Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues

Journal of Medicinal Chemistry

Volumn 43, Issue 15, 2000, Pages 2894-2905

  Ugarkar, Bheemarao G ^a   Castellino, Angelo J ^a   DaRe, Jay M ^a   Kopcho, Joseph J ^a   Wiesner, James B ^a   Schanzer, Juergen M ^a   Erion, Mark D ^a  

^a Metabasis Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 IODOTUBERCIDIN; ADENOSINE KINASE INHIBITOR; TUBERCIDIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; GLYCOSYLATION; MALE; NONHUMAN; RAT; REACTION ANALYSIS; SEIZURE; STEREOCHEMISTRY;

ADENOSINE KINASE; ANIMALS; ANTICONVULSANTS; ENZYME INHIBITORS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; RATS; RECOMBINANT PROTEINS; SEIZURES; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; TUBERCIDIN;

EID: 0034721142     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0000259     Document Type: Article

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