IGF-I and GH post-receptor signaling mechanisms for pancreatic β-cell replication

Journal of Molecular Endocrinology

Volumn 24, Issue 3, 2000, Pages 303-311

  Rhodes, C J ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN C;

CELL DIVISION; CELL GROWTH; CONFERENCE PAPER; HORMONAL REGULATION; HUMAN; MITOGENESIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034130454     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0240303     Document Type: Conference Paper

References (50)

1. Argetsinger LS & Carter-Su C 1996 Mechanism of signaling by growth hormone receptor. Physiological Reviews 76 1089-1107.
2. Beattie GM, Cirulli V, Lopez AD & Hayek A 1997 Ex vivo expansion of human pancreatic endocrine cells. Journal of Clinical Endocrinology and Metabolism 82 1852-1856.
3. Belham C, Wu S & Avruch J 1999 Intracellular signalling: PDK1 - a kinase at the hub of things. Current Biology 11 R93-R96.
4. Benito M, Valverde AM & Lorenzo M 1996 IGF-I: a mitogen also involved in differentiation processes in mammalian cells. International Journal of Biochemistry and Cell Biology 28 499-510.
5. Bonner-Weir S 1992 Two pathways of β-cell growth in the regenerating rat pancreas: Implications for islet transplantation. Diabetes, Nutrition and Metabolism 5 1-3.
6. Carter-Su C & Smit LS 1998 Signaling via JAK tyrosine kinases: growth hormone receptor as a model system. Recent Progress in Hormone Research 53 61-82.
7. Cohen P 1999 The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction. Philosophical Transactions of the Royal Society Series B 354 485-495.
8. Corbett J, Serup P, Bonner-Weir S & Nielsen JH 1997 Beta-cell ontogeny: growth and death. Diabetologia 40 B27-B32.
9. Cousin SP, Hügl SR, Myers MG, White MF, Reifel-Miller A & Rhodes CJ 1999 Stimulation of pancreatic β-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription-5 (STATS) with no crosstalk to insulin-receptor substrate (IRS) mediated signalling. Biochemical Journal 344 649-658.
10. Docherty K 1991 Prospects for Gene Therapy and Cellular Engineering in Diabetes, pp 152-180. Oxford: Blackwell Scientific.
11. Efrat S 1998 Prospects for gene therapy of insulin-dependent diabetes mellitus. Diabetologia 41 1401-1419.
12. Griffin ME, Marcucci MJ, Cline GW, Bell K, Barucci N, Lee D, Goodyear LJ, Kraegen EW, White MF & Shulman GI 1999 Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes 48 1270-1274.
13. Hellerström C, Sjöholm Å & Swenne I 1991 Effects of growth hormone and related growth factors on DNA replication and insulin production in pancreatic islet β-cells. Acta Paediatrica Scandinavica 377 55-62.
14. Hohmeier H, Thigpen A, Tran V, Davis R & Newgard CB 1998 Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents cytotoxicity and reduces nitric oxide production. Journal of Clinical Investigation 101 1811-1820.
15. Hügl SR, White MF & Rhodes CJ 1998 IGF-I stimulated pancreatic β-cell growth is glucose dependent: Synergistic activation of IRS-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells. Journal of Biological Chemistry 273 17771-17779.
16. Kadowaki T, Tobe K, Honda-Yamamoto R, Tamemoto H, Kaburagi Y, Momomura K, Ueki K, Takahashi Y, Yamauchi T, Akanuma Y & Yazaki Y 1996 Signal transduction mechanism of insulin and insulin-like growth factor-I. Endocrine Journal 43 S33-S41.
17. Kane LP, Shapiro VS, Stokoe D & Weiss A 1999 Induction of NF-kappaB by the Akt/PKB kinase. Current Biology 9 601-604.
18. Kenyon NS, Chatzipetrou M, Masetti M, Ranuncoli A, Oliveira M, Wagner JL, Kirk AD, Harlan DM, Burkly LC & Ricordi C 1999 Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154. Proceedings of the National Academy of Sciences of the USA 96 8132-8137.
19. Khoo S & Cobb MH 1997 Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion. Proceedings of the National Academy of Sciences of the USA 94 5599-5604.
20. Kim SK & Melton DA 1998 Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor. Proceedings of the National Academy of Sciences of the USA 95 13036-13041.
21. Liu J-P 1996 Protein kinase C and its substrates. Molecular and Cellular Endocrinology 116 1-29.
22. Macfarlane WM, Chapman JC, Shepherd RM, Hashmi MN, Kamimura N, Cosgrove KE, O'Brien RE, Barnes PD, Hart AW, Docherty HM, Lindley KJ, Aynsley-Green A, James RF, Docherty K & Dunne MJ 1999 Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy. Journal of Biological Chemistry 274 34059-34066.
23. Myers MG, Grammer TC, Wang LM, Sun XJ, Pierce JH, Blenis J & White MF 1994 Insulin receptor substrate-1 mediates phosphatidylinositol 3′-kinase and p70S6k signaling during insulin, insulin-like growth factor-I, and interleukin-4 stimulation. Journal of Biological Chemistry 269 28783-28789.
24. Newgard CB 1994 Cellular engineering and gene therapy strategies for insulin replacement in diabetes. Diabetes 43 341-350.
25. Pick A, Clark J, Kubstrup C, Levisetti M, Pugh W, Bonner-Weir S & Polonsky KS 1998 Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. Diabetes 47 358-364.
26. Prentki M 1996 New insights into pancreatic β-cell metabolic signaling in insulin secretion. European Journal of Endocrinology 134 272-286.
27. ++, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion. Physiological Reviews 67 1185-1248.
28. Prentki M, Tornheim K & Corkey BE 1997 Signal transduction mechanisms in nutrient-induced insulin secretion. Diabetologia 40 S32-S41.
29. Rena G, Guo S, Cichy SC, Unterman TG & Cohan P 1999 Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. Journal of Biological Chemistry 274 17179-17183.
30. Robertson RP 1992 Pancreatic and islet transplantation for diabetes - cures or curiosities? New England Journal of Medicine 327 1861-1868.
31. Schmitz-Peiffer C, Craig DL & Biden TJ 1999 Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. Journal of Biological Chemistry 274 24202-24210.
32. Schuppin GT, Pons S, Hügl SR, Aiello LP, King GL, White MF & Rhodes CJ 1998 A specific increased expression of IRS-2 in pancreatic β-cell lines is involved in mediating serum stimulated β-cell growth. Diabetes 47 1074-1084.
33. Sekine N, Wollheim CB & Fujita T 1998 GH signalling in pancreatic beta-cells. Endocrine Journal 45 S33-S40.
34. Shimabukuro M, Zhou YT, Levi M & Unger RH 1998 Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes. Proceedings of the National Academy of Sciences of the USA 95 2498-2502.
35. Sjoholm A 1996 Diabetes mellitus and impaired pancreatic beta-cell proliferation. Journal of Internal Medicine 239 211-220.
36. Sjoholm A 1997 Glucose stimulates islet beta-cell mitogenesis through GTP-binding proteins and by protein kinase C-dependent mechanisms. Diabetes 46 1141-1147.
37. Slover RH & Eisenbarth GS 1997 Prevention of type I diabetes and recurrent beta-cell destruction of transplanted islets. Endocrine Reviews 18 241-258.
38. Smith FS, Rosen KM, Villa-Komaroff L, Weir GC & Bonner-Weir S 1991 Enhanced insulin-like growth factor I gene expression in the regenerating rat pancreas. Proceedings of the National Academy of Sciences of the USA 88 6152-6156.
39. Swenne I 1992 Pancreatic beta-cell growth and diabetes mellitus. Diabetologia 35 193-201.
40. Swenne I & Andersson A 1984 Effect of genetic background on the capacity for islet cell replication in mice. Diabetologia 27 464-467.
41. Swenne I, Hill DJ, Strain AJ & Milner RDG 1987 Growth hormone regulation of somatomedin S/insulin-like growth factor 1 production and DNA replication in fetal rat islets in tissue culture. Diabetes 36 288-294.
42. Thomas FT, Ricordi C, Contreras JL, Hubbard WJ, Jiang XL, Eckhoff DE, Cartner S, Bilbao G, Neville DMJ & Thomas JM 1999 Reversal of naturally occurring diabetes in primates by unmodified islet xenografts without chronic immunosuppression. Transplantation 67 846-854.
43. Unger RH 1995 Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications. Diabetes 44 863-870.
44. Weir GC & Bonner-Weir S 1997 Scientific and political impediments to successful islet transplantation. Diabetes 46 1247-1256.
45. Welsh M, Welsh N, Nilsson T, Arkammar RB, Pepinsky RB, Steiner DF & Berggren PO 1987 Stimulation of pancreatic beta cell replication by oncogenes. Proceedings of the National Academy of Sciences of the USA 85 116-120.
46. White MF 1998 The IRS-signaling system: a network of docking proteins that mediate insulin and cytokine action. Recent Progress in Hormone Research 53 119-138.
47. Withers DJ, Gutierres JS, Towery H, Ren J-M, Burks DJ, Previs S, Zhang Y, Bernal D, Pons S, Shulman GI, Bonner-Weir S & White MF 1997 Disruption of IRS-2 causes type-2 diabetes in mice. Nature 391 900-904.
48. Withers DJ, Burks DJ, Towery HH, Altamuro SL, Flint CL & White MF 1999 Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling. Nature Genetics 23 32-40.
49. Yamaoka T & Itakura M 1999 Development of pancreatic islets (Review). International Journal of Molecular Medicine 3 247-261.
50. Yenush L & White MF 1997 The IRS-signallmg system during insulin and cytokine action. BioEssays 19 491-500.