, 177 (1992); A. Hersko and A. Ciechanover, Annu. Rev. Biochem. 61, 761 (1992); A. Ciechanover, Cell 79, 13 (1994); M. Hochstrasser, Curr. Opin. Cell Biol. 7, 215 (1995); A. W. Murray, Cell 81, 149 (1995); A. L. Goldberg, Science 268, 522 (1995); R. J. Deshaies, Trends Cell Biol. 5, 428 (1995).
    • (1995) Cell , vol.81 , pp. 149
    • Murray, A.W.1
  • 13
    • 0029071646 scopus 로고
    • S. Jentsch, Annu. Rev. Genet. 26, 177 (1992); A. Hersko and A. Ciechanover, Annu. Rev. Biochem. 61, 761 (1992); A. Ciechanover, Cell 79, 13 (1994); M. Hochstrasser, Curr. Opin. Cell Biol. 7, 215 (1995); A. W. Murray, Cell 81, 149 (1995); A. L. Goldberg, Science 268, 522 (1995); R. J. Deshaies, Trends Cell Biol. 5, 428 (1995).
    • (1995) Science , vol.268 , pp. 522
    • Goldberg, A.L.1
  • 14
    • 0028841492 scopus 로고
    • S. Jentsch, Annu. Rev. Genet. 26, 177 (1992); A. Hersko and A. Ciechanover, Annu. Rev. Biochem. 61, 761 (1992); A. Ciechanover, Cell 79, 13 (1994); M. Hochstrasser, Curr. Opin. Cell Biol. 7, 215 (1995); A. W. Murray, Cell 81, 149 (1995); A. L. Goldberg, Science 268, 522 (1995); R. J. Deshaies, Trends Cell Biol. 5, 428 (1995).
    • (1995) Trends Cell Biol. , vol.5 , pp. 428
    • Deshaies, R.J.1
  • 16
    • 10144257977 scopus 로고    scopus 로고
    • note
    • Cells were lysed in a buffer containing 6 M guanidinium hydrochloride, and ubiquitin-conjugated proteins were purified by nickel chromatography under the denatured condition. These denatured conditions significantly inhibit the deubiquitination activities. Otherwise, it is difficult to detect multi-ubiquitinated proteins because of potent isopeptidase activities that hydrolyze multi-ubiquitin chains.
  • 18
    • 0029146930 scopus 로고
    • Z. Chen et al., Genes Dev. 9, 1586 (1995). The extracts were prepared in the presence of SDS (0.1%) and N-ethylmaleimide (5 mM) to inhibit potent isopeptidase activities that may affect the detection of multi-ubiquitinated proteins.
    • (1995) Genes Dev. , vol.9 , pp. 1586
    • Chen, Z.1
  • 20
    • 0029117304 scopus 로고
    • K. Shuai, G. R. Stark, I. M. Kerr, J. E. Damell Jr., Science 261, 1744 (1993); Z. Wen, Z. Zhong, J. E. Darnell Jr., Cell 82, 241 (1995).
    • (1995) Cell , vol.82 , pp. 241
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 21
    • 0027434082 scopus 로고
    • M. Muller et al., EMBO J. 12, 4221 (1993).
    • (1993) EMBO J. , vol.12 , pp. 4221
    • Muller, M.1
  • 22
    • 0026509543 scopus 로고
    • M. Tyers, G. Tokiwa, R. Nash, B. Futcher, ibid. 11, 1773 (1992); S. R. Salma, K. B. Hendricks, J. Thorner, Mol. Cell. Biol. 14, 7953 (1994); R. J. Deshaies, V. Chau, M. Kirschner, EMBO J. 14, 303 (1995); J. Yaglom et al., Mol. Cell. Biol. 15, 731 (1995).
    • (1992) EMBO J. , vol.11 , pp. 1773
    • Tyers, M.1    Tokiwa, G.2    Nash, R.3    Futcher, B.4
  • 23
    • 0028171039 scopus 로고
    • M. Tyers, G. Tokiwa, R. Nash, B. Futcher, ibid. 11, 1773 (1992); S. R. Salma, K. B. Hendricks, J. Thorner, Mol. Cell. Biol. 14, 7953 (1994); R. J. Deshaies, V. Chau, M. Kirschner, EMBO J. 14, 303 (1995); J. Yaglom et al., Mol. Cell. Biol. 15, 731 (1995).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7953
    • Salma, S.R.1    Hendricks, K.B.2    Thorner, J.3
  • 24
    • 0028985013 scopus 로고
    • M. Tyers, G. Tokiwa, R. Nash, B. Futcher, ibid. 11, 1773 (1992); S. R. Salma, K. B. Hendricks, J. Thorner, Mol. Cell. Biol. 14, 7953 (1994); R. J. Deshaies, V. Chau, M. Kirschner, EMBO J. 14, 303 (1995); J. Yaglom et al., Mol. Cell. Biol. 15, 731 (1995).
    • (1995) EMBO J. , vol.14 , pp. 303
    • Deshaies, R.J.1    Chau, V.2    Kirschner, M.3
  • 25
    • 0028983369 scopus 로고
    • M. Tyers, G. Tokiwa, R. Nash, B. Futcher, ibid. 11, 1773 (1992); S. R. Salma, K. B. Hendricks, J. Thorner, Mol. Cell. Biol. 14, 7953 (1994); R. J. Deshaies, V. Chau, M. Kirschner, EMBO J. 14, 303 (1995); J. Yaglom et al., Mol. Cell. Biol. 15, 731 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 731
    • Yaglom, J.1
  • 27
    • 0028986075 scopus 로고
    • S. Miyamoto, M. Maki, M. J. Schmitt, M. Hatanaka, I. Verma, Proc. Natl. Acad. Sci. U.S.A. 91, 12740 (1994); K. Brown, S. Gerstberger, L. Carlson, G. Franzoso, U. Siebenlist, Science 267, 1485 (1995); E. B.-M. Traenckner et al., EMBO J. 14, 2876 (1995).
    • (1995) Science , vol.267 , pp. 1485
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 28
    • 0028978032 scopus 로고
    • S. Miyamoto, M. Maki, M. J. Schmitt, M. Hatanaka, I. Verma, Proc. Natl. Acad. Sci. U.S.A. 91, 12740 (1994); K. Brown, S. Gerstberger, L. Carlson, G. Franzoso, U. Siebenlist, Science 267, 1485 (1995); E. B.-M. Traenckner et al., EMBO J. 14, 2876 (1995).
    • (1995) EMBO J. , vol.14 , pp. 2876
    • Traenckner, E.B.-M.1
  • 30
    • 10144237991 scopus 로고    scopus 로고
    • note
    • We thank G. Stark for the U3A cells, B. Ren and N. Pandey for comments on the manuscript, and J. E. Darnell for discussing unpublished results. Supported by the Cancer Research Fund of the Damon Runyon-Walter Winchell Foundation (DRG-1329 to T.K.K.) and NIH grant Al20642 (T.M.).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.