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Volumn 67, Issue 16, 2002, Pages 5497-5507

Spiro[2.2]pentane as a dissymmetric scaffold for conformationally constrained analogues of glutamic acid: Focus on racemic 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids

(9) Pellicciari, Roberto a Marinozzi, Maura a Camaioni, Emidio a Nùnez, Maria del Carmen a,d Costantino, Gabriele a Gasparini, Fabrizio b Giorgi, Gianluca c Macchiarulo, Antonio a Subramanian, Natarajan b

a UNIVERSITY OF PERUGIA (Italy)

b NOVARTIS PHARMA AG (Switzerland)

c UNIVERSITY OF SIENA (Italy)

d Facultad de Farmacia (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

LIGANDS;

CONFORMATIONS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

ORGANIC ACIDS;

1 AMINOSPIRO[2.2]PENTYL 1,4 DICARBOXYLIC ACID; AMPA RECEPTOR; GLUTAMIC ACID DERIVATIVE; IONOTROPIC RECEPTOR; KAINIC ACID RECEPTOR; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SPIRO COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DIASTEREOISOMER; DRUG CONFORMATION; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; RACEMIC MIXTURE; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY;

DICARBOXYLIC ACIDS; GLUTAMIC ACID; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PENTANES; SPIRO COMPOUNDS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037047532 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo020138v Document Type: Article

Times cited : (38)

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