Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition

Clinical Cancer Research

Volumn 7, Issue 6, 2001, Pages 1758-1764

  Dudkin, Lorina ^a   Dilling, Michael B ^a   Cheshire, Pamela J ^a   Harwood, Franklin C ^a   Hollingshead, Melinda ^b   Arbuck, Susan G ^c   Travis, Robert ^d   Sausville, Edward A ^b   Houghton, Peter J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b Developmental Therapeutics Program   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 4E; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN DERIVATIVE; TEMSIROLIMUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; COLON ADENOCARCINOMA; CONTROLLED STUDY; DEPHOSPHORYLATION; DISEASE MARKER; DRUG POTENCY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RHABDOMYOSARCOMA; TUMOR BIOPSY; TUMOR SUPPRESSOR GENE; TUMOR VOLUME; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOCARCINOMA; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLOTTING, WESTERN; CARRIER PROTEINS; CELL DIVISION; EUKARYOTIC INITIATION FACTOR-4E; HUMANS; IMMUNOBLOTTING; MICE; MICE, INBRED CBA; NEOPLASM TRANSPLANTATION; NEOPLASMS; PEPTIDE INITIATION FACTORS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; RHABDOMYOSARCOMA; SIROLIMUS; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0034901515     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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