Inhibition of DNA synthesis by a farnesyltransferase inhibitor involves inhibition of the p70(s6k) pathway

Journal of Biological Chemistry

Volumn 274, Issue 8, 1999, Pages 4743-4748

  Law, Brian K ^a,b   Nørgaard, Peter ^c   Gnudi, Luigi ^d   Kahn, Barbara B ^d   Poulson, Hans S ^c   Moses, Harold L ^a,b  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c FINSEN LABORATORY   (Denmark)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN FARNESYLTRANSFERASE INHIBITOR; S6 KINASE;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; DNA SYNTHESIS INHIBITION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GROWTH INHIBITION; KERATINOCYTE; MITOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN STABILITY; TARGET CELL; TRANSGENIC MOUSE;

ALKYL AND ARYL TRANSFERASES; ANIMALS; CARRIER PROTEINS; CELL DIVISION; CELL LINE; DNA REPLICATION; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; KERATINOCYTES; METHIONINE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; PHOSPHOPROTEINS; PHOSPHORYLATION; RAS PROTEINS; RIBOSOMAL PROTEIN S6 KINASES; SIROLIMUS; TUMOR CELLS, CULTURED;

ANIMALIA; MUS MUSCULUS;

EID: 0033582455     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.8.4743     Document Type: Article

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