Effects of A-134974, a novel adenosine kinase inhibitor, on carrageenan-induced inflammatory hyperalgesia and locomotor activity in rats: Evaluation of the sites of action

Journal of Pharmacology and Experimental Therapeutics

Volumn 296, Issue 2, 2001, Pages 501-509

  Mcgaraughty, Steve ^a   Chu, Katharine L ^a   Wismer, Carol T ^a   Mikusa, Joe ^a   Zhu, Chang Z ^a   Cowart, Marlon ^a   Kowaluk, Elizabeth A ^a   Jarvis, Michael F ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 ANILINO 5 PHENYLPYRROLO[2,3 D]PYRIMIDINE 7 (5 DEOXYRIBOSIDE); 5 IODOTUBERCIDIN; 5' AMINO 5' DEOXYADENOSINE; 5' DEOXY 5 IODOTUBERCIDIN; A 134974; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE KINASE INHIBITOR; ANTINOCICEPTIVE AGENT; CARRAGEENAN; CYCLOHEXYLADENOSINE; MORPHINE; THEOPHYLLINE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG POTENCY; HUMAN; HUMAN CELL; HYPERALGESIA; INFLAMMATION; LOCOMOTION; MALE; NEUROBLASTOMA CELL; NEUROMODULATION; NONHUMAN; PATHOPHYSIOLOGY; PAW EDEMA; PRIORITY JOURNAL; RAT;

ADENOSINE KINASE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; CENTRAL NERVOUS SYSTEM; ENZYME INHIBITORS; HYPERALGESIA; INFLAMMATION; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; MALE; MOTOR ACTIVITY; NUCLEOSIDES; PERIPHERAL NERVOUS SYSTEM; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD;

EID: 0035146599     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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