Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas

Cancer Research

Volumn 58, Issue 21, 1998, Pages 4823-4826

  Fujita, Takeshi ^a   Matsui, Minoru ^b   Takaku, Kazuaki ^c   Uetake, Hiroyuki ^a   Ichikawa, Wataru ^a   Taketo, Makoto M ^b   Sugihara, Kenichi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; MESSENGER RNA;

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER SIZE; CLINICAL ARTICLE; COLORECTAL CARCINOMA; FEMALE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; FEMALE; HUMANS; ISOENZYMES; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 0032212487     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Rao, C. V., Rivenson, A., Simi, B., Zang, E., Kelloff, G., Steele, V., and Reddy, B. S. Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent. Cancer Res., 55: 1464-1472, 1995.
2. Waddell, W. R., Ganser, G. F., Cerise, E. J., and Loughry, R. W. Sulindac for polyposis of the colon. Am. J. Surg., 157: 175-179, 1989.
3. Giardiello, F. M., Hamilton, S. R., Krush, A. J., Piantadosi, S., Hylind, L. M., Celano, P., Booker, S. V., Robinson, C. R., and Offerhaus, G. J. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N. Engl. J. Med., 328: 1313-1316, 1993.
4. Thun, M. J., Namboodiri, M. M., and Heath, C. W., Jr. Aspirin use and reduced risk of fatal colon cancer. N. Engl. J. Med., 325: 1593-1596, 1991.
5. Smalley, W. E., and DuBois, R. N. Colorectal cancer and nonsteroidal anti-inflammatory drugs. Adv. Pharmacol., 39: 1-20, 1997.
6. Vane, J. R. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat. New Biol., 231: 232-235, 1971.
7. Miyamoto, T., Ogino, N., Yamamoto, S., and Hayaishi, O. Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. J. Biol. Chem., 251: 2629-2636, 1976.
8. Xie, W. L., Chipman, J. G., Robertson, D. L., Erikson, R. L., and Simmons, D. L. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc. Natl. Acad. Sci. USA, 88: 2692-2696, 1991.
9. Kujubu, D. A., Fletcher, B. S., Varnum, B. C., Lim, R. W., and Herschman, H. R. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J. Biol. Chem., 266: 12866-12872, 1991.
10. Eberhart, C. E., Coffey, R. J., Radhika, A., Giardiello, F. M., Ferrenbach, S., and DuBois, R. N. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology, 107: 1183-1188, 1994.
11. Sano, H., Kawahito, Y., Wilder, R. L., Hashiramoto, A., Mukai, S., Asai, K., Kimura, S., Kato, H., Kondo, M., and Hla, T. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res., 55: 3785-3789, 1995.
12. Kargman, S. L., O'Neill, G. P., Vickers, P. J., Evans, J. F., Mancini, J. A., and Jothy, S. Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res., 55; 2556-2559, 1995.
13. δ716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell, 87: 803-809, 1996.
14. Yang, V. W., Shields, J. M., Hamilton, S. R., Spannhake, E. W., Hubbard, W. C., Hylind, L. M., Robinson, C. R., and Giardiello, F. M, Size-dependent increase in prostanoid levels in adenomas of patients with familial adenomatous polyposis. Cancer Res., 58: 1750-1753, 1998.
15. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem., 162: 156-159, 1987.
16. Freemantle, S. J., Jackman, A. L., Kelland, L. R., Calvert, A. H., and Lunec, J. Molecular characterization of two cell lines selected for resistance to the folate-based thymidylate synthase inhibitor, ZD1694. Br. J. Cancer, 71: 925-930, 1995.
17. DuBois, R. N., Radhika, A., Reddy, B. S., and Entingh, A. J. Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterology, 110: 1259-1262, 1996.
18. International Union Against Cancer. Colon and Rectum. In: L. H. Sobin and C. Wittekind (eds.), TNM Classification of Malignant Tumors, Ed. 5 pp. 66-69. New York: Wiley-Liss. Inc., 1997.
19. Wolmark, N., Cruz, I., Redmond, C. K., Fisher, B., and Fisher, E. R. Tumor size and regional lymph node metastasis in colorectal cancer. A preliminary analysis from the NSABP clinical trials. Cancer (Phila.), 51: 1315-1322, 1983.
20. Morson, B. President's address. The polyp-cancer sequence in the large bowel. Proc. R. Soc. Med., 67: 451-457, 1974.
21. Sandier, R. S., Galanko, J. C., Murray, S. C., Helm, J. F., and Woosley, J. T. Aspirin and non-steroidal anti-inflammatory agents and risk for colorectal adenomas. Gastroenterology, 114: 441-447, 1998.
22. Matsuhashi, N., Nakajima, A., Fukushima, Y., Yazaki, Y., and Oka, T. Effects of sulindac on sporadic colorectal adenomatous polyps. Gut, 40: 344-349, 1997.
23. Nakajima, T., Hamanaka, K., Fukuda, T., Oyama, T., Kashiwabara, K., and Sano, T. Why is cyclooxygenase-2 expressed in neuroendocrine cells of the human alimentary tract? Pathol. Int., 47: 889-891, 1997.
24. Prescott, S. M., and White, R. L. Self-promotion? Intimate connections between APC and prostaglandin H synthase-2. Cell, 87: 783-786, 1996.