-
1
-
-
0028328817
-
An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct
-
Abe, M., J. G. Harpel, C. N. Metz, I. Nunes, D. J. Loskutoff, and D. B. Rifkin. 1994. An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal. Biochem. 216:276-284.
-
(1994)
Anal. Biochem.
, vol.216
, pp. 276-284
-
-
Abe, M.1
Harpel, J.G.2
Metz, C.N.3
Nunes, I.4
Loskutoff, D.J.5
Rifkin, D.B.6
-
2
-
-
0035908493
-
Blocking oncogenic Ras signaling for cancer therapy
-
Adjei, A. A. 2001. Blocking oncogenic Ras signaling for cancer therapy. J. Natl. Cancer Inst. 93:1062-1074.
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 1062-1074
-
-
Adjei, A.A.1
-
3
-
-
0029827771
-
A role for a p21-E2F interaction during senescence arrest of normal human fibroblasts
-
Afshari, C. A., M. A. Nichols, Y. Xiong, and M. Mudryj. 1996. A role for a p21-E2F interaction during senescence arrest of normal human fibroblasts. Cell Growth Differ. 7:979-988.
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 979-988
-
-
Afshari, C.A.1
Nichols, M.A.2
Xiong, Y.3
Mudryj, M.4
-
4
-
-
0035956972
-
FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle
-
Aghdasi, B., K. Ye, A. Resnick, A. Huang, H. C. Ha, X. Guo, T. M. Dawson, V. L. Dawson, and S. H. Snyder. 2001. FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle. Proc. Natl. Acad. Sci. USA 98:2425-2430.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2425-2430
-
-
Aghdasi, B.1
Ye, K.2
Resnick, A.3
Huang, A.4
Ha, H.C.5
Guo, X.6
Dawson, T.M.7
Dawson, V.L.8
Snyder, S.H.9
-
5
-
-
0028910316
-
Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1
-
Alexandrow, M. G., M. Kawabata, M. Aakre, and H. L. Moses. 1995. Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1. Proc. Natl. Acad. Sci. USA 92:3239-3243.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3239-3243
-
-
Alexandrow, M.G.1
Kawabata, M.2
Aakre, M.3
Moses, H.L.4
-
6
-
-
0034653998
-
c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover
-
Bahram, F., N. von der Lehr, C. Cetinkaya, and L. G. Larsson. 2000. c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover. Blood 95:2104-2110.
-
(2000)
Blood
, vol.95
, pp. 2104-2110
-
-
Bahram, F.1
Von der Lehr, N.2
Cetinkaya, C.3
Larsson, L.G.4
-
7
-
-
0030615329
-
TGF beta in prostate cancer: A growth inhibitor that can enhance tumorigenicity
-
Barrack, E. R. 1997. TGF beta in prostate cancer: A growth inhibitor that can enhance tumorigenicity. Prostate 31:61-70.
-
(1997)
Prostate
, vol.31
, pp. 61-70
-
-
Barrack, E.R.1
-
8
-
-
0027275755
-
Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas
-
Bhatia, K., K. Huppi, G. Spangler, D. Siwarski, R. Iyer, and I. Magrath. 1993. Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas. Nat. Genet. 5:56-61.
-
(1993)
Nat. Genet.
, vol.5
, pp. 56-61
-
-
Bhatia, K.1
Huppi, K.2
Spangler, G.3
Siwarski, D.4
Iyer, R.5
Magrath, I.6
-
9
-
-
0035861541
-
Integrin beta 1 signaling is necessary for transforming growth factorbeta activation of p38MAPK and epithelial plasticity
-
Bhowmick, N. A., R. Zent, M. Ghiassi, M. McDonnell, and H. L. Moses. 2001. Integrin beta 1 signaling is necessary for transforming growth factorbeta activation of p38MAPK and epithelial plasticity. J. Biol. Chem. 276:46707-46713.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46707-46713
-
-
Bhowmick, N.A.1
Zent, R.2
Ghiassi, M.3
McDonnell, M.4
Moses, H.L.5
-
10
-
-
0025068887
-
Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene
-
Bookstein, R., J. Y. Shew, P. L. Chen, P. Scully, and W. H. Lee. 1990. Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene. Science 247:712-715.
-
(1990)
Science
, vol.247
, pp. 712-715
-
-
Bookstein, R.1
Shew, J.Y.2
Chen, P.L.3
Scully, P.4
Lee, W.H.5
-
11
-
-
0031441041
-
Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene
-
Bottinger, E. P., J. L. Jakubczak, D. C. Haines, K. Bagnall, and L. M. Wakefield. 1997. Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene. Cancer Res. 57:5564-5570.
-
(1997)
Cancer Res.
, vol.57
, pp. 5564-5570
-
-
Bottinger, E.P.1
Jakubczak, J.L.2
Haines, D.C.3
Bagnall, K.4
Wakefield, L.M.5
-
12
-
-
0028360374
-
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
-
Brown, E. J., M. W. Albers, T. B. Shin, K. Ichikawa, C. T. Keith, W. S. Lane, and S. L. Schreiber. 1994. A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature 369:756-758.
-
(1994)
Nature
, vol.369
, pp. 756-758
-
-
Brown, E.J.1
Albers, M.W.2
Shin, T.B.3
Ichikawa, K.4
Keith, C.T.5
Lane, W.S.6
Schreiber, S.L.7
-
13
-
-
0030881836
-
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
-
Brunn, G. J., C. C. Hudson, A. Sekulic, J. M. Williams, H. Hosoi, P. J. Houghton, J. C. Lawrence, Jr., and R. T. Abraham. 1997. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science 277:99-101.
-
(1997)
Science
, vol.277
, pp. 99-101
-
-
Brunn, G.J.1
Hudson, C.C.2
Sekulic, A.3
Williams, J.M.4
Hosoi, H.5
Houghton, P.J.6
Lawrence J.C., Jr.7
Abraham, R.T.8
-
14
-
-
0035970035
-
Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program
-
Chen, C. R., Y. Kang, and J. Massague. 2001. Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program. Proc. Natl. Acad. Sci. USA 98:992-999.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 992-999
-
-
Chen, C.R.1
Kang, Y.2
Massague, J.3
-
15
-
-
0030926004
-
Mechanism of TGFbeta receptor inhibition by FKBP12
-
Chen, Y. G., F. Liu, and J. Massague. 1997. Mechanism of TGFbeta receptor inhibition by FKBP12. EMBO J. 16:3866-3876.
-
(1997)
EMBO J.
, vol.16
, pp. 3866-3876
-
-
Chen, Y.G.1
Liu, F.2
Massague, J.3
-
16
-
-
0032563872
-
Insensitivity to growth inhibition by TGF-beta1 correlates with a lack of inhibition of the CDK2 activity in prostate carcinoma cells
-
Cipriano, S. C., and Y. Q. Chen. 1998. Insensitivity to growth inhibition by TGF-beta1 correlates with a lack of inhibition of the CDK2 activity in prostate carcinoma cells. Oncogene 17:1549-1556.
-
(1998)
Oncogene
, vol.17
, pp. 1549-1556
-
-
Cipriano, S.C.1
Chen, Y.Q.2
-
17
-
-
0034662959
-
A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta-induced cell-cycle arrest
-
Claassen, G. F., and S. R. Hann. 2000. A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta-induced cell-cycle arrest. Proc. Natl. Acad. Sci. USA 97:9498-9503.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9498-9503
-
-
Claassen, G.F.1
Hann, S.R.2
-
18
-
-
0033602278
-
A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells
-
Coats, S., P. Whyte, M. L. Fero, S. Lacy, G. Chung, E. Randel, E. Firpo, and J. M. Roberts. 1999. A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells. Curr. Biol. 9:163-173.
-
(1999)
Curr. Biol.
, vol.9
, pp. 163-173
-
-
Coats, S.1
Whyte, P.2
Fero, M.L.3
Lacy, S.4
Chung, G.5
Randel, E.6
Firpo, E.7
Roberts, J.M.8
-
19
-
-
0034698170
-
Inhibition of the phosphoinositide 3-kinase pathway induces a senescence-like arrest mediated by p27Kip1
-
Collado, M., R. H. Medema, I. Garcia-Cao, M. L. Dubuisson, M. Barradas, J. Glassford, C. Rivas, B. M. Burgering, M. Serrano, and E. W. Lam. 2000. Inhibition of the phosphoinositide 3-kinase pathway induces a senescence-like arrest mediated by p27Kip1. J. Biol. Chem. 275:21960-21968.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 21960-21968
-
-
Collado, M.1
Medema, R.H.2
Garcia-Cao, I.3
Dubuisson, M.L.4
Barradas, M.5
Glassford, J.6
Rivas, C.7
Burgering, B.M.8
Serrano, M.9
Lam, E.W.10
-
20
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler, S., S. Itoh, D. Vivien, P. ten Dijke, S. Huet, and J. M. Gauthier. 1998. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17:3091-3100.
-
(1998)
EMBO J.
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
21
-
-
0034901515
-
Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition
-
Dudkin, L., M. B. Dilling, P. J. Cheshire, F. C. Harwood, M. Hollingshead, S. G. Arbuck, R. Travis, E. A. Sausville, and P. J. Houghton. 2001. Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition. Clin. Cancer Res. 7:1758-1764.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1758-1764
-
-
Dudkin, L.1
Dilling, M.B.2
Cheshire, P.J.3
Harwood, F.C.4
Hollingshead, M.5
Arbuck, S.G.6
Travis, R.7
Sausville, E.A.8
Houghton, P.J.9
-
22
-
-
0028988787
-
Transforming growth factor-beta receptors on human endometrial cells: Identification of the type I, II, and III receptors and glycosyl-phosphatidylinositol anchored TGF-beta binding proteins
-
Dumont, N., M. D. O'Connor-McCourt, and A. Philip. 1995. Transforming growth factor-beta receptors on human endometrial cells: Identification of the type I, II, and III receptors and glycosyl-phosphatidylinositol anchored TGF-beta binding proteins. Mol. Cell. Endocrinol. 111:57-66.
-
(1995)
Mol. Cell. Endocrinol.
, vol.111
, pp. 57-66
-
-
Dumont, N.1
O'Connor-McCourt, M.D.2
Philip, A.3
-
23
-
-
0034682805
-
Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia
-
Feng, L. X., N. Ravindranath, and M. Dym. 2000. Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia. J. Biol. Chem. 275:25572-25576.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25572-25576
-
-
Feng, L.X.1
Ravindranath, N.2
Dym, M.3
-
24
-
-
0036159130
-
Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)
-
Feng, X. H., Y. Y. Liang, M. Liang, W. Zhai, and X. Lin. 2002. Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B). Mol. Cell 9:133-143.
-
(2002)
Mol. Cell
, vol.9
, pp. 133-143
-
-
Feng, X.H.1
Liang, Y.Y.2
Liang, M.3
Zhai, W.4
Lin, X.5
-
25
-
-
0035866358
-
Antitumor activity of the rapamycin analog CCI-779 in human primitive neuroectodermal tumor/medulloblastoma models as single agent and in combination chemotherapy
-
Geoerger, B., K. Kerr, C. B. Tang, K. M. Fung, B. Powell, L. N. Sutton, P. C. Phillips, and A. J. Janss. 2001. Antitumor activity of the rapamycin analog CCI-779 in human primitive neuroectodermal tumor/medulloblastoma models as single agent and in combination chemotherapy. Cancer Res. 61:1527-1532.
-
(2001)
Cancer Res.
, vol.61
, pp. 1527-1532
-
-
Geoerger, B.1
Kerr, K.2
Tang, C.B.3
Fung, K.M.4
Powell, B.5
Sutton, L.N.6
Phillips, P.C.7
Janss, A.J.8
-
26
-
-
0022553449
-
Growth factors and cancer
-
Goustin, A. S., E. B. Leof, G. D. Shipley, and H. L. Moses. 1986. Growth factors and cancer. Cancer Res. 46:1015-1029.
-
(1986)
Cancer Res.
, vol.46
, pp. 1015-1029
-
-
Goustin, A.S.1
Leof, E.B.2
Shipley, G.D.3
Moses, H.L.4
-
27
-
-
0033178702
-
Regulation of cell growth and cyclin D1 expression by the constitutively active FRAP-p70s6K pathway in human pancreatic cancer cells
-
Grewe, M., F. Gansauge, R. M. Schmid, G. Adler, and T. Seufferlein. 1999. Regulation of cell growth and cyclin D1 expression by the constitutively active FRAP-p70s6K pathway in human pancreatic cancer cells. Cancer Res. 59:3581-3587.
-
(1999)
Cancer Res.
, vol.59
, pp. 3581-3587
-
-
Grewe, M.1
Gansauge, F.2
Schmid, R.M.3
Adler, G.4
Seufferlein, T.5
-
28
-
-
0030061451
-
Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity
-
Guadagno, T. M., and J. W. Newport. 1996. Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity. Cell 84:73-82.
-
(1996)
Cell
, vol.84
, pp. 73-82
-
-
Guadagno, T.M.1
Newport, J.W.2
-
29
-
-
0032485937
-
Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability
-
Hashermolhosseini, S., Y. Nagamine, S. J. Morley, S. Desrivieres, L. Mercep, and S. Ferrari. 1998. Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability. J. Biol. Chem. 273:14424-14429.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14424-14429
-
-
Hashermolhosseini, S.1
Nagamine, Y.2
Morley, S.J.3
Desrivieres, S.4
Mercep, L.5
Ferrari, S.6
-
30
-
-
0025776523
-
Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast
-
Heitman, J., N. R. Movva, and M. N. Hall. 1991. Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 253:905-909.
-
(1991)
Science
, vol.253
, pp. 905-909
-
-
Heitman, J.1
Movva, N.R.2
Hall, M.N.3
-
31
-
-
0035923594
-
FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse
-
Hentges, K. E., B. Sirry, A. C. Gingeras, D. Sarbassov, N. Sonenberg, D. Sabatini, and A. S. Peterson. 2001. FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse. Proc. Natl. Acad. Sci. USA 98:13796-13801.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13796-13801
-
-
Hentges, K.E.1
Sirry, B.2
Gingeras, A.C.3
Sarbassov, D.4
Sonenberg, N.5
Sabatini, D.6
Peterson, A.S.7
-
32
-
-
0024670325
-
E1A-dependent transactivation of the human MYC promoter is mediated by the E2F factor
-
Hiebert, S. W., M. Lipp, and J. R. Nevins. 1989. E1A-dependent transactivation of the human MYC promoter is mediated by the E2F factor. Proc. Natl. Acad. Sci. USA 86:3594-3598.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 3594-3598
-
-
Hiebert, S.W.1
Lipp, M.2
Nevins, J.R.3
-
33
-
-
0029001787
-
A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain
-
Hoang, A. T., B. Lutterbach, B. C. Lewis, T. Yano, T.-Y. Chou, J. F. Barrett, M. Raffeld, S. R. Hann, and C. V. Dang. 1995. A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain. Mol. Cell. Biol. 15:4031-4042.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 4031-4042
-
-
Hoang, A.T.1
Lutterbach, B.2
Lewis, B.C.3
Yano, T.4
Chou, T.-Y.5
Barrett, J.F.6
Raffeld, M.7
Hann, S.R.8
Dang, C.V.9
-
34
-
-
0031755688
-
Studies on the mechanism of resistance to rapamycin in human cancer cells
-
Hosoi, H., M. B. Dilling, L. N. Liu, M. K. Danks, T. Shikata, A. Sekulic, R. T. Abraham, J. C. Lawrence, Jr., and P. J. Houghton. 1998. Studies on the mechanism of resistance to rapamycin in human cancer cells. Mol. Pharmacol. 54:815-824.
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 815-824
-
-
Hosoi, H.1
Dilling, M.B.2
Liu, L.N.3
Danks, M.K.4
Shikata, T.5
Sekulic, A.6
Abraham, R.T.7
Lawrence J.C., Jr.8
Houghton, P.J.9
-
35
-
-
0027340547
-
Release from G1 growth arrest by transforming growth factor beta 1 requires cellular ras activity
-
Howe, P. H., S. F. Dobrowolski, K. B. Reddy, and D. W. Stacey. 1993. Release from G1 growth arrest by transforming growth factor beta 1 requires cellular ras activity. J. Biol. Chem. 268:21448-21452.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21448-21452
-
-
Howe, P.H.1
Dobrowolski, S.F.2
Reddy, K.B.3
Stacey, D.W.4
-
36
-
-
0034677549
-
NF-kappa B is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis
-
Jo, H., R. Zhang, H. Zhang, T. A. McKinsey, J. Shao, R. D. Beauchamp, D. W. Ballard, and P. Liang. 2000. NF-kappa B is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis. Oncogene 19:841-849.
-
(2000)
Oncogene
, vol.19
, pp. 841-849
-
-
Jo, H.1
Zhang, R.2
Zhang, H.3
McKinsey, T.A.4
Shao, J.5
Beauchamp, R.D.6
Ballard, D.W.7
Liang, P.8
-
37
-
-
0025881661
-
Tumorigenic transformation of NIH 3T3 cells by the autocrine synthesis of transforming growth factor alpha
-
Ju, W. D., T. J. Velu, W. C. Vass, A. G. Papageorge, and D. R. Lowy. 1991. Tumorigenic transformation of NIH 3T3 cells by the autocrine synthesis of transforming growth factor alpha. New Biol. 3:380-388.
-
(1991)
New Biol.
, vol.3
, pp. 380-388
-
-
Ju, W.D.1
Velu, T.J.2
Vass, W.C.3
Papageorge, A.G.4
Lowy, D.R.5
-
38
-
-
0025787009
-
The effect of H-ras oncogene transfection on response of mink lung epithelial cells to growth factors and cytotoxic drugs
-
Kerr, D. I., J. A. Plumb, R. I. Freshney, M. Z. Khan, and D. A. Spandidos. 1991. The effect of H-ras oncogene transfection on response of mink lung epithelial cells to growth factors and cytotoxic drugs. Anticancer Res. 11:1349-1352.
-
(1991)
Anticancer Res.
, vol.11
, pp. 1349-1352
-
-
Kerr, D.I.1
Plumb, J.A.2
Freshney, R.I.3
Khan, M.Z.4
Spandidos, D.A.5
-
39
-
-
0023110029
-
Transforming growth factors and control of neoplastic cell growth
-
Keski-Oja, J., E. B. Leof, R. M. Lyons, R. J. Coffey, Jr., and H. L. Moses. 1987. Transforming growth factors and control of neoplastic cell growth. J. Cell. Biochem. 33:95-107.
-
(1987)
J. Cell. Biochem.
, vol.33
, pp. 95-107
-
-
Keski-Oja, J.1
Leof, E.B.2
Lyons, R.M.3
Coffey R.J., Jr.4
Moses, H.L.5
-
40
-
-
0029071190
-
Efficient screening of retroviral cDNA expression libraries
-
Kitamura, T., M. Onishi, S. Kinoshita, A. Shibuya, A. Miyajima, and G. P. Nolan. 1995. Efficient screening of retroviral cDNA expression libraries. Proc. Natl. Acad. Sci. USA 92:9146-9150.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9146-9150
-
-
Kitamura, T.1
Onishi, M.2
Kinoshita, S.3
Shibuya, A.4
Miyajima, A.5
Nolan, G.P.6
-
41
-
-
0032474586
-
TGF-beta1 effects on proliferation of rat intestinal epithelial cells are due to inhibition of cyclin D1 expression
-
Ko, T. C., W. Yu, T. Sakai, H. Sheng, J. Shao, R. D. Beauchamp, and E. A. Thompson. 1998. TGF-beta1 effects on proliferation of rat intestinal epithelial cells are due to inhibition of cyclin D1 expression. Oncogene 16:3445-3454.
-
(1998)
Oncogene
, vol.16
, pp. 3445-3454
-
-
Ko, T.C.1
Yu, W.2
Sakai, T.3
Sheng, H.4
Shao, J.5
Beauchamp, R.D.6
Thompson, E.A.7
-
42
-
-
0033582455
-
Inhibition of DNA synthesis by a farnesyltransferase inhibitor involves inhibition of the p70(s6k) pathway
-
Law, B. K., P. Norgaard, L. Gnudi, B. B. Kahn, H. S. Poulson, and H. L. Moses. 1999. Inhibition of DNA synthesis by a farnesyltransferase inhibitor involves inhibition of the p70(s6k) pathway. J. Biol. Chem. 274:4743-4748.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 4743-4748
-
-
Law, B.K.1
Norgaard, P.2
Gnudi, L.3
Kahn, B.B.4
Poulson, H.S.5
Moses, H.L.6
-
43
-
-
0034624043
-
Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-Myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen
-
Law, B. K., M. E. Waltner-Law, A. J. Entingh, A. Chytil, M. E. Aakre, P. Norgaard, and H. L. Moses. 2000. Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-Myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen. J. Biol. Chem. 275:38261-38267.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38261-38267
-
-
Law, B.K.1
Waltner-Law, M.E.2
Entingh, A.J.3
Chytil, A.4
Aakre, M.E.5
Norgaard, P.6
Moses, H.L.7
-
44
-
-
0035419867
-
ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways
-
Lenferink, A. E., D. Busse, W. M. Flanagan, F. M. Yakes, and C. L. Arteaga. 2001. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways. Cancer Res. 61:6583-6591.
-
(2001)
Cancer Res.
, vol.61
, pp. 6583-6591
-
-
Lenferink, A.E.1
Busse, D.2
Flanagan, W.M.3
Yakes, F.M.4
Arteaga, C.L.5
-
45
-
-
0030995824
-
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
-
Erratum, 387:932
-
Leone, G., J. DeGregori, R. Sears, L. Jakoi, and J. R. Nevins. 1997. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature 387:422-426. (Erratum, 387:932.)
-
(1997)
Nature
, vol.387
, pp. 422-426
-
-
Leone, G.1
DeGregori, J.2
Sears, R.3
Jakoi, L.4
Nevins, J.R.5
-
46
-
-
0030946933
-
E2F4-RB and E2F4-p107 complexes suppress gene expression by transforming growth factor beta through E2F binding sites
-
Li, J. M., P. P. Hu, X. Shen, Y. Yu, and X. F. Wang. 1997. E2F4-RB and E2F4-p107 complexes suppress gene expression by transforming growth factor beta through E2F binding sites. Proc. Natl. Acad. Sci. USA 94:4948-4953.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4948-4953
-
-
Li, J.M.1
Hu, P.P.2
Shen, X.3
Yu, Y.4
Wang, X.F.5
-
48
-
-
0030886204
-
Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
-
Liu, X., Y. Sun, S. N. Constantinescu, E. Karam, R. A. Weinberg, and H. F. Lodish. 1997. Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc. Natl. Acad. Sci. USA 94:10669-10674.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10669-10674
-
-
Liu, X.1
Sun, Y.2
Constantinescu, S.N.3
Karam, E.4
Weinberg, R.A.5
Lodish, H.F.6
-
49
-
-
0034735895
-
Disruption of TGF-beta growth inhibition by oncogenic ras is linked to p27Kip1 mislocalization
-
Liu, X., Y. Sun, M. Ehrlich, T. Lu, Y. Kloog, R. A. Weinberg, H. F. Lodish, and Y. I. Henis. 2000. Disruption of TGF-beta growth inhibition by oncogenic ras is linked to p27Kip1 mislocalization. Oncogene 19:5926-5935.
-
(2000)
Oncogene
, vol.19
, pp. 5926-5935
-
-
Liu, X.1
Sun, Y.2
Ehrlich, M.3
Lu, T.4
Kloog, Y.5
Weinberg, R.A.6
Lodish, H.F.7
Henis, Y.I.8
-
50
-
-
0028825698
-
TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin
-
Lorenz, M. C., and J. Heitman. 1995. TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. J. Biol. Chem. 270:27531-27537.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27531-27537
-
-
Lorenz, M.C.1
Heitman, J.2
-
51
-
-
0033145516
-
Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A
-
Meraldi, P., J. Lukas, A. M. Fry, J. Bartek, and E. A. Nigg. 1999. Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nat. Cell Biol. 1:88-93.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 88-93
-
-
Meraldi, P.1
Lukas, J.2
Fry, A.M.3
Bartek, J.4
Nigg, E.A.5
-
52
-
-
0026529607
-
Three distinct elements within the murine c-myc promoter are required for transcription
-
Moberg, K. H., T. J. Logan, W. A. Tyndall, and D. J. Hall. 1992. Three distinct elements within the murine c-myc promoter are required for transcription. Oncogene 7:411-421.
-
(1992)
Oncogene
, vol.7
, pp. 411-421
-
-
Moberg, K.H.1
Logan, T.J.2
Tyndall, W.A.3
Hall, D.J.4
-
53
-
-
0025352187
-
Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
-
Morgenstern, J. P., and H. Land. 1990. Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 18:3587-3596.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 3587-3596
-
-
Morgenstern, J.P.1
Land, H.2
-
54
-
-
0023514826
-
Transforming growth factor beta regulation of cell proliferation
-
Moses, H. L., R. J. Coffey, Jr., E. B. Leof, R. M. Lyons, and J. Keski-Oja. 1987. Transforming growth factor beta regulation of cell proliferation. J. Cell. Physiol. Suppl. 5(Suppl.):1-7.
-
(1987)
J. Cell. Physiol. Suppl.
, vol.5
, Issue.SUPPL.
, pp. 1-7
-
-
Moses, H.L.1
Coffey R.J., Jr.2
Leof, E.B.3
Lyons, R.M.4
Keski-Oja, J.5
-
55
-
-
0032491579
-
Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway
-
Muise-Helmericks, R. C., H. L. Grimes, A. Bellacosa, S. E. Malstrom, P. N. Tsichlis, and N. Rosen. 1998. Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway. J. Biol. Chem. 273:29864-29872.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29864-29872
-
-
Muise-Helmericks, R.C.1
Grimes, H.L.2
Bellacosa, A.3
Malstrom, S.E.4
Tsichlis, P.N.5
Rosen, N.6
-
56
-
-
0026863599
-
Transforming growth factor beta 1 regulation of c-myc expression, pRB phosphorylation, and cell cycle progression in keratinocytes
-
Munger, K., J. A. Pietenpol, M. R. Pittelkow, J. T. Holt, and H. L. Moses. 1992. Transforming growth factor beta 1 regulation of c-myc expression, pRB phosphorylation, and cell cycle progression in keratinocytes. Cell Growth Differ. 3:291-298.
-
(1992)
Cell Growth Differ.
, vol.3
, pp. 291-298
-
-
Munger, K.1
Pietenpol, J.A.2
Pittelkow, M.R.3
Holt, J.T.4
Moses, H.L.5
-
57
-
-
0033593055
-
Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity
-
Nagahara, H., S. A. Ezhevsky, A. M. Vocero-Akbani, P. Kaldis, M. J. Solomon, and S. F. Dowdy. 1999. Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity. Proc. Natl. Acad. Sci. USA 96:14961-14966.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14961-14966
-
-
Nagahara, H.1
Ezhevsky, S.A.2
Vocero-Akbani, A.M.3
Kaldis, P.4
Solomon, M.J.5
Dowdy, S.F.6
-
58
-
-
0030010591
-
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
Nakayama, K., N. Ishida, M. Shirane, A. Inomata, T. Inoue, N. Shishido, I. Horii, and D. Y. Loh. 1996. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85:707-720.
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inomata, A.4
Inoue, T.5
Shishido, N.6
Horii, I.7
Loh, D.Y.8
-
59
-
-
0033551374
-
MYC oncogenes and human neoplastic disease
-
Nesbit, C. E., J. M. Tersak, and E. V. Prochownik. 1999. MYC oncogenes and human neoplastic disease. Oncogene 18:3004-3016.
-
(1999)
Oncogene
, vol.18
, pp. 3004-3016
-
-
Nesbit, C.E.1
Tersak, J.M.2
Prochownik, E.V.3
-
60
-
-
17944377486
-
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
-
Neshat, M. S., I. K. Mellinghoff, C. Tran, B. Stiles, G. Thomas, R. Petersen, P. Frost, J. J. Gibbons, H. Wu, and C. L. Sawyers. 2001. Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proc. Natl. Acad. Sci. USA 98:10314-10319.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10314-10319
-
-
Neshat, M.S.1
Mellinghoff, I.K.2
Tran, C.3
Stiles, B.4
Thomas, G.5
Petersen, R.6
Frost, P.7
Gibbons, J.J.8
Wu, H.9
Sawyers, C.L.10
-
61
-
-
0028172867
-
Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin
-
Nourse, J., E. Firpo, W. M. Flanagan, S. Coats, K. Polyak, M. H. Lee, J. Massague, G. R. Crabtree, and J. M. Roberts. 1994. Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin. Nature 372:570-573.
-
(1994)
Nature
, vol.372
, pp. 570-573
-
-
Nourse, J.1
Firpo, E.2
Flanagan, W.M.3
Coats, S.4
Polyak, K.5
Lee, M.H.6
Massague, J.7
Crabtree, G.R.8
Roberts, J.M.9
-
62
-
-
0029786480
-
Characterization of the interaction of FKBP12 with the transforming growth factor-beta type I receptor in vivo
-
Okadome, T., E. Oeda, M. Saitoh, H. Ichijo, H. L. Moses, K. Miyazono, and M. Kawabata. 1996. Characterization of the interaction of FKBP12 with the transforming growth factor-beta type I receptor in vivo. J. Biol. Chem. 271:21687-21690.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21687-21690
-
-
Okadome, T.1
Oeda, E.2
Saitoh, M.3
Ichijo, H.4
Moses, H.L.5
Miyazono, K.6
Kawabata, M.7
-
63
-
-
0034214211
-
Mitogenic conversion of transforming growth factor-betal effect by oncogenic Ha-Rasinduced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer
-
Park, B. J., J. I. Park, D. S. Byun, J. H. Park, and S. G. Chi. 2000. Mitogenic conversion of transforming growth factor-betal effect by oncogenic Ha-Rasinduced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer. Cancer Res. 60:3031-3038.
-
(2000)
Cancer Res.
, vol.60
, pp. 3031-3038
-
-
Park, B.J.1
Park, J.I.2
Byun, D.S.3
Park, J.H.4
Chi, S.G.5
-
64
-
-
0035153463
-
Role of transforming growth factor beta in cancer
-
Pasche, B. 2001. Role of transforming growth factor beta in cancer. J. Cell. Physiol. 186:153-168.
-
(2001)
J. Cell. Physiol.
, vol.186
, pp. 153-168
-
-
Pasche, B.1
-
65
-
-
0033570376
-
TbetaR-1(6A) is a candidate tumor susceptibility allele
-
Pasche, B., P. Kolachana, K. Nafa, J. Satagopan, Y. G. Chen, R. S. Lo, D. Brener, D. Yang, L. Kirstein, C. Oddoux, H. Ostrer, P. Vineis, L. Varesco, S. Jhanwar, L. Luzzatto, J. Massague, and K. Offit. 1999. TbetaR-1(6A) is a candidate tumor susceptibility allele. Cancer Res. 59:5678-5682.
-
(1999)
Cancer Res.
, vol.59
, pp. 5678-5682
-
-
Pasche, B.1
Kolachana, P.2
Nafa, K.3
Satagopan, J.4
Chen, Y.G.5
Lo, R.S.6
Brener, D.7
Yang, D.8
Kirstein, L.9
Oddoux, C.10
Ostrer, H.11
Vineis, P.12
Varesco, L.13
Jhanwar, S.14
Luzzatto, L.15
Massague, J.16
Offit, K.17
-
66
-
-
0029010734
-
Mammary tumor suppression by transforming growth factor beta 1 transgene expression
-
Pierce, D. F., Jr., A. E. Gorska, A. Chytil, K. S. Meise, D. L. Page, R. J. Coffey, Jr., and H. L. Moses. 1995. Mammary tumor suppression by transforming growth factor beta 1 transgene expression. Proc. Natl. Acad. Sci. USA 92:4254-4258.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4254-4258
-
-
Pierce D.F., Jr.1
Gorska, A.E.2
Chytil, A.3
Meise, K.S.4
Page, D.L.5
Coffey R.J., Jr.6
Moses, H.L.7
-
67
-
-
0025787969
-
Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product
-
Pietenpol, J. A., K. Munger, P. M. Howley, R. W. Stein, and H. L. Moses. 1991. Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product. Proc. Natl. Acad. Sci. USA 88:10227-10231.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10227-10231
-
-
Pietenpol, J.A.1
Munger, K.2
Howley, P.M.3
Stein, R.W.4
Moses, H.L.5
-
68
-
-
0025348820
-
TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains
-
Pietenpol, J. A., R. W. Stein, E. Moran, P. Yaciuk, R. Schlegel, R. M. Lyons, M. R. Pittelkow, K. Munger, P. M. Howley, and H. L. Moses. 1990. TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell 61:777-785.
-
(1990)
Cell
, vol.61
, pp. 777-785
-
-
Pietenpol, J.A.1
Stein, R.W.2
Moran, E.3
Yaciuk, P.4
Schlegel, R.5
Lyons, R.M.6
Pittelkow, M.R.7
Munger, K.8
Howley, P.M.9
Moses, H.L.10
-
69
-
-
0028115718
-
Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo
-
Pulverer, B. J., C. Fisher, K. Vousden, T. Littlewood, G. Evan, and J. R. Woodgett. 1994. Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo. Oncogene 9:59-70.
-
(1994)
Oncogene
, vol.9
, pp. 59-70
-
-
Pulverer, B.J.1
Fisher, C.2
Vousden, K.3
Littlewood, T.4
Evan, G.5
Woodgett, J.R.6
-
70
-
-
0028175455
-
Nuclear localization of p85s6k: Functional requirement for entry into S phase
-
Reinhard, C., A. Fernandez, N. J. Lamb, and G. Thomas. 1994. Nuclear localization of p85s6k: Functional requirement for entry into S phase. EMBO J. 13:1557-1565.
-
(1994)
EMBO J.
, vol.13
, pp. 1557-1565
-
-
Reinhard, C.1
Fernandez, A.2
Lamb, N.J.3
Thomas, G.4
-
71
-
-
0028239893
-
RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
-
Sabatini, D. M., H. Erdjument-Bromage, M. Lui, P. Tempst, and S. H. Snyder. 1994. RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell 78:35-43.
-
(1994)
Cell
, vol.78
, pp. 35-43
-
-
Sabatini, D.M.1
Erdjument-Bromage, H.2
Lui, M.3
Tempst, P.4
Snyder, S.H.5
-
72
-
-
0033081027
-
Destruction of Myc by ubiquitin-mediated proteolysis: Cancer-associated and transforming mutations stabilize Myc
-
Salghetti, S. E., S. Y. Kim, and W. P. Tansey. 1999. Destruction of Myc by ubiquitin-mediated proteolysis: Cancer-associated and transforming mutations stabilize Myc. EMBO J. 18:717-726.
-
(1999)
EMBO J.
, vol.18
, pp. 717-726
-
-
Salghetti, S.E.1
Kim, S.Y.2
Tansey, W.P.3
-
73
-
-
0028873133
-
Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression
-
Schwarz, J. K., C. H. Bassing, I. Kovesdi, M. B. Datto, M. Blazing, S. George, X. F. Wang, and J. R. Nevins. 1995. Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression. Proc. Natl. Acad. Sci. USA 92:483-487.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 483-487
-
-
Schwarz, J.K.1
Bassing, C.H.2
Kovesdi, I.3
Datto, M.B.4
Blazing, M.5
George, S.6
Wang, X.F.7
Nevins, J.R.8
-
74
-
-
0034744956
-
TGFbeta influences Mye, Miz-1 and Smad to control the CDK inhibitor p15INK4b
-
Seoane, J., C. Pouponnot, P. Staller, M. Schader, M. Eilers, and J. Massague. 2001, TGFbeta influences Mye, Miz-1 and Smad to control the CDK inhibitor p15INK4b. Nat. Cell Biol. 3:400-408.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 400-408
-
-
Seoane, J.1
Pouponnot, C.2
Staller, P.3
Schader, M.4
Eilers, M.5
Massague, J.6
-
75
-
-
0029849620
-
Cancer cell cycles
-
Sherr, C. J. 1996. Cancer cell cycles. Science 274:1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
76
-
-
0034744957
-
Repression of p15INK4b expression by Myc through association with Miz-1
-
Staller, P., K. Peukert, A. Kiermaier, J. Seoane, J. Lukas, H. Karsunky, T. Moroy, J. Bartek, J. Massague, F. Hanel, and M. Eilers. 2001. Repression of p15INK4b expression by Myc through association with Miz-1. Nat. Cell Biol. 3:392-399.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 392-399
-
-
Staller, P.1
Peukert, K.2
Kiermaier, A.3
Seoane, J.4
Lukas, J.5
Karsunky, H.6
Moroy, T.7
Bartek, J.8
Massague, J.9
Hanel, F.10
Eilers, M.11
-
77
-
-
0031874150
-
TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins
-
Stockwell, B. R., and S. L. Schreiber. 1998. TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins. Chem. Biol. 5:385-395.
-
(1998)
Chem. Biol.
, vol.5
, pp. 385-395
-
-
Stockwell, B.R.1
Schreiber, S.L.2
-
78
-
-
2642614530
-
Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency
-
Tang, B., E. P. Bottinger, S. B. Jakowlew, K. M. Bagnall, J. Mariano, M. R. Anver, J. J. Letterio, and L. M. Wakefield. 1998. Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency. Nat. Med. 4:802-807.
-
(1998)
Nat. Med.
, vol.4
, pp. 802-807
-
-
Tang, B.1
Bottinger, E.P.2
Jakowlew, S.B.3
Bagnall, K.M.4
Mariano, J.5
Anver, M.R.6
Letterio, J.J.7
Wakefield, L.M.8
-
79
-
-
9044253703
-
Alterations of the retinoblastoma gene in human prostate adenocarcinoma
-
Tricoli, J. V., P. H. Gumerlock, J. L. Yao, S. G. Chi, S. A. D'Souza, B. R. Nestok, and R. W. deVere White. 1996. Alterations of the retinoblastoma gene in human prostate adenocarcinoma. Genes Chromosomes Cancer 15:108-114.
-
(1996)
Genes Chromosomes Cancer
, vol.15
, pp. 108-114
-
-
Tricoli, J.V.1
Gumerlock, P.H.2
Yao, J.L.3
Chi, S.G.4
D'Souza, S.A.5
Nestok, B.R.6
DeVere White, R.W.7
-
80
-
-
0030576525
-
The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors
-
Wang, T., B. Y. Li, P. D. Danielson, P. C. Shah, S. Rockwell, R. J. Lechleider, J. Martin, T. Manganaro, and P. K. Donahoe. 1996. The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors. Cell 86:435-444.
-
(1996)
Cell
, vol.86
, pp. 435-444
-
-
Wang, T.1
Li, B.Y.2
Danielson, P.D.3
Shah, P.C.4
Rockwell, S.5
Lechleider, R.J.6
Martin, J.7
Manganaro, T.8
Donahoe, P.K.9
-
82
-
-
0032514376
-
Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway
-
West, M. J., M. Stoneley, and A. E. Willis. 1998. Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway. Oncogene 17:769-780.
-
(1998)
Oncogene
, vol.17
, pp. 769-780
-
-
West, M.J.1
Stoneley, M.2
Willis, A.E.3
-
83
-
-
1842413645
-
p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity
-
Woo, M. S.-A., I. Sánchez, and B. D. Dynlacht. 1997. p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity. Mol. Cell. Biol. 17:3566-3579.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3566-3579
-
-
Woo, M.S.-A.1
Sánchez, I.2
Dynlacht, B.D.3
-
85
-
-
0035936113
-
The E2F1-3 transcription factors are essential for cellular proliferation
-
Wu, L., C. Timmers, B. Maiti, H. I. Saavedra, L. Sang, G. T. Chong, F. Nuckolls, P. Giangrande, F. A. Wright, S. J. Field, M. E. Greenberg, S. Orkin, J. R. Nevins, M. L. Robinson, and G. Leone. 2001. The E2F1-3 transcription factors are essential for cellular proliferation. Nature 414:457-462.
-
(2001)
Nature
, vol.414
, pp. 457-462
-
-
Wu, L.1
Timmers, C.2
Maiti, B.3
Saavedra, H.I.4
Sang, L.5
Chong, G.T.6
Nuckolls, F.7
Giangrande, P.8
Wright, F.A.9
Field, S.J.10
Greenberg, M.E.11
Orkin, S.12
Nevins, J.R.13
Robinson, M.L.14
Leone, G.15
-
86
-
-
0037016689
-
c-myc is a downstream target of the Smad pathway
-
Yagi, K., M. Furuhashi, H. Aoki, D. Goto, H. Kuwano, K. Sugamura, K. Miyazono, and M. Kato. 2002. c-myc is a downstream target of the Smad pathway. J. Biol. Chem. 277:854-861.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 854-861
-
-
Yagi, K.1
Furuhashi, M.2
Aoki, H.3
Goto, D.4
Kuwano, H.5
Sugamura, K.6
Miyazono, K.7
Kato, M.8
-
87
-
-
0027220503
-
Clustered mutations in the second exon of the MYC gene in sporadic Burkitt's lymphoma
-
Yano, T., C. A. Sander, H. M. Clark, M. V. Dolezal, E. S. Jaffe, and M. Raffeld. 1993. Clustered mutations in the second exon of the MYC gene in sporadic Burkitt's lymphoma. Oncogene 8:2741-2748.
-
(1993)
Oncogene
, vol.8
, pp. 2741-2748
-
-
Yano, T.1
Sander, C.A.2
Clark, H.M.3
Dolezal, M.V.4
Jaffe, E.S.5
Raffeld, M.6
-
88
-
-
0034790016
-
mTOR, a novel target in breast cancer: The effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer
-
Yu, K., L. Toral-Barza, C. Discafani, W. G. Zhang, J. Skotnicki, P. Frost, and J. J. Gibbons. 2001. mTOR, a novel target in breast cancer: The effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer. Endocr. Relat. Cancer 8:249-258.
-
(2001)
Endocr. Relat. Cancer
, vol.8
, pp. 249-258
-
-
Yu, K.1
Toral-Barza, L.2
Discafani, C.3
Zhang, W.G.4
Skotnicki, J.5
Frost, P.6
Gibbons, J.J.7
-
89
-
-
0026055060
-
Early gene responses to transforming growth factor-β in cells lacking growthsuppressive RB function
-
Zentella, A., F. M. B. Weis, D. A. Ralph, M. Laiho, and J. Massagué. 1991. Early gene responses to transforming growth factor-β in cells lacking growthsuppressive RB function. Mol. Cell. Biol. 11:4952-4958.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 4952-4958
-
-
Zentella, A.1
Weis, F.M.B.2
Ralph, D.A.3
Laiho, M.4
Massagué, J.5
-
90
-
-
0028983384
-
p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F
-
Zhu, L., E. Harlow, and B. D. Dynlacht. 1995. p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F. Genes Dev. 9:1740-1752.
-
(1995)
Genes Dev.
, vol.9
, pp. 1740-1752
-
-
Zhu, L.1
Harlow, E.2
Dynlacht, B.D.3
-
91
-
-
0035853883
-
Association between the T29→C polymorphism in the transforming growth factor beta1 gene and breast cancer among elderly white women: The study of osteoporotic fractures
-
Ziv, E., J. Cauley, P. A. Morin, R. Saiz, and W. S. Browner. 2001. Association between the T29→C polymorphism in the transforming growth factor beta1 gene and breast cancer among elderly white women: The study of osteoporotic fractures. JAMA 285:2859-2863.
-
(2001)
JAMA
, vol.285
, pp. 2859-2863
-
-
Ziv, E.1
Cauley, J.2
Morin, P.A.3
Saiz, R.4
Browner, W.S.5
|