Risk of advanced proximal neoplasms in asymptomatic adults according to the distal colorectal findings

New England Journal of Medicine

Volumn 343, Issue 3, 2000, Pages 169-174

  Imperiale, Thomas F ^a   Wagner, David R ^b   Lin, Ching Y ^a   Larkin, Gregory N ^c   Rogge, James D ^b   Ransohoff, David F ^d  

^a INDIANA UNIVERSITY MEDICAL CENTER   (United States)

^b Indianapolis Gastroenterology Research Foundation   (United States)

^c ELI LILLY AND COMPANY   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOMATOUS POLYP; ADULT; ADVANCED CANCER; AGE; AGED; ARTICLE; CANCER RISK; CANCER SCREENING; COLON POLYP; COLONOSCOPY; COLORECTAL CANCER; DYSPLASIA; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; SEX RATIO; VILLOUS ADENOMA;

ADENOMA; AGE FACTORS; AGED; COLONIC POLYPS; COLONOSCOPY; COLORECTAL NEOPLASMS; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREVALENCE; RISK; SEX FACTORS;

EID: 0034691750     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200007203430302     Document Type: Article

References (28)

1. Stryker SJ, Wolff BG, Culp CE, Libbe SD, Ilstrup DM, MacCarty RL. Natural history of untreated colonic polyps. Gastroenterology 1987;93: 1009-13.
2. Read TE, Read JD, Butterly LF. Importance of adenomas 5 mm or less in diameter that are detected by sigmoidoscopy. N Engl J Med 1997;336: 8-12.
3. Wallace MB, Kemp JA, Trnka YM, Donovan JM, Farraye FA. Is colonoscopy indicated for small adenomas found by screening flexible sigmoidoscopy? Ann Intern Med 1998;129:273-8.
4. Schoen RE, Corle D, Cranston L, et al. Is colonoscopy needed for the nonadvanced adenoma found on sigmoidoscopy? The Polyp Prevention Trial. Gastroenterology 1998;115:533-41.
5. Levin TR, Palitz A, Grossman S, et al. Predicting advanced proximal colonie neoplasia with screening sigmoidoscopy. JAMA 1999;281:1611-7.
6. Konishi F, Morson BC. Pathology of colorectal adenomas: a colonoscopic survey. J Clin Pathol 1982;35:830-41.
7. Rothman KJ, Greenland S. Modern epidemiology. 2nd ed. Philadelphia: Lippincott-Raven, 1998.
8. Hosmer DW Jr, Lemeshow S. Applied logistic regression. New York: John Wiley, 1989.
9. Laupacis A, Sackett DL, Roberts RS. An assessment of clinically useful measures of the consequences of treatment. N Engl J Med 1988;318:1728-33.
10. Dukes CE, Bussey HJR. The spread of rectal cancer and its effect on prognosis. Br J Cancer 1958;12:309-20.
11. Atkin WS, Morson BC, Cuzick J. Long-term risk of colorectal cancer after excision of rectosigmoid adenomas. N Engl J Med 1992;326:658-62.
12. Schoen RE, Gerber LD, Margulies C. The pathologic measurement of polyp size is preferable to the endoscopic estimate. Gastrointest Endosc 1997;46:492-6.
13. Rex DK, Lehman GA, Ulbright TM, et al. Colonic neoplasia in asymptomatic persons with negative fecal occult blood tests: influence of age, gender, and family history. Am J Gastroenterol 1993;88:825-31.
14. Johnson DA, Gurney MS, Volpe RJ, et al. A prospective study of the prevalence of colonie neoplasms in asymptomatic patients with an age-related risk. Am J Gastroenterol 1990;85:969-74.
15. Brady PG, Straker RJ, McClave SA, Nord HJ, Pinkas M, Robinson BE. Are hyperplastic rectosigmoid polyps associated with an increased risk of proximal colonie neoplasms? Gastrointest Endosc 1993;39:481-5.
16. Nusko G, Altendorf-Hofmann A, Hermanek P, Ell C, Hahn EG. Correlation of polypoid lesions in the distal colorectum and proximal colon in asymptomatic screening subjects. Eur J Gastroenterol Hepatol 1996;8:351-4.
17. Opelka FG, Timmcke AE, Gathright JB Jr, Ray JE, Hicks TC. Diminutive colonie polyps: an indication for colonoscopy. Dis Colon Rectum 1992;35:178-81.
18. Foutch PG, DiSario JA, Pardy K, Mai HD, Manne RK. The sentinel hyperplastic polyp: a marker for synchronous neoplasia in the proximal colon. Am J Gastroenterol 1991;86:1482-5.
19. Otori K, Oda Y, Sugiyama K, et al. High frequency of K-ras mutations in human colorectal hyperplastic polyps. Gut 1997;40:660-3.
20. Winawer SJ, Fletcher RH, Miller L, et al. Colorectal cancer screening: clinical guidelines and rationale. Gastroenterology 1997;112:594-642. [Errata, Gastroenterology 1997;112:1060, 1998;114:625.]
21. Bond JH. Polyp guideline: diagnosis, treatment, and surveillance for patients with no familial colorectal polyps. Ann Intern Med 1993;119:836-43. [Erratum, Ann Intern Med 1994;120:347.]
22. Davidoff F. Standing statistics right side up. Ann Intern Med 1999; 130:1019-21.
23. Tripp MR, Morgan TR, Sampliner RE, Kogan FJ, Protell RL, Earnest DL. Synchronous neoplasms in patients with diminutive colorectal adenomas. Cancer 1987;60:1599-603.
24. Papatheodoridis GV, Triantafyllou K, Tzouvala M, Paspatis G, Xourgias V, Karamanolis DG. Characteristics of rectosigmoid adenomas as predictors of synchronous advanced proximal colon neoplasms. Am J Gastroenterol 1996;91:1809-13.
25. Zarchy T, Ershoff D. Do characteristics of adenomas on flexible sigmoidoscopy predict advanced lesions on baseline colonoscopy? Gastroenterology 1994;106:1501-4.
26. Collett JA, Platell C, Fletcher DR, Aquilia S, Olynyk JK. Distal colonic neoplasms predict proximal neoplasia in average-risk, asymptomatic subjects. J Gastroenterol Hepatol 1999;14:67-71.
27. Lemmel GT, Haseman JH, Rex DK, Rahmani E. Neoplasia distal to the splenic flexure in patients with proximal colon cancer. Gastrointest Endosc 1996;44:109-11.
28. Rex DK, Chak A, Vasudeva R, et al. Prospective determination of distal colon findings in average-risk patients with proximal colon cancer. Gastrointest Endosc 1999;49:727-30.