PTEN: Sometimes taking it off can be better than putting it on

American Journal of Human Genetics

Volumn 61, Issue 6, 1997, Pages 1234-1238

  Myers, M P ^a   Tonks, N K ^a  

^a Watson School of Biological Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOPROTEIN PHOSPHATASE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE;

BANNAYAN ZONANA SYNDROME; CENTRONUCLEAR MYOPATHY; CHROMOSOME 10Q; COWDEN SYNDROME; DIABETES MELLITUS; EDITORIAL; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENETIC DISORDER; GLIOBLASTOMA; HETEROZYGOSITY LOSS; HUMAN; LHERMITTE DUCLOS DISEASE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROSTATE CANCER; TUMOR SUPPRESSOR GENE;

EID: 0031442631     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/301659     Document Type: Editorial

References (31)

1. K Andersson N Carballeira KE Magnusson C Persson O Stendahl H Wolf-Watz M Fallman YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signalling associated with phagocytosis Mol Microbiol 20 1996 1057 1069
2. D Barford AJ Flint NK Tonks Crystal structure of human protein tyrosine phosphatase 1B Science 263 1994 a 1397 1404
3. D Barford Z Jia NK Tonks Protein tyrosine phosphatases take off Nat Struct Biol 2 1995 1043 1053
4. D Barford JC Keller AJ Flint NK Tonks Purification and crystallization of the catalytic domain of human protein tyrosine phosphatase 1B expressed in Escherichia coli J Mol Biol 239 1994 b 726 730
5. N Begum KE Sussman B Draznin Differential effects of diabetes on adipocyte and liver phosphotyrosine and phosphoserine phosphatase activities Diabetes 40 1991 1620 1629
6. M Chrzanowska-Wodnicka K Burridge Tyrosine phosphorylation is involved in reorganization of the actin cytoskeleton in response to serum or LPA stimulation J Cell Sci 107 1994 3643 3654
7. BS Cobb JT Parsons Regulation of the cellular src protein tyrosine kinase: interactions of the carboxyl terminal sequences residing between the kinase domain and tyrosine-527 Oncogene 8 1993 2897 2903
8. C Eng V Murday S Seal S Mohammed SV Hodgson MA Chaudray IS Fentiman Cowden syndrome and Lhermitte-Duclos disease in a family: a single genetic syndrome with pleiotropy? J Med Genet 31 1994 458 461
9. AJ Flint T Tiganis D Barford NK Tonks Development of “substrate-trapping” mutants to identify physiological substrates of protein tyrosine phosphatases Proc Natl Acad Sci USA 94 1997 1680 1685
10. RJ Grolin MM Cohen LM Condon BA Burke Bannayan-Riley-Ruvalcaba syndrome Am J Med Genet 44 1992 307 314
11. LD Howell C Griffiths LW Slade M Potts PJ Kennelly Specificity of IphP, a cyanobacterial dual-specificity protein phosphatase with MAP kinase phosphatase activity Biochemistry 35 1996 7566 7572
12. JK Klarlund Transformation of cells by an inhibitor of phosphatases acting on phosphotyrosine in proteins Cell 41 1985 707 717
13. J Laporte IJ Hu C Kretz JL Mandel P Kioschis JF Coy SM Klauck A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast Nat Genet 13 1996 175 182
14. D-M Li H Sun TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β Cancer Res 57 1997 2124 2129
15. J Li C Yen D Liaw K Podsypanina S Bose S Wang J Puc PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast and prostate cancer Science 275 1997 1943 1946
16. D Liaw DJ Marsh J Li PLM Dahia SI Wang Z Zheng S Bose Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome Nat Genet 16 1997 64 67
17. DJ Marsh PLM Dahia Z Zheng D Liaw P Parsons RJ Gorlin C Eng Germline mutations in PTEN are present in Bannayan-Zonana syndrome Nat Genet 16 1997 333 334
18. MP Myers JP Stolarov C Eng J Li SI Wang MH Wigler R Parsons PTEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase Proc Natl Acad Sci USA 94 1997 9052 9057
19. BG Neel NK Tonks Protein tyrosine phosphatases in signal transduction Curr Opin Cell Biol 9 1997 193 204
20. MR Nelen MCG van Staveren EAJ Peeters M Ben Hassel RJ Gorlin H Hamm CF Lindboe Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease Hum Mol Genet 6 1997 1383 1387
21. MA Pershouse E Stubblefield A Hadi AM Killary WK Yung PA Steck Analysis of the functional role of chromosome 10 loss in human glioblastomas Cancer Res 53 1993 5043 5050
22. R Poon T Hunter Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP, in the absence of cyclin Science 270 1995 90 93
23. E Rhei L Kang F Bogomolniy MG Federici PI Borgen J Boyd Mutational analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas Cancer Res 57 1997 3657 3659
24. PA Steck AH Ligon P Cheong WK Yung MA Pershouse Two tumor suppressive loci on chromosome 10 involved in human glioblastomas Genes Chromosom Cancer 12 1995 255 261
25. PA Steck MA Perhouse SA Jasser WKA Yung H Lin AH Ligon AL Lauren Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers Nat Genet 15 1997 356 362
26. T Takagi CR Moore F Diehn S Buratowski An RNA 5′-triphosphatase related to the protein tyrosine phosphatases Cell 89 1997 867 873
27. H Tashiro MS Blazes R Wu KR Cho S Bose SI Wang J Li Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies Cancer Res 57 1997 3935 3940
28. V van Heyningen One gene—four syndromes Nature 367 1994 319 320
29. A von Deimling DN Louis K von Ammon I Petersen T Hoell RY Chung RL Martuza Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme J Neurosurg 77 1992 295 301
30. J Yuvaniyama JM Denu JE Dixon MA Saper Crystal structure of the dual specificity protein phosphatase VHR Science 272 1996 1328 1331
31. S-H Zhang WR Eckberg Q Yang AA Samatar NK Tonks Biochemical characterization of a human band 4.1–related protein tyrosine phosphatase, PTPH1 J Biol Chem 270 1995 20067 20072