Combinatorial synthesis of 2,9-substituted purines

Tetrahedron Letters

Volumn 38, Issue 7, 1997, Pages 1161-1164

  Gray, Nathanael S ^a   Kwon, Soojin ^a   Schultz, Peter G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PURINE DERIVATIVE;

ARTICLE; DRUG PURIFICATION; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MASS SPECTROMETRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; THIN LAYER CHROMATOGRAPHY;

EID: 0031575637     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00014-2     Document Type: Article

References (10)

1. 1. Vesely J., Havlicek L., Strnad M., Blow J.J., Donella-Deana A., Pinna L., Letham D.S., Kato J., Detivaud L., Leclerc S., Meijer L. Eur. J. Biochem.. 1994, 224, 771-786.
2. 2. Schulze-Gahmen U., Brandsen J., Jones H.D., Morgan D.O., Meijer L., Vesely J., Kim S.H. PROTEINS. 1995, 22, 378-391.
3. 3. Norman T.C., Gray N.S., Koh J.T. J. Am. Chem. Soc. 1996, 118, 7430-7431.
4. +: 258.1029, Found: 258.1025.
5. 5. a) Albericio F., Kneib-Cordonier N., Biancolana S., Gera L., Masada R. I., Hudson D., Barany G. J. Org. Chem. 1990, 55, 3730-3743.
6. b) Landi Jr. J., Ramig K. Synth. Comm. 1991, 21,167-171.
7. 6. Geysen H.M., Rodda S.J., Mason T.J., Tribbick G., Schoofs. Immunol. Methods. 1987, 102.
8. 7. Toyota A., Katagiri N., Kaneko C. Heterocycle. 1993, 36, 1625-1630.
9. 3N pH = 7.0; solvent B: CH3CN) of 20-100% B over 20 min monitoring at 254 nm. HPLC yields are obtained by integration at 254 nm.
10. +: 328.1886, Found: 328.1882.