Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells

Cancer Research

Volumn 62, Issue 2, 2002, Pages 466-471

  Yamaguchi, Hirohito ^a,b   Lee, Michael W ^a   Wang, Hong Gang ^a,b   Paranawithana, Shanthi R ^a,b   Bhalla, Kapil N ^a,b   Huang, Ziwei ^c  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOCHROME B; EPOTHILONE B; EPOTHILONE DERIVATIVE; IXABEPILONE; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL CYCLE; DRUG CYTOTOXICITY; DRUG MECHANISM; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; EPOTHILONES; EPOXY COMPOUNDS; G2 PHASE; HUMANS; MITOCHONDRIA; MITOSIS; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0037081329     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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