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Volumn 143, Issue 10, 2002, Pages 3802-3812

Activation of phosphatidylinositol 3-kinase contributes to insulin-like growth factor I-mediated inhibition of pancreatic β-cell death

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ADENOVIRUS VECTOR; BOVINE SERUM ALBUMIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; GLYCOGEN SYNTHASE KINASE 3BETA; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN KINASE B; S6 KINASE; SOMATOMEDIN C;

EID: 0036772979     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220058     Document Type: Article
Times cited : (60)

References (62)
  • 1
    • 0021885905 scopus 로고
    • Neonatal rat islet cell cultures synthesize insulin-like growth factor I
    • Romanus JA, Rabinovitch A, Rechler MM 1985 Neonatal rat islet cell cultures synthesize insulin-like growth factor I. Diabetes 34:696-702
    • (1985) Diabetes , vol.34 , pp. 696-702
    • Romanus, J.A.1    Rabinovitch, A.2    Rechler, M.M.3
  • 2
    • 0028100703 scopus 로고
    • The ontogeny of insulin-like growth factor (IGF) and IGF-binding protein gene expression in the rat pancreas
    • Hogg J, Hill DJ, Han VK 1994 The ontogeny of insulin-like growth factor (IGF) and IGF-binding protein gene expression in the rat pancreas. J Mol Endocrinol 13:49-58
    • (1994) J Mol Endocrinol , vol.13 , pp. 49-58
    • Hogg, J.1    Hill, D.J.2    Han, V.K.3
  • 3
    • 0023582853 scopus 로고
    • Somatomedin-C in human fetal pancreas. Cellular localization and release during organ culture
    • Hill DJ, Frazer A, Swenne I, Wirdnam PK, Milner RD 1987 Somatomedin-C in human fetal pancreas. Cellular localization and release during organ culture. Diabetes 36:465-471
    • (1987) Diabetes , vol.36 , pp. 465-471
    • Hill, D.J.1    Frazer, A.2    Swenne, I.3    Wirdnam, P.K.4    Milner, R.D.5
  • 4
    • 0033012057 scopus 로고    scopus 로고
    • Cellular distribution and ontogeny of insulin-like growth factors (IGFs) and IGF binding protein messenger RNAs and peptides in developing rat pancreas
    • Hill DJ, Hogg J, Petrik J, Arany E, Han VK 1999 Cellular distribution and ontogeny of insulin-like growth factors (IGFs) and IGF binding protein messenger RNAs and peptides in developing rat pancreas. J Endocrinol 160:305-317
    • (1999) J Endocrinol , vol.160 , pp. 305-317
    • Hill, D.J.1    Hogg, J.2    Petrik, J.3    Arany, E.4    Han, V.K.5
  • 5
    • 0034130454 scopus 로고    scopus 로고
    • IGF-I and GH post-receptor signaling mechanisms for pancreatic β-cell replication
    • Rhodes CJ 2000 IGF-I and GH post-receptor signaling mechanisms for pancreatic β-cell replication. J Mol Endocrinol 24:303-311
    • (2000) J Mol Endocrinol , vol.24 , pp. 303-311
    • Rhodes, C.J.1
  • 7
    • 0032841435 scopus 로고    scopus 로고
    • Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signalling
    • Withers DJ, Burks DJ, Towery HH, Altamuro SL, Flint CL, White MF 1999 Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signalling. Nat Genet 23:32-40
    • (1999) Nat Genet , vol.23 , pp. 32-40
    • Withers, D.J.1    Burks, D.J.2    Towery, H.H.3    Altamuro, S.L.4    Flint, C.L.5    White, M.F.6
  • 9
    • 0031788728 scopus 로고    scopus 로고
    • Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may act as a survival factor
    • Petrik J, Arany E, McDonald TJ, Hill DJ 1998 Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may act as a survival factor. Endocrinology 139:2994-3004
    • (1998) Endocrinology , vol.139 , pp. 2994-3004
    • Petrik, J.1    Arany, E.2    McDonald, T.J.3    Hill, D.J.4
  • 10
    • 0034703640 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signaling to Akt mediates survival in isolated canine islets of Langerhans
    • Aikin R, Rosenberg L, Maysinger D 2000 Phosphatidylinositol 3-kinase signaling to Akt mediates survival in isolated canine islets of Langerhans. Biochem Biophys Res Commun 277:455-461
    • (2000) Biochem Biophys Res Commun , vol.277 , pp. 455-461
    • Aikin, R.1    Rosenberg, L.2    Maysinger, D.3
  • 11
    • 0033969128 scopus 로고    scopus 로고
    • Inhibitory effect of IGF-I on type 2 nitric oxide synthase expression in Ins-1 cells and protection against activation-dependent apoptosis: Involvement of phosphatidylinositol 3-kinase
    • Castrillo A, Bodelon OG, Bosca L 2000 Inhibitory effect of IGF-I on type 2 nitric oxide synthase expression in Ins-1 cells and protection against activation-dependent apoptosis: Involvement of phosphatidylinositol 3-kinase. Diabetes 49:209-217
    • (2000) Diabetes , vol.49 , pp. 209-217
    • Castrillo, A.1    Bodelon, O.G.2    Bosca, L.3
  • 12
    • 0034509569 scopus 로고    scopus 로고
    • Prevention of β cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I
    • Giannoukakis N, Mi Z, Rudert WA, Gambotto A, Trucco M, Robbins P 2000 Prevention of β cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I. Gene Ther 7:2015-2022
    • (2000) Gene Ther , vol.7 , pp. 2015-2022
    • Giannoukakis, N.1    Mi, Z.2    Rudert, W.A.3    Gambotto, A.4    Trucco, M.5    Robbins, P.6
  • 13
    • 0345222443 scopus 로고    scopus 로고
    • Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice
    • Hill DJ, Petrik J, Arany E, McDonald TJ, Delovitch TL 1999 Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice. J Endocrinol 161:153-165
    • (1999) J Endocrinol , vol.161 , pp. 153-165
    • Hill, D.J.1    Petrik, J.2    Arany, E.3    McDonald, T.J.4    Delovitch, T.L.5
  • 14
    • 0032544722 scopus 로고    scopus 로고
    • Growth factor protection against cytokine-induced apoptosis in neonatal rat islets of Langerhans: Role of Fas
    • Harrison M, Dunger AM, Berg S, Mabley J, John N, Green MH, Green IC 1998 Growth factor protection against cytokine-induced apoptosis in neonatal rat islets of Langerhans: Role of Fas. FEBS Lett 435:207-210
    • (1998) FEBS Lett , vol.435 , pp. 207-210
    • Harrison, M.1    Dunger, A.M.2    Berg, S.3    Mabley, J.4    John, N.5    Green, M.H.6    Green, I.C.7
  • 15
    • 0030730904 scopus 로고    scopus 로고
    • Insulin-like growth factor I reverses interleukin-1β inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of Langerhans
    • Mabley JG, Belin V, John N, Green IC 1997 Insulin-like growth factor I reverses interleukin-1β inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of Langerhans. FEBS Lett 417:235-238
    • (1997) FEBS Lett , vol.417 , pp. 235-238
    • Mabley, J.G.1    Belin, V.2    John, N.3    Green, I.C.4
  • 20
    • 0036097472 scopus 로고    scopus 로고
    • β-cell death and mass in syngeneically transplanted islets exposed to short-and long-term hyperglycemia
    • Biarnes M, Montolio M, Nacher V, Raurell M, Soler J, Montanya E 2002 β-cell death and mass in syngeneically transplanted islets exposed to short-and long-term hyperglycemia. Diabetes 51:66-72
    • (2002) Diabetes , vol.51 , pp. 66-72
    • Biarnes, M.1    Montolio, M.2    Nacher, V.3    Raurell, M.4    Soler, J.5    Montanya, E.6
  • 21
    • 0029821899 scopus 로고    scopus 로고
    • Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function
    • Davalli AM, Scaglia L, Zangen DH, Hollister J, Bonner-Weir S, Weir GC 1996 Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes 45:1161-1167
    • (1996) Diabetes , vol.45 , pp. 1161-1167
    • Davalli, A.M.1    Scaglia, L.2    Zangen, D.H.3    Hollister, J.4    Bonner-Weir, S.5    Weir, G.C.6
  • 22
    • 0026550830 scopus 로고
    • Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines
    • Asfari M, Janjic D, Meda P, Li G, Halban PA, Wollheim CB 1992 Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 130:167-178
    • (1992) Endocrinology , vol.130 , pp. 167-178
    • Asfari, M.1    Janjic, D.2    Meda, P.3    Li, G.4    Halban, P.A.5    Wollheim, C.B.6
  • 23
    • 0025281303 scopus 로고
    • Establishment of a pancreatic β cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms
    • Miyazaki J, Araki K, Yamato E, Ikegami H, Asano T, Shibasaki Y, Oka Y, Yamamura K 1990 Establishment of a pancreatic β cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms. Endocrinology 127:126-132
    • (1990) Endocrinology , vol.127 , pp. 126-132
    • Miyazaki, J.1    Araki, K.2    Yamato, E.3    Ikegami, H.4    Asano, T.5    Shibasaki, Y.6    Oka, Y.7    Yamamura, K.8
  • 25
    • 0032979226 scopus 로고    scopus 로고
    • Targeted expression of toxic genes directed by pituitary hormone promoters: A potential strategy for adenovirus-mediated gene therapy of pituitary tumors
    • Lee EJ, Anderson LM, Thimmapaya B, Jameson JL 1999 Targeted expression of toxic genes directed by pituitary hormone promoters: A potential strategy for adenovirus-mediated gene therapy of pituitary tumors. J Clin Endocrinol Metab 84:786-794
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 786-794
    • Lee, E.J.1    Anderson, L.M.2    Thimmapaya, B.3    Jameson, J.L.4
  • 26
    • 0035043126 scopus 로고    scopus 로고
    • The role of phosphatidylinositol 3-kinase and the mitogen-activated protein kinases in insulin-like growth factor-I-mediated effects in vascular endothelial cells
    • Liu W, Liu Y, Lowe Jr WL 2001 The role of phosphatidylinositol 3-kinase and the mitogen-activated protein kinases in insulin-like growth factor-I-mediated effects in vascular endothelial cells. Endocrinology 142:1710-1719
    • (2001) Endocrinology , vol.142 , pp. 1710-1719
    • Liu, W.1    Liu, Y.2    Lowe W.L., Jr.3
  • 27
    • 0028802385 scopus 로고
    • The major promoter of the rat insulin-like growth factor-I gene binds a protein complex that is required for basal expression
    • An MR, Lowe Jr WL 1995 The major promoter of the rat insulin-like growth factor-I gene binds a protein complex that is required for basal expression. Mol Cell Endocrinol 114:77-89
    • (1995) Mol Cell Endocrinol , vol.114 , pp. 77-89
    • An, M.R.1    Lowe W.L., Jr.2
  • 28
    • 0031770827 scopus 로고    scopus 로고
    • Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I
    • Kulik G, Weber MJ 1998 Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I. Mol Cell Biol 18:6711-6718
    • (1998) Mol Cell Biol , vol.18 , pp. 6711-6718
    • Kulik, G.1    Weber, M.J.2
  • 29
    • 0031014651 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways
    • Parrizas M, Saltiel AR, LeRoith D 1997 Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways. J Biol Chem 272:154-161
    • (1997) J Biol Chem , vol.272 , pp. 154-161
    • Parrizas, M.1    Saltiel, A.R.2    LeRoith, D.3
  • 31
    • 0032504211 scopus 로고    scopus 로고
    • Insulin-like growth factor I (IGF-I)-stimulated pancreatic β-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells
    • Hugl SR, White MF, Rhodes CJ 1998 Insulin-like growth factor I (IGF-I)-stimulated pancreatic β-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells. J Biol Chem 273:17771-17779
    • (1998) J Biol Chem , vol.273 , pp. 17771-17779
    • Hugl, S.R.1    White, M.F.2    Rhodes, C.J.3
  • 32
    • 0034463096 scopus 로고    scopus 로고
    • Follicle-stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-induced kinase (Sgk): Evidence for A kinase-independent signaling by FSH in granulosa cells
    • Gonzalez-Robayna IJ, Falender AE, Ochsner S, Firestone GL, Richards JS 2000 Follicle-stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-induced kinase (Sgk): Evidence for A kinase-independent signaling by FSH in granulosa cells. Mol Endocrinol 14:1283-1300
    • (2000) Mol Endocrinol , vol.14 , pp. 1283-1300
    • Gonzalez-Robayna, I.J.1    Falender, A.E.2    Ochsner, S.3    Firestone, G.L.4    Richards, J.S.5
  • 33
    • 0034074486 scopus 로고    scopus 로고
    • Protein kinases as mediators of phosphoinositide 3-kinase signaling
    • Toker A 2000 Protein kinases as mediators of phosphoinositide 3-kinase signaling. Mol Pharmacol 57:652-658
    • (2000) Mol Pharmacol , vol.57 , pp. 652-658
    • Toker, A.1
  • 34
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME 1999 Cellular survival: A play in three Akts. Genes Dev 13:2905-2927
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 35
    • 0035859956 scopus 로고    scopus 로고
    • p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD
    • Harada H, Andersen JS, Mann M, Terada N, Korsmeyer SJ 2001 p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD. Proc Natl Acad Sci USA 98:9666-9670
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9666-9670
    • Harada, H.1    Andersen, J.S.2    Mann, M.3    Terada, N.4    Korsmeyer, S.J.5
  • 36
    • 0032698075 scopus 로고    scopus 로고
    • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
    • Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME 1999 Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286:1358-1362
    • (1999) Science , vol.286 , pp. 1358-1362
    • Bonni, A.1    Brunet, A.2    West, A.E.3    Datta, S.R.4    Takasu, M.A.5    Greenberg, M.E.6
  • 38
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-κB activity
    • Karin M, Ben-Neriah Y 2000 Phosphorylation meets ubiquitination: The control of NF-κB activity. Annu Rev Immunol 18:621-663
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 39
    • 0035940387 scopus 로고    scopus 로고
    • In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein
    • Mehrhof FB, Muller FU, Bergmann MW, Li P, Wang Y, Schmitz W, Dietz R, von Harsdorf R 2001 In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein. Circulation 104:2088-2094
    • (2001) Circulation , vol.104 , pp. 2088-2094
    • Mehrhof, F.B.1    Muller, F.U.2    Bergmann, M.W.3    Li, P.4    Wang, Y.5    Schmitz, W.6    Dietz, R.7    Von Harsdorf, R.8
  • 40
    • 0033614021 scopus 로고    scopus 로고
    • Insulin-like growth factor I-mediated activation of the transcription factor cAMP response element-binding protein in PC12 cells. Involvement of p38 mitogen-activated protein kinase-mediated pathway
    • Pugazhenthi S, Boras T, O'Connor D, Meintzer MK, Heidenreich KA, Reusch JE 1999 Insulin-like growth factor I-mediated activation of the transcription factor cAMP response element-binding protein in PC12 cells. Involvement of p38 mitogen-activated protein kinase-mediated pathway. J Biol Chem 274:2829-2837
    • (1999) J Biol Chem , vol.274 , pp. 2829-2837
    • Pugazhenthi, S.1    Boras, T.2    O'Connor, D.3    Meintzer, M.K.4    Heidenreich, K.A.5    Reusch, J.E.6
  • 41
    • 0033600722 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein
    • Pugazhenthi S, Miller E, Sable C, Young P, Heidenreich KA, Boxer LM, Reusch JE 1999 Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein. J Biol Chem 274:27529-27535
    • (1999) J Biol Chem , vol.274 , pp. 27529-27535
    • Pugazhenthi, S.1    Miller, E.2    Sable, C.3    Young, P.4    Heidenreich, K.A.5    Boxer, L.M.6    Reusch, J.E.7
  • 42
    • 0026714673 scopus 로고
    • Phosphorylation of CREB affects its binding to high and low affinity sites: Implications for cAMP induced gene transcription
    • Nichols M, Weih F, Schmid W, DeVack C, Kowenz-Leutz E, Luckow B, Boshart M, Schutz G 1992 Phosphorylation of CREB affects its binding to high and low affinity sites: Implications for cAMP induced gene transcription. EMBO J 11:3337-3346
    • (1992) EMBO J , vol.11 , pp. 3337-3346
    • Nichols, M.1    Weih, F.2    Schmid, W.3    DeVack, C.4    Kowenz-Leutz, E.5    Luckow, B.6    Boshart, M.7    Schutz, G.8
  • 43
    • 0023712739 scopus 로고
    • Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB
    • Yamamoto KK, Gonzalez GA, Biggs 3rd WH, Montminy MR 1988 Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature 334:494-498
    • (1988) Nature , vol.334 , pp. 494-498
    • Yamamoto, K.K.1    Gonzalez, G.A.2    Biggs W.H. III3    Montminy, M.R.4
  • 44
    • 0027258139 scopus 로고
    • Multiple and cooperative phosphorylation events regulate the CREM activator function
    • de Groot RP, den Hertog J, Vandenheede JR, Goris J, Sassone-Corsi P 1993 Multiple and cooperative phosphorylation events regulate the CREM activator function. EMBO J 12:3903-3911
    • (1993) EMBO J , vol.12 , pp. 3903-3911
    • De Groot, R.P.1    Den Hertog, J.2    Vandenheede, J.R.3    Goris, J.4    Sassone-Corsi, P.5
  • 45
    • 0034463880 scopus 로고    scopus 로고
    • Increased and persistent circulating insulin-like growth factor II in neonatal transgenic mice suppresses developmental apoptosis in the pancreatic islets
    • Hill DJ, Strutt B, Arany E, Zaina S, Coukell S, Graham CF 2000 Increased and persistent circulating insulin-like growth factor II in neonatal transgenic mice suppresses developmental apoptosis in the pancreatic islets. Endocrinology 141:1151-1157
    • (2000) Endocrinology , vol.141 , pp. 1151-1157
    • Hill, D.J.1    Strutt, B.2    Arany, E.3    Zaina, S.4    Coukell, S.5    Graham, C.F.6
  • 46
    • 1642618179 scopus 로고    scopus 로고
    • Stimulation of pancreatic β-cell proliferation by growth hormone is glucose-dependent: Signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling
    • Cousin SP, Hugl SR, Myers Jr MG, White MF, Reifel-Miller A, Rhodes CJ 1999 Stimulation of pancreatic β-cell proliferation by growth hormone is glucose-dependent: Signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling. Biochem J 344:649-658
    • (1999) Biochem J , vol.344 , pp. 649-658
    • Cousin, S.P.1    Hugl, S.R.2    Myers M.G., Jr.3    White, M.F.4    Reifel-Miller, A.5    Rhodes, C.J.6
  • 47
    • 0035877778 scopus 로고    scopus 로고
    • Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor I in pancreatic β-cells (INS-1)
    • Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers Jr MG, Rhodes CJ 2001 Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor I in pancreatic β-cells (INS-1). J Biol Chem 276:21110-21120
    • (2001) J Biol Chem , vol.276 , pp. 21110-21120
    • Dickson, L.M.1    Lingohr, M.K.2    McCuaig, J.3    Hugl, S.R.4    Snow, L.5    Kahn, B.B.6    Myers M.G., Jr.7    Rhodes, C.J.8
  • 48
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ 2000 Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 10:1201-1204
    • (2000) Curr Biol , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Medema, R.H.2    Lammers, J.W.3    Koenderman, L.4    Coffer, P.J.5
  • 49
    • 0035034038 scopus 로고    scopus 로고
    • Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX
    • Brownawell AM, Kops GJ, Macara IG, Burgering BM 2001 Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. Mol Cell Biol 21:3534-3546
    • (2001) Mol Cell Biol , vol.21 , pp. 3534-3546
    • Brownawell, A.M.1    Kops, G.J.2    Macara, I.G.3    Burgering, B.M.4
  • 50
    • 0033546439 scopus 로고    scopus 로고
    • Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
    • Rena G, Guo S, Cichy SC, Unterman TG, Cohen P 1999 Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J Biol Chem 274:17179-17183
    • (1999) J Biol Chem , vol.274 , pp. 17179-17183
    • Rena, G.1    Guo, S.2    Cichy, S.C.3    Unterman, T.G.4    Cohen, P.5
  • 51
    • 0034161544 scopus 로고    scopus 로고
    • Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR
    • Nakae J, Barr V, Accili D 2000 Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR. EMBO J 19:989-996
    • (2000) EMBO J , vol.19 , pp. 989-996
    • Nakae, J.1    Barr, V.2    Accili, D.3
  • 52
    • 0034518163 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 (IGF-1): A neuroprotective trophic factor acting via the Akt kinase pathway
    • Zheng WH, Kar S, Dore S, Quirion R 2000 Insulin-like growth factor-1 (IGF-1): A neuroprotective trophic factor acting via the Akt kinase pathway. J Neural Transm 60(Suppl):261-272
    • (2000) J Neural Transm , vol.60 , Issue.SUPPL. , pp. 261-272
    • Zheng, W.H.1    Kar, S.2    Dore, S.3    Quirion, R.4
  • 53
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO 2000 The biochemistry of apoptosis. Nature 407:770-776
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 54
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
    • Zha J, Harada H, Yang E, Jockel J, Korsmeyer SJ 1996 Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L). Cell 87:619-628
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5
  • 56
    • 0032486473 scopus 로고    scopus 로고
    • Bidirectional regulation of p38 kinase and c-Jun N-terminal protein kinase by insulin-like growth factor-I
    • Cheng HL, Feldman EL 1998 Bidirectional regulation of p38 kinase and c-Jun N-terminal protein kinase by insulin-like growth factor-I. J Biol Chem 273: 14560-14565
    • (1998) J Biol Chem , vol.273 , pp. 14560-14565
    • Cheng, H.L.1    Feldman, E.L.2
  • 57
    • 0032734953 scopus 로고    scopus 로고
    • Insulin-like growth factor-I prevents caspase-mediated apoptosis in Schwann cells
    • Delaney CL, Cheng HL, Feldman EL 1999 Insulin-like growth factor-I prevents caspase-mediated apoptosis in Schwann cells. J Neurobiol 41:540-548
    • (1999) J Neurobiol , vol.41 , pp. 540-548
    • Delaney, C.L.1    Cheng, H.L.2    Feldman, E.L.3
  • 58
    • 0033179450 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and Akt protein kinase mediate IGF-I- and prosaptide-induced survival in Schwann cells
    • Campana WM, Darin SJ, O'Brien JS 1999 Phosphatidylinositol 3-kinase and Akt protein kinase mediate IGF-I- and prosaptide-induced survival in Schwann cells. J Neurosci Res 57:332-341
    • (1999) J Neurosci Res , vol.57 , pp. 332-341
    • Campana, W.M.1    Darin, S.J.2    O'Brien, J.S.3
  • 59
    • 0033553389 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart
    • Li B, Setoguchi M, Wang X, Andreoli AM, Leri A, Malhotra A, Kajstura J, Anversa P 1999 Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart. Circ Res 84:1007-1019
    • (1999) Circ Res , vol.84 , pp. 1007-1019
    • Li, B.1    Setoguchi, M.2    Wang, X.3    Andreoli, A.M.4    Leri, A.5    Malhotra, A.6    Kajstura, J.7    Anversa, P.8
  • 61
    • 0036544519 scopus 로고    scopus 로고
    • Musclespecific expression of insulin-like growth factor I counters muscle decline in mdx mice
    • Barton ER, Morris L, Musaro A, Rosenthal N, Sweeney HL 2002 Musclespecific expression of insulin-like growth factor I counters muscle decline in mdx mice. J Cell Biol 157:137-148
    • (2002) J Cell Biol , vol.157 , pp. 137-148
    • Barton, E.R.1    Morris, L.2    Musaro, A.3    Rosenthal, N.4    Sweeney, H.L.5
  • 62
    • 0033039383 scopus 로고    scopus 로고
    • Pancreatic islet cell survival following islet isolation: The role of cellular interactions in the pancreas
    • Ilieva A, Yuan S, Wang RN, Agapitos D, Hill DJ, Rosenberg L 1999 Pancreatic islet cell survival following islet isolation: The role of cellular interactions in the pancreas. J Endocrinol 161:357-364
    • (1999) J Endocrinol , vol.161 , pp. 357-364
    • Ilieva, A.1    Yuan, S.2    Wang, R.N.3    Agapitos, D.4    Hill, D.J.5    Rosenberg, L.6


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