Traceless solid-phase synthesis of 2,6,9-trisubstituted purines from resin bound 6-thiopurines

Tetrahedron

Volumn 58, Issue 39, 2002, Pages 7911-7923

  Brun, Virginie ^a   Legraverend, Michel ^a   Grierson, David S ^a  

^a INSTITUT CURIE   (France)

Author keywords

6 chloro 2 iodo 9 THP purine; Palladium catalyzed cross coupling; Solid support

Indexed keywords

(4 CHLOROBENZYL)[2 MORPHOLIN 4 YL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 6 YL]AMINE; 1 [4 [6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL]PHENYL]ETHANONE; 2 [6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL]PHENOL; 2 [6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YLAMINO]ETHANOL; 2 [[6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL]ETHYLAMINO]ETHANOL; 4 [6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL] 2 METHYLBUT 3 YN 2 OL; 4 [6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL]BENZALDEHYDE; 6 [BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL](3 METHOXYBENZYL)AMINE; 6 BENZYLSULFANYL 2 (4 METHOXYPHENYL) 9 (TETRAHYDROPYRAN 2 YL) 9H PURINE; 6 BENZYLSULFANYL 2 IODO 9 (TETRAHYDROPYRAN 2 YL) 9H PURINE; 6 BENZYLSULFANYL 2 MORPHOLIN 4 YL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN; 6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 2 4 TOLYL 9H PURINE; 6 CHLORO 2 IODO 9 (TETRAHYDROPYRAN 2 YL) 9H PURINE; [1 [6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL]PIPERIDIN 2 YL]METHANOL; [1 [6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL]PYRROLIDIN 2 YL]METHANOL; [1 [6 BUTYLAMINO 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL]PIPERIDIN 2 YL]METHANOL; [6 BENZYLSULFANYL 9 (TETRAHYDROPYRAN 2 YL) 9H PURIN 2 YL] 3 METHYLPENT 1 YN 3 OL; AMINE; BENZENE DERIVATIVE; BENZYL DERIVATIVE; ESTER DERIVATIVE; FUNCTIONAL GROUP; MERCAPTOPURINE; N 6 (4 ETHOXYBENZYL) N 2 (3 METHOXYBENZYL) 9 (TETRAHYDROPYRAN 2 YL) 9H PURINE 2,6 DIAMINE; PALLADIUM; PURINE DERIVATIVE; RESIN; SULFONE; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE;

ARTICLE; CATALYSIS; COMBINATORIAL CHEMISTRY; COMBINATORIAL LIBRARY; DRUG SYNTHESIS; OXIDATION; PRIORITY JOURNAL; REACTION ANALYSIS; ROOM TEMPERATURE; SOLID;

LATEOLABRAX JAPONICUS; STAPHYLOCOCCUS PHAGE 3A;

EID: 0037163275     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(02)00905-5     Document Type: Article

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