O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions

Molecular and Cellular Biology

Volumn 17, Issue 11, 1997, Pages 6472-6480

  Roos, Mark D ^a   Su, Kaihong ^a   Baker, John R ^b   Kudlow, Jeffrey E ^c,d  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N ACETYLGLUCOSAMINE; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; HYDROPHOBICITY; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN PROTEIN INTERACTION; STOICHIOMETRY; TRANSCRIPTION REGULATION;

EID: 0030772457     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.11.6472     Document Type: Article

References (33)

1. Chou, T. Y., G. W. Hart, and C. V. Dang. 1995. c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas. J. Biol. Chem. 270:18961-18965.
2. Ciechanover, A. 1994. The ubiquitin-proteasome proteolytic pathway. Cell 79:13-21.
3. Courey, A. J., D. A. Holtzman, S. P. Jackson, and R. Tjian. 1989. Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell 59:827-836.
4. Courey, A. J., and R. Tjian. 1988. Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell 55:887-898.
5. Cress, W. D., and S. J. Triezenburg. 1991. Critical structural elements of the VP16 transcriptional activation domain. Science 251:670-682.
6. Dong, D. L.-Y., and G. W. Hart. 1994. Purification and characterization of an O-GlcNAc selective N-acetyl-β-D-glucosaminidase from rat spleen cytosol. J. Biol. Chem. 269:19321-19330.
7. Ferreri, K., G. Gill, and M. Montminy. 1994. The cAMP-regulated transcription factor CREB interacts with a component of the TFIID complex. Proc. Natl. Acad. Sci. USA 9:1210-1213.
8. Gill, G., E. Pascal, Z. H. Tseng, and R. Tjian. 1994. A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc. Natl. Acad. Sci. USA 91:192-196.
9. Gill, G., and M. Ptashne. 1988. Negative effect of the transcriptional activator Gal4. Nature (London) 334:721-724.
10. Goodrich, J. A., T. Hoey, C. J. Thut, A. Admon, and R. Tjian. 1993. TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB. Cell 75:519-530.
11. Haltiwanger, R. S., M. A. Blomberg, and G. W. Hart. 1992. Glycosylation of nuclear and cytoplasmic proteins. J. Biol. Chem. 267:9005-9013.
12. Han, I., and J. E. Kudlow. 1997. Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility. Mol. Cell. Biol. 17:2550-2558.
13. Hart, G. W. 1997. Dynamic O-GlcNAcylation of nuclear and cytoskeletal proteins. Annu. Rev. Biochem. 66:315-335.
14. Hart, G. W., R. S. Haltiwanger, G. D. Holt, and W. G. Kelly. 1989. Glycosylation in the nucleus and cytoplasm. Annu. Rev. Biochem. 58:841-871.
15. Hoey, T., R. O. J. Weinzierl, G. Gill, J. L. Chen, B. D. Dynlacht, and R. Tjian. 1993. Molecular cloning and functional analysis of Drosophila TAF110 reveals properties expected of coactivators. Cell 72:247-260.
16. Holt, G. D., and G. W. Hart. 1986. The subcellular distribution of terminal N-acetylglucosamine moieties. J. Biol. Chem. 261:8049-8057.
17. Holt, G. D., C. M. Snow, A. Senior, R. S. Haltiwanger, L. Gerace, and G. W. Hart. 1987. Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine. J. Cell Biol. 104:1157-1164.
18. Jackson, S. P., J. J. MacDonald, S. Lees-Miller, and R. Tjian. 1990. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell 63:155-165.
19. Jackson, S. P., and R. Tjian. 1988. O-Glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell 55:125-133.
20. Kadonaga, J. T., A. J. Courey, J. Ladika, and R. Tjian. 1988. Distinct regions of Sp1 modulate DNA binding and transcriptional activation. Science 242: 1566-1570.
21. Kearse, K. P., and G. W. Hart. 1991. Lymphocyte activation induces rapid changes in nuclear and cytoplasmic glycoproteins. Proc. Natl. Acad. Sci. USA 88:1701-1705.
22. Kelly, W. G., M. E. Dahmus, and G. W. Hart. 1993. RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc. J. Biol. Chem. 268:10416-10424.
23. Moss, B. 1991. Vaccinia virus: a tool for research and vaccine development. Science 252:1662-1667.
24. Pascal, E., and R. Tjian. 1991. Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev. 5:1646-1656.
25. Pugh, B. F., and R. Tjian. 1991. Transcription from a TATA-less promoter requires a multi-subunit TFIID complex. Genes Dev. 5:1935-1945.
26. Reason, A. J., H. R. Morris, M. Panico, R. Marais, R. H. Treisman, R. S. Haltiwanger, G. W. Hart, W. G. Kelly, and A. Dell. 1992. Localization of O-GlcNAc modification on the serum response transcription factor. J. Biol. Chem. 267:16911-16921.
27. Sauer, F., S. K. Hansen, and R. Tjian. 1995. DNA template and activator-coactivator requirements for transcriptional synergism by Drosophila Bicoid. Science 270:1825-1828.
28. Sauer, F., D. A. Wassarman, G. M. Rubin, and R. Tjian. 1996. TAFs mediate activation of transcription in the Drosophila embryo. Cell 87:1271-1284.
29. Schindler, M., M. Hogan, R. Miller, and D. DeGaetano. 1987. A nuclear specific glycoprotein representative of a unique pattern of glycosylation. J. Biol. Chem. 262:1254-1260.
30. Shin, T. H., and J. E. Kudlow. 1994. Identification and characterization of the human transforming growth factor a initiator. Mol. Endocrinol. 8:704-712.
31. Starr, C. M., and J. A. Hanover. 1990. Glycosylation of nuclear pore protein p62. Reticulocyte lysate catalyzes O-linked N-acetylglucosamine addition in vitro. J. Biol. Chem. 265:6868-6873.
32. Tanese, N., B. F. Pugh, and R. Tjian. 1991. Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex. Genes Dev. 5:2212-2224.
33. Torres, C., and G. W. Hart. 1984. Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surface of intact lymphocytes. J. Biol. Chem. 259:3308-3317.