TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast

Molecular Cell

Volumn 7, Issue 1, 2001, Pages 117-126

  Wu, Jiansheng ^a   Suka, Noriyuki ^a   Carlson, Marian ^b   Grunstein, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; HISTONE DEACETYLASE;

ACETYLATION; ARTICLE; BINDING SITE; CONTROLLED STUDY; DEACYLATION; DNA STRAND BREAKAGE; ENZYME ACTIVITY; EPISTASIS; GENE REPRESSION; GENE TARGETING; GENETIC CODE; NONHUMAN; OXYGEN CONSUMPTION; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; STRESS; YEAST;

EID: 0035105035     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00160-5     Document Type: Article

References (34)

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4. HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex
5. The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure
6. The organized chromatin domain of the repressed yeast a cell-specific gene STE6 contains two molecules of the corepressor Tup1p per nucleosome
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15. Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo
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19. Functional relationships of Srb10-Srb11 kinase, carboxy-terminal domain kinase CTDK-I, and transcriptional corepressor Ssn6-Tup1
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