Aminobicyclo[2.2.1.]heptane dicarboxylic acids (ABHD), rigid analogs of ACPD and glutamic acid: Synthesis and pharmacological activity on metabotropic receptors mGluR1 and mGluR2

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 2, 1998, Pages 195-208

  Tellier, Frédérique ^a   Acher, Francine ^a   Brabet, Isabelle ^b   Pin, Jean Philippe ^b   Azerad, Robert ^a  

^a CNRS   (France)

^b INSERM   (France)

Author keywords

Aminocyclopentane 1,3 dicarboxylic acid (ACPD); Conformation; Glutamic acid; Metabotropic receptors; Norbornane analog

Indexed keywords

2 AMINOBICYCLO[2.2.1]HEPTANE 2 CARBOXYLIC ACID; CYCLOLEUCINE; GLUTAMIC ACID DERIVATIVE; HYDANTOIN; METABOTROPIC RECEPTOR; NORBORNANE DERIVATIVE; RECEPTOR SUBTYPE;

ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG SYNTHESIS; EMBRYO; GENE EXPRESSION; HUMAN; HUMAN CELL; KIDNEY CELL; MOLECULAR MIMICRY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOLEUCINE; DICARBOXYLIC ACIDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUTAMIC ACID; ISOMERISM; MODELS, CHEMICAL; MOLECULAR CONFORMATION; NORBORNANES; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 0031864695     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)10031-1     Document Type: Article

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