Anti-inflammatory effects of ABT-702, a novel non-nucleoside adenosine kinase inhibitor, in rat adjuvant arthritis

Journal of Pharmacology and Experimental Therapeutics

Volumn 296, Issue 2, 2001, Pages 495-500

  Boyle, David L ^a   Kowaluk, Elizabeth A ^b   Jarvis, Michael F ^b   Lee, Chih Hung ^b   Bhagwat, Shripad S ^b,c   Williams, Michael ^b   Firestein, Gary S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ABBOTT LABORATORIES   (United States)

^c CELGENE CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABT 702; ADENOSINE KINASE; ADENOSINE KINASE INHIBITOR; ADENOSINE RECEPTOR; ANTIINFLAMMATORY AGENT; COLLAGENASE 3; CP 515; FREUND ADJUVANT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; STROMELYSIN; THEOPHYLLINE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; DRUG INHIBITION; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; MALE; NONHUMAN; NUCLEOTIDE METABOLISM; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SYNOVIUM; TRANSCRIPTION REGULATION;

ADENOSINE; ADENOSINE KINASE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, EXPERIMENTAL; BIOTRANSFORMATION; BLOTTING, NORTHERN; BONE AND BONES; CELL NUCLEUS; ENZYME INHIBITORS; FREUND'S ADJUVANT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INDICATORS AND REAGENTS; MALE; MATRIX METALLOPROTEINASES; MORPHOLINES; PYRIMIDINES; RATS; RATS, INBRED LEW;

EID: 0035141231     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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