메뉴 건너뛰기




Volumn 63, Issue 11, 2002, Pages 1512-1519

Effects of an adenosine kinase inhibitor and an adenosine deaminase inhibitor on accumulation of extracellular adenosine by equine articular chondrocytes

Author keywords

[No Author keywords available]

Indexed keywords

5' IODOTUBERCIDIN; 9 (2 HYDROXY 3 NONYL)ADENINE; ADENOSINE; ADENOSINE DEAMINASE INHIBITOR; ADENOSINE KINASE INHIBITOR; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; NITRIC OXIDE; UNCLASSIFIED DRUG;

EID: 0036847461     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2002.63.1512     Document Type: Article
Times cited : (25)

References (51)
  • 1
    • 0030459187 scopus 로고    scopus 로고
    • Inflammatory joint disease: The role of cytokines, cyclooxygenases and reactive oxygen species
    • Moulton PJ. Inflammatory joint disease: the role of cytokines, cyclooxygenases and reactive oxygen species. Br J Biomed Sci 1996;53:317-324.
    • (1996) Br. J. Biomed. Sci , vol.53 , pp. 317-324
    • Moulton, P.J.1
  • 2
    • 0036155942 scopus 로고    scopus 로고
    • Osteoarthritis or osteoarthrosis: The definition of inflammation becomes a semantic issue in the genomic era of molecular medicine
    • Attur MG, Dave M, Akamatsu M, et al. Osteoarthritis or osteoarthrosis: the definition of inflammation becomes a semantic issue in the genomic era of molecular medicine. Osteoarthritis Cartilage 2002;10:1-4.
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 1-4
    • Attur, M.G.1    Dave, M.2    Akamatsu, M.3
  • 3
    • 0028798575 scopus 로고
    • Inhibition of neutrophil adhesion by adenosine and an adenosine kinase inhibitor. The role of selectins
    • Firestein GS, Bullough DA, Erion MD, et al. Inhibition of neutrophil adhesion by adenosine and an adenosine kinase inhibitor. The role of selectins. J Immunol 1995;154:326-334.
    • (1995) J. Immunol , vol.154 , pp. 326-334
    • Firestein, G.S.1    Bullough, D.A.2    Erion, M.D.3
  • 5
    • 0020554177 scopus 로고
    • Adenosine: A physiological modulator of superoxide anion generation by human neutrophils
    • Cronstein BN, Kramer SB, Weissmann G, et al. Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. J Exp Med 1983;158:1160-1177.
    • (1983) J. Exp. Med , vol.158 , pp. 1160-1177
    • Cronstein, B.N.1    Kramer, S.B.2    Weissmann, G.3
  • 6
    • 0032547817 scopus 로고    scopus 로고
    • Neutrophil-derived 5′-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation
    • Lennon PF, Taylor CT, Stahl GL, et al. Neutrophil-derived 5′-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation. J Exp Med 1998;188:1433-1443.
    • (1998) J. Exp. Med , vol.188 , pp. 1433-1443
    • Lennon, P.F.1    Taylor, C.T.2    Stahl, G.L.3
  • 7
    • 0025184251 scopus 로고
    • The antiinflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats
    • Schrier DJ, Lesch ME, Wright CD, et al. The antiinflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats. J Immunol 1990;145:1874-1879.
    • (1990) J. Immunol , vol.145 , pp. 1874-1879
    • Schrier, D.J.1    Lesch, M.E.2    Wright, C.D.3
  • 8
    • 0031691973 scopus 로고    scopus 로고
    • Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists
    • Szabo C, Scott GS, Virag L, et al. Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists. Br J Pharmacol 1998;125:379-387.
    • (1998) Br. J. Pharmacol , vol.125 , pp. 379-387
    • Szabo, C.1    Scott, G.S.2    Virag, L.3
  • 9
    • 0027154950 scopus 로고
    • Inhibition of human monocyte TNF production by adenosine receptor agonists
    • Le Vraux V, Chen YL, Masson I, et al. Inhibition of human monocyte TNF production by adenosine receptor agonists. Life Sci 1993;52:1917-1924.
    • (1993) Life Sci , vol.52 , pp. 1917-1924
    • Le Vraux, V.1    Chen, Y.L.2    Masson, I.3
  • 10
    • 0030588630 scopus 로고    scopus 로고
    • Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice
    • Hasko G, Szabo C, Nemeth ZH, et al. Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J Immunol 1996;157:4634-4640.
    • (1996) J. Immunol , vol.157 , pp. 4634-4640
    • Hasko, G.1    Szabo, C.2    Nemeth, Z.H.3
  • 11
  • 13
    • 0031936693 scopus 로고    scopus 로고
    • 2 release from human rheumatoid synovial cells
    • 2 release from human rheumatoid synovial cells. Arthritis Rheum 1998;41:246-255.
    • (1998) Arthritis Rheum , vol.41 , pp. 246-255
    • Loredo, G.A.1    Benton, H.P.2
  • 14
    • 0029896521 scopus 로고    scopus 로고
    • Inhibition of synoviocyte collagenase gene expression by adenosine receptor stimulation
    • Boyle DL, Fereydoun GS, Firestein GS. Inhibition of synoviocyte collagenase gene expression by adenosine receptor stimulation. Arthritis Rheum 1996;39:923-930.
    • (1996) Arthritis Rheum , vol.39 , pp. 923-930
    • Boyle, D.L.1    Fereydoun, G.S.2    Firestein, G.S.3
  • 15
    • 0035046976 scopus 로고    scopus 로고
    • Extracellular nucleotide signaling: A mechanism for integrating local and systemic responses in the activation of bone remodeling
    • Bowler WB, Buckley KA, Gartland A, et al. Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling. Bone 2001;28:507-512.
    • (2001) Bone , vol.28 , pp. 507-512
    • Bowler, W.B.1    Buckley, K.A.2    Gartland, A.3
  • 16
    • 85047678432 scopus 로고
    • Cloned receptors and cardiovascular responses to adenosine
    • Tucker AL, Linden J. Cloned receptors and cardiovascular responses to adenosine. Cardiovasc Res 1993;27:62-67.
    • (1993) Cardiovasc. Res , vol.27 , pp. 62-67
    • Tucker, A.L.1    Linden, J.2
  • 17
    • 0036486653 scopus 로고    scopus 로고
    • Effects of adenosine on bacterial lipopolysaccharide- and interleukin 1-induced nitric oxide release from equine articular chondrocytes
    • Benton HP, MacDonald MH, Tesch AM. Effects of adenosine on bacterial lipopolysaccharide- and interleukin 1-induced nitric oxide release from equine articular chondrocytes. Am J Vet Res 2002; 63:204-210.
    • (2002) Am. J. Vet. Res , vol.63 , pp. 204-210
    • Benton, H.P.1    MacDonald, M.H.2    Tesch, A.M.3
  • 18
    • 0036153642 scopus 로고    scopus 로고
    • 2 receptors and activity is potentiated by an adenosine deaminase inhibitor and a phosphodiesterase inhibitor
    • 2 receptors and activity is potentiated by an adenosine deaminase inhibitor and a phosphodiesterase inhibitor. Osteoarthritis Cartilage 2002;10:34-43.
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 34-43
    • Tesch, A.M.1    MacDonald, M.H.2    Kollias-Baker, C.3
  • 19
    • 0015944892 scopus 로고
    • Enzyme inhibitors. 26. Bridging hydrophobic and hydrophilic regions on adenosine deaminase with some 9-(2-hydroxy-3-alkyl)adenines
    • Schaeffer HJ, Schwender CF. Enzyme inhibitors. 26. Bridging hydrophobic and hydrophilic regions on adenosine deaminase with some 9-(2-hydroxy-3-alkyl)adenines. J Med Chem 1974;17:6-8.
    • (1974) J. Med. Chem , vol.17 , pp. 6-8
    • Schaeffer, H.J.1    Schwender, C.F.2
  • 20
    • 0034721142 scopus 로고    scopus 로고
    • Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues
    • Ugarkar BG, Castellino AJ, DaRe JM, et al. Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues. J Med Chem 2000;43:2894-2905.
    • (2000) J. Med. Chem , vol.43 , pp. 2894-2905
    • Ugarkar, B.G.1    Castellino, A.J.2    DaRe, J.M.3
  • 21
  • 22
    • 0034721186 scopus 로고    scopus 로고
    • Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodombercidin analogues
    • Ugarkar BG, DaRe JM, Kopcho JJ, et al. Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodombercidin analogues. J Med Chem 2000;43:2883-2893.
    • (2000) J. Med. Chem , vol.43 , pp. 2883-2893
    • Ugarkar, B.G.1    DaRe, J.M.2    Kopcho, J.J.3
  • 23
    • 0029069956 scopus 로고
    • Anti-inflamamatory effects of an adenosine kinase inhibitor. Decreased neutrophil accumulation and vascular leakage
    • Rosengren S, Bong GW, Firestein GS. Anti-inflamamatory effects of an adenosine kinase inhibitor. Decreased neutrophil accumulation and vascular leakage. J Immunol 1995;154:5444-5451.
    • (1995) J. Immunol , vol.154 , pp. 5444-5451
    • Rosengren, S.1    Bong, G.W.2    Firestein, G.S.3
  • 24
    • 0033697042 scopus 로고    scopus 로고
    • ABT-702 (4-amino-5-(3-bromophenyl) - 7- (6-morpholino-pyriclin -3 -yl)pyrido [2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties. II. In vivo characterization in the rat
    • Kowaluk EA, Mikusa J, Wismer CT, et al. ABT-702 (4-amino-5-(3-bromophenyl) - 7- (6-morpholino-pyriclin -3 -yl)pyrido [2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties. II. In vivo characterization in the rat. J Pharmacol Exp Ther 2000;295:1165-1174.
    • (2000) J. Pharmacol. Exp. Ther , vol.295 , pp. 1165-1174
    • Kowaluk, E.A.1    Mikusa, J.2    Wismer, C.T.3
  • 25
    • 0029118909 scopus 로고
    • The antiinflammatory effects of an adenosine kinase inhibitor are mediated by adenosine
    • Cronstein BN, Naime D, Firestein G. The antiinflammatory effects of an adenosine kinase inhibitor are mediated by adenosine. Arthritis Rheum 1995;38:1040-1045.
    • (1995) Arthritis Rheum , vol.38 , pp. 1040-1045
    • Cronstein, B.N.1    Naime, D.2    Firestein, G.3
  • 26
    • 0035146599 scopus 로고    scopus 로고
    • Effects of A-134974, a novel adenosine kinase inhibitor, on carrageenan-induced inflammatory hyperalgesia and locomotor activity in rats: Evaluation of the sites of action
    • McGaraughty S, Chu KL, Wismer CT, et al. Effects of A-134974, a novel adenosine kinase inhibitor, on carrageenan-induced inflammatory hyperalgesia and locomotor activity in rats: evaluation of the sites of action. J Pharmacol Exp Ther 2001;296:501-509.
    • (2001) J. Pharmacol. Exp. Ther , vol.296 , pp. 501-509
    • McGaraughty, S.1    Chu, K.L.2    Wismer, C.T.3
  • 27
    • 0035141231 scopus 로고    scopus 로고
    • Anti-inflammatory effects of ABT-702, a novel non-nucleoside adenosine kinase inhibitor, in rat adjuvant arthritis
    • Boyle DL, Kowaluk EA, Jarvis MF, et al. Anti-inflammatory effects of ABT-702, a novel non-nucleoside adenosine kinase inhibitor, in rat adjuvant arthritis. J Pharmacol Exp Ther 2001;296:495-500.
    • (2001) J. Pharmacol. Exp. Ther , vol.296 , pp. 495-500
    • Boyle, D.L.1    Kowaluk, E.A.2    Jarvis, M.F.3
  • 28
    • 0027064521 scopus 로고
    • Regulation of matrix metabolism in equine cartilage explant cultures by interleukin 1
    • MacDonald MH, Stover SM, Willits NH, et al. Regulation of matrix metabolism in equine cartilage explant cultures by interleukin 1. Am J Vet Res 1992;53:2278-2285.
    • (1992) Am. J. Vet. Res , vol.53 , pp. 2278-2285
    • MacDonald, M.H.1    Stover, S.M.2    Willits, N.H.3
  • 29
    • 0031597235 scopus 로고    scopus 로고
    • Adenosine 5′-triphosphate, uridine 5′-triphosphate, bradykinin, and lysopbosphatidic acid induce different patterns of calcium responses by human articular chondrocytes
    • Koolpe M, Rodrigo JJ, Benton HP. Adenosine 5′-triphosphate, uridine 5′-triphosphate, bradykinin, and lysopbosphatidic acid induce different patterns of calcium responses by human articular chondrocytes. J Orthop Res 1998;16:217-226.
    • (1998) J. Orthop. Res , vol.16 , pp. 217-226
    • Koolpe, M.1    Rodrigo, J.J.2    Benton, H.P.3
  • 30
    • 0036003325 scopus 로고    scopus 로고
    • Characterization of age and location associated variations in the composition of articular cartilage from the equine metacarpophalangeal joint
    • MacDonald MH, Tesch AM, Benton HP, et al. Characterization of age and location associated variations in the composition of articular cartilage from the equine metacarpophalangeal joint. J Equine Vet Sci 2002;22:25-32.
    • (2002) J. Equine Vet. Sci , vol.22 , pp. 25-32
    • MacDonald, M.H.1    Tesch, A.M.2    Benton, H.P.3
  • 31
    • 0024356008 scopus 로고
    • Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay
    • Plumb JA, Milroy R, Kaye SB. Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay. Cancer Res 1989;49:4435-4440.
    • (1989) Cancer Res , vol.49 , pp. 4435-4440
    • Plumb, J.A.1    Milroy, R.2    Kaye, S.B.3
  • 32
    • 0020448709 scopus 로고
    • Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids
    • Green LC, Wagner DA, Glogowski J, et al. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 1982;126:131-138.
    • (1982) Anal. Biochem , vol.126 , pp. 131-138
    • Green, L.C.1    Wagner, D.A.2    Glogowski, J.3
  • 33
    • 0025721956 scopus 로고
    • Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide
    • Stadler J, Stefanovic-Racic M, Billiar TR, et al. Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide. J Immunol 1991;147:3915-3920.
    • (1991) J. Immunol , vol.147 , pp. 3915-3920
    • Stadler, J.1    Stefanovic-Racic, M.2    Billiar, T.R.3
  • 34
    • 0030025492 scopus 로고    scopus 로고
    • The role of nitric oxide in proteoglycan turnover by bovine articular cartilage organ cultures
    • Stefanovic-Racic M, Morales TI, Taskiran D, et al. The role of nitric oxide in proteoglycan turnover by bovine articular cartilage organ cultures. J Immunol 1996,156:1213-1220.
    • (1996) J. Immunol , vol.156 , pp. 1213-1220
    • Stefanovic-Racic, M.1    Morales, T.I.2    Taskiran, D.3
  • 35
    • 0024590802 scopus 로고
    • Fluorophotometric quantitation of DNA in articular cartilage utilizing Hoechst 33258
    • Lipman JM. Fluorophotometric quantitation of DNA in articular cartilage utilizing Hoechst 33258. Anal Biochem 1989;176:128-131.
    • (1989) Anal. Biochem , vol.176 , pp. 128-131
    • Lipman, J.M.1
  • 36
    • 0032518281 scopus 로고    scopus 로고
    • Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5′-nucleotidase-mediated conversion of adenine nucleotides
    • Morabito L, Montesinos MC, Schreibman DM, et al. Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5′-nucleotidase-mediated conversion of adenine nucleotides. J Clin Invest 1998;101:295-300.
    • (1998) J. Clin. Invest , vol.101 , pp. 295-300
    • Morabito, L.1    Montesinos, M.C.2    Schreibman, D.M.3
  • 37
    • 0034923094 scopus 로고    scopus 로고
    • The role and regulation of adenosine in the central nervous system
    • Dunwiddie TV, Masino SA. The role and regulation of adenosine in the central nervous system. Annu Rev Neurosci 2001;24:31-55.
    • (2001) Annu. Rev. Neurosci , vol.24 , pp. 31-55
    • Dunwiddie, T.V.1    Masino, S.A.2
  • 38
    • 0031914926 scopus 로고    scopus 로고
    • Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat
    • Poon A, Sawynok J. Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat. Pain 1998;74:235-245.
    • (1998) Pain , vol.74 , pp. 235-245
    • Poon, A.1    Sawynok, J.2
  • 39
    • 0025911261 scopus 로고
    • Extracellular levels of adenosine and its metabolites in the striatum of awake rats: Inhibition of uptake and metabolism
    • Ballarin M, Fredholm BB, Ambrosio S, et al. Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism. Acta Physiol Scand 1991;142:97-103.
    • (1991) Acta Physiol. Scand , vol.142 , pp. 97-103
    • Ballarin, M.1    Fredholm, B.B.2    Ambrosio, S.3
  • 40
    • 0027935403 scopus 로고
    • Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices
    • Pak MA, Haas HL, Decking UK, et al. Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices. Neuropharmacology 1994;33:1049-1053.
    • (1994) Neuropharmacology , vol.33 , pp. 1049-1053
    • Pak, M.A.1    Haas, H.L.2    Decking, U.K.3
  • 41
    • 0028172348 scopus 로고
    • Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions
    • Zhu PJ, Krnjevic K. Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions. Neuroscience 1994;62:489-497.
    • (1994) Neuroscience , vol.62 , pp. 489-497
    • Zhu, P.J.1    Krnjevic, K.2
  • 42
    • 0033922520 scopus 로고    scopus 로고
    • ATP release by mechanically loaded porcine chondrons in pellet culture
    • Graff RD, Lazarowski ER, Banes AJ, et al. ATP release by mechanically loaded porcine chondrons in pellet culture. Arthritis Rheum 2000;43:1571-1579.
    • (2000) Arthritis Rheum , vol.43 , pp. 1571-1579
    • Graff, R.D.1    Lazarowski, E.R.2    Banes, A.J.3
  • 43
  • 47
    • 2642661478 scopus 로고    scopus 로고
    • Differences in nitric oxide production by superficial and deep human articular chondrocytes: Implications for proteoglycan turnover in inflammatory joint diseases
    • Hauselmann HJ, Stefanovic-Racic M, Michel BA, et al Differences in nitric oxide production by superficial and deep human articular chondrocytes: implications for proteoglycan turnover in inflammatory joint diseases. J Immunol 1998;160:1444-1448.
    • (1998) J. Immunol , vol.160 , pp. 1444-1448
    • Hauselmann, H.J.1    Stefanovic-Racic, M.2    Michel, B.A.3
  • 48
    • 0033939459 scopus 로고    scopus 로고
    • Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization
    • Johnson K, Jung A, Murphy A, et al. Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis Rheum 2000;43:1560-1570.
    • (2000) Arthritis Rheum , vol.43 , pp. 1560-1570
    • Johnson, K.1    Jung, A.2    Murphy, A.3
  • 49
    • 0035150360 scopus 로고    scopus 로고
    • Nitric oxide regulates mitochondrial respiration and functions of articular chondrocytes
    • Tomita M, Sato EF, Nishikawa M, et al. Nitric oxide regulates mitochondrial respiration and functions of articular chondrocytes. Arthritis Rheum 2001;44:96-104.
    • (2001) Arthritis Rheum , vol.44 , pp. 96-104
    • Tomita, M.1    Sato, E.F.2    Nishikawa, M.3
  • 50
    • 0029985232 scopus 로고    scopus 로고
    • Nitric oxide production in cells derived from the human joint
    • Grabowski PS, Macpherson H, Ralston SH. Nitric oxide production in cells derived from the human joint. Br J Rheumatol 1996;35:207-212.
    • (1996) Br. J. Rheumatol , vol.35 , pp. 207-212
    • Grabowski, P.S.1    Macpherson, H.2    Ralston, S.H.3
  • 51
    • 0031093312 scopus 로고    scopus 로고
    • Nitric oxide production by equine articular cells in vitro
    • Frean SP, Bryant CE, Froling IL, et al. Nitric oxide production by equine articular cells in vitro. Equine Vet J 1997;29:98-102.
    • (1997) Equine Vet. J , vol.29 , pp. 98-102
    • Frean, S.P.1    Bryant, C.E.2    Froling, I.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.