Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2',3'- unsaturated L-nucleosides

Journal of Medicinal Chemistry

Volumn 42, Issue 7, 1999, Pages 1320-1328

  Lee, Kyeong ^a   Choi, Yongseok ^a   Gullen, Elizabeth ^c   Schlueter Wirtz, Susan ^b   Schinazi, Raymond F ^b   Cheng, Yung Chi ^c   Chu, Chung K ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YALE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 O ISOPROPYLIDENE GLYCERALDEHYDE; 2' VINYLIC FLUORIDE; 6 CHLORO 2 FLUOROPURINE; 6 CHLOROPURINE; DIDANOSINE; EMTRICITABINE; LAMIVUDINE; N 4 BENZOYL 5 FLUOROCYTOSINE; N 4 BENZOYLCYTOSINE; NUCLEOSIDE DERIVATIVE; PURINE NUCLEOSIDE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CYTOTOXICITY; DRUG SYNTHESIS; HEPATITIS B; HEPATITIS B VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; VERO CELL;

ADENOSINE; ANTI-HIV AGENTS; CELL LINE; CYTOSINE; HEPATITIS B VIRUS; HIV-1; HUMANS; INHIBITORY CONCENTRATION 50; LEUKOCYTES, MONONUCLEAR; PURINE NUCLEOSIDES; PYRIMIDINE NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 0033535597     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980651u     Document Type: Article

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